Aim: The aim was to determine the prevalence of glue‐sniffing among street children.Design: A descriptive cross‐sectional study design was adopted.Background: Children are the source of hope and could be the major ailments for the development of society, nation and the world but there are large numbers of children on the street sniff glue and struggling with multiple disease and uncertain future.Methods: A study was conducted in 52 street children to determine the prevalence of glue‐sniffers and its impact on street children in Butwal, municipality of Nepal. This study was conducted in 52 street children, 5‐ point Likert scale and interview schedule was performed with the help of structured and semi‐structured questionnaire to collect data. Finally, the collected data are analysed by using descriptive statistical methods such as frequency, percentage and mean.Results: The study findings revealed that a large number of children, that is 40.38% was between the age group of 9–12 years and 92.31% were male. The current prevalence of glue‐sniffing among street children is 88.46%. Similarly, 58.7% of respondents had started glue‐sniffing 1 year ago. Out of 46 respondents who sniffed glue, 89.13% were unaware of its effect. Nearly, half of the respondents 45.65% had encountered health issues such as headache, chest pain and stomach ache.Conclusions: They have deprived children and denied not only of their rights as children but also of their normal childhood. Without guidance, education and security, they are heading towards an uncertain future. They can have enough potentiality and talent if they are brought into a better environment and might have real hope for the bright future.

Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) affects millions of people worldwide. The article aims to review the therapeutic perspective on natural antioxidants, their mechanism of action, pharmacokinetics in management and cure of COVID‐19/ SARS‐CoV‐2 infection. We conducted a literature search including World Health Organization and National Institute of Health guidelines and clinical trials registered with ClinicalTrials.gov limited to antioxidants in COVID‐19 management. Elderly, immunocompromised patients, and others with underlying health conditions or multiple comorbidities have a high mortality rate. Disrupted redox homeostasis and oxidative stress seem to be biological pathways that may increase personal vulnerability to infection. Antioxidants like vitamins C, D, E, epigallocatechin‐3 gallate, and morin have been reported to protect against COVID‐19 disease. Reactive oxygen species are immunological regulatory elements of viral replication. Natural antioxidants exhibit potential action in preventing inflammation and organ dysfunction during viral infection. They also increase glutathione level, oxygenation rate, and immunological responses in the treatment of sepsis and acute respiratory distress syndrome. No wonder the selection of prevention, treatment, and cure of COVID‐19 and SARS‐CoV‐2 mainly depends upon the antiviral and immunoregulatory activity which they possess. Yet, their efficacy against COVID‐19 is of great concern and demands extensive study.