Garcinia is a genus of Clusiaceae, distributed throughout tropical Asia, Africa, New Caledonia, Polynesia, and Brazil. Garcinia plants contain a broad range of biologically active metabolites which, in the last few decades, have received considerable attention due to the chemical compositions of their extracts, with compounds which have been shown to have beneficial effects in several diseases. Our work had the objective of reviewing the benefits of five Garcinia species (G. brasiliensis, G. gardneriana, G. pedunculata, G. cambogia, and G. mangstana). These species provide a rich natural source of bioactive compounds with relevant therapeutic properties and anti-inflammatory effects, such as for the treatment of skin disorders, wounds, pain, and infections, having demonstrated antinociceptive, antioxidant, antitumoral, antifungal, anticancer, antihistaminic, antiulcerogenic, antimicrobial, antiviral, vasodilator, hypolipidemic, hepatoprotective, nephroprotective, and cardioprotective properties. This demonstrates the relevance of the genus as a rich source of compounds with valuable therapeutic properties, with potential use in the prevention and treatment of nontransmissible chronic diseases.

Background: Studies indicate that different parts of Carica papaya Linn have nutritional properties that mean it can be used as an adjuvant for the treatment of various pathologies. Methods: The fatty acid composition of the oil extracted from the seeds of Carica papaya Linn was evaluated by gas chromatography, and an acute toxicity test was performed. For the experiment, Swiss mice were fed a balanced or high-fat diet and supplemented with saline, soybean oil, olive oil, or papaya seed oil. Oral glucose tolerance and insulin sensitivity tests were performed. After euthanasia, adiposity, glycemia, total cholesterol and fractions, insulin, resistin, leptin, MCP-1, TNF-α, and IL-6 and the histology of the liver, pancreas, and adipose tissue were evaluated. Results: Papaya seed oil showed predominance of monounsaturated fatty acids in its composition. No changes were observed in the acute toxicity test. Had lower food intake in grams, and caloric intake and in the area of adipocytes without minimizing weight gain or adiposity and impacting the liver or pancreas. Reductions in total and non-HDL-c, LDL-c, and VLDL-c were also observed. The treatment had a hypoglycemic and protective effect on insulin resistance. Supplementation also resulted in higher leptin and lower insulin and cytokine resistance. Conclusions: Under these experimental conditions, papaya seed oil led to higher amounts of monounsaturated fatty acids and had hypocholesterolemic, hypotriglyceridemic, and hypoglycemic effects.

One of the main promises of solar photovoltaic technology has been the use of so-called "microinverter" which come promising to make accessible to anyone to generate their own power. This article presents a discussion of a proposal to adapt the Brazilian Standard NBR 16274 (Photovoltaic systems connected to the network - Minimum requirements for documentation, commissioning tests, inspection and performance evaluation) and NBR 16149-2013 (Interface Features connection to the electrical distribution network) and some technical standards of various utilities for correct assessment of SFCRs design methodology oriented inverter module (or microinversores). The article begins by presenting the different methodologies SFCRs projects discussing positive and negative aspects of each. Then search presents a discussion of the positive and negative aspects of SFCRs design methodology with microinverters, giving a practical example of scaling. The paper is organized as follows: Section 1 provides an introduction explaining the importance of the proposed methodology; Section 2 presents the different types of SFCRs design methodology as well as its positive and negative aspects; Section 3 describes the key differentiators of SFCRs design methodology with use of microinversores finished with practical example of scaling; Section 4 presents the main proposals to adapt and points on conflict of NBR 16274 and some standards of some utility energy company.; Section 5 presents the work's conclusions. Uma das principais promessas de tecnologias solar fotovoltaica tem sido o uso dos chamados “microinversores”, que vêm prometendo tornar acessível, a qualquer um, gerar sua própria energia. Esse artigo apresenta uma discussão de uma proposta de adaptação da Norma Brasileira ABNT NBR 16274 (Sistemas fotovoltaicos conectados á rede – Requisitos mínimos para documentação, ensaios de comissionamento, inspeção e avaliação de desempenho) e de algumas normas técnicas de diversas concessionárias para correta avaliação da metodologia de projeto de SFCRs (Sistemas Fotovoltaicos Conectados a Rede) utilizando inversor orientado ao módulo (ou microinversores). O artigo inicia apresentando as diferentes metodologias de projetos de SFCRs, discutindo aspectos positivos e negativos de cada uma. Em seguida busca apresentar uma discussão dos aspectos positivos e negativos da metodologia de projeto de SFCRs com microinversores, dando um exemplo pratico de dimensionamento. O artigo é organizado conforme segue: A Seção 1 apresenta uma introdução justificando a importância da metodologia proposta; A Seção 2 apresenta os diferentes tipos de metodologia de projeto de SFCRs bem como seus aspectos positivos e negativos; A Seção 3 descreve os principais diferenciais da metodologia de projeto de SFCRs com utilização de microinversores terminado com exemplo pratico de dimensionamento; A Seção 4 apresenta as principais propostas de adaptação e os pontos em conflito das ABNT NBR 16274 e de algumas normas técnicas de determinas concessionárias; A Seção 5 apresenta as conclusões do trabalho.

The study of medicinal plants, such as the genus Garcinia (Clusiaceae), in the treatment of non-communicable chronic diseases has aroused the interest of researchers. However, there are no studies in the literature that have investigated the effects of Garcinia gardneriana in experimental models of obesity for possible metabolic alterations. Swiss mice receiving a high-fat diet were supplemented with aqueous or ethanolic extract of G. gardneriana at doses of 200 or 400 mg/kg/day. It was found that there was a reduction in food consumption in experimental groups compared with the control groups, and the group supplemented with aqueous extract at a dose of 200 mg/kg/daydisplayed a reduction in weight. The results showed an increase in the values of high density lipoprotein (HDL-c), total cholesterol, triglycerides and fasting blood glucose. G. gardneriana did not protect against insulin resistance, and caused in an increase in monocyte chemoattractant protein-1 (MCP-1) concentrations and a reduction in interleukin 10 (IL-10). In addition, hepatic steatosis and microvesicular steatosis were indicated. It was revealed that, under the experimental conditions in the study, G. gardneriana did not prevent weight gain or comorbidities; that is, a different behavior was obtained from that described in the literature with regard to the medicinal potential of the Garcinia species, which is probably related to the phytochemical properties.