Guido Granata

Dr. Guido Granata

Infectious Diseases Service, Campus Bio Medico University Hospital, Rome, Lazio, Italy
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orcid

Research Focus & Metrics

Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2016 in Autoimmunity Reviews
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Journal Article
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GIGIANNICOLA IANNELLA
GIANNICOLA IANNELLA
Antonio GrecoAntonio Greco
Antonio Greco
DDDario Didona
Dario Didona
BDBiagio Didona
Biagio Didona
Guido GranataGuido Granata
Guido Granata
Giuseppe MagliuloGiuseppe Magliulo
Giuseppe Magliulo

Verified
Journal Article
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Nicola PetrosilloNicola Petrosillo
Nicola Petrosillo
FTFabrizio Taglietti
Fabrizio Taglietti
Guido GranataGuido Granata
Guido Granata
Multidrug-resistant (MDR) Klebsiella pneumoniae represents an increasing threat to human health, causing difficult-to-treat infections with a high mortality rate. Since colistin is one of the few treatment options for carbapenem-resistant K. pneumoniae infections, colistin resistance represents a challenge due to the limited range of potentially available effective antimicrobials, including tigecycline, gentamicin, fosfomycin and ceftazidime/avibactam. Moreover, the choice of these antimicrobials depends on their pharmacokinetics/pharmacodynamics properties, the site of infection and the susceptibility profile of the isolated strain, and is sometimes hampered by side effects. This review describes the features of colistin resistance in K. pneumoniae and the characteristics of the currently available antimicrobials for colistin-resistant MDR K. pneumoniae, as well as the characteristics of novel antimicrobial options, such as the soon-to-be commercially available plazomicin and cefiderocol. Finally, we consider the future use of innovative therapeutic strategies in development, including bacteriophages therapy and monoclonal antibodies.

1 September 2015 in Autoimmunity Reviews
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Journal Article
Closed access
Guido GranataGuido Granata
Guido Granata
Antonio GrecoAntonio Greco
Antonio Greco
GIGIANNICOLA IANNELLA
GIANNICOLA IANNELLA
MGMassimo Granata
Massimo Granata
AMAlessandra Manno
Alessandra Manno
Giuseppe MagliuloGiuseppe Magliulo
Giuseppe Magliulo

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Giovanni PaolinoGiovanni Paolino
Giovanni Paolino
DDDario Didona
Dario Didona
Giuseppe MagliuloGiuseppe Magliulo
Giuseppe Magliulo
GIGIANNICOLA IANNELLA
GIANNICOLA IANNELLA
BDBiagio Didona
Biagio Didona
SCStefano Calvieri
Stefano Calvieri
Paraneoplastic pemphigus is a rare autoimmune skin disease that is always associated with a neoplasm. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by paraneoplastic pemphigus patients. The pathogenesis of paraneoplastic pemphigus is not yet completely understood, although some immunological aspects have been recently clarified. Because of its rarity, several diagnostic criteria have been proposed. Besides, several diagnostic procedures have been used for the diagnosis, including indirect immunofluorescence, direct immunofluorescence, and ELISA. We reviewed the most recent literature, searching on PubMed “paraneoplastic pemphigus”. We included also papers in French, German, and Spanish. We found 613 papers for “paraneoplastic pemphigus”. Among them, 169 were review papers. Because of its varying clinical features, paraneoplastic pemphigus still represents a challenge for clinicians. Furthermore, diagnosis and management of paraneoplastic pemphigus requires close collaboration between physicians, including dermatologist, oncologist, and otorhinolaryngologist.

1 August 2019 in Journal of Infection
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Journal Article
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ARAlessandro Russo
Alessandro Russo
MBMatteo Bassetti
Matteo Bassetti
Giancarlo CeccarelliGiancarlo Ceccarelli
Giancarlo Ceccarelli
NCNovella Carannante
Novella Carannante
ALAngela Raffaella Losito
Angela Raffaella Losito
MVMario Venditti
Mario Venditti

18 September 2017 in Rheumatology
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Journal Article
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EPElizabeth J. Price
Elizabeth J. Price
SRSaaeha Rauz
Saaeha Rauz
ATAnwar R. Tappuni
Anwar R. Tappuni
NSNurhan Sutcliffe
Nurhan Sutcliffe
KHKatie L. Hackett
Katie L. Hackett
SBSimon J. Bowman
Simon J. Bowman
Rheumatology 2017;56: 1643-1647