Paolo De Blasiis

Dr. Paolo De Blasiis

University of Campania "Luigi Vanvitelli", Naples, Campania, Italy
orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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20 July 2023 in Frontiers in Bioengineering and Biotechnology
Verified
Journal Article
Open access
Paolo De BlasiisPaolo De Blasiis
Paolo De Blasiis
PCP. Caravaggi
P. Caravaggi
AFA. Fullin
A. Fullin
ALA. Leardini
A. Leardini
ALA. Lucariello
A. Lucariello
ALA. De Luca
A. De Luca
Introduction: The “postural control system” acts through biomechanical strategies and functional neuromuscular adaptations to maintain body balance under static and dynamic conditions. Postural stability and body weight distribution can be affected by external sensory inputs, such as different visual stimuli. Little information is available about the influence of visual receptors on stabilometric and plantar pressure parameters. The aim of this study was to analyze variability, correlations, and changes in these parameters under open- (OE) and closed-eye (CE) conditions.Methods: A total of 31 stabilometric and plantar pressure parameters were acquired in 20 young and healthy adults during baropodometric examination performed in bipedal standing under both visual conditions. Variability of parameters was evaluated via the coefficient of variation, correlation analysis via Pearson’s R2, and statistical differences via the Wilcoxon test.Results: High intra-subject repeatability was found for all plantar pressure parameters and CoP-speed (CV < 40%) under OE and CE conditions, while CoP-sway area (CoPsa) and length surface function (LSF) showed larger variability (CV > 50%). Mean and peak pressures at midfoot and total foot loads showed the least number of significant correlations with other parameters under both visual conditions, whereas the arch-index and rearfoot loads showed the largest number of significant correlations. The limb side significantly affected most plantar pressure parameters. A trend of larger LSF and lower CoPsa and mean and peak pressures at the right forefoot was found under the CE condition.Discussion: The present study provides a deeper insight into the associations between postural stability and foot load. Interesting postural adaptations, particularly with respect to different visual stimuli, the effect of the dominant side, and the specific role of the midfoot in balance control were highlighted.

Verified
Journal Article
Open access
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Stefano PalermiStefano Palermi
Stefano Palermi
BMBruno Massa
Bruno Massa
MVMarco Vecchiato
Marco Vecchiato
FMFiore Mazza
Fiore Mazza
Paolo De BlasiisPaolo De Blasiis
Paolo De Blasiis
Felice SiricoFelice Sirico
Felice Sirico
Muscle injuries are the most common trauma in team and individual sports. The muscles most frequently affected are those of the lower limb, and in particular hamstrings, adductors, rectus femoris and calf muscles. Although several scientific studies have tried to propose different rehabilitation protocols, still too often the real rehabilitation process is not based on scientific knowledge, especially in non-elite athletes. Moreover, the growing use of physical and instrumental therapies has made it increasingly difficult to understand what can be truly effective. Therefore, the aim of the present paper is to review proposed therapeutic algorithms for muscle injuries, proposing a concise and practical summary. Following a three-phase rehabilitation protocol, this review aims to describe the conservative treatment of indirect structural muscle injuries, which are the more routinely found and more challenging type. For each phase, until return to training and return to sport are completed, the functional goal, the most appropriate practitioner, and the best possible treatment according to current evidence are expressed. Finally, the last section is focused on the specific exercise rehabilitation for the four main muscle groups with a structured explanatory timetable.

14 March 2022 in European Journal of Internal Medicine
Verified
Journal Article
Closed access
PMPasquale Mone
Pasquale Mone
APAntonella Pansini
Antonella Pansini
SFSalvatore Frullone
Salvatore Frullone
ADAntonio de Donato
Antonio de Donato
VBVeronica Buonincontri
Veronica Buonincontri
Gaetano SantulliGaetano Santulli
Gaetano Santulli

AFAllegra Fullin
Allegra Fullin
PCPaolo Caravaggi
Paolo Caravaggi
Pietro PicernoPietro Picerno
Pietro Picerno
Massimiliano MoscaMassimiliano Mosca
Massimiliano Mosca
Silvio CaravelliSilvio Caravelli
Silvio Caravelli
Paolo De BlasiisPaolo De Blasiis
Paolo De Blasiis
Background: Postural stability and plantar pressure parameters can be assessed by baropodometry; nevertheless, they are often affected by low repeatability. The aim of the study was to test the accuracy and repeatability of a novel resistive sensor pressure plate and to establish the most reliable baropodometric parameters. Methods: Accuracy and repeatability of the FM12050 BTS-Bioengineering plate measurements were assessed by using different weights in static conditions across three sessions. Subsequently, 20 healthy subjects were assessed by 30-s stabilometric analysis in bipedal standing with open eyes across four trials in two sessions, morning and afternoon. Results: Pressure plate repeatability in measuring the static weights was very high, and plate measurements were correlated to the scale measurements (Pearson’s coefficient = 0.99). Percentage of load distribution between left and right foot and in rearfoot and forefoot regions showed the largest repeatability (coefficient of variation < 5%) across trials. Eventually, median and percentiles (25–75%) were reported for each parameter. Conclusions: This study helped to assess the accuracy and repeatability of a novel pressure plate in static conditions and to define the most reliable parameters for the assessment of postural stability and foot morphology. The present healthy-subject stabilometric dataset may be used as reference data in the evaluation of pathological populations.

23 June 2022 in Genes
Verified
Journal Article
Open access
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FNFilomena Napolitano
Filomena Napolitano
MDMilena Dell'Aquila
Milena Dell'Aquila
CTChiara Terracciano
Chiara Terracciano
GFGiuseppina Franzese
Giuseppina Franzese
MGMaria Teresa Gentile
Maria Teresa Gentile
Mariarosa Anna Beatrice MeloneMariarosa Anna Beatrice Melone
Mariarosa Anna Beatrice Melone
Neurofibromatosis type 1 (NF1) is one of the most common genetic tumor predisposition syndrome, caused by mutations in the NF1. To date, few genotype-phenotype correlations have been discerned in NF1, due to a highly variable clinical presentation. We aimed to study the molecular spectrum of NF1 and genotype-phenotype correlations in a monocentric study cohort of 85 NF1 patients (20 relatives, 65 sporadic cases). Clinical data were collected at the time of the mutation analysis and reviewed for accuracy in this investigation. An internal phenotypic categorization was applied. The 94% of the patients enrolled showed a severe phenotype with at least one systemic complication and a wide range of associated malignancies. Spine deformities were the most common complications in this cohort. We also reported 66 different NF1 mutations, of which 7 are novel mutations. Correlation analysis identified a slight significant inverse correlation between age at diagnosis and delayed acquisition of psychomotor skills with residual multi-domain cognitive impairment. Odds ratio with 95% confidence interval showed a higher prevalence of learning disabilities in patients carrying frameshift mutations. Overall, our results aim to offer an interesting contribution to studies on the genotype–phenotype of NF1 and in genetic management and counselling.

1 June 2021 in Multiple Sclerosis and Related Disorders
Verified
Journal Article
Closed access
Paolo De BlasiisPaolo De Blasiis
Paolo De Blasiis
MSMaria Francesca Siani
Maria Francesca Siani
AFAllegra Fullin
Allegra Fullin
MSMario Sansone
Mario Sansone
Mariarosa Anna Beatrice MeloneMariarosa Anna Beatrice Melone
Mariarosa Anna Beatrice Melone
GLGiacomo Lus
Giacomo Lus