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Dr. Mauro Colombo
Golgi Cenci Foundation

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0 Gerontology
0 cognitive aging
0 frailty
0 Rehabilitation medicine
0 Prevention medicine

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Short Biography

Born at Imperia (Liguria), married, 2 daughters. Scholarship for 2 years by the University of Pavia, attending the Specialization in Geriatrics & Gerontology (1981-3). Since 1983 operating by the Geriatric Institute "Camillo Golgi" [Abbiategrasso (Milan)]: person in charge for rehabilitative wards & for continuing medical education. Since 2011, in charge for the coordination of research for "Golgi Redaelli" ASP (Agency for Services to People). Retired 1-1-20; now volunteering at Golgi Cenci Foundation as researcher in Clinical Gerontology.

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Journal article
Published: 28 October 2020 in International Journal of Environmental Research and Public Health
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Older adults are less familiar with communication technology, which became essential to maintain social contacts during the COVID-19 lockdown. The present study aimed at exploring how older adults, previously trained for Social Networking Sites (SNSs) use, experienced the lockdown period. In the first two weeks of May 2020, telephone surveys were conducted with individuals aged 81–85 years and resident in Abbiategrasso (Milan), who previously participated in a study aimed at evaluating the impact of SNSs use on loneliness in old age (ClinicalTrials.gov, NCT04242628). We collected information on SNSs use, self-perceived loneliness, and social engagement with family and friends. Interviewed participants were stratified as trained (N = 60) and untrained (N = 70) for SNSs use, based on their attendance to group courses held the previous year as part of the main experimental study. The groups were comparable for sociodemographics and clinical features. Participants trained for SNSs use reported significantly higher usage of SNSs and reduced feeling of being left out. Compared to pre-lockdown levels, individuals trained for SNSs use showed a lighter reduction in social contacts. These findings support the utility of training older adults for SNSs use in order to improve their social inclusion, even in extreme conditions of self-isolation and perceived vulnerability.

ACS Style

Elena Rolandi; Roberta Vaccaro; Simona Abbondanza; Georgia Casanova; Laura Pettinato; Mauro Colombo; Antonio Guaita. Loneliness and Social Engagement in Older Adults Based in Lombardy during the COVID-19 Lockdown: The Long-Term Effects of a Course on Social Networking Sites Use. International Journal of Environmental Research and Public Health 2020, 17, 7912 .

AMA Style

Elena Rolandi, Roberta Vaccaro, Simona Abbondanza, Georgia Casanova, Laura Pettinato, Mauro Colombo, Antonio Guaita. Loneliness and Social Engagement in Older Adults Based in Lombardy during the COVID-19 Lockdown: The Long-Term Effects of a Course on Social Networking Sites Use. International Journal of Environmental Research and Public Health. 2020; 17 (21):7912.

Chicago/Turabian Style

Elena Rolandi; Roberta Vaccaro; Simona Abbondanza; Georgia Casanova; Laura Pettinato; Mauro Colombo; Antonio Guaita. 2020. "Loneliness and Social Engagement in Older Adults Based in Lombardy during the COVID-19 Lockdown: The Long-Term Effects of a Course on Social Networking Sites Use." International Journal of Environmental Research and Public Health 17, no. 21: 7912.

Journal article
Published: 05 August 2020 in Archives of Gerontology and Geriatrics
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Retrospective observational study aiming at testing whether different education levels in older adults are associated with the rehabilitation outcome. The study planned to cover all patients of over 65 rehabilitated from 2015 to 2017 at Golgi-Redaelli, a large government-funded rehabilitation Institute in Northern Italy comprising of three centers. Different administrative datasets were linked to investigate the factors associated with the functional outcome. The cohort resulted in 2,486 older adults for whom information on education and rehabilitation outcome was available. Rehabilitation outcome was measured with the Barthel Index testing the ability in basic activities of daily living and the Tinetti Performance Oriented Mobility Assessment measuring stability and walking. Multiple linear and logistic regression models were run controlling for rehabilitation setting and center of care, age, gender, cognitive functioning and comorbidity. Education resulted negatively associated with functional recovery. Patients with at least 8 years of education improved 2.24 point less in Barthel Index (out of100) and 0.70 points less in Tinetti Performance Oriented Mobility Assessment (out of 28) than the less educated patients. Results confirmed the importance of cognitive functioning in predicting rehabilitation outcome in older patients. Different mechanisms can explain an unexpected negative association between education and rehabilitation outcome, when possible inequalities in access to care are controlled for by study design (the cohort was admitted to a NHS-funded institute). Additional studies are needed to confirm our results and to test more specific hypotheses about the degree of effectiveness of rehabilitation across socio-economic groups.

ACS Style

Sara Zuccarino; Giovanni Fattore; Silvia Vitali; Gino Antronaco; Simona Frigerio; Mauro Colombo. The Association between Education and Rehabilitation Outcomes: a Population Retrospective Observational Study. Archives of Gerontology and Geriatrics 2020, 91, 104218 .

AMA Style

Sara Zuccarino, Giovanni Fattore, Silvia Vitali, Gino Antronaco, Simona Frigerio, Mauro Colombo. The Association between Education and Rehabilitation Outcomes: a Population Retrospective Observational Study. Archives of Gerontology and Geriatrics. 2020; 91 ():104218.

Chicago/Turabian Style

Sara Zuccarino; Giovanni Fattore; Silvia Vitali; Gino Antronaco; Simona Frigerio; Mauro Colombo. 2020. "The Association between Education and Rehabilitation Outcomes: a Population Retrospective Observational Study." Archives of Gerontology and Geriatrics 91, no. : 104218.

Short communication
Published: 11 April 2020 in Aging Clinical and Experimental Research
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The purposes of this retrospective study were to document the prevalence of serum C-reactive protein (CRP), a biomarker of inflammation, and its potential predictive value for Rehabilitation outcomes in post-acute elderly inpatients. The medical records of 304 elderly subjects admitted to our Rehabilitation Institute for any disease following an acute event were examined. High levels of CRP (> 0.5 mg/dl) were present in 100% of the subjects, and the value > 1.5 mg/dl (n = 86) predicted unfavourable outcomes (n = 28; 32.5% of the patients: death or transfer to other institutions). Among the patients with favourable outcomes (discharge home n = 255), 62.7% still exhibited severe disabilities. Pressure ulcers and low functional status also predicted unfavourable outcomes. The study highlights the need for future investigations into the possible reduction of CRP levels, after an intensive nutritional approach and combined physical interventions.

ACS Style

Roberto Aquilani; Ginetto Carlo Zuccarelli; Roberto Maestri; Carla Rutili; Mauro Colombo; Anna Maria Condino; Annalisa Barbieri; Alessandra Cecchetti; Simona Vanzati; Edi Bonazza; Franco Lafiandra; Daniela Buonocore; Manuela Verri; Maurizia Dossena; Federica Boschi. Inflammation, pressure ulcers and poor functional status predict negative rehabilitation outcomes in postacute geriatric patients. Aging Clinical and Experimental Research 2020, 33, 463 -467.

AMA Style

Roberto Aquilani, Ginetto Carlo Zuccarelli, Roberto Maestri, Carla Rutili, Mauro Colombo, Anna Maria Condino, Annalisa Barbieri, Alessandra Cecchetti, Simona Vanzati, Edi Bonazza, Franco Lafiandra, Daniela Buonocore, Manuela Verri, Maurizia Dossena, Federica Boschi. Inflammation, pressure ulcers and poor functional status predict negative rehabilitation outcomes in postacute geriatric patients. Aging Clinical and Experimental Research. 2020; 33 (2):463-467.

Chicago/Turabian Style

Roberto Aquilani; Ginetto Carlo Zuccarelli; Roberto Maestri; Carla Rutili; Mauro Colombo; Anna Maria Condino; Annalisa Barbieri; Alessandra Cecchetti; Simona Vanzati; Edi Bonazza; Franco Lafiandra; Daniela Buonocore; Manuela Verri; Maurizia Dossena; Federica Boschi. 2020. "Inflammation, pressure ulcers and poor functional status predict negative rehabilitation outcomes in postacute geriatric patients." Aging Clinical and Experimental Research 33, no. 2: 463-467.

Journal article
Published: 01 April 2020 in Journal of the American Medical Directors Association
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Few studies have analyzed factors associated with delirium subtypes. In this study, we investigate factors associated with subtypes of delirium only in patients with dementia to provide insights on the possible prevention and treatments. This is a cross-sectional study nested in the “Delirium Day” study, a nationwide Italian point-prevalence study. Older patients admitted to 205 acute and 92 rehabilitation hospital wards. Delirium was evaluated with the 4-AT and the motor subtypes with the Delirium Motor Subtype Scale. Dementia was defined by the presence of a documented diagnosis in the medical records and/or prescription of acetylcholinesterase inhibitors or memantine prior to admission. Of the 1057 patients with dementia, 35% had delirium, with 25.6% hyperactive, 33.1% hypoactive, 34.5% mixed, and 6.7% nonmotor subtype. There were higher odds of having venous catheters in the hypoactive (OR 1.82, 95% CI 1.18-2.81) and mixed type of delirium (OR 2.23, CI 1.43-3.46), whereas higher odds of urinary catheters in the hypoactive (OR 2.91, CI 1.92-4.39), hyperactive (OR 1.99, CI 1.23-3.21), and mixed types of delirium (OR 2.05, CI 1.36-3.07). We found higher odds of antipsychotics both in the hyperactive (OR 2.87, CI 1.81-4.54) and mixed subtype (OR 1.84, CI 1.24-2.75), whereas higher odds of antibiotics was present only in the mixed subtype (OR 1.91, CI 1.26-2.87). In patients with dementia, the mixed delirium subtype is the most prevalent followed by the hypoactive, hyperactive, and nonmotor subtype. Motor subtypes of delirium may be triggered by clinical factors, including the use of venous and urinary catheters, and the use of antipsychotics. Future studies are necessary to provide further insights on the possible pathophysiology of delirium in patients with dementia and to address the optimization of the management of potential risk factors.

ACS Style

Alessandro Morandi; Antonella Zambon; Simona G. Di Santo; Andrea Mazzone; Antonio Cherubini; Enrico Mossello; Mario Bo; Alessandra Marengoni; Giuseppe Bellelli; Vincenzo Rispoli; Alba Malara; Fausto Spadea; Serena Di Cello; Francesco Ceravolo; Francesco Fabiano; Giuseppe Chiaradia; Amedeo Gabriele; Peluso Lenino; Taristano Andrea; Vincenzo Settembrini; Domenico Capomolla; Antonella Citrino; Antonietta Scriva; Irene Bruno; Roberto Secchi; Eugenio De Martino; Roberto Muccinelli; Gerardo Lupi; Patrizio Paonessa; Andrea Fabbri; Maria Teresa Passuti; Sofia Castellari; Andrea Po; Guido Gaggioli; Massimo Varesi; Paolo Moneti; Sebastiano Capurso; Vincenzo Latini; Stefano Ghidotti; Francesco Riccardelli; Maurizio Macchi; Rosaria Rigo; Pascale Claudio; Bosio Angelo; Cerrato Flavio; Bardelli Benedetta; Stefano Boffelli; Angela Cassinadri; Simone Franzoni; Elena Spazzini; Daniela Andretto; Gabriele Tonini; Laura Andreani; Mirco Coralli; Antonio Balotta; Roberto Cancelliere; Giorgio Ballardini; Margherita Simoncelli; Annarita Mancini; Mara Strazzacapa; Stefano Fabio; Francesco De Filippi; Chiara Giudice; Cosimo Dentizzi; Margherita Azzini; Marco Cazzadori; Valeria Mastroeni; Paolo Bertassello; Helena Santana Claudia Benati; Elisa Nesta; Chiara Tobaldini; Fabio Guerini; Tambara Elena; Paolo Mombelloni; Fulvio Fontanini; Lassa Gabriella; Crosio Pizzorni; Martina Oliverio; Luciano Luca Del Grosso; Cristina Giavedoni; Giuliano Bidoli; Bruno Mazzei; Andrea Corsonello; Sergio Fusco; Silvio Vena; Tommaso De Vuono; Giorgio Maiuri; Fimognari Filippo Luca; Arone Andrea; Sgrò Giovanni; Nicolazzo Rossella; Eugenio Castegnaro; Salvatore De Rosa; Rossella Bazzano Sechi; Enrico Benvenuti; Ilaria Del Lungo; Sante Giardini; Chiara Giulietti; Di Bari Mauro; Barghini Eleonora; Paoli Martina; Fiordelli Irene; Barucci Riccardo; Sgrilli Federica; Del Lungo Ilaria; Erik Bertoletti; Ferdinando D'Amico; Francesco Caronzolo; Alessandro Grippa; Giuseppina Lombardo; Tiziana Pipicella; Saitta Antonino; Corica Francesco; Prestipino Giarritta Valeria; Larosa Daniela; Cucinotta Domenico; Basile Giorgio; Albert March; Maria Teresa Nitti; Alessandro Felici; Silvia Pavan; Fabrizio Piazzani; Alessandra Lunelli; Sergio Dimori; Alessandro Margotta; Tiziano Soglia; Demetrio Postacchini; Roberto Brunelli; Silvia Santini; Monia Francavilla; Ilenia Macchiati; Francesca Sorvillo; Cinzia Giuli; Patrizia Mecocci; Annalisa Longo; Francesco Perticone; Desireè Addesi; Paola Cerra Rosa; Giuseppe Bencardino; Tania Falbo; Nadia Grillo; Filice Marco; Flippo Mirella; Fausto Fantò; Gianluca Isaia; Stella Pezzilli; Daniele Bergamo; Elisabetta Furno; Sokol Rrodhe; Simonetta Lucarini; Babette Dijk; Francesca Dall'Acqua; Francesco Cappelletto; Donatella Calvani; Dimitri Becheri; Mottino Giuseppe; Mitidieri Costanza; Antonio Vito; Bartalucci Francesca; Lorenza Magherini; Malin Novella; Boni Franca; Paoli Martina Lucia Gambardella; Carlo Valente; Bracali Ilaria; Foschini Alice; Paola Porrino; Giacomo Ceci; Bottignole Giuliana; Tibaldi Michela; Coppo Eleonora; Evaristo Ettore; Cinzia Camellini; Adriana Servello; Alessandro Grassi; Renzo Rozzini; Sara Tironi; Maria Grazia Grassi; Elio Troisi; Caltagirone Carlo; Di Santo Simona Gabriella; Franchini Flaminia; Ratto Federica; Pavoni Beatrice; Toniolo Sofia; Anna Gabutto; Loredana Quazzo; Annalisa Rosatello; Domenico Suraci; Benedetta Tagliabue; Chiara Perrone; Lucia Ferrara; Alberto Castagna; Maria Luisa Tremolada; Castoldi Giuseppe; Barbero Stefano; Oltramonti Davide; Simonetta Piano; Gaetano Serviddio; Aurelio Lo Buglio; Tiziana Gurrera; Valeria Merlo; Carla Rovai; Antonino Maria Cotroneo; Rosaria Carlucci; Anna Abbaldo; Fabio Monzani; Ahmad Amedeo Qasem; Giacomo Bini; Silvia Tafuto; Giovanni Galli; Amalia Cecilia Bruni; Giovanna Mancuso; Gerardo Mancuso; Daniela Calipari; De Luca Giuseppe Massimiliano; Bruno Bernardini; Carla Corsini; Ciccarelli Michele; Dal Farra Sara; AnnaChiara Cagnin; Federica Fragiacomo; Sara Pompanin; Amodio Piero; Cagnin Marco; Amedeo Zurlo; Gianluca Guerra; Marco Pala; Luca Menozzi; Chiara Delli Gatti; Stefania Magon; Manfredini Roberto; De Giorgi Alfredo; Fabbian Fabio; Tiseo Ruana; Misurati Elisa; Boari Benedetta; Molino Christian; Pala Marco; Gallerani Massimo; Vincenzo Di Francesco; Silvia Faccioli; Luca Pellizzari; Fontana Giorgia; Giuseppe Barbagallo; Maria Lia Lunardelli; Emilio Martini; Eleonora Ferrari; Maria Macchiarulo; Maria Corneli; Monica Bacci; Giuseppe Battaglia; Luigi Anastasio; Mario Sostene Lo Storto; Chiara Seresin; Matteo Simonato; Michele Loreggian; Fausta Cestonaro; Mario Durando; Raffaele Latella; Marta Mazzoleni; Giuseppe Russo; Martino Ponte; Alessandro Valchera; Giuseppe Salustri; Donatella Petritola; Alfredo Costa; Elena Sinforiani; Matteo Ramusino Cotta; Renato Nicola Pizio; Alberto Cester; Marino Formilan; Bonometto Pietro; Pasqualina Carbone; Ilaria Cazzaniga; Ildebrando Appollonio; Diletta Cereda; Andrea Stabile; Rubjona Xhani; Roberto Acampora; Lucio Tremolizzo; Pieruzzi Federico; Ciaccio Antonio; Pontecorvi Valerio; Burti Cesare; Mokini Zhirajr; Vitale Giovanni; Amigoni Maria; Sparacino Mariaelena; Edo Bottacchi; Elisabetta Bucciantini; Marco Di Giovanni; Fabrizio Franchi; Lucio Lucchetti; Claudio Mariani; Giulia Grande; Piero Rapazzini; Mauri Marco; Giuseppe Ro. Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia. Journal of the American Medical Directors Association 2020, 21, 486 -492.e7.

AMA Style

Alessandro Morandi, Antonella Zambon, Simona G. Di Santo, Andrea Mazzone, Antonio Cherubini, Enrico Mossello, Mario Bo, Alessandra Marengoni, Giuseppe Bellelli, Vincenzo Rispoli, Alba Malara, Fausto Spadea, Serena Di Cello, Francesco Ceravolo, Francesco Fabiano, Giuseppe Chiaradia, Amedeo Gabriele, Peluso Lenino, Taristano Andrea, Vincenzo Settembrini, Domenico Capomolla, Antonella Citrino, Antonietta Scriva, Irene Bruno, Roberto Secchi, Eugenio De Martino, Roberto Muccinelli, Gerardo Lupi, Patrizio Paonessa, Andrea Fabbri, Maria Teresa Passuti, Sofia Castellari, Andrea Po, Guido Gaggioli, Massimo Varesi, Paolo Moneti, Sebastiano Capurso, Vincenzo Latini, Stefano Ghidotti, Francesco Riccardelli, Maurizio Macchi, Rosaria Rigo, Pascale Claudio, Bosio Angelo, Cerrato Flavio, Bardelli Benedetta, Stefano Boffelli, Angela Cassinadri, Simone Franzoni, Elena Spazzini, Daniela Andretto, Gabriele Tonini, Laura Andreani, Mirco Coralli, Antonio Balotta, Roberto Cancelliere, Giorgio Ballardini, Margherita Simoncelli, Annarita Mancini, Mara Strazzacapa, Stefano Fabio, Francesco De Filippi, Chiara Giudice, Cosimo Dentizzi, Margherita Azzini, Marco Cazzadori, Valeria Mastroeni, Paolo Bertassello, Helena Santana Claudia Benati, Elisa Nesta, Chiara Tobaldini, Fabio Guerini, Tambara Elena, Paolo Mombelloni, Fulvio Fontanini, Lassa Gabriella, Crosio Pizzorni, Martina Oliverio, Luciano Luca Del Grosso, Cristina Giavedoni, Giuliano Bidoli, Bruno Mazzei, Andrea Corsonello, Sergio Fusco, Silvio Vena, Tommaso De Vuono, Giorgio Maiuri, Fimognari Filippo Luca, Arone Andrea, Sgrò Giovanni, Nicolazzo Rossella, Eugenio Castegnaro, Salvatore De Rosa, Rossella Bazzano Sechi, Enrico Benvenuti, Ilaria Del Lungo, Sante Giardini, Chiara Giulietti, Di Bari Mauro, Barghini Eleonora, Paoli Martina, Fiordelli Irene, Barucci Riccardo, Sgrilli Federica, Del Lungo Ilaria, Erik Bertoletti, Ferdinando D'Amico, Francesco Caronzolo, Alessandro Grippa, Giuseppina Lombardo, Tiziana Pipicella, Saitta Antonino, Corica Francesco, Prestipino Giarritta Valeria, Larosa Daniela, Cucinotta Domenico, Basile Giorgio, Albert March, Maria Teresa Nitti, Alessandro Felici, Silvia Pavan, Fabrizio Piazzani, Alessandra Lunelli, Sergio Dimori, Alessandro Margotta, Tiziano Soglia, Demetrio Postacchini, Roberto Brunelli, Silvia Santini, Monia Francavilla, Ilenia Macchiati, Francesca Sorvillo, Cinzia Giuli, Patrizia Mecocci, Annalisa Longo, Francesco Perticone, Desireè Addesi, Paola Cerra Rosa, Giuseppe Bencardino, Tania Falbo, Nadia Grillo, Filice Marco, Flippo Mirella, Fausto Fantò, Gianluca Isaia, Stella Pezzilli, Daniele Bergamo, Elisabetta Furno, Sokol Rrodhe, Simonetta Lucarini, Babette Dijk, Francesca Dall'Acqua, Francesco Cappelletto, Donatella Calvani, Dimitri Becheri, Mottino Giuseppe, Mitidieri Costanza, Antonio Vito, Bartalucci Francesca, Lorenza Magherini, Malin Novella, Boni Franca, Paoli Martina Lucia Gambardella, Carlo Valente, Bracali Ilaria, Foschini Alice, Paola Porrino, Giacomo Ceci, Bottignole Giuliana, Tibaldi Michela, Coppo Eleonora, Evaristo Ettore, Cinzia Camellini, Adriana Servello, Alessandro Grassi, Renzo Rozzini, Sara Tironi, Maria Grazia Grassi, Elio Troisi, Caltagirone Carlo, Di Santo Simona Gabriella, Franchini Flaminia, Ratto Federica, Pavoni Beatrice, Toniolo Sofia, Anna Gabutto, Loredana Quazzo, Annalisa Rosatello, Domenico Suraci, Benedetta Tagliabue, Chiara Perrone, Lucia Ferrara, Alberto Castagna, Maria Luisa Tremolada, Castoldi Giuseppe, Barbero Stefano, Oltramonti Davide, Simonetta Piano, Gaetano Serviddio, Aurelio Lo Buglio, Tiziana Gurrera, Valeria Merlo, Carla Rovai, Antonino Maria Cotroneo, Rosaria Carlucci, Anna Abbaldo, Fabio Monzani, Ahmad Amedeo Qasem, Giacomo Bini, Silvia Tafuto, Giovanni Galli, Amalia Cecilia Bruni, Giovanna Mancuso, Gerardo Mancuso, Daniela Calipari, De Luca Giuseppe Massimiliano, Bruno Bernardini, Carla Corsini, Ciccarelli Michele, Dal Farra Sara, AnnaChiara Cagnin, Federica Fragiacomo, Sara Pompanin, Amodio Piero, Cagnin Marco, Amedeo Zurlo, Gianluca Guerra, Marco Pala, Luca Menozzi, Chiara Delli Gatti, Stefania Magon, Manfredini Roberto, De Giorgi Alfredo, Fabbian Fabio, Tiseo Ruana, Misurati Elisa, Boari Benedetta, Molino Christian, Pala Marco, Gallerani Massimo, Vincenzo Di Francesco, Silvia Faccioli, Luca Pellizzari, Fontana Giorgia, Giuseppe Barbagallo, Maria Lia Lunardelli, Emilio Martini, Eleonora Ferrari, Maria Macchiarulo, Maria Corneli, Monica Bacci, Giuseppe Battaglia, Luigi Anastasio, Mario Sostene Lo Storto, Chiara Seresin, Matteo Simonato, Michele Loreggian, Fausta Cestonaro, Mario Durando, Raffaele Latella, Marta Mazzoleni, Giuseppe Russo, Martino Ponte, Alessandro Valchera, Giuseppe Salustri, Donatella Petritola, Alfredo Costa, Elena Sinforiani, Matteo Ramusino Cotta, Renato Nicola Pizio, Alberto Cester, Marino Formilan, Bonometto Pietro, Pasqualina Carbone, Ilaria Cazzaniga, Ildebrando Appollonio, Diletta Cereda, Andrea Stabile, Rubjona Xhani, Roberto Acampora, Lucio Tremolizzo, Pieruzzi Federico, Ciaccio Antonio, Pontecorvi Valerio, Burti Cesare, Mokini Zhirajr, Vitale Giovanni, Amigoni Maria, Sparacino Mariaelena, Edo Bottacchi, Elisabetta Bucciantini, Marco Di Giovanni, Fabrizio Franchi, Lucio Lucchetti, Claudio Mariani, Giulia Grande, Piero Rapazzini, Mauri Marco, Giuseppe Ro. Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia. Journal of the American Medical Directors Association. 2020; 21 (4):486-492.e7.

Chicago/Turabian Style

Alessandro Morandi; Antonella Zambon; Simona G. Di Santo; Andrea Mazzone; Antonio Cherubini; Enrico Mossello; Mario Bo; Alessandra Marengoni; Giuseppe Bellelli; Vincenzo Rispoli; Alba Malara; Fausto Spadea; Serena Di Cello; Francesco Ceravolo; Francesco Fabiano; Giuseppe Chiaradia; Amedeo Gabriele; Peluso Lenino; Taristano Andrea; Vincenzo Settembrini; Domenico Capomolla; Antonella Citrino; Antonietta Scriva; Irene Bruno; Roberto Secchi; Eugenio De Martino; Roberto Muccinelli; Gerardo Lupi; Patrizio Paonessa; Andrea Fabbri; Maria Teresa Passuti; Sofia Castellari; Andrea Po; Guido Gaggioli; Massimo Varesi; Paolo Moneti; Sebastiano Capurso; Vincenzo Latini; Stefano Ghidotti; Francesco Riccardelli; Maurizio Macchi; Rosaria Rigo; Pascale Claudio; Bosio Angelo; Cerrato Flavio; Bardelli Benedetta; Stefano Boffelli; Angela Cassinadri; Simone Franzoni; Elena Spazzini; Daniela Andretto; Gabriele Tonini; Laura Andreani; Mirco Coralli; Antonio Balotta; Roberto Cancelliere; Giorgio Ballardini; Margherita Simoncelli; Annarita Mancini; Mara Strazzacapa; Stefano Fabio; Francesco De Filippi; Chiara Giudice; Cosimo Dentizzi; Margherita Azzini; Marco Cazzadori; Valeria Mastroeni; Paolo Bertassello; Helena Santana Claudia Benati; Elisa Nesta; Chiara Tobaldini; Fabio Guerini; Tambara Elena; Paolo Mombelloni; Fulvio Fontanini; Lassa Gabriella; Crosio Pizzorni; Martina Oliverio; Luciano Luca Del Grosso; Cristina Giavedoni; Giuliano Bidoli; Bruno Mazzei; Andrea Corsonello; Sergio Fusco; Silvio Vena; Tommaso De Vuono; Giorgio Maiuri; Fimognari Filippo Luca; Arone Andrea; Sgrò Giovanni; Nicolazzo Rossella; Eugenio Castegnaro; Salvatore De Rosa; Rossella Bazzano Sechi; Enrico Benvenuti; Ilaria Del Lungo; Sante Giardini; Chiara Giulietti; Di Bari Mauro; Barghini Eleonora; Paoli Martina; Fiordelli Irene; Barucci Riccardo; Sgrilli Federica; Del Lungo Ilaria; Erik Bertoletti; Ferdinando D'Amico; Francesco Caronzolo; Alessandro Grippa; Giuseppina Lombardo; Tiziana Pipicella; Saitta Antonino; Corica Francesco; Prestipino Giarritta Valeria; Larosa Daniela; Cucinotta Domenico; Basile Giorgio; Albert March; Maria Teresa Nitti; Alessandro Felici; Silvia Pavan; Fabrizio Piazzani; Alessandra Lunelli; Sergio Dimori; Alessandro Margotta; Tiziano Soglia; Demetrio Postacchini; Roberto Brunelli; Silvia Santini; Monia Francavilla; Ilenia Macchiati; Francesca Sorvillo; Cinzia Giuli; Patrizia Mecocci; Annalisa Longo; Francesco Perticone; Desireè Addesi; Paola Cerra Rosa; Giuseppe Bencardino; Tania Falbo; Nadia Grillo; Filice Marco; Flippo Mirella; Fausto Fantò; Gianluca Isaia; Stella Pezzilli; Daniele Bergamo; Elisabetta Furno; Sokol Rrodhe; Simonetta Lucarini; Babette Dijk; Francesca Dall'Acqua; Francesco Cappelletto; Donatella Calvani; Dimitri Becheri; Mottino Giuseppe; Mitidieri Costanza; Antonio Vito; Bartalucci Francesca; Lorenza Magherini; Malin Novella; Boni Franca; Paoli Martina Lucia Gambardella; Carlo Valente; Bracali Ilaria; Foschini Alice; Paola Porrino; Giacomo Ceci; Bottignole Giuliana; Tibaldi Michela; Coppo Eleonora; Evaristo Ettore; Cinzia Camellini; Adriana Servello; Alessandro Grassi; Renzo Rozzini; Sara Tironi; Maria Grazia Grassi; Elio Troisi; Caltagirone Carlo; Di Santo Simona Gabriella; Franchini Flaminia; Ratto Federica; Pavoni Beatrice; Toniolo Sofia; Anna Gabutto; Loredana Quazzo; Annalisa Rosatello; Domenico Suraci; Benedetta Tagliabue; Chiara Perrone; Lucia Ferrara; Alberto Castagna; Maria Luisa Tremolada; Castoldi Giuseppe; Barbero Stefano; Oltramonti Davide; Simonetta Piano; Gaetano Serviddio; Aurelio Lo Buglio; Tiziana Gurrera; Valeria Merlo; Carla Rovai; Antonino Maria Cotroneo; Rosaria Carlucci; Anna Abbaldo; Fabio Monzani; Ahmad Amedeo Qasem; Giacomo Bini; Silvia Tafuto; Giovanni Galli; Amalia Cecilia Bruni; Giovanna Mancuso; Gerardo Mancuso; Daniela Calipari; De Luca Giuseppe Massimiliano; Bruno Bernardini; Carla Corsini; Ciccarelli Michele; Dal Farra Sara; AnnaChiara Cagnin; Federica Fragiacomo; Sara Pompanin; Amodio Piero; Cagnin Marco; Amedeo Zurlo; Gianluca Guerra; Marco Pala; Luca Menozzi; Chiara Delli Gatti; Stefania Magon; Manfredini Roberto; De Giorgi Alfredo; Fabbian Fabio; Tiseo Ruana; Misurati Elisa; Boari Benedetta; Molino Christian; Pala Marco; Gallerani Massimo; Vincenzo Di Francesco; Silvia Faccioli; Luca Pellizzari; Fontana Giorgia; Giuseppe Barbagallo; Maria Lia Lunardelli; Emilio Martini; Eleonora Ferrari; Maria Macchiarulo; Maria Corneli; Monica Bacci; Giuseppe Battaglia; Luigi Anastasio; Mario Sostene Lo Storto; Chiara Seresin; Matteo Simonato; Michele Loreggian; Fausta Cestonaro; Mario Durando; Raffaele Latella; Marta Mazzoleni; Giuseppe Russo; Martino Ponte; Alessandro Valchera; Giuseppe Salustri; Donatella Petritola; Alfredo Costa; Elena Sinforiani; Matteo Ramusino Cotta; Renato Nicola Pizio; Alberto Cester; Marino Formilan; Bonometto Pietro; Pasqualina Carbone; Ilaria Cazzaniga; Ildebrando Appollonio; Diletta Cereda; Andrea Stabile; Rubjona Xhani; Roberto Acampora; Lucio Tremolizzo; Pieruzzi Federico; Ciaccio Antonio; Pontecorvi Valerio; Burti Cesare; Mokini Zhirajr; Vitale Giovanni; Amigoni Maria; Sparacino Mariaelena; Edo Bottacchi; Elisabetta Bucciantini; Marco Di Giovanni; Fabrizio Franchi; Lucio Lucchetti; Claudio Mariani; Giulia Grande; Piero Rapazzini; Mauri Marco; Giuseppe Ro. 2020. "Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia." Journal of the American Medical Directors Association 21, no. 4: 486-492.e7.

Journal article
Published: 01 January 2020 in Health
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Background: Awareness of hearing disability in the elderly has adverse cognitive and functional consequences over time, in a longitudinal population-based study. Aim: To analyze the hypothesis that over time old people aware of hearing disability make less use of technology and lose more instrumental activities of daily living than peers with other self-reported hearing conditions. Methods: We analyzed 1171 healthy participants in the longitudinal population-based InveCe.Ab study. The consistency between self-reported hearing loss with clinician-evaluated hearing status (Whispered Voice Test; WVT), was categorized by consistency as: unaware of hearing loss (UHL), aware of hearing loss (AHL), only subjective hearing loss (OSHL), without hearing loss (noHL). Results: At baseline (2010), hearing loss was found in 159 [13.6% (95% CI: 11.7 - 15.7)] of the participants [28 = 17.6% (95% CI: 12.0 - 24.4) AHL; 131 = 82.4% (95% CI: 75.6 - 88) UHL], while 23 [2.3% (95% CI: 1.4 - 3.4)] of the subjects with normal WVT had OSHL. Mobile phone usage was significantly associated with different consistency categories (p i.e. executive, memory and visuo-spatial) were independently associated with maintaining mobile phone usage and instrumental activities of daily living. Conclusion: Self-reported hearing disability is linked to subsequent loss of mobile phone usage and functional dependency. As cognitive performances independently influence technology usage and functional impairment, targeted preventive interventions should address functional impact of perceived hearing loss, but also encourage social participation and improve mobile phone usage. Trial registration: ClinicalTrials.gov, NCT01345110; registered on April 29, 2011.

ACS Style

Roberta Vaccaro; Mauro Colombo; Simona Abbondanza; Elena Rolandi; Laura Pettinato; Antonio Guaita. Technology Usage among Elderly with Self-Reported Hearing Disability: Results from InveCe.Ab. Health 2020, 12, 353 -367.

AMA Style

Roberta Vaccaro, Mauro Colombo, Simona Abbondanza, Elena Rolandi, Laura Pettinato, Antonio Guaita. Technology Usage among Elderly with Self-Reported Hearing Disability: Results from InveCe.Ab. Health. 2020; 12 (04):353-367.

Chicago/Turabian Style

Roberta Vaccaro; Mauro Colombo; Simona Abbondanza; Elena Rolandi; Laura Pettinato; Antonio Guaita. 2020. "Technology Usage among Elderly with Self-Reported Hearing Disability: Results from InveCe.Ab." Health 12, no. 04: 353-367.

Journal article
Published: 01 July 2019 in Alzheimer's & Dementia
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Roberta Vaccaro; Daniele Zaccaria; Mauro Colombo; Elena Rolandi; Simona Abbondanza; Antonio Guaita. P1-512: INCIDENCE OF MILD NEUROCOGNITIVE DISORDERS AND DEMENTIA IN ELDERLY ITALIANS WITH SELF-REPORTED HEARING DISABILITY: RESULTS FROM THE INVECE.AB STUDY. Alzheimer's & Dementia 2019, 15, P465 -P465.

AMA Style

Roberta Vaccaro, Daniele Zaccaria, Mauro Colombo, Elena Rolandi, Simona Abbondanza, Antonio Guaita. P1-512: INCIDENCE OF MILD NEUROCOGNITIVE DISORDERS AND DEMENTIA IN ELDERLY ITALIANS WITH SELF-REPORTED HEARING DISABILITY: RESULTS FROM THE INVECE.AB STUDY. Alzheimer's & Dementia. 2019; 15 (7):P465-P465.

Chicago/Turabian Style

Roberta Vaccaro; Daniele Zaccaria; Mauro Colombo; Elena Rolandi; Simona Abbondanza; Antonio Guaita. 2019. "P1-512: INCIDENCE OF MILD NEUROCOGNITIVE DISORDERS AND DEMENTIA IN ELDERLY ITALIANS WITH SELF-REPORTED HEARING DISABILITY: RESULTS FROM THE INVECE.AB STUDY." Alzheimer's & Dementia 15, no. 7: P465-P465.

Journal article
Published: 01 March 2019 in Maturitas
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Hearing loss is a common chronic condition in elderly people. The prevalence of disabling hearing loss among the elderly worldwide is 33% and in Italy ranges from 0.6% (profound hearing loss) to 39% (mild hearing loss). We investigated the relationship between self-reported hearing disability and clinician-evaluated hearing status, and its longitudinal consequences in relation to cognitive impairment and functional decline. We hypothesised that subjects who report that they have a hearing disability have a worse functional and cognitive profile than people who do not report having a hearing disability. We analysed 1171 participants in the InveCe.Ab study, a longitudinal population-based study. We evaluated whether self-reported hearing disability was consistent with clinician-evaluated hearing status (using the Whispered Voice Test; WVT), categorizing this variable as: unaware of hearing loss (UHL), aware of hearing loss (AHL), only subjective hearing loss (OSHL), without hearing loss (noHL). We also examined its relationship with various population characteristics, and its long-term effects on functional and cognitive performance and depressive symptoms. At baseline, hearing loss was found in 13.6% (95% CI: 11.7-15.7) of the participants [17.6% (95% CI: 12.0-24.4) AHL; 82.4% (95% CI: 75.6-88) UHL], while 2.3% (95% CI: 1.4-3.4) of the subjects with normal WVT hearing status had OSHL. Male gender, age, functional and cognitive performance, and depressive symptoms were associated with consistency between self-reported hearing disability and WVT hearing status. Longitudinal analysis revealed worsening functional performance and selective attention, global cognitive deterioration, and depressive symptoms in the AHL group. Our results showed that awareness of hearing disability in the elderly has adverse cognitive and functional consequences over time. When clinicians inform those who are unaware of their hearing problems, they should arrange for prompt referral not only for audiometric evaluation but also for counselling in order to prevent a negative impact of awareness of hearing loss.

ACS Style

Roberta Vaccaro; Daniele Zaccaria; Mauro Colombo; Simona Abbondanza; Antonio Guaita. Adverse effect of self-reported hearing disability in elderly Italians: Results from the InveCe.Ab study. Maturitas 2019, 121, 35 -40.

AMA Style

Roberta Vaccaro, Daniele Zaccaria, Mauro Colombo, Simona Abbondanza, Antonio Guaita. Adverse effect of self-reported hearing disability in elderly Italians: Results from the InveCe.Ab study. Maturitas. 2019; 121 ():35-40.

Chicago/Turabian Style

Roberta Vaccaro; Daniele Zaccaria; Mauro Colombo; Simona Abbondanza; Antonio Guaita. 2019. "Adverse effect of self-reported hearing disability in elderly Italians: Results from the InveCe.Ab study." Maturitas 121, no. : 35-40.

Research article
Published: 14 March 2017 in BioMed Research International
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Estimates of depressive disorders in the elderly vary depending on how cases are defined. We estimated the prevalence of subthreshold depression (SD) and clinically significant depression (D) in a population of 70–74-year-olds. We also looked for associations with sociodemographic factors and perceptions of self. Participants underwent a multidimensional assessment (social, medical, and neuropsychological). The estimated prevalence of SD was 15.71% (95% CI: 13.70–17.72), while that of D was 5.58% (95% CI: 4.31–6.85). Multinomial logistic regression analysis revealed that female gender and dissatisfaction with family relationships were related to SD and D. A self-perception of physical age as older than actual age (but not comorbidity) and greater self-perceived stress caused by negative life events both increased the probability of SD. The likelihood of D was decreased in those who perceived their own health as good, whereas a self-perception of mental age as older than actual age and dissatisfaction with relationships with friends were both significantly associated with D. Both SD and D emerged as key problems in our population. Female gender and self-perceptions of various characteristics, which can be explored through simple questions, are associated with late-life depression in elderly people independently of their actual physical condition and other characteristics.

ACS Style

Roberta Vaccaro; Paola Borrelli; Simona Abbondanza; Annalisa Davin; Letizia Polito; Mauro Colombo; Silvia Francesca Vitali; Simona Villani; Antonio Guaita. Subthreshold Depression and Clinically Significant Depression in an Italian Population of 70–74-Year-Olds: Prevalence and Association with Perceptions of Self. BioMed Research International 2017, 2017, 1 -8.

AMA Style

Roberta Vaccaro, Paola Borrelli, Simona Abbondanza, Annalisa Davin, Letizia Polito, Mauro Colombo, Silvia Francesca Vitali, Simona Villani, Antonio Guaita. Subthreshold Depression and Clinically Significant Depression in an Italian Population of 70–74-Year-Olds: Prevalence and Association with Perceptions of Self. BioMed Research International. 2017; 2017 ():1-8.

Chicago/Turabian Style

Roberta Vaccaro; Paola Borrelli; Simona Abbondanza; Annalisa Davin; Letizia Polito; Mauro Colombo; Silvia Francesca Vitali; Simona Villani; Antonio Guaita. 2017. "Subthreshold Depression and Clinically Significant Depression in an Italian Population of 70–74-Year-Olds: Prevalence and Association with Perceptions of Self." BioMed Research International 2017, no. : 1-8.

Journal article
Published: 01 January 2017 in Health
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Aim: Person-centered care is a core issue in rehabilitation; the study aims at: 1) enquiring the outcome expectations of patients in a geriatric rehabilitation ward; 2) matching outcome expectations with actual outcomes. Methods: Expectations of 186 patients [79.4 (8.7) years, 70% females] analyzed through a questionnaire. 80.6% of patients were discharged home; functional recovery = 17.7 (22) points in Barthel Index total score, and 5 (4.2) points in Barthel Index walking subscore; also conditions with nursing needs improved significantly. Results: Patients’ expectations were coded as: functional (31.4%), overall (29.6%), and clinical improvement (21.5%), discharge home (7%); no answers or explicit lack of expectations (7.5%). Walking ability recovery differed according to outcome expectations. Highest improvements were achieved by patients wishing clinical improvement, followed by those expecting functional or overall improvement (5 points) [p = 0.009 (Welch)/p = 0.041 (Brown- Forsythe)]; worst improvement in walking ability (2.8 points) were got by patients faulting or declaring explicit failure of expectations. Conditions with nursing needs improved most in those expecting clinical improvements [p = 0.029 (Brown-Forsythe)], and less in case of expectation default. No further matching was found. Conclusions: Improvement in actual outcomes matched expected improvements in two circumstances: recovery in walking ability and in conditions with nursing needs. The high yield of different favorable outcomes may have masked the statistical significance for correspondence between actual and expected results. Special attention is worthy towards patients short of expectations, as their actual outcomes result poorer.

ACS Style

Mauro Colombo; Carla Facchini; Achim Rusu; Eleonora Marelli; Giuseppe Procino; Rosella Capuano; Cristina Miramonti; Antonio Guaita. Patients’ Expectations in a Geriatric Rehabilitation Ward: Matching with Actual Outcomes. Health 2017, 09, 1597 -1604.

AMA Style

Mauro Colombo, Carla Facchini, Achim Rusu, Eleonora Marelli, Giuseppe Procino, Rosella Capuano, Cristina Miramonti, Antonio Guaita. Patients’ Expectations in a Geriatric Rehabilitation Ward: Matching with Actual Outcomes. Health. 2017; 09 (11):1597-1604.

Chicago/Turabian Style

Mauro Colombo; Carla Facchini; Achim Rusu; Eleonora Marelli; Giuseppe Procino; Rosella Capuano; Cristina Miramonti; Antonio Guaita. 2017. "Patients’ Expectations in a Geriatric Rehabilitation Ward: Matching with Actual Outcomes." Health 09, no. 11: 1597-1604.

Journal article
Published: 01 March 2015 in Archives of Gerontology and Geriatrics
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The age-specific prevalence rates of dementia vary widely. Studies focusing on specific age groups are needed to provide reliable estimates for healthcare providers and policy makers. We estimated the prevalence of dementia, dementia subtypes and cognitive impairment in "InveCe.Ab" (ClinicalTrials.gov, NCT01345110), a single-step multidimensional population-based study of 70-74-year olds living in Abbiategrasso (Milan, Italy). We also looked for associations with socio-demographic factors and the presence of the apolipoprotein E-ɛ4 allele. The overall dementia prevalence was 3% (95%CI: 2.1-4.1%) [Alzheimer's disease (AD): 1.2% (95%CI 0.6-1.9%); vascular dementia (VD): 1.4% (95%CI: 0.8-2.2%)]. Being single was found to be a risk factor for vascular dementia; subjects born in southern Italy were shown to be at greater risk both of overall dementia and of vascular dementia. The prevalence of cognitive impairment, with or without subjective cognitive complaints (cognitive impairment, no dementia, CIND) was 7.8% (95%CI: 6.4-9.4%). As regards the CIND subgroups, the prevalence of subjects with subjective cognitive complaints (mild cognitive impairment, MCI) was 5.0% (95%CI 3.9-6.3%), while the prevalence of those without MCI (CIND-other) was 2.8% (95%CI: 1.9-3.8). The males had a higher risk of MCI and CIND-other; the older subjects were more likely to have MCI, and those born in north-eastern Italy to have CIND-other. The prevalence of AD was higher among the apolipoprotein E-ɛ4 carriers. Our data highlight the importance of dementia and cognitive impairment in the transitional period from adulthood to old age, and reveal the presence of different associations with socio-demographic and genetic factors.

ACS Style

Antonio Guaita; Roberta Vaccaro; Annalisa Davin; Mauro Colombo; Silvia Francesca Vitali; Letizia Polito; Simona Abbondanza; Eleonora Valle; Gianluigi Forloni; Virginia Valeria Ferretti; Simona Villani. Influence of socio-demographic features and apolipoprotein E epsilon 4 expression on the prevalence of dementia and cognitive impairment in a population of 70–74-year olds: The InveCe.Ab study. Archives of Gerontology and Geriatrics 2015, 60, 334 -343.

AMA Style

Antonio Guaita, Roberta Vaccaro, Annalisa Davin, Mauro Colombo, Silvia Francesca Vitali, Letizia Polito, Simona Abbondanza, Eleonora Valle, Gianluigi Forloni, Virginia Valeria Ferretti, Simona Villani. Influence of socio-demographic features and apolipoprotein E epsilon 4 expression on the prevalence of dementia and cognitive impairment in a population of 70–74-year olds: The InveCe.Ab study. Archives of Gerontology and Geriatrics. 2015; 60 (2):334-343.

Chicago/Turabian Style

Antonio Guaita; Roberta Vaccaro; Annalisa Davin; Mauro Colombo; Silvia Francesca Vitali; Letizia Polito; Simona Abbondanza; Eleonora Valle; Gianluigi Forloni; Virginia Valeria Ferretti; Simona Villani. 2015. "Influence of socio-demographic features and apolipoprotein E epsilon 4 expression on the prevalence of dementia and cognitive impairment in a population of 70–74-year olds: The InveCe.Ab study." Archives of Gerontology and Geriatrics 60, no. 2: 334-343.

Journal article
Published: 01 January 2015 in Health
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Aim: Hip fracture implies severe problems to older people; special concerns regard persons with dementia, due either to cognitive impairment, or to behavioral and psychic symptoms. This study illustrates rehabilitative outcomes of these patients discharged by a special care unit ruled by “GentleCare” principles. Method: 54 patients [89% females, aged 82.3 years (range 66 - 94)] followed a post-surgery rehabilitative program carried out by a physiotherapist and an occupational therapist, supported by a psychologist. The multidimensional assessment consisted of cognition evaluation (Mini Mental State Examination, Clinical Dementia Rating, Global Deterioration Scale), functional evaluation (Barthel Index, Tinetti Gait and Balance, Bedford Alzheimer Nursing Severity scale), behavioral evaluation (UCLA Neuropsychiatric Inventory) and comorbidity evaluation (Cumulative Illness Rating Scale). Results: All parameters improved, including the 5 most frequent behavioral and psychic symptoms that usually preclude admission in ordinary rehabilitation units. 24% of improvement in Barthel Index total score was explained by agitation and apathy at discharge, in a multiple linear regression model: better functional levels corresponded to smoother behavioral problems. Most patients improved; 70.5% of them were discharged to home. Conclusion: A prosthetic approach enables valuable results in the rehabilitation of severely demented patients with hip fracture also in presence of behavioral symptoms.

ACS Style

Mauro Colombo; Silvia Vitali; Chiara Cutaia; Eleonora Marelli; Antonio Guaita. Rehabilitative Outcomes after Hip Fracture in a Special Care Unit for Persons with Dementia and Behavioral and Psychotic Symptoms. Health 2015, 07, 1175 -1182.

AMA Style

Mauro Colombo, Silvia Vitali, Chiara Cutaia, Eleonora Marelli, Antonio Guaita. Rehabilitative Outcomes after Hip Fracture in a Special Care Unit for Persons with Dementia and Behavioral and Psychotic Symptoms. Health. 2015; 07 (09):1175-1182.

Chicago/Turabian Style

Mauro Colombo; Silvia Vitali; Chiara Cutaia; Eleonora Marelli; Antonio Guaita. 2015. "Rehabilitative Outcomes after Hip Fracture in a Special Care Unit for Persons with Dementia and Behavioral and Psychotic Symptoms." Health 07, no. 09: 1175-1182.

Study protocol
Published: 24 September 2013 in BMC Geriatrics
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Developed countries are experiencing an unprecedented increase in life expectancy that is accompanied by a tremendous rise in the number of people with dementia. The purpose of this paper is to report on the study design and methodology of an Italian population-based study on brain aging and dementia in the elderly. This multi-domain study is structured in two phases. Our goal is to gather sufficient data to estimate the prevalence (phase I: cross-sectional study), the incidence and the progression of dementia and its subtypes as well as cognitive impairment (phase II: follow-up study) and to identify socio-demographic, clinical, and lifestyle factors associated with dementia and the quality of brain aging in people aged 70–74 years, a crucial point between late adulthood and old age. We chose to contact all 1773 people born between 1935–39 residing in Abbiategrasso, Milan, Italy. Those who agreed to participate in the “Invece.Ab” study were enrolled in a cross-sectional assessment and will be contacted two and four years after the initial data collection to participate in the longitudinal survey. Both the cross-sectional and longitudinal assessments include a medical evaluation, a neuropsychological test battery, several anthropometric measurements, a social and lifestyle interview, blood analyses, and the storage of a blood sample for the evaluation of putative biological markers. Now at the end of the recruitment phase, the evaluable population has amounted to 1644 people. Among these, 1321 (80.35%) of the participants have completed phase I. This high return rate was likely due to the style of recruitment and personalization of the contacts. NCT01345110

ACS Style

Antonio Guaita; Mauro Colombo; Roberta Vaccaro; Silvia Fossi; Silvia Francesca Vitali; Gianluigi Forloni; Letizia Polito; Annalisa Davin; Virginia Valeria Ferretti; Simona Villani. Brain aging and dementia during the transition from late adulthood to old age: design and methodology of the “Invece.Ab” population-based study. BMC Geriatrics 2013, 13, 98 -98.

AMA Style

Antonio Guaita, Mauro Colombo, Roberta Vaccaro, Silvia Fossi, Silvia Francesca Vitali, Gianluigi Forloni, Letizia Polito, Annalisa Davin, Virginia Valeria Ferretti, Simona Villani. Brain aging and dementia during the transition from late adulthood to old age: design and methodology of the “Invece.Ab” population-based study. BMC Geriatrics. 2013; 13 (1):98-98.

Chicago/Turabian Style

Antonio Guaita; Mauro Colombo; Roberta Vaccaro; Silvia Fossi; Silvia Francesca Vitali; Gianluigi Forloni; Letizia Polito; Annalisa Davin; Virginia Valeria Ferretti; Simona Villani. 2013. "Brain aging and dementia during the transition from late adulthood to old age: design and methodology of the “Invece.Ab” population-based study." BMC Geriatrics 13, no. 1: 98-98.

Journal article
Published: 01 April 2011 in Gerontechnology
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Mauro Colombo. Envisions and pitfalls in suitable environments for people with dementia. Gerontechnology 2011, 10, 1 .

AMA Style

Mauro Colombo. Envisions and pitfalls in suitable environments for people with dementia. Gerontechnology. 2011; 10 (2):1.

Chicago/Turabian Style

Mauro Colombo. 2011. "Envisions and pitfalls in suitable environments for people with dementia." Gerontechnology 10, no. 2: 1.

Comparative study
Published: 31 December 2009 in Archives of Gerontology and Geriatrics
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The clock drawing test (CDT) is an easy to apply, well accepted and reliable test that is widely used to screen for visuo-constructional difficulties in the aged people. Yet, besides visual agnosia and constructional apraxia, executive control influences performances in this task. Execution modalities and rating schemes vary widely, as for the way stimuli are proposed, the time to which the clock is set, and the elements that are considered for scoring. The scoring system we have selected is called clock drawing interpretation scale (CDIS) contains 20 items in 3 areas: visuo-perceptual, attentional and numerical factors. Our aim is to know the meanings of the CDIS total and sub-areas score, investigating the relationships with specific neuropsychological tests, in elderly persons with moderate cognitive impairment. CDIS has been administered to 90 people, aged about 75 years, attending our rehabilitative day hospital or our memory clinic. A neuropsychological battery has been administered to a sample of 47 outpatients, selected by contingence. Respective mean MMSE for the 2 samples are 24 and 25.1 (adjusted for age and education). The score method shows good internal consistency, with Cronbach's a about 0.75, either for total score or for the 3 sub-scores. Both total score and all sub-scores share correlations with mini mental state examination (MMSE), geriatric depression scale (GDS 5-item form), digit-symbol test, phonetic fluency and constructional apraxia tests. Total score and Group A (visuo-perceptive items) correlate also with cancellation attentional matrices, trail making test A and B, Corsi's cubes and Raven's colored matrices. Group B (attention items) and Group C (numerical factors) lack some of these correlations (Pearson correlation coefficients between 0.264 and 0.629). Neither CDIS total score nor sub-scores (except for numerical factors) correlate with verbal learning and memory. CDIS total cores correlates also with the level of education (r=0.418; p=0.001), but not with age. In conclusion, the clock drawing test, scored by the 20-item CDIS, looks as a homogeneous and analytic test, which is focused on visuo-perceptive and executive skills, while it disregards verbal learning and memory, in elderly people with moderate cognitive impairment. Its 3-item groups show good internal consistency; they also plausibly correlate to specific neuropsychological tests. The almost overlapping results of total and visuo-perceptual sub-score come from the way the test is performed and evaluated. The correlation between CDIS and GDS confirms the relevance of mood towards executive functions.

ACS Style

Mauro Colombo; R. Vaccaro; S.F. Vitali; M. Malnati; A. Guaita. CLOCK DRAWING INTERPRETATION SCALE (CDIS) AND NEURO-PSYCHOLOGICAL FUNCTIONS IN OLDER ADULTS WITH MILD AND MODERATE COGNITIVE IMPAIRMENTS. Archives of Gerontology and Geriatrics 2009, 49, 39 -48.

AMA Style

Mauro Colombo, R. Vaccaro, S.F. Vitali, M. Malnati, A. Guaita. CLOCK DRAWING INTERPRETATION SCALE (CDIS) AND NEURO-PSYCHOLOGICAL FUNCTIONS IN OLDER ADULTS WITH MILD AND MODERATE COGNITIVE IMPAIRMENTS. Archives of Gerontology and Geriatrics. 2009; 49 ():39-48.

Chicago/Turabian Style

Mauro Colombo; R. Vaccaro; S.F. Vitali; M. Malnati; A. Guaita. 2009. "CLOCK DRAWING INTERPRETATION SCALE (CDIS) AND NEURO-PSYCHOLOGICAL FUNCTIONS IN OLDER ADULTS WITH MILD AND MODERATE COGNITIVE IMPAIRMENTS." Archives of Gerontology and Geriatrics 49, no. : 39-48.

Comparative study
Published: 31 December 2009 in Archives of Gerontology and Geriatrics
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The ability of decoding the emotional facial expressions may be early damaged in frontotemporal dementia, but relatively well preserved in the Alzheimer's disease (AD). Nevertheless, the data about the relationship of the dementia severity with the ability of recognizing the face emotions are conflicting and insufficient, mainly for the moderate-severe stage of the disease. The present study extends to the existing literature by: (1) assessing people in the moderate and severe stage of dementia, compared with people without cognitive impairment; (2) assessing not only recognition but also reactivity to the facial expression of emotion. The capability of understanding the facial emotions has been evaluated in 79 patients with dementia compared to 64 healthy elderly people. The test consisted in showing them 14 photographic representations of 7 emotions both from male and from female faces, representing happiness, sadness, fear, disgust, boredom, anger and surprise. Patients were asked to observe the face and to recognize the emotion either with a denomination or a description. Then the spontaneous reactivity to the face expressions was videotaped and classified as a congruous or incongruous reaction by two independent observers who showed a good inter-rater reliability. Of the patients, 53% with dementia recognized up to 5 emotions out of 14, while in the healthy controls this number of mean recognition raised to 8.4, a value reached by the patients who scored 16 at MMSE. The most identified emotion is happiness both for the patients and for the controls. In general, positive emotions are better recognized than the negative ones, confirming the literary data. About the reactions to face emotion stimuli, there is no significant difference for any of the face emotion between the control group and the people with dementia. These data show that patients with dementia can recognize and react to facial emotions also in the severe stage of the disease, suggesting the usefulness of a non-verbal, emotional communication and supporting the need for more emotional education for care givers, both relatives and professionals.

ACS Style

A. Guaita; M. Malnati; R. Vaccaro; R. Pezzati; J. Marcionetti; S.F. Vitali; Mauro Colombo. IMPAIRED FACIAL EMOTION RECOGNITION AND PRESERVED REACTIVITY TO FACIAL EXPRESSIONS IN PEOPLE WITH SEVERE DEMENTIA. Archives of Gerontology and Geriatrics 2009, 49, 135 -146.

AMA Style

A. Guaita, M. Malnati, R. Vaccaro, R. Pezzati, J. Marcionetti, S.F. Vitali, Mauro Colombo. IMPAIRED FACIAL EMOTION RECOGNITION AND PRESERVED REACTIVITY TO FACIAL EXPRESSIONS IN PEOPLE WITH SEVERE DEMENTIA. Archives of Gerontology and Geriatrics. 2009; 49 ():135-146.

Chicago/Turabian Style

A. Guaita; M. Malnati; R. Vaccaro; R. Pezzati; J. Marcionetti; S.F. Vitali; Mauro Colombo. 2009. "IMPAIRED FACIAL EMOTION RECOGNITION AND PRESERVED REACTIVITY TO FACIAL EXPRESSIONS IN PEOPLE WITH SEVERE DEMENTIA." Archives of Gerontology and Geriatrics 49, no. : 135-146.

Journal article
Published: 27 January 2009 in The Open Geriatric Medicine Journal
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Customer Satisfaction as a Quality Factor in Geriatric Rehabilitation

ACS Style

Maria Mauro Colombo; Antonio Guaita; Maria Cottino; Marco Cairati; Danila Ferrari; Carla Gandolfi; Angela Mercanti; Mauro Colombo; Albert Cottino; Giorgio Previderè; Giuseppe Procino; Maria Carla Gandolfi; Rosaria Tararà. Customer Satisfaction as a Quality Factor in Geriatric Rehabilitation. The Open Geriatric Medicine Journal 2009, 2, 1 -4.

AMA Style

Maria Mauro Colombo, Antonio Guaita, Maria Cottino, Marco Cairati, Danila Ferrari, Carla Gandolfi, Angela Mercanti, Mauro Colombo, Albert Cottino, Giorgio Previderè, Giuseppe Procino, Maria Carla Gandolfi, Rosaria Tararà. Customer Satisfaction as a Quality Factor in Geriatric Rehabilitation. The Open Geriatric Medicine Journal. 2009; 2 (1):1-4.

Chicago/Turabian Style

Maria Mauro Colombo; Antonio Guaita; Maria Cottino; Marco Cairati; Danila Ferrari; Carla Gandolfi; Angela Mercanti; Mauro Colombo; Albert Cottino; Giorgio Previderè; Giuseppe Procino; Maria Carla Gandolfi; Rosaria Tararà. 2009. "Customer Satisfaction as a Quality Factor in Geriatric Rehabilitation." The Open Geriatric Medicine Journal 2, no. 1: 1-4.

Journal article
Published: 01 January 2007 in Archives of Gerontology and Geriatrics
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BPSD are very frequent, so that 90% of demented patients have at least one. BPSD are troublesome both for elders with dementia and for caregivers, fostering the institutionalization. Yet, BPSD may vary as long as the disease progresses, and may fluctuate in the short run, either spontaneously or by pharmacological as well as non-pharmacological interventions. The aim of the study was to investigate by factor analysis possible groupings among the modifications occurring in BPSD, during the stay in a special care unit (SCU). BPSD were rated through the neuropsychiatric inventory (NPI); frequency x severity scores were calculated for any single BPSD at entry and at discharge: the differences were analyzed using factor analysis. The sample comprised 214 demented persons, 65.4% females; of mean age 79.6 years; Overall entry score of NPI was 46.1+/-20.7; NPI overall mean difference at discharge=-30.4+/-20.3. BPSD factor analysis on frequency x severity crude baseline scores resulted in 4 groups: 1 (agitation+irritability+aberrant motor activity+disinhibition); 2 (delusions+hallucinations); 3 (anxiety+dysphoria); 4 (apathy+euphoria). When differences (discharge frequency x severity-entry frequency x severity) for each BPSD scores were factor analyzed, grouping was rather similar: (i) agitation+irritability; (ii) delusions+hallucinations; (iii) anxiety+dysphoria+aberrant motor activity; (iv) euphoria+disinhibition; (v) apathy. In our sample, BPSD improved during the stay in the SCU. These improvements followed trajectories that looked plausible and were consistent with baseline groupings, by factor analysis.

ACS Style

M. Colombo; S. Vitali; M. Cairati; R. Vaccaro; G. Andreoni; A. Guaita. Behavioral and psychotic symptoms of dementia (BPSD) improvements in a special care unit: A factor analysis. Archives of Gerontology and Geriatrics 2007, 44, 113 -120.

AMA Style

M. Colombo, S. Vitali, M. Cairati, R. Vaccaro, G. Andreoni, A. Guaita. Behavioral and psychotic symptoms of dementia (BPSD) improvements in a special care unit: A factor analysis. Archives of Gerontology and Geriatrics. 2007; 44 ():113-120.

Chicago/Turabian Style

M. Colombo; S. Vitali; M. Cairati; R. Vaccaro; G. Andreoni; A. Guaita. 2007. "Behavioral and psychotic symptoms of dementia (BPSD) improvements in a special care unit: A factor analysis." Archives of Gerontology and Geriatrics 44, no. : 113-120.

Journal article
Published: 01 January 2004 in Archives of Gerontology and Geriatrics
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A study has been carried out in our geriatric rehabilitation wards, to know better the role of cognitive dysfunction in treatment outcome and processing, mainly functional recovery and comorbidity. We analyzed 478 frail inpatients, 2/3 of them were females, aged 78.7 + 9.2 years, consecutively admitted to the unit. Assessment of cognitive function was performed by the mini mental state examination (MMSE), of functional status by Barthel index (BI), of co-morbidity by cumulative illness rating scale (CIRS) both at the admission and discharge for each patient, together with the usual clinical parameters and social outcome. More than one people in three lived alone and showed some communication problems; one in seven needed modifications in food preparation or nutritional system;more than one in five had pressure sore >/= 2 (EPUAP = European Pressure Ulcers Advisory Panel classification). The mean (+/- SD) levels of the admitted were: MMSE = 20 +/- 7.2; BI total score = 45.5 +/- 28.9; CIRS class = 4 +/- 2, CIRS severity score = 1.9 +/- 0.4. Of the patients, 74.5% were discharged to home. Mean functional gain was 20 points at BI: 65.6 +/-30.7; MMSE improved to 21.6 +/- 7.1 (p = 0.00005 for both comparisons, by Wilcoxon test).MMSE was positively correlated to BI (r = 0.6, p = 0.0005) and negatively correlated (p =0.0005) to CIRS comorbidity (r = -0.33) and severity (r = -0.26), and to age (r = -0.38, p =0.0005) both at admission and at discharge. MMSE at admission was correlated neither to functional gain, nor to improvement of clinical indicators, nor to measures of functional and clinical efficiency. MMSE at discharge showed similar results. In a stepwise multiple correlation analysis, taking the gain in BI as the dependent variable, while BI, serum albumin level, MMSE, CIRS severity and comorbidity indexes at admission as independent variables, MMSE together with BI admission total score and CIRS severity index retained a strong association with functional gain, whilst admission serum albumin levels and CIRSindex lost it. Consistently with some literary data, we showed the actual possibility of functional and clinical gains for people cared in a geriatric rehabilitation ward, all through a wide range of MMSE score, including subnormal scores. Poor cognitive status bears heavily on frailty, but does not hamper the outcomes of genuine rehabilitative efforts in geriatrics.

ACS Style

Mauro Colombo; A. Guaita; M. Cottino; G. Previdere’; D. Ferrari; S. Vitali. THE IMPACT OF COGNITIVE IMPAIRMENT ON THE REHABILITATION PROCESS IN GERIATRICS. Archives of Gerontology and Geriatrics 2004, 38, 85 -92.

AMA Style

Mauro Colombo, A. Guaita, M. Cottino, G. Previdere’, D. Ferrari, S. Vitali. THE IMPACT OF COGNITIVE IMPAIRMENT ON THE REHABILITATION PROCESS IN GERIATRICS. Archives of Gerontology and Geriatrics. 2004; 38 (9):85-92.

Chicago/Turabian Style

Mauro Colombo; A. Guaita; M. Cottino; G. Previdere’; D. Ferrari; S. Vitali. 2004. "THE IMPACT OF COGNITIVE IMPAIRMENT ON THE REHABILITATION PROCESS IN GERIATRICS." Archives of Gerontology and Geriatrics 38, no. 9: 85-92.

Journal article
Published: 01 January 2001 in Archives of Gerontology and Geriatrics
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ACS Style

Mauro Colombo; S. Vitali; M. Cairati; R. Perelli-Cippo; O. Bessi; P. Gioia; A. Guaita. Wanderers: Features, findings, issues. Archives of Gerontology and Geriatrics 2001, 33, 99 -106.

AMA Style

Mauro Colombo, S. Vitali, M. Cairati, R. Perelli-Cippo, O. Bessi, P. Gioia, A. Guaita. Wanderers: Features, findings, issues. Archives of Gerontology and Geriatrics. 2001; 33 ():99-106.

Chicago/Turabian Style

Mauro Colombo; S. Vitali; M. Cairati; R. Perelli-Cippo; O. Bessi; P. Gioia; A. Guaita. 2001. "Wanderers: Features, findings, issues." Archives of Gerontology and Geriatrics 33, no. : 99-106.

Clinical trial
Published: 01 November 1998 in Age and Ageing
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Objective: to evaluate whether oral supplementation with zinc or zinc/arginine increases the antibody response to influenza vaccine or modulates the lymphocyte phenotype in elderly subjects. Design: a randomized controlled trial with two supplemented groups and one control group. Setting: a community nursing home. Participants: 384 subjects aged 64–100 (mean age 82 years) examined in three separate studies. Intervention: oral supplementation with zinc (400 mg/day) or zinc plus arginine (4 g/day) for 60 days starting 15 days before influenza vaccination. The control groups received vaccine only. Measurements: haematological and nutritional indices, antibody titre against influenza viral antigens, lymphocyte phenotype. Results: supplementation with zinc or zinc plus arginine increased zinc plasma concentrations restoring the age-related impairment in zinc concentrations to values found in younger people. The antibody titre against influenza viral antigens was not increased in zinc or zinc/arginine supplemented groups in comparison with subjects receiving vaccine alone. The number of CD3, CD4 or CD8 lymphocytes was not affected by zinc or zinc/arginine supplementation. Conclusion: prolonged supplementation with zinc or zinc/arginine restores zinc plasma concentrations but is ineffective in inducing or ameliorating the antibody response after influenza vaccination in elderly subjects.

ACS Style

Mauro Provinciali; Alessio Montenovo; Giuseppina di Stefano; Mauro Colombo; Laura Daghetta; Marco Cairati; Claudio Veroni; Roberto Cassino; Fabrizio Delia Torre; Nicola Fabris. Effect of zinc or zinc plus arginine supplementation on antibody titre and lymphocyte subsets after influenza vaccination in elderly subjects: a randomized controlled trial. Age and Ageing 1998, 27, 715 -722.

AMA Style

Mauro Provinciali, Alessio Montenovo, Giuseppina di Stefano, Mauro Colombo, Laura Daghetta, Marco Cairati, Claudio Veroni, Roberto Cassino, Fabrizio Delia Torre, Nicola Fabris. Effect of zinc or zinc plus arginine supplementation on antibody titre and lymphocyte subsets after influenza vaccination in elderly subjects: a randomized controlled trial. Age and Ageing. 1998; 27 (6):715-722.

Chicago/Turabian Style

Mauro Provinciali; Alessio Montenovo; Giuseppina di Stefano; Mauro Colombo; Laura Daghetta; Marco Cairati; Claudio Veroni; Roberto Cassino; Fabrizio Delia Torre; Nicola Fabris. 1998. "Effect of zinc or zinc plus arginine supplementation on antibody titre and lymphocyte subsets after influenza vaccination in elderly subjects: a randomized controlled trial." Age and Ageing 27, no. 6: 715-722.