Sustainable development has recently become the driving force of all the policies leading environmental, economic, and social aspects of our life. In the construction sector, a large number of technological innovations has been introduced thus leading to an assessment of the environmental impact of the production processes. In the present study, the environmental impact of the Italian ceramic tiles production is analyzed and discussed. The evolution trends of the main atmospheric pollutants and the management of water and solid wastes of ceramic tile plants have been investigated over a period greater than 10 years, considering three different layouts of production cycles. The current evaluation shows that the Italian ceramic tiles industry has considered the environmental assessment as a fundamental practice for its development since the late 1980s. The reported data prove the high level of excellence reached by the Italian ceramic tile production and demonstrate how attention to the environmental impact is a fundamental key for the ceramic tile sector.