Doped (Ag + Fe) zinc targets were obtained: Zn/Ag/Fe (Zn96, Ag2, Fe 2%; Zn94, Ag2, Fe 4%; and Zn90, Ag2, Fe 8%). ZnO/Ag/Fe films with n- and p- type conductivity were obtained on glass substrates at room temperature using the method of DC-magnetron sputtering of Zn/Ag/Fe targets in a gas mixture of Ar : O₂, in a vacuum of about 0.666 Pa. The structural, electrophysical, optical, and morphological characteristics of the obtained films were studied. The research was conducted using X-ray diffraction (XRD), atomic force microscopy, UV/VIS spectroscopy, and Hall measurements. The X-ray diffraction patterns of the ZnO/Ag/Fe films with n- and p-type conductivity showed characteristic reflections of interplanar distances on glass substrates along the crystallographic directions 100, 002, and 101. The transmittance of these films is about 85–95% in the wavelength range of 400–930 nm. The ZnO/Ag/Fe films with p-type conductivity have a concentration of free carriers on the order of 10¹⁸ cm^–3. The ZnO/Ag/Fe films obtained at room temperature of the substrate can be used in the development of functional optoelectronic devices.

The formation of a Zn-containing complex on a ZnO target in an H₂O₂ vapor medium, the sublimation of this complex, and the decomposition of the complex to the original compound are considered. UV preirradiation of the target raises the concentration of the Zn-containing complex in the gas phase in proportion to the irradiation time. The rate constant of the decomposition of the complex on a substrate is reported. The activation energy and the preexponential factor (k ₀) for the decomposition reaction are derived from the temperature dependence of the rate constant. The fact that the activation energy of the decomposition of the complex is similar to that of hydrogen peroxide decomposition suggests that the complex has a peroxide-like structure. The experimental and calculated k ₀ data indicate that the decomposition reaction is monomolecular.

Low molecular mono- and diamines (3-aminopropyltriethoxysilane, hexamethylenediamine, 1,4-diaminobutane), and high molecular weight polydimethylsiloxane with terminal amine groups were studied as catalysts in the synthesis of cross-linked composite films based on polydimethylsiloxane with terminal hydroxyl groups, tetraethoxysilane a cross-linking agent and containing sodium diclofenac as a physiologically active compound. Polyethylene glycol PEG200 was used as a hydrophilizing component for the hydrophobic silicone matrix. The chemical structure of amine catalysts and polyethylene glycol presence have significant effect on structure and properties of the composites, thereby determining the kinetics and degree of prolonged release of diclofenac from the films.

This article represents the initial preformulation stage of a broader project aimed at evaluating polysiloxane films as carrier matrices for the TIODIN components thiamine bromide (ThBr) and sodium iodide (NaI). The specific gap addressed in this first part is the lack of information on how these two highly water-soluble crystalline salts are incorporated into hydrophobic crosslinked PDMS-based matrices, how they are distributed within such films, what solid-state forms and interactions may arise, and how these features relate to their release behaviour. Crosslinked films were prepared from α,ω-dihydroxypolydimethylsiloxane (PDMS–OH) of different viscosities, tetraethoxysilane (TEOS), and Sn(Oct)₂ as a catalyst. Raman spectroscopy, confocal Raman depth profiling, and X-ray diffraction showed that the films contain both individual ThBr and NaI crystallites and mixed crystalline domains consistent with partial ThBr/NaI association and/or iodide-exchanged phases. The fraction of such mixed domains was higher in films prepared from lower-viscosity PDMS–OH than in films based on higher-viscosity PDMS–OH, and depth profiling extended this trend into the accessible near-surface layers from both film sides. Release into physiological saline, used here as a simple comparative aqueous release medium, remained low, reaching approximately 9% for ThBr and 20% for NaI after 72 h, while film swelling was minimal, approximately 1–1.5%. These findings are consistent with restricted water penetration and diffusion-limited release from hydrophobic, weakly swelling matrices. Because this first part of the study is restricted to matrix characterisation, depth profiling, and release into saline, the present results should be regarded as preformulation data. They do not demonstrate skin permeation, therapeutic transdermal performance, or suitability as a complete patch dosage form but establish baseline structural and release characteristics for a planned Part 2 focused on more application-oriented film optimisation, including properties required for future transdermal patch development.