Load following is the potential for a power plant to adjust its power output as demand and price for electricity\ud fluctuates throughout the day. In nuclear power plants, this is done by inserting control rods into the reactor\ud pressure vessel. This operation is very inefficient as nuclear power generation is composed almost entirely of\ud fixed and sunk costs; therefore, lowering the power output doesn’t significantly reduce generating costs and the\ud plant is thermo-mechanical stressed. A more efficient solution is to maintain the primary circuit at full power\ud and to use the excess power for cogeneration. This paper assesses the technical-economic feasibility of this\ud approach when applied to Small Modular Reactors (SMR) with two cogeneration technologies: algae-biofuel and\ud desalinisation. Multiple SMR are of particular interest due to the fractional nature of their power output. The\ud result shows that the power required by an algae-biofuel plant is not sufficient to justify the load following\ud approach, whereas it is in the case of desalination. The successive economic analysis, based on the real options\ud approach, demonstrates the economic viability of the desalination in several scenarios. In conclusion, the\ud coupling of SMR with a desalination plant is a realistic solution to perform efficient load following