Background: Protein–protein interactions (PPIs) are of great importance in cellular systems of organisms, since they are the basis of cellular structure and function and many essential cellular processes are related to that. Most proteins perform their functions by interacting with other proteins, so predicting PPIs accurately is crucial for understanding cell physiology. Results: Recently, graph convolutional networks (GCNs) have been proposed to capture the graph structure information and generate representations for nodes in the graph. In our paper, we use GCNs to learn the position information of proteins in the PPIs networks graph, which can reflect the properties of proteins to some extent. Combining amino acid sequence information and position information makes a stronger representation for protein, which improves the accuracy of PPIs prediction. Conclusion: In previous research methods, most of them only used protein amino acid sequence as input information to make predictions, without considering the structural information of PPIs networks graph. We first time combine amino acid sequence information and position information to make representations for proteins. The experimental results indicate that our method has strong competitiveness compared with several sequence-based methods.
Owing to the attractive properties of decentralization, unforgeability, transparency, and traceability, blockchain is increasingly being used in various scenarios such as supply chain and public services, where massive Spatial-Temporal-Keywords (STK) transactions need to be packaged to the blockchain systems. However, due to the multi-dimensionality of STK transactions and transaction randomness among different blocks, existing solutions fail to enable queries in a verifiable and efficient way for blockchains storing multidimensional transactions. To this end, this paper takes the first step to innovatively propose an authenticated and efficient query approach in hybrid blockchain systems consisting of on-chain and off-chain parts. We first design a new data structure named MRK-Tree in the block body, which organizes STK transactions for efficient nodes pruning of both kNN and range queries. Then we propose an improved block header, which improves the efficient pruning of blocks on the basis of ensuring the authentication of query results. Also, we design a cross-block searching algorithm named Efficient Block Pruning (EBP) and intra-block searching algorithms named Authenticated kNN/Range Query (AKQ/ARQ) to accelerate authenticated queries for multiple MRK-Trees in the hybrid blockchain systems. Authentication mechanisms are proposed to ensure the soundness and completeness of query results. Rigorous security analysis validates the practicability of the proposed approach. We build a blockchain prototype to comprehensively evaluate the performance of proposed query schemes. Extensive evaluation results with real datasets reveal that our approach can ensure authenticated queries, meanwhile improving the time efficiency by up to 36.45x and space efficiency by up to 4 orders of magnitude compared with the well-known benchmark query schemes.
In an intelligent driving environment, monitoring the physiological state of drivers is crucial for ensuring driving safety. This paper proposes a method for monitoring and analyzing driver physiological characteristics by combining electronic vehicle identification (EVI) with multimodal biometric recognition. The method aims to efficiently monitor the driver’s heart rate, breathing frequency, emotional state, and fatigue level, providing real-time feedback to intelligent driving systems to enhance driving safety. First, considering the precision, adaptability, and real-time capabilities of current physiological signal monitoring devices, an intelligent cushion integrating MEMSs (Micro-Electro-Mechanical Systems) and optical sensors is designed. This cushion collects heart rate and breathing frequency data in real time without disrupting the driver, while an electrodermal activity monitoring system captures electromyography data. The sensor layout is optimized to accommodate various driving postures, ensuring accurate data collection. The EVI system assigns a unique identifier to each vehicle, linking it to the physiological data of different drivers. By combining the driver physiological data with the vehicle’s operational environment data, a comprehensive multi-source data fusion system is established for a driving state evaluation. Secondly, a deep learning model is employed to analyze physiological signals, specifically combining Convolutional Neural Networks (CNNs) and Long Short-Term Memory (LSTM) networks. The CNN extracts spatial features from the input signals, while the LSTM processes time-series data to capture the temporal characteristics. This combined model effectively identifies and analyzes the driver’s physiological state, enabling timely anomaly detection. The method was validated through real-vehicle tests involving multiple drivers, where extensive physiological and driving behavior data were collected. Experimental results show that the proposed method significantly enhances the accuracy and real-time performance of physiological state monitoring. These findings highlight the effectiveness of combining EVI with multimodal biometric recognition, offering a reliable means for assessing driver states in intelligent driving systems. Furthermore, the results emphasize the importance of personalizing adjustments based on individual driver differences for more effective monitoring.
Traffic congestion is a common problem in many countries, especially in big cities. At present, China’s urban road traffic accidents occur frequently, the occurrence frequency is high, the accident causes traffic congestion, and accidents cause traffic congestion and vice versa. The occurrence of traffic accidents usually leads to the reduction of road traffic capacity and the formation of traffic bottlenecks, causing the traffic congestion. In this paper, the formation and propagation of traffic congestion are simulated by using the improved medium traffic model, and the control strategy of congestion dissipation is studied. From the point of view of quantitative traffic congestion, the paper provides the fact that the simulation platform of urban traffic integration is constructed, and a feasible data analysis, learning, and parameter calibration method based on RBF neural network is proposed, which is used to determine the corresponding decision support system. The simulation results prove that the control strategy proposed in this paper is effective and feasible. According to the temporal and spatial evolution of the paper, we can see that the network has been improved on the whole.
Feedback linearization technique is a relative mature design technique in nonlinear control system theory, the backstepping technique is a controller design technique which recently gets much favor. The feedback linearization based on backstepping technique is the combination of the two techniques mentioned, it uses backstepping design process, designs a sequence of ¿virtual¿ systems of relative degree one, reduces the relative degree by one by choosing a ¿virtual¿ input, achieves passivity with respect to a ¿virtual output¿, and the last ¿virtual output¿ is used to close feedback loop. The design process is distinct, and it can make both strictly feedback nonlinear system and pure feedback nonlinear system to linear system by feedback linearization, and the simulation result demonstrates the above conclusion.
Because of the continuous progress of vehicle hardware, the condition where the vehicle cannot load a complex algorithm no longer exists. At the same time, with the progress of vehicle hardware, the number of texts shows exponential growth in actual operation. In order to optimize the efficiency of mass data transmission in actual operation, this paper presented the text information (including position information) of the maximum entropy principle of a neural network probability prediction model combined with the optimized Huffman encoding algorithm, optimization from the exchange of data to data compression, transmission, and decompression of the whole process. The test results show that the text type vehicle information based on compressed algorithm to optimize the algorithm of data compression and transmission can effectively realize data compression. It can also achieve a higher compression rate and data transmission integrity, and after decompression it can basically guarantee no distortion. The method proposed in this paper is of great significance for improving the transmission efficiency of vehicle text information, improving the interpretability and integrity of text information, realizing vehicle monitoring, and grasping real‐time traffic conditions.