This paper compares experimental results on the stabilization of clayey dredged material (DM) using quicklime (QL), hydrated lime (HL), portland cement (PC), and Class F fly ash (FA). The DM was a clay, high-plasticity soil, dredged from the US Army Corps of Engineers Port Arthur (USACEPA) facility along the Neches River located in Orange and Jefferson Counties, Texas. The soil consists of a large proportion of clay (66%), has high moisture limits (plasticity index: $\mathrm{PI}=52$ and liquid limit: $\mathrm{LL}=80$ ), and is characterized as a fat clay with silt. Physical properties of the untreated DM, such as unconfined compressive strength (UCS), consistency limits, and compaction behavior, were determined. Stabilizing reagents were mixed in various percentages by dry weight of DM. Results indicate that 12% QL, 6% HL, 6% PC, and 7.5% Class F FA by dry soil weight must be used to meet a minimum benchmark criterion of a PI value below 35, which was established based on Texas Department of Transportation (TxDOT) specifications. Standard compaction tests were carried out in accordance common standards with ASTM D698 to determine the optimum moisture content (OMC) for all mixtures. Stabilized mixtures were prepared at the corresponding OMC, and unconfined compressive tests were run according to common standards. Tests results were compared with the relevant literature, and a linear regression model was developed to predict the PI reduction as a function of initial PI, LL, and stabilizer type and content with good accuracy ($R^2=0.86$ ). Overall, tests showed that stabilization of clayey DM using lime products, PC, or FA significantly improved the DM physical properties, which could then potentially be used as a local fill construction material that is cost-effective and environmentally friendly and reduces the overall use of cement products.