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The increasing cancer risk (CR) due to sediment- and soil-bound polycyclic aromatic hydrocarbons (PAHs) is one of the major threats to public health. The CR of sediment- and soil-bound carcinogenic PAHs was estimated for the first time in coastal and residential areas near an industrial zone in Korea. Monte Carlo probabilistic simulations and sensitivity tests were conducted to calculate the CR and to identify the most sensitive parameters. The CR was found to be highest in the coastal areas of Korea. Ulsan, which is located on the southeastern coast of Korea, was classified as a high cancer risk zone according to United States Environmental Protection Agency standards, while the western coast and Mohang Harbor were classified as moderate cancer risk zones. Fish consumption was identified as the main contributor (94–99%) to the total risk levels in the coastal areas. The biota-to-sediment accumulation factor (43–76%) and PAH levels (8–44%) in sediment were identified as the parameters that were most sensitive to the CR. In the residential area, the CR was found to be within the range of 10–6–10–4, which categorized it as a low cancer risk zone. Furthermore, the CR for residents in the industrial area was estimated to be 12 and 5 times higher than that for residents in the rural and urban areas, respectively. The exposure duration (55–85%) and skin adherence factor for soil (35–42%) were identified as the most sensitive parameters for the overall CR in the residential area. Korea generally has high fish and seafood consumption, which has been recognized as the most significant exposure route for CR in the studied coastal areas. Thus, the consumption of fish and seafood from coastal areas, especially those near Ulsan, might be responsible for the increasing number of cancer patients in Korea.
Debananda Roy; Woosik Jung; Jayun Kim; Minjoo Lee; Joonhong Park. Cancer Risk Levels for Sediment- and Soil-Bound Polycyclic Aromatic Hydrocarbons in Coastal Areas of South Korea. Frontiers in Environmental Science 2021, 9, 1 .
AMA StyleDebananda Roy, Woosik Jung, Jayun Kim, Minjoo Lee, Joonhong Park. Cancer Risk Levels for Sediment- and Soil-Bound Polycyclic Aromatic Hydrocarbons in Coastal Areas of South Korea. Frontiers in Environmental Science. 2021; 9 ():1.
Chicago/Turabian StyleDebananda Roy; Woosik Jung; Jayun Kim; Minjoo Lee; Joonhong Park. 2021. "Cancer Risk Levels for Sediment- and Soil-Bound Polycyclic Aromatic Hydrocarbons in Coastal Areas of South Korea." Frontiers in Environmental Science 9, no. : 1.
Seunga Kim; Jihyun Kim; Minjoo Lee; Jayun Kim; Woosik Jung; Joonhong Park. Kinetic examination on synergistic effect of co-use of ultrasonic wave and ultraviolet radiation on bacterial disinfection in a household humidifier. Journal of the Korean Society of Water and Wastewater 2021, 35, 227 -235.
AMA StyleSeunga Kim, Jihyun Kim, Minjoo Lee, Jayun Kim, Woosik Jung, Joonhong Park. Kinetic examination on synergistic effect of co-use of ultrasonic wave and ultraviolet radiation on bacterial disinfection in a household humidifier. Journal of the Korean Society of Water and Wastewater. 2021; 35 (3):227-235.
Chicago/Turabian StyleSeunga Kim; Jihyun Kim; Minjoo Lee; Jayun Kim; Woosik Jung; Joonhong Park. 2021. "Kinetic examination on synergistic effect of co-use of ultrasonic wave and ultraviolet radiation on bacterial disinfection in a household humidifier." Journal of the Korean Society of Water and Wastewater 35, no. 3: 227-235.
Non-cancer and cancer health risks to humans associated with respirable particulate matter ≤10 µm (PM10) in an indoor microenvironment such as a subway cabin are currently a public concern. In this study, detailed investigations of human health risks due to PM10-bound metals in a subway cabin were conducted for the first time. Cancer risks (CRs) were estimated for inhalation exposure (CRinh) using a Monte Carlo probability density function and were compared with incremental lifetime CRs (ILCRs). Moreover, the percentage contributions of each metal to the risk levels were calculated to identify the elements potentially responsible for human health risks. The significant (>1) for non-CRs levels as HI (hazard index) was estimated for children and adults for all types of exposure (inhalation, ingestion, and dermal). Pb, Cr, and Ni were recognized as the foremost contributors to the HQ (hazard quotient) levels for all types of exposure. For subway commuters, the CRinh and ILCR levels for adults were marginally higher than the satisfactory maximum point of confinement of the lifetime carcinogenic risk level (1 × 10−5) where as CRinh for children was within the acceptable limit (1 × 10−6–1 × 10−5). Cr was identified as the predominant carcinogenic element, with 91% contribution to the total CR level in the subway cabin on the Seoul Metropolitan Subway.
Debananda Roy; Suk Hyeon Ahn; Tae Kwon Lee; Yong-Chil Seo; Joonhong Park. Cancer and non-cancer risk associated with PM10-bound metals in subways. Transportation Research Part D: Transport and Environment 2020, 89, 102618 .
AMA StyleDebananda Roy, Suk Hyeon Ahn, Tae Kwon Lee, Yong-Chil Seo, Joonhong Park. Cancer and non-cancer risk associated with PM10-bound metals in subways. Transportation Research Part D: Transport and Environment. 2020; 89 ():102618.
Chicago/Turabian StyleDebananda Roy; Suk Hyeon Ahn; Tae Kwon Lee; Yong-Chil Seo; Joonhong Park. 2020. "Cancer and non-cancer risk associated with PM10-bound metals in subways." Transportation Research Part D: Transport and Environment 89, no. : 102618.
Jihoon Yang; Adina Howe; Jaejin Lee; Keunje Yoo; Joonhong Park. An Improved Approach to Identify Bacterial Pathogens to Human in Environmental Metagenome. Journal of Microbiology and Biotechnology 2020, 30, 1335 -1342.
AMA StyleJihoon Yang, Adina Howe, Jaejin Lee, Keunje Yoo, Joonhong Park. An Improved Approach to Identify Bacterial Pathogens to Human in Environmental Metagenome. Journal of Microbiology and Biotechnology. 2020; 30 (9):1335-1342.
Chicago/Turabian StyleJihoon Yang; Adina Howe; Jaejin Lee; Keunje Yoo; Joonhong Park. 2020. "An Improved Approach to Identify Bacterial Pathogens to Human in Environmental Metagenome." Journal of Microbiology and Biotechnology 30, no. 9: 1335-1342.
Antibiotic resistance genes (ARGs) are emerging contaminants that pose a potential threat to human health worldwide. Urban wastewater treatment plants (WWTPs) are a main source of both antibiotic-resistant bacteria and ARGs released into the environment. Nevertheless, the propagation of ARGs and their underlying mechanisms and the dynamics of mobile genetic elements (MGEs) in WWTPs have rarely been investigated in South Korea. In this study, shotgun metagenomic analysis was used to identify comprehensive ARGs and their mechanisms, bacterial communities, and MGEs from 4 configurations with 2 activated sludge (AS) and 2 anaerobic digestion sludge (ADS) samples. A total of 181 ARG subtypes belonging to 22 ARG types were broadly detected, and the ARG abundances in the AS samples were 1.3–2.0 orders of magnitude higher than in the ADS samples. Multidrug and bacitracin resistance genes were the predominant ARG types in AS samples, followed by ARGs against sulfonamide, tetracycline, and β-lactam. However, the composition of ARG types in ADS samples was significantly changed. The abundance of multidrug and β-lactam resistance genes was drastically reduced in the ADS samples. The resistance genes of MLS were the predominant, followed by ARGs against sulfonamide and tetracycline in the ADS samples. In addition, plasmids were the dominant MGEs in the AS samples, while integrons (intI1) were the dominant MGEs in the ADS samples. These results provide valuable information regarding the prevalence of ARG types and MGEs and the difference patterns between the AS and ADS systems.
Keunje Yoo; Hyunji Yoo; Jangho Lee; Eun Joo Choi; Joonhong Park. Exploring the antibiotic resistome in activated sludge and anaerobic digestion sludge in an urban wastewater treatment plant via metagenomic analysis. Journal of Microbiology 2019, 58, 123 -130.
AMA StyleKeunje Yoo, Hyunji Yoo, Jangho Lee, Eun Joo Choi, Joonhong Park. Exploring the antibiotic resistome in activated sludge and anaerobic digestion sludge in an urban wastewater treatment plant via metagenomic analysis. Journal of Microbiology. 2019; 58 (2):123-130.
Chicago/Turabian StyleKeunje Yoo; Hyunji Yoo; Jangho Lee; Eun Joo Choi; Joonhong Park. 2019. "Exploring the antibiotic resistome in activated sludge and anaerobic digestion sludge in an urban wastewater treatment plant via metagenomic analysis." Journal of Microbiology 58, no. 2: 123-130.
To improve stability of nitrogen removal in partial nitritation (PN)-anammox process, flat-type cryogel films using poly (vinylalcohol) named as FT-CPVAF were applied in continuous reactors. Stable PN operation was maintained with short acclimation of 8 days and ammonium oxidation rate of 1.68 ± 0.12 kg N m−3 d−1 comparatively higher than previous studies. The nitrogen removal, initially inhibited by an oxygen shock, was immediately reactivated with short lag-period by immobilization of anammox bacteria in FT-CPVAF. A novel two-stage PN-anammox process was operated in a continuous flow using FT-CPVAF for treatment of ammonium-rich synthetic wastewater (influent 315 mg NH4+-N L−1) showing 89.6 ± 0.76% of nitrogen removal at short hydraulic retention time (7.7 h). The use of FT-CPVAF enhanced selective enrichment of AOB and anammox bacter ia confirmed by high-throughput sequencing of i.e., relative abundances of Nitrosomonas europaea C-31 (37.14% in PN reactor) and ‘Candidatus Jettenia caeni’ (34.36% in anammox reactor).
Minkyu Choi; Ramjee Chaudhary; Minjoo Lee; Jihyun Kim; Kyungjin Cho; Yun-Chul Chung; Hyokwan Bae; Joonhong Park. Enhanced selective enrichment of partial nitritation and anammox bacteria in a novel two-stage continuous flow system using flat-type poly (vinylalcohol) cryogel films. Bioresource Technology 2019, 300, 122546 .
AMA StyleMinkyu Choi, Ramjee Chaudhary, Minjoo Lee, Jihyun Kim, Kyungjin Cho, Yun-Chul Chung, Hyokwan Bae, Joonhong Park. Enhanced selective enrichment of partial nitritation and anammox bacteria in a novel two-stage continuous flow system using flat-type poly (vinylalcohol) cryogel films. Bioresource Technology. 2019; 300 ():122546.
Chicago/Turabian StyleMinkyu Choi; Ramjee Chaudhary; Minjoo Lee; Jihyun Kim; Kyungjin Cho; Yun-Chul Chung; Hyokwan Bae; Joonhong Park. 2019. "Enhanced selective enrichment of partial nitritation and anammox bacteria in a novel two-stage continuous flow system using flat-type poly (vinylalcohol) cryogel films." Bioresource Technology 300, no. : 122546.
Bacterial communities in wastewater treatment plants (WWTPs) affect plant functionality through their role in the removal of pollutants from wastewater. Bacterial communities vary extensively based on plant operating conditions and influent characteristics. The capacity of WWTPs can also affect the bacterial community via variations in the organic or nutrient composition of the influent. Despite the importance considering capacity, the characteristics that control bacterial community assembly are largely unknown. In this study, we discovered that bacterial communities in WWTPs in Korea and Vietnam, which differ remarkably in capacity, exhibit unique structures and interactions that are governed mainly by the capacity of WWTPs. Bacterial communities were analysed using 16S rRNA gene sequencing and exhibited clear differences between the two regions, with these differences being most pronounced in activated sludge. We found that capacity contributed the most to bacterial interactions and community structure, whereas other factors had less impact. Co-occurrence network analysis showed that microorganisms from high-capacity WWTPs are more interrelated than those from low-capacity WWTPs, which corresponds to the tighter clustering of bacterial communities in Korea. These results will contribute to the understanding of bacterial community assembly in activated sludge processing.
Young Kyung Kim; Keunje Yoo; Min Sung Kim; Il Han; Minjoo Lee; Bo Ram Kang; Tae Kwon Lee; Joonhong Park. The capacity of wastewater treatment plants drives bacterial community structure and its assembly. Scientific Reports 2019, 9, 1 -9.
AMA StyleYoung Kyung Kim, Keunje Yoo, Min Sung Kim, Il Han, Minjoo Lee, Bo Ram Kang, Tae Kwon Lee, Joonhong Park. The capacity of wastewater treatment plants drives bacterial community structure and its assembly. Scientific Reports. 2019; 9 (1):1-9.
Chicago/Turabian StyleYoung Kyung Kim; Keunje Yoo; Min Sung Kim; Il Han; Minjoo Lee; Bo Ram Kang; Tae Kwon Lee; Joonhong Park. 2019. "The capacity of wastewater treatment plants drives bacterial community structure and its assembly." Scientific Reports 9, no. 1: 1-9.
This study compared the performance of microalga growth, nutrient removal, algal organic matter, and energy storage products in mixotrophic, photoautotrophic, and heterotrophic conditions. Scenedesmus obliquus was used as a model species. Mixotrophic condition showed the highest specific growth rate of 0.96 d−1 as well as the fastest nitrogen and phosphorus removal rate of 85.17 mg-N g-cell−1 day−1 and 11.49 mg-P g-cell−1 day−1, respectively, compared with photoautotrophic and heterotrophic conditions. Mixotrophic microalgae had relatively higher carbohydrates and lipids contents (21.8 and 24.0%) than photoautotrophic and heterotrophic conditions. Meanwhile, algal organic matter (AOM) in the medium was produced at the highest level under photoautotrophic condition. Mixotrophic condition was more efficient in terms of microalga growth, nutrient removal, production of energy storage products, and suppression of AOM, and would be adaptable for wastewater treatment process.
Wook Jin Choi; A. Na Chae; Kyung Guen Song; Joonhong Park; Byung Chan Lee. Effect of trophic conditions on microalga growth, nutrient removal, algal organic matter, and energy storage products in Scenedesmus (Acutodesmus) obliquus KGE-17 cultivation. Bioprocess and Biosystems Engineering 2019, 42, 1225 -1234.
AMA StyleWook Jin Choi, A. Na Chae, Kyung Guen Song, Joonhong Park, Byung Chan Lee. Effect of trophic conditions on microalga growth, nutrient removal, algal organic matter, and energy storage products in Scenedesmus (Acutodesmus) obliquus KGE-17 cultivation. Bioprocess and Biosystems Engineering. 2019; 42 (7):1225-1234.
Chicago/Turabian StyleWook Jin Choi; A. Na Chae; Kyung Guen Song; Joonhong Park; Byung Chan Lee. 2019. "Effect of trophic conditions on microalga growth, nutrient removal, algal organic matter, and energy storage products in Scenedesmus (Acutodesmus) obliquus KGE-17 cultivation." Bioprocess and Biosystems Engineering 42, no. 7: 1225-1234.
Asian dust (AD) events have received significant attention due to their adverse effects on ecosystems and human health. However, detailed information about airborne pathogens associated with AD events is limited. This study monitored airborne bacterial communities and identified AD-specific bacteria and the potential hazards associated with these bacteria during AD events. Over a 33-month period, 40 air samples were collected under normal atmospheric conditions (non-AD events; n = 34) and during AD events (n = 6). The airborne bacterial communities in the air samples collected during non-AD events (non-AD sample) and AD events (AD sample) were evaluated using both culture-dependent and culture-independent methods. The bacterial diversity increased significantly, along with the 16S rRNA gene copy number, in AD samples (p < 0.05) and was positively correlated with PM10 concentration. High throughput sequencing of the 16S rRNA gene revealed that the relative abundance of the phylum Firmicutes increased substantially in AD samples (44.3 ± 5.0%) compared with non-AD samples (27.8 ± 4.3%). Within the phylum Firmicutes, AD samples included a greater abundance of Bacillus species (almost 23.8%) than non-AD samples (almost 13.3%). Both culture-dependent and culture-independent methods detected common predominant species closely related to Bacillus cereus during AD events. Subsequent multilocus sequence typing (MLST) and enterotoxin gene assays confirmed the presence of virulence factors in B. cereus isolates from AD samples. Furthermore, the abundance of bceT, encoding enterotoxin in B. cereus, was significantly higher in AD samples (p < 0.05). The systematic characterization of airborne bacterial communities in AD samples in this study suggests that B. cereus pose risks to public health.
Keunje Yoo; Il Han; Kwan Soo Ko; Tae Kwon Lee; Hyunji Yoo; Muhammad Imran Khan; James M. Tiedje; Joonhong Park. Bacillus-Dominant Airborne Bacterial Communities Identified During Asian Dust Events. Microbial Ecology 2019, 78, 677 -687.
AMA StyleKeunje Yoo, Il Han, Kwan Soo Ko, Tae Kwon Lee, Hyunji Yoo, Muhammad Imran Khan, James M. Tiedje, Joonhong Park. Bacillus-Dominant Airborne Bacterial Communities Identified During Asian Dust Events. Microbial Ecology. 2019; 78 (3):677-687.
Chicago/Turabian StyleKeunje Yoo; Il Han; Kwan Soo Ko; Tae Kwon Lee; Hyunji Yoo; Muhammad Imran Khan; James M. Tiedje; Joonhong Park. 2019. "Bacillus-Dominant Airborne Bacterial Communities Identified During Asian Dust Events." Microbial Ecology 78, no. 3: 677-687.
Since the analysis of a large number of metagenomic sequences costs heavy computing resources and takes long time, we examined a selected small part of metagenomic sequences as “sample”s of the entire full sequences, both for a mock community and for 10 different existing metagenomics case studies. A mock community with 10 bacterial strains was prepared, and their mixed genome were sequenced by Hiseq. The hits of BLAST search for reference genome of each strain were counted. Each of 176 different small parts selected from these sequences were also searched by BLAST and their hits were also counted, in order to compare them to the original search results from the full sequences. We also prepared small parts of sequences which were selected from 10 publicly downloadable research data of MG-RAST service, and analyzed these samples with MG-RAST. Both the BLAST search tests of the mock community and the results from the publicly downloadable researches of MG-RAST show that sampling an extremely small part from sequence data is useful to estimate brief taxonomic information of the original metagenomic sequences. For 9 cases out of 10, the most annotated classes from the MG-RAST analyses of the selected partial sample sequences are the same as the ones from the originals. When a researcher wants to estimate brief information of a metagenome’s taxonomic distribution with less computing resources and within shorter time, the researcher can analyze a selected small part of metagenomic sequences. With this approach, we can also build a strategy to monitor metagenome samples of wider geographic area, more frequently. The online version of this article (10.1186/s12859-018-2431-8) contains supplementary material, which is available to authorized users.
Jaesik Kwak; Joonhong Park. What we can see from very small size sample of metagenomic sequences. BMC Bioinformatics 2018, 19, 399 .
AMA StyleJaesik Kwak, Joonhong Park. What we can see from very small size sample of metagenomic sequences. BMC Bioinformatics. 2018; 19 (1):399.
Chicago/Turabian StyleJaesik Kwak; Joonhong Park. 2018. "What we can see from very small size sample of metagenomic sequences." BMC Bioinformatics 19, no. 1: 399.
Methane oxidation coupled to denitrification (MOD) was tested in a membrane biofilm reactor (MBfR) using methane gas as the sole electron donor. Nitrate reduction to nitrite was rate limiting, and CH4 was present in the effluent. Slow kinetics of methane oxidation by bacteria were the factors that led to slow kinetics and incomplete removals. Methylocystaceae contained the largest fraction (21%) of bacterial SSU rRNA genes, and Archaea were nearly absent. The functional metagenome included all the genes essential for aerobic methane oxidation (pmo, mdh, mtdB, folD, and fdh) and nitrate reduction to dinitrogen (nap/nar, nir, nor and nos), but not for reverse methanogenesis (mcr). The functional metagenome supports that Methylocystaceae conducted MOD in syntrophy with heterotrophic denitrifiers (e.g., Comamonadaceae and Brucellaceae), suggesting aerobic MOD. DO measurements, serum-bottle tests, and calculation of O2 permeation bolster hypoxically aerobic MOD would mainly account for denitrification in the MBfR.
Wael Alrashed; Jangho Lee; Joonhong Park; Bruce E. Rittmann; YouNeng Tang; Josh D. Neufeld; Hyung-Sool Lee. Hypoxic methane oxidation coupled to denitrification in a membrane biofilm. Chemical Engineering Journal 2018, 348, 745 -753.
AMA StyleWael Alrashed, Jangho Lee, Joonhong Park, Bruce E. Rittmann, YouNeng Tang, Josh D. Neufeld, Hyung-Sool Lee. Hypoxic methane oxidation coupled to denitrification in a membrane biofilm. Chemical Engineering Journal. 2018; 348 ():745-753.
Chicago/Turabian StyleWael Alrashed; Jangho Lee; Joonhong Park; Bruce E. Rittmann; YouNeng Tang; Josh D. Neufeld; Hyung-Sool Lee. 2018. "Hypoxic methane oxidation coupled to denitrification in a membrane biofilm." Chemical Engineering Journal 348, no. : 745-753.
Despite progress in monitoring and modeling Asian dust (AD) events, real-time public hazard prediction based on biological evidence during AD events remains a challenge. Herein, both a classification and regression tree (CART) and multiple linear regression (MLR) were applied to assess the applicability of prediction for potential urban airborne bacterial hazards during AD events using metagenomic analysis and real-time qPCR. In the present work, Bacillus cereus was screened as a potential pathogenic candidate and positively correlated with PM10 concentration (p < 0.05). Additionally, detection of the bceT gene with qPCR, which codes for an enterotoxin in B. cereus, was significantly increased during AD events (p < 0.05). The CART approach more successfully predicted potential airborne bacterial hazards with a relatively high coefficient of determination (R2) and small bias, with the smallest root mean square error (RMSE) and mean absolute error (MAE) compared to the MLR approach. Regression tree analyses from the CART model showed that the PM10 concentration, from 78.4 µg/m3 to 92.2 µg/m3, is an important atmospheric parameter that significantly affects the potential airborne bacterial hazard during AD events. The results show that the CART approach may be useful to effectively derive a predictive understanding of potential airborne bacterial hazards during AD events and thus has a possible for improving decision-making tools for environmental policies associated with air pollution and public health.
Keunje Yoo; Hyunji Yoo; Jae Min Lee; Sudheer Kumar Shukla; Joonhong Park. Classification and Regression Tree Approach for Prediction of Potential Hazards of Urban Airborne Bacteria during Asian Dust Events. Scientific Reports 2018, 8, 1 -11.
AMA StyleKeunje Yoo, Hyunji Yoo, Jae Min Lee, Sudheer Kumar Shukla, Joonhong Park. Classification and Regression Tree Approach for Prediction of Potential Hazards of Urban Airborne Bacteria during Asian Dust Events. Scientific Reports. 2018; 8 (1):1-11.
Chicago/Turabian StyleKeunje Yoo; Hyunji Yoo; Jae Min Lee; Sudheer Kumar Shukla; Joonhong Park. 2018. "Classification and Regression Tree Approach for Prediction of Potential Hazards of Urban Airborne Bacteria during Asian Dust Events." Scientific Reports 8, no. 1: 1-11.
In this study, anammox enrichment reactors were operated using flat type poly (vinyl alcohol) cryogel (cryoPVAG) with precultured anammox bacteria (PAB) and activated sludge (AS) from an anoxic tack of the A2O process to evaluate the effect of different seeding sources on anammox enrichment. In addition, cryoPVAGs with different thicknesses (1, 2, and 3 mm) were used to investigate the effects of the thickness on anammox enrichment. The regression analysis with a modified Gompertz model showed that the start-up period of the anammox enrichment using PAB inoculum was approximately 14 days earlier than that of AS inoculum at a nitrogen loading rate of approximately 1 kg-N m−3 day−1. Substrate diffusion was limited in 3-mm cryoPVAG with respect to trend in nitrogen removal rate. Quantitative PCR analysis indicated that in the initial phase, the 16S rRNA gene copy numbers of anammox microorganism in cryoPVAG were significantly different according to the seeding source, but finally converged to a similar level after anammox enrichment. The anammox reaction was initially promoted by cryoPVAG. Next, anammox biomass detached from cryoPVAG and enriched in the bulk phase to maximize NRR. Illumina MiSeq sequencing revealed that Candidatus Brocadia sinica led to the active anammox reaction, and its relative abundance decreased with increasing gel thickness.
Minkyu Choi; Kyungjin Cho; Seockheon Lee; Yun-Chul Chung; Joonhong Park; Hyokwan Bae. Effective seeding strategy using flat type poly (vinyl alcohol) cryogel for anammox enrichment. Chemosphere 2018, 205, 88 -97.
AMA StyleMinkyu Choi, Kyungjin Cho, Seockheon Lee, Yun-Chul Chung, Joonhong Park, Hyokwan Bae. Effective seeding strategy using flat type poly (vinyl alcohol) cryogel for anammox enrichment. Chemosphere. 2018; 205 ():88-97.
Chicago/Turabian StyleMinkyu Choi; Kyungjin Cho; Seockheon Lee; Yun-Chul Chung; Joonhong Park; Hyokwan Bae. 2018. "Effective seeding strategy using flat type poly (vinyl alcohol) cryogel for anammox enrichment." Chemosphere 205, no. : 88-97.
One of water utility’s managerial challenges is to make a balance in between two distinctive managerial goals, cost-effective provision of water service and improving customer satisfaction of water service. As management priorities of the water utility perspective do not reconcile from the customer’s perspective, this gap challenges the sustainable provision of water service. In this study, the new methodology based on a gap analysis was proposed to improve the Overall Level of Service (O-LOS) of water service. Two new indexes (Gap Index [GI] and the Efficiency Index [EI]) were developed to improve the O-LOS and minimize the gap between the customers and the service providers. The methodology proposed in this study is effective in supporting the water utility decisions on budget allocation to make a balance in between the customers’ demand and the service providers’ needs.
Sangjong Han; Dan Daehyun Koo; Youngkyung Kim; Seonghoon Kim; Joonhong Park. Gap Analysis Based Decision Support Methodology to Improve Level of Service of Water Services. Sustainability 2017, 9, 1578 .
AMA StyleSangjong Han, Dan Daehyun Koo, Youngkyung Kim, Seonghoon Kim, Joonhong Park. Gap Analysis Based Decision Support Methodology to Improve Level of Service of Water Services. Sustainability. 2017; 9 (9):1578.
Chicago/Turabian StyleSangjong Han; Dan Daehyun Koo; Youngkyung Kim; Seonghoon Kim; Joonhong Park. 2017. "Gap Analysis Based Decision Support Methodology to Improve Level of Service of Water Services." Sustainability 9, no. 9: 1578.
Background DNA mismatch repair deficiency is an important molecular mechanism of genetic instability in gastric cancer, and a high instability at microsatellites is associated with favorable prognosis. We compared mononucleotide and dinucleotide microsatellite instability (MSI) marker panels in 56 paired gastric tumor and normal samples. Methods The mononucleotide marker panel (mono panel) consisted of 8 markers: BAT25, BAT26, BAT40, BAT-RII, NR21, NR22, NR24 and NR27. The dinucleotide marker panel (di panel) contained D2S123, D5S346, D17S250, D17S261, D17S520, D18S34 and D18S58. The NCI panel was used as reference panel. Results Among 13 gastric tumors showing no hMLH1 or hMSH2 expression, 8 MSI-H (high) and 5 MSI-L (low) were identified. The analytical sensitivities of the NCI, mono and di panels to detect unstable MSI were 61.5% (8/13), 76.9% (10/13) and 84.6% (11/13), respectively. The size change of allele shift was statistically greater in the mono panel than in the di panel (p = 0.02 by Mann-Whitney U-test). The BAT40 (69.2%, 9/13) and D18S34 (76.9%, 10/13) markers showed high sensitivity for determination of MSI status. Conclusions To improve the detection rate of MSI in gastric cancer with loss of hMLH1 or hMSH2 expression, the kind of MSI marker may need to be considered more, instead of the repetitive type of marker. Thus, an MSI panel designed with a combination of both BAT40 and D18S34 is suggested for providing more accurate and sensitive MSI analysis in gastric cancer.
Jeong Goo Kim; Soyoung Shin; Joonhong Park. Comparison between Mononucleotide and Dinucleotide Marker Panels in Gastric Cancer with Loss of hMLH1 or hMSH2 Expression. The International Journal of Biological Markers 2017, 32, 352 -356.
AMA StyleJeong Goo Kim, Soyoung Shin, Joonhong Park. Comparison between Mononucleotide and Dinucleotide Marker Panels in Gastric Cancer with Loss of hMLH1 or hMSH2 Expression. The International Journal of Biological Markers. 2017; 32 (3):352-356.
Chicago/Turabian StyleJeong Goo Kim; Soyoung Shin; Joonhong Park. 2017. "Comparison between Mononucleotide and Dinucleotide Marker Panels in Gastric Cancer with Loss of hMLH1 or hMSH2 Expression." The International Journal of Biological Markers 32, no. 3: 352-356.
Carbon-fiber-reinforced thermoplastic (CFRTP) laminate undergoes large deformations and slip between each layer during the prepreg compression forming (PCF) process. Particularly, the formability of CFRTPs varies for each layer as a result of the temperature difference during heat transfer between tool and laminate because of the viscosity of resin. These behaviors affect the final product quality and may create related defects such as wrinkling, and delamination. The objective of this study is to predict the defects by using the finite element method (FEM) considering the heat transfer according to the forming temperature. The bias extension were performed to measure the shrar properties (which are dependent on temperature) at 150°C, 170°C, and 190°C. In addition, the heat transfer coefficient between tool and laminate was measured using the inverse analysis method. The effect of tool temperature on formability of CFRTP prepreg was investigated by FE analysis of the hemispherical punch drawing test. To verify the reliability of the FE analysis, hemispherical punch drawing experiments were performed under the same conditions as those of the FE analysis. The deformed shear angle of CFRTP specimens in the experiment were compared with simulation results. Finally, the temperatures were evaluated to investigate the effects of temperature variation caused by heat transfer.
Jeong-Min Lee; Byung-Min Kim; Byeong-Jin Min; Joon-Hong Park; Dae-Cheol Ko. Formability of CFRTP prepreg considering heat transfer. International Journal of Precision Engineering and Manufacturing-Green Technology 2017, 4, 161 -168.
AMA StyleJeong-Min Lee, Byung-Min Kim, Byeong-Jin Min, Joon-Hong Park, Dae-Cheol Ko. Formability of CFRTP prepreg considering heat transfer. International Journal of Precision Engineering and Manufacturing-Green Technology. 2017; 4 (2):161-168.
Chicago/Turabian StyleJeong-Min Lee; Byung-Min Kim; Byeong-Jin Min; Joon-Hong Park; Dae-Cheol Ko. 2017. "Formability of CFRTP prepreg considering heat transfer." International Journal of Precision Engineering and Manufacturing-Green Technology 4, no. 2: 161-168.
Joonhong Park; Soyoung Shin; Han Mo Yoo; Seung-Woo Lee; Jeong Goo Kim. Evaluation of the Three Customized MSI Panels to Improve the Detection of Microsatellite Instability in Gastric Cancer. Clinical Laboratory 2017, 63, 705 -716.
AMA StyleJoonhong Park, Soyoung Shin, Han Mo Yoo, Seung-Woo Lee, Jeong Goo Kim. Evaluation of the Three Customized MSI Panels to Improve the Detection of Microsatellite Instability in Gastric Cancer. Clinical Laboratory. 2017; 63 (4):705-716.
Chicago/Turabian StyleJoonhong Park; Soyoung Shin; Han Mo Yoo; Seung-Woo Lee; Jeong Goo Kim. 2017. "Evaluation of the Three Customized MSI Panels to Improve the Detection of Microsatellite Instability in Gastric Cancer." Clinical Laboratory 63, no. 4: 705-716.
Jeongwon Lee; Yoorae Noh; Joonhong Park. Influences of pH on Heavy Metal Leaching in Water Supply Pipelines. Journal of The Korean Society of Civil Engineers 2017, 37, 73 -82.
AMA StyleJeongwon Lee, Yoorae Noh, Joonhong Park. Influences of pH on Heavy Metal Leaching in Water Supply Pipelines. Journal of The Korean Society of Civil Engineers. 2017; 37 (1):73-82.
Chicago/Turabian StyleJeongwon Lee; Yoorae Noh; Joonhong Park. 2017. "Influences of pH on Heavy Metal Leaching in Water Supply Pipelines." Journal of The Korean Society of Civil Engineers 37, no. 1: 73-82.
Jeong-Min Lee; Byung-Min Kim; Sang-Kon Lee; Joon-Hong Park; Dae-Cheol Ko. A study on the process design of prepreg compression forming using rapid heating and cooling system. Procedia Engineering 2017, 207, 84 -89.
AMA StyleJeong-Min Lee, Byung-Min Kim, Sang-Kon Lee, Joon-Hong Park, Dae-Cheol Ko. A study on the process design of prepreg compression forming using rapid heating and cooling system. Procedia Engineering. 2017; 207 ():84-89.
Chicago/Turabian StyleJeong-Min Lee; Byung-Min Kim; Sang-Kon Lee; Joon-Hong Park; Dae-Cheol Ko. 2017. "A study on the process design of prepreg compression forming using rapid heating and cooling system." Procedia Engineering 207, no. : 84-89.
Bioaerosols significantly affect atmospheric processes while they undergo long-range vertical and horizontal transport and influence atmospheric chemistry and physics and climate change. Accumulating evidence suggests that exposure to bioaerosols may cause adverse health effects, including severe disease. Studies of bioaerosols have primarily focused on their chemical composition and largely neglected their biological composition and the negative effects of biological composition on ecosystems and human health. Here, current molecular methods for the identification, quantification, and distribution of bioaerosol agents are reviewed. Modern developments in environmental microbiology technology would be favorable in elucidation of microbial temporal and spatial distribution in the atmosphere at high resolution. In addition, these provide additional supports for growing evidence that microbial diversity or composition in the bioaerosol is an indispensable environmental aspect linking with public health.
Keunje Yoo; Tae Kwon Lee; Eun Joo Choi; Jihoon Yang; Sudheer Kumar Shukla; Sang-Il Hwang; Joonhong Park. Molecular approaches for the detection and monitoring of microbial communities in bioaerosols: A review. Journal of Environmental Sciences 2017, 51, 234 -247.
AMA StyleKeunje Yoo, Tae Kwon Lee, Eun Joo Choi, Jihoon Yang, Sudheer Kumar Shukla, Sang-Il Hwang, Joonhong Park. Molecular approaches for the detection and monitoring of microbial communities in bioaerosols: A review. Journal of Environmental Sciences. 2017; 51 ():234-247.
Chicago/Turabian StyleKeunje Yoo; Tae Kwon Lee; Eun Joo Choi; Jihoon Yang; Sudheer Kumar Shukla; Sang-Il Hwang; Joonhong Park. 2017. "Molecular approaches for the detection and monitoring of microbial communities in bioaerosols: A review." Journal of Environmental Sciences 51, no. : 234-247.