The chemistry of heterocyclic compounds has traditionally been and remains a bright area of chemical science in Russia. This is due to the fact that many heterocycles find the widest application. These compounds are the key structural fragments of most drugs, plant protection agents. Many natural compounds are also derivatives of heterocycles. At present, more than half of the hundreds of millions of known chemical compounds are heterocycles. This collective review is devoted to the achievements of Russian chemists in this field over the last 15–20 years. The review presents the achievements of leading heterocyclists representing both RAS institutes and university science. It is worth noting the wide scope of the review, both in terms of the geography of author teams, covering the whole of our large country, and in terms of the diversity of research areas. Practically all major types of heterocycles are represented in the review. The special attention is focused on the practical applications of heterocycles in the design of new drugs and biologically active compounds, high-energy molecules, materials for organic electronics and photovoltaics, new ligands for coordination chemistry, and many other rapidly developing areas. These practical advances would not be possible without the development of new fundamental transformations in heterocyclic chemistry. Bibliography — 2237 references.

This review covers recent advances in C–H bromination of aromatic substrates. Transition-metal-catalyzed/-mediated reactions and transition-metal-free methods are discussed. 1 Introduction 2 Transition-Metal-Catalyzed Bromination 2.1 Palladium-Catalyzed Reactions 2.2 Rhodium-, Cobalt- and Ruthenium-Catalyzed Reactions 2.3 Copper-Mediated Reactions 2.4 Gold-Catalyzed Reactions 3 Transition-Metal-Free Bromination 3.1 Conventional Electrophilic Bromination 3.2 Oxidative Bromination 3.3 Bromination of Heterocyclic N-Oxides 4 Conclusions

A air and moisture stable square-planar trans-dichloropalladium(II) complex containing two 5-(p-tolyl)isoxazol-3-amine ligands was synthesized and structurally characterized by single-crystal X-ray diffraction. The isoxazol-3-amine ligand was prepared from 5-(p-tolyl)isoxazole-3-carbaldehyde oxime by successive transformations. The new complex is a high-turnover-number catalyst for the Suzuki-Miyaura reaction with low palladium loading (0.0001-0.1%) in neat water under an air atmosphere.