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Elżbieta Skowrońska-Jóźwiak
Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, 90-419 Lodz, Poland

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Journal article
Published: 31 July 2021 in International Journal of Environmental Research and Public Health
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Background: There is no consensus regarding vitamin sufficiency status with either 20 ng/mL or 30 ng/mL sufficiency cut-off. We assessed the effects of summer sunshine exposure on vitamin D status. Participants: We measured vitamin D concentrations, PTH, creatinine, and total calcium in 132 healthy subjects, age 29.36 ± 13.57 years, in spring and autumn. Results: There was an overall increase in vitamin D concentrations from spring to autumn from 18.1 ± 7.39 ng/mL to 24.58 ± 7.72 ng/mL, (p< 0.001), accompanied by a decrease in PTH from 44.4 ± 17.76 pg/mL to 36.6 ± 14.84 pg/mL, (p< 0.001). In spring, only 5.3% of individuals were vitamin D sufficient for a 30 ng/mL cut-off, increasing to 23.2% in autumn (p< 0.001). In contrast, when a 20 ng/mL cut-off was employed, vitamin D sufficiency was found in 34.1% in spring and 66.4% individuals in autumn, respectively, (p< 0.001). In multiple regression analysis, holiday leave was the only significant determinant of vitamin D increase (p< 0.001). Conclusions: Holiday leave is the strongest determinant of an increase in vitamin D. The majority of healthy individuals fail to reach a 30 ng/mL vitamin D cut-off after summer sunshine exposure. This raises the question, whether such a cut-off is indeed suitable for the Polish population.

ACS Style

Magdalena Basińska-Lewandowska; Andrzej Lewiński; Wojciech Horzelski; Elżbieta Skowrońska-Jóźwiak. Effect of Summer Sunshine Exposure on Vitamin D Status in Young and Middle Age Poles: Is 30 ng/mL Vitamin D Cut-Off Really Suitable for the Polish Population? International Journal of Environmental Research and Public Health 2021, 18, 8116 .

AMA Style

Magdalena Basińska-Lewandowska, Andrzej Lewiński, Wojciech Horzelski, Elżbieta Skowrońska-Jóźwiak. Effect of Summer Sunshine Exposure on Vitamin D Status in Young and Middle Age Poles: Is 30 ng/mL Vitamin D Cut-Off Really Suitable for the Polish Population? International Journal of Environmental Research and Public Health. 2021; 18 (15):8116.

Chicago/Turabian Style

Magdalena Basińska-Lewandowska; Andrzej Lewiński; Wojciech Horzelski; Elżbieta Skowrońska-Jóźwiak. 2021. "Effect of Summer Sunshine Exposure on Vitamin D Status in Young and Middle Age Poles: Is 30 ng/mL Vitamin D Cut-Off Really Suitable for the Polish Population?" International Journal of Environmental Research and Public Health 18, no. 15: 8116.

Journal article
Published: 02 July 2020 in International Journal of Environmental Research and Public Health
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Background: Depression and osteoporosis are severe public health problems. There are conflicting findings regarding the influence of depression on bone metabolism. The aim of the presented study was to compare bone turnover markers and vitamin D levels between patients treated for depression and healthy controls. Patients and Methods: We determined a concentration of osteocalcin, carboxy-terminal telopeptide of type I collagen (β-CTX), 25-hydroxyvitamin D (25OHD) and 1,25(OH)2D3 in 99 patients, aged 46.9 ± 11 years, treated for depression, as well as in 45 healthy subjects. Depressive status was determined with the Hamilton Depression Scale (HDRS). Results: In patients treated for depression, we demonstrated significantly lower osteocalcin concentrations (p < 0.03) and higher concentration of β-CTX (result on the border of significance; p = 0.08). Those relationship were stronger in women. The level of 25OHD and 1,25(OH)2D3 did not differ significantly between the examined groups. We observed a negative correlation between the 25OHD and HDRS score after treatment in all patients treated for depression and in subgroups of women and subjects with recurrent depression. Conclusions: Our results indicate that depression is related to disturbances in bone metabolism, especially in women and patients with recurrent depression, suggesting its role in context of osteoporosis development.

ACS Style

Elżbieta Skowrońska-Jóźwiak; Piotr Gałecki; Ewa Głowacka; Cezary Wojtyła; Przemysław Biliński; Andrzej Lewiński. Bone Metabolism in Patients Treated for Depression. International Journal of Environmental Research and Public Health 2020, 17, 4756 .

AMA Style

Elżbieta Skowrońska-Jóźwiak, Piotr Gałecki, Ewa Głowacka, Cezary Wojtyła, Przemysław Biliński, Andrzej Lewiński. Bone Metabolism in Patients Treated for Depression. International Journal of Environmental Research and Public Health. 2020; 17 (13):4756.

Chicago/Turabian Style

Elżbieta Skowrońska-Jóźwiak; Piotr Gałecki; Ewa Głowacka; Cezary Wojtyła; Przemysław Biliński; Andrzej Lewiński. 2020. "Bone Metabolism in Patients Treated for Depression." International Journal of Environmental Research and Public Health 17, no. 13: 4756.

Report
Published: 26 May 2020 in Chronobiology International
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Osteoporosis is an important public health problem worldwide. Although a number of factors that affect bone structure have been described; thus far, the current knowledge of occupational factors that may have an influence on bone tissue metabolism is strongly limited. Published studies indicate night shift work and the related circadian rhythm disruption may be considered as plausible underlying factors. The aim of the present study was to assess the potential association between night shift work and bone mineral density (BMD) among female blue-collar workers in Poland. A cross-sectional study was carried out among 194 female blue-collar workers >40 years of age employed in industrial plants. The operating system of work consisted of three work shifts clockwise rotation: morning (06:00–14:00 h), afternoon (14:00–22:00 h), and night (22:00–06:00 h), with five consecutive shifts per week followed by a free weekend. A questionnaire survey, based on a Polish version of The European vertebral osteoporosis study (EVOS) questionnaire, a validated instrument, was administered. Data on current job characteristics, job seniority, and lifetime duration of night shift work were also collected. BMD of the lumbar spine and hip (both total femur and femoral neck) was measured using dual-energy X-ray absorptiometry. Multivariate linear regression models were run, with bone mineralization parameters as dependent variables, as well as night work characteristics and important confounders. Statistical analysis was performed separately for premenopausal and postmenopausal women. The analyses adjusted for confounders did not reveal any significant differences between current or lifetime experience of night shift work and BMD among both premenopausal and postmenopausal women. However, the outcomes supported the well-established correlation with factors, such as age, BMI, and menopausal status. BMD at the three sites measured was significantly associated with BMI (p < .001) and inversely associated with age (p < .001) in the total study population. Postmenopausal women had significantly lower BMD than did premenopausal women (p < .001). The study findings indicate that in the population of Polish female blue-collar workers, the system of work does not seem to be associated with the development of osteoporosis.

ACS Style

Agnieszka Bukowska-Damska; Elzbieta Skowronska-Jozwiak; Pawel Kaluzny; Andrzej Lewinski; Beata Peplonska. Night shift work and osteoporosis among female blue-collar workers in Poland - a pilot study. Chronobiology International 2020, 37, 910 -920.

AMA Style

Agnieszka Bukowska-Damska, Elzbieta Skowronska-Jozwiak, Pawel Kaluzny, Andrzej Lewinski, Beata Peplonska. Night shift work and osteoporosis among female blue-collar workers in Poland - a pilot study. Chronobiology International. 2020; 37 (6):910-920.

Chicago/Turabian Style

Agnieszka Bukowska-Damska; Elzbieta Skowronska-Jozwiak; Pawel Kaluzny; Andrzej Lewinski; Beata Peplonska. 2020. "Night shift work and osteoporosis among female blue-collar workers in Poland - a pilot study." Chronobiology International 37, no. 6: 910-920.

Journal article
Published: 20 February 2019 in International Journal of Molecular Sciences
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Focal thyroid lesions are common ultrasound findings with the estimated prevalence up to 67% of the population. They form characteristically enveloped regions with individual encapsulated microenvironment that may involve the specific distribution of immune system compounds—especially antigen presenting cells (APC). We analyzed and compared the most potent APC—plasmacytoid and conventional dendritic cells (DCs) subpopulations and three monocyte subpopulations as well as other immune cells—in peripheral blood and local blood of thyroid gland obtained parallelly in patients with focal thyroid lesions using flow cytometry. The analysis revealed significant differences in the distribution of main subsets of assessed cells between peripheral blood and biopsy material. The results support the existence of local, organ-specific immune reaction control networks within thyroid nodules.

ACS Style

Mariusz Stasiołek; Przemysław W. Śliwka; Magdalena Stasiak; Kinga Krawczyk-Rusiecka; Elżbieta Skowrońska-Jóźwiak; Zbigniew Adamczewski; Andrzej Lewiński. Differences of the Structure of Immune Regulatory Cell Populations between Cellular Material from Sonographically Detected Focal Thyroid Lesions and Peripheral Blood in Humans. International Journal of Molecular Sciences 2019, 20, 918 .

AMA Style

Mariusz Stasiołek, Przemysław W. Śliwka, Magdalena Stasiak, Kinga Krawczyk-Rusiecka, Elżbieta Skowrońska-Jóźwiak, Zbigniew Adamczewski, Andrzej Lewiński. Differences of the Structure of Immune Regulatory Cell Populations between Cellular Material from Sonographically Detected Focal Thyroid Lesions and Peripheral Blood in Humans. International Journal of Molecular Sciences. 2019; 20 (4):918.

Chicago/Turabian Style

Mariusz Stasiołek; Przemysław W. Śliwka; Magdalena Stasiak; Kinga Krawczyk-Rusiecka; Elżbieta Skowrońska-Jóźwiak; Zbigniew Adamczewski; Andrzej Lewiński. 2019. "Differences of the Structure of Immune Regulatory Cell Populations between Cellular Material from Sonographically Detected Focal Thyroid Lesions and Peripheral Blood in Humans." International Journal of Molecular Sciences 20, no. 4: 918.

Journal article
Published: 01 January 2019 in Archives of Medical Science
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Introduction Polycystic ovary syndrome (PCOS), the commonest endocrinopathy of women in reproductive age, is often accompanied by insulin resistance (IR), hirsutism and/or fertility problems. The aim of the study was to assess the prevalence of IR in women diagnosed with PCOS. Material and...

ACS Style

Krzysztof Lewandowski; Elżbieta Skowrońska-Jóźwiak; Katarzyna Łukasiak; Katarzyna Gałuszko; Aleksandra Dukowicz; Magdalena Cedro; Andrzej Lewiński. How much insulin resistance in polycystic ovary syndrome? Comparison of HOMA-IR and insulin resistance (Belfiore) index models. Archives of Medical Science 2019, 15, 613 -618.

AMA Style

Krzysztof Lewandowski, Elżbieta Skowrońska-Jóźwiak, Katarzyna Łukasiak, Katarzyna Gałuszko, Aleksandra Dukowicz, Magdalena Cedro, Andrzej Lewiński. How much insulin resistance in polycystic ovary syndrome? Comparison of HOMA-IR and insulin resistance (Belfiore) index models. Archives of Medical Science. 2019; 15 (3):613-618.

Chicago/Turabian Style

Krzysztof Lewandowski; Elżbieta Skowrońska-Jóźwiak; Katarzyna Łukasiak; Katarzyna Gałuszko; Aleksandra Dukowicz; Magdalena Cedro; Andrzej Lewiński. 2019. "How much insulin resistance in polycystic ovary syndrome? Comparison of HOMA-IR and insulin resistance (Belfiore) index models." Archives of Medical Science 15, no. 3: 613-618.

Review
Published: 12 October 2018 in Chronobiology International
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Osteoporosis is an important public health problem worldwide. Among the countries with a very high population risk of fractures, there are those with the highest level of economic development. Osteoporotic fractures are the main cause of disability among elderly people, and the resultant disabilities require particularly large financial support associated not only with the direct treatment of the fracture but also with the necessity for long-term rehabilitation and care for the disabled person. Many well-established factors can have impact on bone mass and fracture risk. Recently, it has been hypothesized that working during nighttime which leads to endocrine disorders may have an indirect impact on bone physiology among night shift workers. Therefore, it can be presumed that the night shift work may contribute to the etiology of osteoporosis. The aim of our work was to make a review of the epidemiological evidence on the association between night shift work and bone mineral density or fracture risk as well as to discuss the potential biological mechanisms linking the work under this system with the development of osteoporosis. We have identified only four studies investigating the association between system of work and bone mineral density or fracture risk among workers. The findings of three out of four studies support the hypothesis. None of the studies has investigated a potential relationship between night shift work and bone turnover markers. Given that there have been no epidemiological studies in European countries that would concern working populations and the noticeable difference in the risk of osteoporosis between communities, further studies are warranted to elucidate the problem. It is presumed that further in-depth studies will not only identify the underlying factors of the disease but also contribute to developing guidelines for policy makers and employers for primary prevention of osteoporosis in workplace.

ACS Style

Agnieszka Bukowska-Damska; Elżbieta Skowrońska-Jóźwiak; Beata Peplonska. Night shift work and osteoporosis: evidence and hypothesis. Chronobiology International 2018, 36, 171 -180.

AMA Style

Agnieszka Bukowska-Damska, Elżbieta Skowrońska-Jóźwiak, Beata Peplonska. Night shift work and osteoporosis: evidence and hypothesis. Chronobiology International. 2018; 36 (2):171-180.

Chicago/Turabian Style

Agnieszka Bukowska-Damska; Elżbieta Skowrońska-Jóźwiak; Beata Peplonska. 2018. "Night shift work and osteoporosis: evidence and hypothesis." Chronobiology International 36, no. 2: 171-180.

Original article
Published: 09 August 2017 in Endocrine
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Copeptin (pre-proAVP) secreted in equimolar amounts with vasopressin closely reflects vasopressin release. Copeptin has been shown to subtly mirror stress potentially mediated via corticotrophin-releasing hormone. To further test a potential direct interaction of corticotrophin-releasing hormone with copeptin release, which could augment vasopressin effects on pituitary function, we investigated copeptin response to corticotrophin-releasing hormone. Cortisol, adrenocorticotropin and copeptin were measured in 18 healthy controls and 29 subjects with a history of pituitary disease during standard corticotrophin-releasing hormone test. Patients with previous pituitary disease were subdivided in a group passing the test (P1, n = 20) and failing (P2, n = 9). The overall copeptin response was higher in controls than in subjects with pituitary disease (area under the curve, p = 0.04 for P1 + P2) with a maximum increase in controls from 3.84 ± 2.86 to 12.65 ± 24.87 pmol/L at 30 min, p < 0.05. In contrast, both groups of pituitary patients lacked a significant copeptin response to corticotrophin-releasing hormone, and even in P1, where adrenocorticotropin concentrations increased fourfold (mean, 21.48 vs. 91.53 pg/mL, p < 0.01), copeptin did not respond (e.g., 4.35 ± 5.81 vs. 5.36 ± 6.79 pmol/L, at 30 min, p = ns). Corticotrophin-releasing hormone is able to stimulate copeptin release in healthy controls suggesting a direct interaction of corticotrophin-releasing hormone and vasopressin/vasopressin. Interestingly, this relation is altered already in the group of pituitary patients who pass the standard corticotrophin-releasing hormone test indicating (1) the corticotrophin-releasing hormone–adrenocorticotropin–cortisol response is largely independent from the vasopressin system, but (2) the corticotrophin-releasing hormone–vasopressin interaction reflected by copeptin may be much more sensitive to reveal subtle alterations in the regulation of pituitary function.

ACS Style

Krzysztof Lewandowski; Andrzej Lewiński; Elżbieta Skowrońska-Jóźwiak; Katarzyna Malicka; Wojciech Horzelski; Georg Brabant. Copeptin as a marker of an altered CRH axis in pituitary disease. Endocrine 2017, 57, 474 -480.

AMA Style

Krzysztof Lewandowski, Andrzej Lewiński, Elżbieta Skowrońska-Jóźwiak, Katarzyna Malicka, Wojciech Horzelski, Georg Brabant. Copeptin as a marker of an altered CRH axis in pituitary disease. Endocrine. 2017; 57 (3):474-480.

Chicago/Turabian Style

Krzysztof Lewandowski; Andrzej Lewiński; Elżbieta Skowrońska-Jóźwiak; Katarzyna Malicka; Wojciech Horzelski; Georg Brabant. 2017. "Copeptin as a marker of an altered CRH axis in pituitary disease." Endocrine 57, no. 3: 474-480.

Journal article
Published: 16 November 2016 in Public Health Nutrition
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ObjectiveDietary Ca is now being recognized to play an important role not only in skeletal integrity, but also in the regulation of energy and metabolism. The aim of the present study was to estimate the relationship of dairy Ca intake with BMI and blood pressure (BP) in a sample derived from the Polish population.DesignCa intake was calculated from an interviewer-administered semi-quantitative FFQ. BMI was calculated from measured weight and height, and BP was measured by a physician.SettingCross-sectional epidemiological study on osteoporosis risk factors in Poland.SubjectsRandomly selected healthy adult persons (n 1259; 750 women and 509 men).ResultsDairy Ca intake was significantly lower in individuals with overweight/obesity (BMI≥25·00 kg/m2) and/or with elevated BP (systolic/diastolic ≥140/≥90 mmHg) than in those with normal body mass and BP, respectively. Ca intake was negatively correlated with BMI (r=−0·12, Pr=−0·11, Pr=−0·08, P2 (OR=1·44, PConclusionsThe obtained results indicate the role of low dairy Ca intake in the development of obesity and hypertension, notably in premenopausal women.

ACS Style

Elżbieta Skowrońska-Jóźwiak; Maciej Jaworski; Roman Lorenc; Małgorzata Karbownik-Lewińska; Andrzej Lewiński. Low dairy calcium intake is associated with overweight and elevated blood pressure in Polish adults, notably in premenopausal women. Public Health Nutrition 2016, 20, 630 -637.

AMA Style

Elżbieta Skowrońska-Jóźwiak, Maciej Jaworski, Roman Lorenc, Małgorzata Karbownik-Lewińska, Andrzej Lewiński. Low dairy calcium intake is associated with overweight and elevated blood pressure in Polish adults, notably in premenopausal women. Public Health Nutrition. 2016; 20 (4):630-637.

Chicago/Turabian Style

Elżbieta Skowrońska-Jóźwiak; Maciej Jaworski; Roman Lorenc; Małgorzata Karbownik-Lewińska; Andrzej Lewiński. 2016. "Low dairy calcium intake is associated with overweight and elevated blood pressure in Polish adults, notably in premenopausal women." Public Health Nutrition 20, no. 4: 630-637.

Case reports
Published: 16 July 2016 in Neuro endocrinology letters
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ACS Style

Elżbieta Skowrońska-Jóźwiak; Stanislaw Sporny; Joanna Szymanska-Duda; Dominika Baranowska; Andrzej Lewinski. Hypopituitarism and goitre as endocrine manifestation of Langerhans cell histiocytosis (LCH). Case Report. Neuro endocrinology letters 2016, 37, 1 .

AMA Style

Elżbieta Skowrońska-Jóźwiak, Stanislaw Sporny, Joanna Szymanska-Duda, Dominika Baranowska, Andrzej Lewinski. Hypopituitarism and goitre as endocrine manifestation of Langerhans cell histiocytosis (LCH). Case Report. Neuro endocrinology letters. 2016; 37 (3):1.

Chicago/Turabian Style

Elżbieta Skowrońska-Jóźwiak; Stanislaw Sporny; Joanna Szymanska-Duda; Dominika Baranowska; Andrzej Lewinski. 2016. "Hypopituitarism and goitre as endocrine manifestation of Langerhans cell histiocytosis (LCH). Case Report." Neuro endocrinology letters 37, no. 3: 1.

Journal article
Published: 15 July 2016 in Annals of Agricultural and Environmental Medicine
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The objective of the study was to assess dietary calcium intake in the Polish population and its influence on selected parameters of bone tissue. 1,129 osteoporosis treatment-naive subjects, aged 20-80 years, randomly selected, were involved in the study. Bone status was established using densitometry of spine and hip and quantitative ultrasound of the calcaneus. Dietary calcium intake was calculated according to data gathered in a questionnaire. Median calcium intake was 746 mg; 72% of subjects had calcium intake below the recommended dose. Calcium intake correlated negatively with age (r = -0.15; p<0.001) and positively with BMD in the spine (r = 0.06; p<0.05) and in the femoral neck (r = 0.07; p < 0.05). In subjects with the lowest calcium intake, a significantly lower femoral neck BMD and heel stiffness was noticed than in subjects with the highest calcium intake. However, multiple regression analysis showed that dietary calcium was not a predictor of low BMD, both in the hip and spine, as well as of bone stiffness in contrast to age, low BMI and female gender (p<0.0001). In all factors regression analysis, a weak influence of calcium intake on BMD was shown only in the subgroup of premenopausal women (β = 0.1; p<0.05). In most subjects, dietary calcium intake was below the recommended dose; however, its influence on bone seems to be weak, except for persons with the greatest deficiency of dietary calcium and the subgroup of premenopausal women.

ACS Style

Elżbieta Skowrońska-Jóźwiak; Maciej Jaworski; Roman Lorenc; Andrzej Lewiński. Influence of dietary calcium intake on quantitative and qualitative parameters of bone tissue in Polish adults. Annals of Agricultural and Environmental Medicine 2016, 23, 495 -501.

AMA Style

Elżbieta Skowrońska-Jóźwiak, Maciej Jaworski, Roman Lorenc, Andrzej Lewiński. Influence of dietary calcium intake on quantitative and qualitative parameters of bone tissue in Polish adults. Annals of Agricultural and Environmental Medicine. 2016; 23 (3):495-501.

Chicago/Turabian Style

Elżbieta Skowrońska-Jóźwiak; Maciej Jaworski; Roman Lorenc; Andrzej Lewiński. 2016. "Influence of dietary calcium intake on quantitative and qualitative parameters of bone tissue in Polish adults." Annals of Agricultural and Environmental Medicine 23, no. 3: 495-501.

Original article
Published: 17 November 2015 in Endocrine
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Stimulation of growth hormone (GH) and adrenocorticotropic hormone (ACTH) secretion by glucagon is a standard procedure to assess pituitary dysfunction but the pathomechanism of glucagon action remains unclear. As arginine vasopressin (AVP) may act on the release of both, GH and ACTH, we tested here the role of AVP in GST by measuring a stable precursor fragment, copeptin, which is stoichiometrically secreted with AVP in a 1:1 ratio. ACTH, cortisol, GH, and copeptin were measured at 0, 60, 90, 120, 150, and 180 min during GST in 79 subjects: healthy controls (Group 1, n = 32), subjects with pituitary disease, but with adequate cortisol and GH responses during GST (Group 2, n = 29), and those with overt hypopituitarism (Group 3, n = 18). Copeptin concentrations significantly increased over baseline 150 and 180 min following glucagon stimulation in controls and patients with intact pituitary function but not in hypopituitarism. Copeptin concentrations were stimulated over time and the maximal increment correlated with ACTH, while correlations between copeptin and GH were weaker. Interestingly, copeptin as well as GH secretion was significantly attenuated when comparing subjects within the highest to those in the lowest BMI quartile (p < 0.05). Copeptin is significantly released following glucagon stimulation. As this release is BMI-dependent, the time-dependent relation between copeptin and GH may be obscured, whereas the close relation to ACTH suggests that AVP/copeptin release might be linked to the activation of the adrenal axis.

ACS Style

Krzysztof Lewandowski; Andrzej Lewiński; Elżbieta Skowrońska-Jóźwiak; Magdalena Stasiak; Wojciech Horzelski; Georg Brabant. Copeptin under glucagon stimulation. Endocrine 2015, 52, 344 -351.

AMA Style

Krzysztof Lewandowski, Andrzej Lewiński, Elżbieta Skowrońska-Jóźwiak, Magdalena Stasiak, Wojciech Horzelski, Georg Brabant. Copeptin under glucagon stimulation. Endocrine. 2015; 52 (2):344-351.

Chicago/Turabian Style

Krzysztof Lewandowski; Andrzej Lewiński; Elżbieta Skowrońska-Jóźwiak; Magdalena Stasiak; Wojciech Horzelski; Georg Brabant. 2015. "Copeptin under glucagon stimulation." Endocrine 52, no. 2: 344-351.

Research article
Published: 23 August 2015 in International Journal of Endocrinology
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Sclerostin, a protein expressed by osteocytes, is a negative regulator of bone formation. The aim of the study was to investigate the relationship between parathyroid hormone (PTH) and markers of bone metabolism and changes of sclerostin concentrations before and after treatment of hyperthyroidism.Patients and Methods. The study involved 33 patients (26 women), age (mean ± SD) 48 ± 15 years, with hyperthyroidism. Serum sclerostin, PTH, calcium, and bone markers [osteocalcin (OC) and collagen type I cross-linked C-telopeptide I (CTX)] were measured at diagnosis of hyperthyroidism and after treatment with thiamazole.Results. After treatment of hyperthyroidism a significant decrease in free T3(FT3) and free T4(FT4) concentrations was accompanied by marked decrease of serum sclerostin (from 43.7 ± 29.3 to 28.1 ± 18.4 pmol/L; p < 0.001 ), OC (from 35.6 ± 22.0 to 27.0 ± 14.3 ng/mL; p < 0.001 ), and CTX (from 0.49 ± 0.35 to 0.35 ± 0.23 ng/dL; p < 0.005 ), accompanied by an increase of PTH (from 29.3 ± 14.9 to 39.8 ± 19.8; p < 0.001 ). During hyperthyroidism there was a positive correlation between sclerostin and CTX ( r s = 0.41 , p < 0.05 ) and between OC and thyroid hormones (with FT3 r s = 0.42 , with FT4 r s = 0.45 , p < 0.05 ).Conclusions. Successful treatment of hyperthyroidism results in a significant decrease in serum sclerostin and bone markers concentrations, accompanied by an increase of PTH.

ACS Style

Elżbieta Skowrońska-Jóźwiak; Krzysztof Lewandowski; Zbigniew Adamczewski; Kinga Krawczyk-Rusiecka; Andrzej Lewiński. Mechanisms of Normalisation of Bone Metabolism during Recovery from Hyperthyroidism: Potential Role for Sclerostin and Parathyroid Hormone. International Journal of Endocrinology 2015, 2015, 1 -5.

AMA Style

Elżbieta Skowrońska-Jóźwiak, Krzysztof Lewandowski, Zbigniew Adamczewski, Kinga Krawczyk-Rusiecka, Andrzej Lewiński. Mechanisms of Normalisation of Bone Metabolism during Recovery from Hyperthyroidism: Potential Role for Sclerostin and Parathyroid Hormone. International Journal of Endocrinology. 2015; 2015 ():1-5.

Chicago/Turabian Style

Elżbieta Skowrońska-Jóźwiak; Krzysztof Lewandowski; Zbigniew Adamczewski; Kinga Krawczyk-Rusiecka; Andrzej Lewiński. 2015. "Mechanisms of Normalisation of Bone Metabolism during Recovery from Hyperthyroidism: Potential Role for Sclerostin and Parathyroid Hormone." International Journal of Endocrinology 2015, no. : 1-5.

Journal article
Published: 01 January 2015 in Medical Science and Technology
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ACS Style

Marlena Zajączkowska; Maria Filip; Elżbieta Skowrońska-Jóźwiak; Monika Talarowska. Rapidly Progressive Dementia as the First Symptom of Primary Hyperparathyroidism: A Case Report. Medical Science and Technology 2015, 56, 60 -65.

AMA Style

Marlena Zajączkowska, Maria Filip, Elżbieta Skowrońska-Jóźwiak, Monika Talarowska. Rapidly Progressive Dementia as the First Symptom of Primary Hyperparathyroidism: A Case Report. Medical Science and Technology. 2015; 56 ():60-65.

Chicago/Turabian Style

Marlena Zajączkowska; Maria Filip; Elżbieta Skowrońska-Jóźwiak; Monika Talarowska. 2015. "Rapidly Progressive Dementia as the First Symptom of Primary Hyperparathyroidism: A Case Report." Medical Science and Technology 56, no. : 60-65.

Journal article
Published: 31 October 2014 in Polish Archives of Internal Medicine
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ACS Style

Zbigniew Adamczewski; Marek Dedecjus; Elżbieta Skowrońska-Jóźwiak; Andrzej Lewiński. Accurate measurement of strain ratio in quasi‑static elastography. Authors' reply. Polish Archives of Internal Medicine 2014, 124, 556 -557.

AMA Style

Zbigniew Adamczewski, Marek Dedecjus, Elżbieta Skowrońska-Jóźwiak, Andrzej Lewiński. Accurate measurement of strain ratio in quasi‑static elastography. Authors' reply. Polish Archives of Internal Medicine. 2014; 124 (10):556-557.

Chicago/Turabian Style

Zbigniew Adamczewski; Marek Dedecjus; Elżbieta Skowrońska-Jóźwiak; Andrzej Lewiński. 2014. "Accurate measurement of strain ratio in quasi‑static elastography. Authors' reply." Polish Archives of Internal Medicine 124, no. 10: 556-557.

Comparative study
Published: 04 July 2014 in Polish Archives of Internal Medicine
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ACS Style

Zbigniew Adamczewski; Marek Dedecjus; Elżbieta Skowrońska‑Jóźwiak; Andrzej Lewiński. Metastases of renal clear‑cell carcinoma to the thyroid: a comparison of shear‑wave and quasi‑static elastography. Polish Archives of Internal Medicine 2014, 124, 485 -486.

AMA Style

Zbigniew Adamczewski, Marek Dedecjus, Elżbieta Skowrońska‑Jóźwiak, Andrzej Lewiński. Metastases of renal clear‑cell carcinoma to the thyroid: a comparison of shear‑wave and quasi‑static elastography. Polish Archives of Internal Medicine. 2014; 124 (9):485-486.

Chicago/Turabian Style

Zbigniew Adamczewski; Marek Dedecjus; Elżbieta Skowrońska‑Jóźwiak; Andrzej Lewiński. 2014. "Metastases of renal clear‑cell carcinoma to the thyroid: a comparison of shear‑wave and quasi‑static elastography." Polish Archives of Internal Medicine 124, no. 9: 485-486.

Journal article
Published: 01 January 2014 in Neuro endocrinology letters
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ACS Style

Elżbieta Skowrońska-Jóźwiak; Katarzyna Lebiedzińska; Joanna Smyczyńska; Krzysztof Lewandowski; Ewa Głowacka; Andrzej Lewinski. Effects of maternal vitamin D status on pregnancy outcomes, health of pregnant women and their offspring. Neuro endocrinology letters 2014, 35, 1 .

AMA Style

Elżbieta Skowrońska-Jóźwiak, Katarzyna Lebiedzińska, Joanna Smyczyńska, Krzysztof Lewandowski, Ewa Głowacka, Andrzej Lewinski. Effects of maternal vitamin D status on pregnancy outcomes, health of pregnant women and their offspring. Neuro endocrinology letters. 2014; 35 (5):1.

Chicago/Turabian Style

Elżbieta Skowrońska-Jóźwiak; Katarzyna Lebiedzińska; Joanna Smyczyńska; Krzysztof Lewandowski; Ewa Głowacka; Andrzej Lewinski. 2014. "Effects of maternal vitamin D status on pregnancy outcomes, health of pregnant women and their offspring." Neuro endocrinology letters 35, no. 5: 1.

Multicenter study
Published: 01 January 2014 in Annals of Agricultural and Environmental Medicine
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ACS Style

Elżbieta Skowrońska-Jóźwiak; Maciej Jaworski; Aneta Grzywa; Roman Lorenc; Andrzej Lewinski. Influence of calcium intake on bone mineral density and incidence of fractures in treatment-naive women from Lodz urban area - a part of EPOLOS study. Annals of Agricultural and Environmental Medicine 2014, 21, 1 .

AMA Style

Elżbieta Skowrońska-Jóźwiak, Maciej Jaworski, Aneta Grzywa, Roman Lorenc, Andrzej Lewinski. Influence of calcium intake on bone mineral density and incidence of fractures in treatment-naive women from Lodz urban area - a part of EPOLOS study. Annals of Agricultural and Environmental Medicine. 2014; 21 (1):1.

Chicago/Turabian Style

Elżbieta Skowrońska-Jóźwiak; Maciej Jaworski; Aneta Grzywa; Roman Lorenc; Andrzej Lewinski. 2014. "Influence of calcium intake on bone mineral density and incidence of fractures in treatment-naive women from Lodz urban area - a part of EPOLOS study." Annals of Agricultural and Environmental Medicine 21, no. 1: 1.

Journal article
Published: 01 January 2014 in Annals of Agricultural and Environmental Medicine
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ACS Style

Elżbieta Skowrońska-Jóźwiak; Zbigniew Adamczewski; Agnieszka Tyszkiewicz; Kinga Krawczyk-Rusiecka; Krzysztof Lewandowski; Andrzej Lewinski. Assessment of adequacy of vitamin D supplementation during pregnancy. Annals of Agricultural and Environmental Medicine 2014, 21, 1 .

AMA Style

Elżbieta Skowrońska-Jóźwiak, Zbigniew Adamczewski, Agnieszka Tyszkiewicz, Kinga Krawczyk-Rusiecka, Krzysztof Lewandowski, Andrzej Lewinski. Assessment of adequacy of vitamin D supplementation during pregnancy. Annals of Agricultural and Environmental Medicine. 2014; 21 (1):1.

Chicago/Turabian Style

Elżbieta Skowrońska-Jóźwiak; Zbigniew Adamczewski; Agnieszka Tyszkiewicz; Kinga Krawczyk-Rusiecka; Krzysztof Lewandowski; Andrzej Lewinski. 2014. "Assessment of adequacy of vitamin D supplementation during pregnancy." Annals of Agricultural and Environmental Medicine 21, no. 1: 1.

Journal article
Published: 01 January 2013 in Thyroid Research
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In order to assess safety of radioactive iodine administration in the treatment of thyrotoxicosis, we measured concentrations of matrix metalloproteinase-2 (MMP-2), its main inhibitor – TIMP-2 (tissue inhibitor of MMP-2), matrix metalloproteinase-9 (MMP-9), its main inhibitor – TIMP-1, adiponectin, as well as pro-inflammatory and procancerogenic thrombospondin-1 (TSP-1).

ACS Style

Andrzej Lewiński; Anna Brona; Krzysztof C Lewandowski; Diana Jedrzejuk; Anna Bohdanowicz-Pawlak; Elżbieta Skowrońska-Jóźwiak; Małgorzata Bienkiewicz; Andrzej Milewicz. Effects of radioiodine administration on serum concentrations of matrix metalloproteinases, adiponectin and thrombospondin-1. Thyroid Research 2013, 6, 9 -9.

AMA Style

Andrzej Lewiński, Anna Brona, Krzysztof C Lewandowski, Diana Jedrzejuk, Anna Bohdanowicz-Pawlak, Elżbieta Skowrońska-Jóźwiak, Małgorzata Bienkiewicz, Andrzej Milewicz. Effects of radioiodine administration on serum concentrations of matrix metalloproteinases, adiponectin and thrombospondin-1. Thyroid Research. 2013; 6 (1):9-9.

Chicago/Turabian Style

Andrzej Lewiński; Anna Brona; Krzysztof C Lewandowski; Diana Jedrzejuk; Anna Bohdanowicz-Pawlak; Elżbieta Skowrońska-Jóźwiak; Małgorzata Bienkiewicz; Andrzej Milewicz. 2013. "Effects of radioiodine administration on serum concentrations of matrix metalloproteinases, adiponectin and thrombospondin-1." Thyroid Research 6, no. 1: 9-9.

Journal article
Published: 01 January 2012 in Thyroid Research
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Sclerostin, a product of a SOST gene, is a protein expressed by osteocytes that inhibits osteoblastic bone formation. Several hormones, including PTH and glucocorticosteroids, have been suggested to be possible regulators of sclerostin production. The influence of thyroid hormones on sclerostin synthesis has not been investigated, so far. The aim of the study was to evaluate sclerostin concentrations in patients before and after treatment of thyrotoxicosis.

ACS Style

Elżbieta Skowrońska-Jóźwiak; Kinga Krawczyk-Rusiecka; Krzysztof C Lewandowski; Zbigniew Adamczewski; Andrzej Lewiński. Successful treatment of thyrotoxicosis is accompanied by a decrease in serum sclerostin levels. Thyroid Research 2012, 5, 14 -14.

AMA Style

Elżbieta Skowrońska-Jóźwiak, Kinga Krawczyk-Rusiecka, Krzysztof C Lewandowski, Zbigniew Adamczewski, Andrzej Lewiński. Successful treatment of thyrotoxicosis is accompanied by a decrease in serum sclerostin levels. Thyroid Research. 2012; 5 (1):14-14.

Chicago/Turabian Style

Elżbieta Skowrońska-Jóźwiak; Kinga Krawczyk-Rusiecka; Krzysztof C Lewandowski; Zbigniew Adamczewski; Andrzej Lewiński. 2012. "Successful treatment of thyrotoxicosis is accompanied by a decrease in serum sclerostin levels." Thyroid Research 5, no. 1: 14-14.