Networks had an increasing impact on modern life since network cybersecurity has become an important research field. Several machine learning techniques have been developed to build network intrusion detection systems for correctly detecting unforeseen cyber-attacks at the network-level. For example, deep artificial neural network architectures have recently achieved state-of-the-art results. In this paper a novel deep neural network architecture is defined, in order to learn flexible and effective intrusion detection models, by combining an unsupervised stage for multi-channel feature learning with a supervised one exploiting feature dependencies on cross channels. The aim is to investigate whether class-specific features of the network flows could be learned and added to the original ones in order to increase the model accuracy. In particular, in the unsupervised stage, two autoencoders are separately learned on normal and attack flows, respectively. As the top layer in the decoder of these autoencoders reconstructs samples in the same space as the input one, they could be used to define two new feature vectors allowing the representation of each network flow as a multi-channel sample. In the supervised stage, a multi-channel parametric convolution is adopted, in order to learn the effect of each channel on the others. In particular, as the samples belong to two different distributions (normal and attack flows), the samples labelled as normal should be more similar to the representation reconstructed with the normal autoencoder than that of the attack one, and viceversa. This expected dependency will be exploited to better disentangle the differences between normal and attack flows. The proposed neural network architecture leads to better predictive accuracy when compared to competitive intrusion detection architectures on three benchmark datasets.

MicroRNAs (miRNAs) are a class of small non-coding RNAs which have been recognized as ubiquitous post-transcriptional regulators. The analysis of interactions between different miRNAs and their target genes is necessary for the understanding of miRNAs' role in the control of cell life and death. In this paper we propose a novel data mining algorithm, called HOCCLUS2, specifically designed to bicluster miRNAs and target messenger RNAs (mRNAs) on the basis of their experimentally-verified and/or predicted interactions. Indeed, existing biclustering approaches, typically used to analyze gene expression data, fail when applied to miRNA:mRNA interactions since they usually do not extract possibly overlapping biclusters (miRNAs and their target genes may have multiple roles), extract a huge amount of biclusters (difficult to browse and rank on the basis of their importance) and work on similarities of feature values (do not limit the analysis to reliable interactions).