Dorina Chambre

Dr. Dorina Chambre


Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
21 April 2022 in Antioxidants
Verified
Journal Article
Open access
PDF file
MMMaria-Daniela Mot
Maria-Daniela Mot
SGSimona Gavrilas
Simona Gavrilas
LALupitu Andreea
Lupitu Andreea
CMCristian Moisa
Cristian Moisa
DCDorina Chambre
Dorina Chambre
Simona BungăuSimona Bungău
Simona Bungău
The purpose of this study is to reveal the chemical and biochemical characteristics and the potential aromatherapy applications of the essential oil (EO) of Salvia officinalis (common sage) within a hospital environment. The chemical composition was determined by gas chromatography with mass spectrometry and ATR-FTIR spectroscopy. Three types of sage EOs were included in this study: two commercial oils and one oil obtained by in-house hydrodistillation. Based on the findings, these EOs were included in different chemotypes. The first two samples were similar to the most common chemotype (α-thujone > camphor > 1,8-cineole > β-thujone), while the in-house sage EO revealed a high content of 1,8-cineole, borneol, α-thujone, similar to the Dalmatian type. The latter sample was selected to be evaluated for its antioxidant and medical effects, as borneol, a bicyclic monoterpene, is known as a substance with anesthetic and analgesic effects in traditional Asian medicine. The study suggests that the antioxidant capacity of the sage EO is modest (33.61% and 84.50% inhibition was determined by DPPH and ABTS assays, respectively), but also that the inhalation of sage EO with high borneol content by hospitalized patients could improve these patients’ satisfaction.

1 July 2021 in Molecules
Verified
Journal Article
Open access
PDF file
ACAdriana Cecilia Csakvari
Adriana Cecilia Csakvari
CMCristian Moisa
Cristian Moisa
DRDana Gina Radu
Dana Gina Radu
LOLeonard Marian Olariu
Leonard Marian Olariu
LALupitu Andreea
Lupitu Andreea
Dana Maria CopoloviciDana Maria Copolovici
Dana Maria Copolovici
Cannabis sativa L. (hemp) is a plant used in the textile industry and green building material industry, as well as for the phytoremediation of soil, medical treatments, and supplementary food products. The synergistic effect of terpenes, flavonoids, and cannabinoids in hemp extracts may mediate the biogenic synthesis of metal nanoparticles. In this study, the chemical composition of aqueous leaf extracts of three varieties of Romanian hemp (two monoecious, and one dioecious) have been determined by Fourier-Transformed Infrared spectroscopy (FT-IR), high-performance liquid chromatography, and mass spectrometry (UHPLC-DAD-MS). Then, their capability to mediate the green synthesis of silver nanoparticles (AgNPs) and their pottential antibacterial applications were evaluated. The average antioxidant capacity of the extracts had 18.4 ± 3.9% inhibition determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and 78.2 ± 4.1% determined by 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS™) assays. The total polyphenolic content of the extracts was 1642 ± 32 mg gallic acid equivalent (GAE) L−1. After this, these extracts were reacted with an aqueous solution of AgNO3 resulting in AgNPs, which were characterized by UV−VIS spectroscopy, FT-IR, scanning electron microscopy (SEM-EDX), and dynamic light scattering (DLS). The results demonstrated obtaining spherical, stable AgNPs with a diameter of less than 69 nm and an absorbance peak at 435 nm. The mixture of extracts and AgNPs showed a superior antioxidant capacity of 2.3 ± 0.4% inhibition determined by the DPPH• assay, 88.5 ± 0.9% inhibition as determined by the ABTS•+ assay, and a good antibacterial activity against several human pathogens: Escherichia coli, Klebsiella pneumoniae, Pseudomonas fluorescens, and Staphylococcus aureus.

20 July 2021 in Molecules
Verified
Journal Article
Open access
PDF file
MBMihaela Alexandra Bogdan
Mihaela Alexandra Bogdan
Simona BungăuSimona Bungău
Simona Bungău
Delia Mirela TitDelia Mirela Tit
Delia Mirela Tit
DANA CARMEN ZAHADANA CARMEN ZAHA
DANA CARMEN ZAHA
ANAurelia Cristina Florian Nechifor
Aurelia Cristina Florian Nechifor
Dana Maria CopoloviciDana Maria Copolovici
Dana Maria Copolovici
Chemical composition, antioxidant capacity, and antimicrobial activity of lavender essential oils (LEOs) extracted from three different varieties of Lavandula angustifolia Mill. (1-Moldoveanca 4, 2-Vis magic 10, and 3-Alba 7) have been determined. These plants previously patented in the Republic of Moldova were cultivated in an organic agriculture system in the northeastern part of Romania and then harvested in 3 consecutive years (2017–2019) to obtain the essential oils. From the inflorescences in the complete flowering stage, the LEOs were extracted by hydrodistillation. Then, their composition was analyzed by gas chromatography coupled with mass spectrometry (GC-MS) and by Fourier Transformed Infrared spectroscopy (FT-IR). The major identified constituents are as follows: linalool (1: 32.19–46.83%; 2: 29.93–30.97%; 3: 31.97–33.77%), linalyl acetate (1: 17.70–35.18%; 2: 27.55–37.13%; 3: 28.03–35.32%), and terpinen-4-ol (1: 3.63–7.70%; 2: 3.06–7.16%; 3: 3.10–6.53%). The antioxidant capacity as determined by ABTS and DPPH assays indicates inhibition, with the highest activity obtained for LEO var. Alba 7 from 2019. The in vitro antimicrobial activities of the LEOs and combinations were investigated as well, by using the disk diffusion method and minimum inhibitory concentration (MIC) against the Gram-positive bacterial strain Staphylococcus aureus (ATCC 6538), Gram-negative Pseudomonas aeruginosa (ATCC 27858), Escherichia coli (ATCC 25922), the yeast Candida albicans (ATCC 10231), and clinical isolates. Our results have shown that LEOs obtained from the three studied varieties of L. angustifolia manifest significant bactericidal effects against tested microorganisms (Staphylococcus aureus and Escherichia coli), and antifungal effects against Candida albicans. The mixture of LEOs (Var. Alba 7) and geranium, respectively, in tea tree EOs, in different ratios, showed a significant enhancement of the antibacterial effect against all the studied strains, except Pseudomonas aeruginosa.

7 June 2022 in Sustainability
Verified
Journal Article
Open access
PDF file
ABAlexandru Bogdan
Alexandru Bogdan
DCDorina Chambre
Dorina Chambre
Dana Maria CopoloviciDana Maria Copolovici
Dana Maria Copolovici
TBTudor Bungau
Tudor Bungau
CBConstantin C. Bungau
Constantin C. Bungau
Lucian CopoloviciLucian Copolovici
Lucian Copolovici
This paper aims to present a comprehensive review of the literature on the definition and development of the concepts of heritage and sustainability. The harmful effects of various pollutants on the materials widely used in the construction of monuments/buildings, which are part of the national and international cultural heritage, are also highlighted. In addition, the paper draws attention to modern techniques for investigating the composition and diagnosis of the alteration of buildings materials with the focus on stone, limestone, and mortars/concrete. The present research also emphasizes that in the case of heritage buildings, different skills are needed not only related to heritage conservation and rehabilitation, but also skills related to heritage planning processes, and to sustainable constructions. For exemplification, the manuscript proposes specific conservation principles based on the case of Brasov city, located in the heart of Romania and being par excellence a medieval town with representative buildings for that period.

19 February 2012 in Journal of Thermal Analysis and Calorimetry
Verified
Journal Article
Closed access
PDF file
MSMaria-Raluca Szabo
Maria-Raluca Szabo
DCDorina Chambre
Dorina Chambre
CICornelia Idiţoiu
Cornelia Idiţoiu

2 April 2022 in Plants
Verified
Journal Article
Open access
PDF file
LALupitu Andreea
Lupitu Andreea
CMCristian Moisa
Cristian Moisa
SGSimona Gavrilas
Simona Gavrilas
MDMihaela Dochia
Mihaela Dochia
DCDorina Chambre
Dorina Chambre
Lucian CopoloviciLucian Copolovici
Lucian Copolovici
Climate change will determine a sharp increase in carbon dioxide in the following years. To study the influence of elevated carbon dioxide on plants, we grew 13 different species and varieties from the Brassicaceae family at three carbon dioxide concentrations: 400, 800, and 1200 ppmv. The photosynthetic parameters (assimilation rate and stomatal conductance to water vapor) increase for all species. The emission of monoterpenes increases for plants grown at elevated carbon dioxide while the total polyphenols and flavonoids content decrease. The chlorophyll content is affected only for some species (such as Lipidium sativum), while the β-carotene concentrations in the leaves were not affected by carbon dioxide.