The mechanical properties of soft tissues play a key role in studying human injuries and their mitigation strategies. While such properties are indispensable for computational modelling of biological systems, they serve as important references in loading and failure experiments, and also for the development of tissue simulants. To date, experimental studies have measured the mechanical properties of peripheral tissues (e.g. skin) in-vivo and limited internal tissues ex-vivo in cadavers (e.g. brain and the heart). The lack of knowledge on a majority of human tissues inhibit their study for applications ranging from surgical planning, ballistic testing, implantable medical device development, and the assessment of traumatic injuries. The purpose of this work is to overcome such challenges through an extensive review of the literature reporting the mechanical properties of whole-body soft tissues from head to toe. Specifically, the available linear mechanical properties of all human tissues were compiled. Non-linear biomechanical models were also introduced, and the soft human tissues characterized using such models were summarized. The literature gaps identified from this work will help future biomechanical studies on soft human tissue characterization and the development of accurate medical models for the study and mitigation of injuries.

The development of foot ulcers is a common consequence of severe diabetes. Due to vascular disorders and impeded healing caused by the disease, most foot ulcers have been reported to be affected by body weight and progress with time. Also, abnormal distribution of plantar pressures has been observed to cause the formation of additional ulcers, which may collectively lead to traumatic amputations. While a study of such pathophysiology is not possible through experiments, a few computational modelling works have investigated diabetic foot ulcers. To date, ulcers with a few sizes and locations have been studied, and their effect on the plantar stresses has been quantified. In this work, we have attempted to study the effect of all possible ulcer locations on the generated plantar peak stresses and peak stress locations where additional ulcers may form. Also, the effect of ulcer location on the possible ulcer growth was investigated. A full-scale foot model was developed and a total of 52 ulcer locations were simulated separately, with standing and walking loads. The generated stresses were normalised with the foot size and statistically analysed to develop novel formulations for predicting peak plantar stresses and their locations for any known ulcer location. The results from this study are anticipated to provide important guidelines to doctors and medical practitioners for predicting foot ulcer progression in diabetic patients with existing ulcers and allow the administration of timely preventive interventions.

Slippery flooring often leads to unintentional slips and falls, which results in traumatic injuries. To reduce slipping risks, adequate traction at the shoe and flooring contact is essential. In addition, viscous slippery contaminants like water or oil reduce a floor’s traction performance and increase slipping hazards. In this work, the effect of commonly available protective floor coatings on the traction performance of safety-labelled shoes was extensively studied. The study included three floor coatings, namely acid-based etchant coating, epoxy floor paint, and polyurethane, which were tested across five safety shoes. The coated floorings were tested using a robotic slip-testing device in dry and in the presence of water and machine oil—as separate contaminants. The application of floor coatings produced varying surface roughness for the flooring. Significant traction was generated by the etchant coating for the dry flooring, epoxy coating for the wet flooring, and polyurethane coating for all flooring conditions. A comparison of uncoated and coated floorings showed a high effectiveness of generating traction with epoxy coating on wet flooring and polyurethane coating on both wet and oily conditions. The study results are novel and are anticipated to provide valuable guidelines for the selection of slip-resistant coatings for different slippery floorings, and to reduce risks related to slips and falls.