Gohar Khachatryan

Prof. Gohar Khachatryan

Faculty of Food Technology, University of Agriculture In Krakow
orcid

Research Focus & Metrics

Academic Career Length

24Years (2003-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2020 in Carbohydrate Polymers
Verified
Journal Article
Closed access
Ewelina JamrózEwelina Jamróz
Ewelina Jamróz
Gohar KhachatryanGohar Khachatryan
Gohar Khachatryan
Pavel KopelPavel Kopel
Pavel Kopel
LJLesław Juszczak
Lesław Juszczak
AKAgnieszka Kawecka
Agnieszka Kawecka
MZMalgorzata Zimowska
Malgorzata Zimowska

15 July 2021 in Polymers
Verified
Journal Article
Open access
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Magdalena KrystyjanMagdalena Krystyjan
Magdalena Krystyjan
Gohar KhachatryanGohar Khachatryan
Gohar Khachatryan
Maja GrabackaMaja Grabacka
Maja Grabacka
MKMarcel Krzan
Marcel Krzan
MWMariusz Witczak
Mariusz Witczak
LWLiliana Woszczak
Liliana Woszczak
The application of natural polymer matrices as medical device components or food packaging materials has gained a considerable popularity in recent years, this has occurred in response to the increasing plastic pollution hazard. Currently, constant progress is being made in designing two-component or three-component systems that combine natural materials which help to achieve a quality comparable to the purely synthetic counterparts. This study describes a green synthesis preparation of new bionanocomposites consisting of starch/chitosan/graphene oxide (GO), that possess improved biological activities; namely, good tolerability by human cells with concomitant antimicrobial activity. The structural and morphological properties of bionanocomposites were analyzed using the following techniques: dynamic light scattering, scanning and transmission electron microscopy, wettability and free surface energy determination, and Fourier transform infrared spectroscopy. The study confirmed the homogenous distribution of GO layers within the starch/chitosan matrix and their large particle size. The interactions among the components were stronger in thin films. Additionally, differential scanning calorimetry analysis, UV–vis spectroscopy, surface colour measurements, transparency, water content, solubility, and swelling degree of composites were also performed. The mechanical parameters, such as tensile strength and elongation at break (EAB) were measured in order to characterise the functional properties of obtained nanocomposites. The GO additive altered the thermal features of the composites and decreased their brightness. The EAB of composite was improved by the introduction of GO. Importantly, cell-based analyses revealed no toxic effect of the composites on HaCat keratinocytes and HepG2 hepatoma cells, although a pronounced bacteriostatic effect against various strains of pathogenic bacteria was observed. In conclusion, the starch/chitosan/GO nanocomposites reveal numerous useful physicochemical and biological features, which make them a promising alternative for purely synthetic materials.

Verified
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JSJoanna Mirosława Szczepankowska
Joanna Mirosława Szczepankowska
Gohar KhachatryanGohar Khachatryan
Gohar Khachatryan
Karen KhachatryanKaren Khachatryan
Karen Khachatryan
Magdalena KrystyjanMagdalena Krystyjan
Magdalena Krystyjan
Materials with a “nano” structure are increasingly used in medicine and biotechnology as drug delivery systems, bioimaging agents or biosensors in the monitoring of toxic substances, heavy metals and environmental variations. Furthermore, in the food industry, they have found applications as detectors of food adulteration, microbial contamination and even in packaging for monitoring product freshness. Carbon dots (CDs) as materials with broad as well as unprecedented possibilities could revolutionize the economy, if only their synthesis was based on low-cost natural sources. So far, a number of studies point to the positive possibilities of obtaining CDs from natural sources. This review describes the types of carbon dots and the most important methods of obtaining them. It also focuses on presenting the potential application of carbon dots in biotechnology and food technology.

1 January 2015 in LWT
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Journal Article
Closed access
Magdalena KrystyjanMagdalena Krystyjan
Magdalena Krystyjan
Wojciech CiesielskiWojciech Ciesielski
Wojciech Ciesielski
Gohar KhachatryanGohar Khachatryan
Gohar Khachatryan
MSMarek Sikora
Marek Sikora
PTPiotr Tomasik
Piotr Tomasik

26 February 2022 in Polymers
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Journal Article
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Magdalena KrystyjanMagdalena Krystyjan
Magdalena Krystyjan
Gohar KhachatryanGohar Khachatryan
Gohar Khachatryan
Karen KhachatryanKaren Khachatryan
Karen Khachatryan
MKMarcel Krzan
Marcel Krzan
Wojciech CiesielskiWojciech Ciesielski
Wojciech Ciesielski
JSJoanna Mirosława Szczepankowska
Joanna Mirosława Szczepankowska
Nanotechnology is a dynamically developing field of science, due to the unique physical, chemical and biological properties of nanomaterials. Innovative structures using nanotechnology have found application in diverse fields: in agricultural and food industries, where they improve the quality and safety of food; in medical and biological sciences; cosmetology; and many other areas of our lives. In this article, a particular attention is focused on carbon nanomaterials, especially graphene, as well as carbon nanotubes and carbon quantum dots that have been successfully used in biotechnology, biomedicine and broadly defined environmental applications. Some properties of carbon nanomaterials prevent their direct use. One example is the difficulty in synthesizing graphene-based materials resulting from the tendency of graphene to aggregate. This results in a limitation of their use in certain fields. Therefore, in order to achieve a wider use and better availability of nanoparticles, they are introduced into matrices, most often polysaccharides with a high hydrophilicity. Such composites can compete with synthetic polymers. For this purpose, the carbon-based nanoparticles in polysaccharides matrices were characterized. The paper presents the progress of ground-breaking research in the field of designing innovative carbon-based nanomaterials, and applications of nanotechnology in diverse fields that are currently being developed is of high interest and shows great innovative potential.

29 December 2021 in Materials
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Journal Article
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JDJoanna Dulinska-Litewka
Joanna Dulinska-Litewka
KDKacper Dykas
Kacper Dykas
DFDominik Felkle
Dominik Felkle
KKKarolina Karnas
Karolina Karnas
Gohar KhachatryanGohar Khachatryan
Gohar Khachatryan
AKAnna Karewicz
Anna Karewicz
For the last years scientific community has witnessed a rapid development of novel types of biomaterials, which properties made them applicable in numerous fields of medicine. Although nanosilver, well-known for its antimicrobial, anti-angiogenic, anti-inflammatory and anticancer activities, as well as hyaluronic acid, a natural polysaccharide playing a vital role in the modulation of tissue repair, signal transduction, angiogenesis, cell motility and cancer metastasis, are both thoroughly described in the literature, their complexes are still a novel topic. In this review we introduce the most recent research about the synthesis, properties, and potential applications of HA-nanosilver composites. We also make an attempt to explain the variety of mechanisms involved in their action. Finally, we present biocompatible and biodegradable complexes with bactericidal activity and low cytotoxicity, which properties suggest their suitability for the prophylaxis and therapy of chronic wounds, as well as analgetic therapies, anticancer strategies and the detection of chemical substances and malignant cells. Cited studies reveal that the usage of hyaluronic acid-silver nanocomposites appears to be efficient and safe in clinical practice.