This review highlights recent advances towards non-invasive and continuous glucose monitoring devices, with a particular focus placed on monitoring glucose concentrations in alternative physiological fluids to blood.

The bulk of the currently available biosensing techniques often require complex liquid handling, and thus suffer from problems associated with leakage and contamination. We demonstrate the use of an organic electrochemical transistor for detection of lactate (an essential analyte in physiological measurements of athlete performance) by integration of a room temperature ionic liquid in a gel-format, as a solid-state electrolyte.