An efficient continuous-wave, widely tunable, intra-cavity optical parametric oscillator (OPO) based on periodically poled MgO:LiNbO ₃ (MgO:PPLN) with a compact three-mirror linear cavity was demonstrated. The mode radii of fundamental and OPO cavities with plane and concave mirrors were calculated and theoretically compared. The result shows that the fundamental laser beam could be compressed, and its power density on the MgO:PPLN crystal could be improved by optimizing concave radii of cavity mirrors. Meanwhile, better mode matching between fundamental cavity and OPO cavity could be realized. A widely tunable signal spectrum from 1.43 to $1.79~\mu \text{m}$ and an idler spectrum from 2.62 to $4.16~\mu \text{m}$ were achieved as the OPO system derived by a diode laser end-pumped Nd:YVO ₄ crystal laser at 1064 nm. The maximum total output power up to 6.35 W (signal output power of about 4.24 W at $1.60~\mu \text{m}$ and idler output power of about 2.11 W at $3.17~\mu \text{m}$ ) and conversion efficiency of 31.6% were obtained at an incident pump power of 20.1 W.

We investigate the phase behavior of the asymmetric lipid membranes under shear flows, using the dissipative particle dynamics simulation. Two cases, the weak and strong shear flows, are considered for the asymmetric lipid microstructures. Three typical asymmetric structures, the membranes, tubes, and vesicle, are included in the phase diagrams, where the effect of two different types of lipid chain length on the formation of asymmetric membranes is evaluated. The dynamic processes are demonstrated for the asymmetric membranes by calculating the average radius of gyration and shape factor. The result indicates that different shear flows will affect the shape of the second type of lipid molecules; the shape of the first type of lipid molecules is more stable than that of the second type of lipid molecules. The mechanical properties are investigated for the asymmetric membranes by analyzing the interface tension. The results reveal an absolute pressure at the junctions of different types of particles under the weak shear flow; the other positions are almost in a state of no pressure; there is almost no pressure inside the asymmetric lipid membrane structure under the strong shear flow. The findings will help us to understand the potential applications of asymmetric lipid microstructures in the biological and medical fields.

In this work, the interactions between bottlebrush polymers and phospholipid membranes were investigated using dissipative particle dynamics simulations. The weak and strong adsorption phenomena between the polymers and membranes were examined by calculating the system parameters. A spring model was introduced to explain the variances in the shape factors and the radius of gyration of the bottlebrush polymers, as well as the order parameters of the phospholipid membrane in the pulling processes. This work provides further understanding for the application of bottlebrush polymers in biological processes.