Anqi Chen

Dr. Anqi Chen

orcid

Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 March 2023 in Nutrients
Verified
Journal Article
Open access
PDF file
ACAnqi Chen
Anqi Chen
PGPatrick Gibney
Patrick Gibney
Trehalose is a naturally occurring, non-reducing disaccharide comprising two covalently-linked glucose molecules. It possesses unique physiochemical properties, which account for multiple biological roles in a variety of prokaryotic and eukaryotic organisms. In the past few decades, intensive research on trehalose has uncovered its functions, and extended its uses as a sweetener and stabilizer in the food, medical, pharmaceutical, and cosmetic industries. Further, increased dietary trehalose consumption has sparked research on how trehalose affects the gut microbiome. In addition to its role as a dietary sugar, trehalose has gained attention for its ability to modulate glucose homeostasis, and potentially as a therapeutic agent for diabetes. This review discusses the bioactive effects of dietary trehalose, highlighting its promise in future industrial and scientific contributions.

31 May 2024 in Food Bioscience
Verified
Journal Article
Closed access
ACAnqi Chen
Anqi Chen
TQTianzhi Qu
Tianzhi Qu
JSJeremy R. Smith
Jeremy R. Smith
JLJianghua Li
Jianghua Li
GDGuocheng Du
Guocheng Du
JCJian Chen
Jian Chen

28 December 2023 in BioDesign Research
Verified
Journal Article
Open access
YZYang Zhang
Yang Zhang
CCCheng Cheng
Cheng Cheng
BFBixia Fu
Bixia Fu
TLTeng Long
Teng Long
NHNing He
Ning He
JYJifeng Yuan
Jifeng Yuan
Lignin is one of the most widespread organic compounds found on earth, boasting a wealth of aromatic molecules. The use of lignin feedstock for biochemical productions is of great importance for achieving “carbon neutrality.” In recent years, a strategy for lignin valorization known as the “bio-funnel” has been proposed as a means to generate a variety of commercially valuable chemicals from lignin-derived compounds. The implementation of biocatalysis and metabolic engineering techniques has substantially advanced the biotransformation of depolymerized lignin into chemicals and materials within the supply chain. In this review, we present an overview of the latest advancements in microbial upcycling of depolymerized lignin into value-added chemicals. Besides, the review provides insights into the problems facing current biological lignin valorization while proposing further research directions to improve these technologies for the extensive accomplishment of the lignin upcycling.

6 January 2025 in Foods
Verified
Journal Article
Open access
PDF file
ACAnqi Chen
Anqi Chen
QSQiqi Si
Qiqi Si
QXQingyun Xu
Qingyun Xu
CPChenwei Pan
Chenwei Pan
TQTianzhi Qu
Tianzhi Qu
Jian ChenJian Chen
Jian Chen
This study evaluates the stress tolerance and metabolic adaptability of twelve yeast strains, including eleven commercial strains from Wyeast Laboratories and one prototrophic laboratory strain, under industrially relevant conditions. Yeast strains were assessed for their fermentation performance and stress responses under glucose limitation, osmotic stress, acid stress, elevated ethanol concentrations, and temperature fluctuations. Results revealed significant variability in glucose consumption, ethanol production, and stress tolerance across strains. ACY34 and ACY84 demonstrated the highest fermentation efficiency, while ACY19 exhibited exceptional stress resilience, excelling under multiple stress conditions such as osmotic and ethanol stress. The findings highlight strain-specific performance, with some strains suited for high-yield fermentation and others excelling under challenging environmental conditions. These results provide critical insights for selecting and optimizing yeast strains tailored to specific industrial fermentation processes, contributing to improved productivity and product quality in food and beverage production.


19 February 2021 in Microorganisms
Verified
Journal Article
Open access
PDF file
ACAnqi Chen
Anqi Chen
Danhui WangDanhui Wang
Danhui Wang
SNSam Nugen
Sam Nugen
JCJuhong Chen
Juhong Chen
Despite enhanced sanitation implementations, foodborne bacterial pathogens still remain a major threat to public health and generate high costs for the food industry. Reporter bacteriophage (phage) systems have been regarded as a powerful technology for diagnostic assays for their extraordinary specificity to target cells and cost-effectiveness. Our study introduced an enzyme-based fluorescent assay for detecting the presence of E. coli using the T7 phage engineered with the lacZ operon which encodes beta-galactosidase (β-gal). Both endogenous and overexpressed β-gal expression was monitored using a fluorescent-based method with 4-methylumbelliferyl β-d-galactopyranoside (MUG) as the substrate. The infection of E. coli with engineered phages resulted in a detection limit of 10 CFU/mL in ground beef juice after 7 h of incubation. In this study, we demonstrated that the overexpression of β-gal coupled with a fluorogenic substrate can provide a straightforward and sensitive approach to detect the potential biological contamination in food samples. The results also suggested that this system can be applied to detect E. coli strains isolated from environmental samples, indicating a broader range of bacterial detection.