Objective: We aimed to evaluate changes in the prevalence of Heavy Episodic Drinking (HED) and Risky Consumption (RC) in freshman college students between 2005, 2012 and 2016; and to identify the explanatory variables of these patterns of consumption using individual and pooled analyses. Methods: A cross-sectional study involving 5260 students was carried out in Spain in 2005, 2012 and 2016. HED and RC were determined using the Alcohol Use Disorders Identification Test. Another questionnaire was used to measure parental education level and alcohol use, alcohol-related problems, age of onset of alcohol use and alcohol-related expectancies. Adjusted Odds Ratios (ORs) of RC and HED and their 95% Confidence Intervals were estimated using logistic regression. Results: An increase in the prevalence rates of HED and RC was observed among women during the three-study periods, nonetheless there was no statistically significant difference in the prevalence rates among men. High maternal educational level, living away from parental home, initiating drinking before the age of 15 and having positive expectancies about drinking are associated with higher prevalence of RC in both genders. High positive expectancies and early onset of alcohol use are associated with higher rates of HED among men and women. Students recruited in 2012 and 2016 are protected against RC in comparison to those recruited in 2005. Conclusions: The age of alcohol consumption onset is the most influencing factor on HED and RC for both genders in the three-study periods. Alcohol prevention campaigns targeting youth at early ages can reduce risky drinking behaviors.

Purpose: Investigations suggest non-medical use of prescription drugs (NMUPD) is associated with heavy drinking and polydrug use among university students. Our aim is to determine the prevalence of NMUPD among university students and to analyze its association with alcohol, tobacco, and cannabis use, and to study the role of the age of drinking onset. Methods: Cohort study among university Spanish students (n = 1382). Heavy drinking (HED) and risky consumption (RC) were measured with the Alcohol Use Disorders Identification Test. Questions related to tobacco and cannabis consumption were also formulated. NMUPD refers to sedative, anxiety, or pain medication intake within the last 15 days without medical prescription. All variables were measured at 18, 20, and 27 years. Multilevel logistic regression for repeated measures was used to obtain adjusted OR (odds ratios). We analyzed the results from a gender perspective. Results: Prevalence of NMUPD were higher in students who already partook in NMUPD at the beginning of the study. NMUPD in women at 27 is 3 times higher than at 18, while in men it is twice. Among females, RC (OR = 1.43) and cannabis consumption (OR = 1.33) are risk factors for NMUPD, while later onset of alcohol use (OR = 0.66) constitutes a protective factor. No significant differences were found for males. Conclusions: NMUPD is prevalent among university students. RC and early onset of alcohol use were associated with higher prevalence of NMUPD in females. The prevalence of NMUPD increased with age in both sexes. Strategies for reducing risky drinking and delaying onset of drinking should be provided for university students. Pharmacists and parents should be alerted to the risk of NMUPD.

Las desigualdades en salud en la adolescencia se han asociado a la morbimortalidad de los sujetos. Este estudio pretende evaluar el efecto de género, nacionalidad e inequidades sociales sobre el consumo de alcohol, tabaco y cannabis en adolescentes en un contexto multicultural. Se ha realizado un estudio transversal entre los estudiantes de Educación Secundaria Obligatoria (ESO) de los institutos de Burela (Lugo) (n=238). Se utilizó el cuestionario “Factors de Risc en Estudiants de Secundária” diseñado por la Agència de Salut Pública de Barcelona. Variables independientes: nacionalidad y el dinero disponible semanal. Variables dependientes: expectativas y consumo de alcohol, con consumo de tabaco y marihuana. Se generaron modelos de regresión logística multivariante. La participación en el estudio alcanzó el 91%. La proporción de alumnos que ha probado el alcohol aumenta con la edad (27,3%, 47,7% y el 75,9%), como ocurre con el tabaco (1,8%, 7,6% y 17%) y el cannabis (0%, 3,1%, 7%). La mayor disponibilidad económica constituye un factor de riesgo para haber probado el alcohol (OR=3,01), para su consumo de riesgo (OR=3,35), para haberse emborrachado (OR=6,45) y para haber probado la marihuana (OR=15,30). Sexo y nacionalidad no han evidenciado relación con el consumo de ninguna de estas drogas. Los resultados de nuestro estudio muestran que el consumo de alcohol, tabaco y cannabis aumenta con la edad así como con la mayor disponibilidad económica. Los resultados constatan que los alumnos inmigrantes no constituyen un grupo de riesgo y por ello no deben ser estigmatizados.

The use of non-prescribed prescription drugs (NPPD) is common in post-modern societies and a significant proportion of youth consume NPPD concomitantly to other drugs. We studied the prevalence of this consumption among university students in Spain, and its relationship to different patterns of alcohol, tobacco, and cannabis use. A cohort study among university students (n=1,380) (2005–2015) was carried out. Students completed self-administered questionnaires at initial (n=1,363, 98.7%), at 2 years (n=875, 75%) and 9 years of follow-up (n=415, 30.5%). Consumption of medicines (last 15 days), risky alcohol consumption (RC), heavy episodic drinking (HED), and tobacco and cannabis use were measured. Multilevel logistic regressions for repeated measures were generated using consumption of medicines with or without medical prescription as dependent variables. Prevalence of RC, HED, tobacco and cannabis had significant reductions during the follow-up. The use of NPPD increased over time, from 35.5% and 33.3% at 18 and 22 years old, respectively, to 49.6% at 27 years old. The highest rates were found among cannabis, tobacco, RC and HED users. For females, cannabis and RC constitute signitifant risk factors for use of NPPD. Conversely, for males, tobacco and cannabis were risk factors for such use of medicines. Later onset of alcohol consumption constitutes a protective factor for females. Our results reveal high prevalence of NPDD among university students. Those who consume NPPD are -at the same time- more likely to be alcohol, tobacco, and cannabis users than those who take medication under prescription. Preventive strategies should be reinforced and focused on this target population to decrease these high levels of poly-consumption.

Antecedentes: los problemas de salud mental durante la adolescencia suponen un aumento de la morbimortalidad y la discapacidad. Se pretende testar la hipótesis de que el bullying y el consumo de sustancias psicoactivas están asociados al estado de ánimo negativo.Métodos: estudio transversal entre estudiantes de Educación Secundaria Obligatoria (ESO) (n=238) de los institutos de Burela (Lugo). El “estado de ánimo negativo” se definió a partir de los siguientes ítems: sentirse cansado/a, triste, desplazado/a, aburrido/a, desesperanzado/a, nervioso/a o insomne. Como variables independientes se consideraron: el binge drinking, el haber fumado alguna vez tabaco o cannabis, así como sus correspondientes percepciones de peligrosidad. Además, se midió la variable bullying. Se estimaron modelos de regresión de Poisson con varianza robusta y se obtuvieron Razones de Prevalencia (RP).Resultados: el 10,5% [IC95% (7,2-15,2)] de la población encuestada presentaba estado de ánimo negativo. La nula o baja percepción de peligrosidad para el cannabis [RP=2,6 (1,2-5,5)], haber probado alguna vez esta sustancia adictiva [RP=3,1 (1,1-8,9)] y haber sufrido bullying [RP=4,8 (2,4-9,6)] se asociaban al estado de ánimo negativo.Conclusiones: sería recomendable crear intervenciones para la mejora de la salud mental durante la adolescencia que tengan en cuenta el consumo de sustancias adictivas y el hecho de haber sufrido bullying.

The present study aimed to explore the differences in the consumption of alcohol, tobacco and cannabis, mood and bullying between adolescents. A cross-sectional study was carried out in five regions of Northern Spain (one in Galiza and four in central Catalonia) that share similar socioeconomic characteristics and encompass around 10,000 inhabitants each. Students living in Burela, Galiza (N = 71) were compared to those of Central Catalonia (N = 193). The independent variable was the municipality of residence. The dependent variables encompassed: weekly available pocket money, Family Affluence Scale, self-classified academic qualification, place of origin, alcohol consumption, tobacco and cannabis smoking, negative mood and bullying. The mean age and their 95% confidence intervals (95% CI) of participants were similar between the regions (Burela: 15.90 years (15.68–16.13) and Central Catalonia: 15.36 years (15.28–15.44)). More than half of the participants were females (Burela, Galiza (53.5%) and Catalonia (54.9%)). Prevalence ratios (PR) and their 95% CI were estimated using Poisson regression models. In comparison with adolescents from Burela (Galiza), those living in Central Catalonia had higher prevalence of diverse academic levels (adjusted PR = 3.92 (1.78–8.66)), tobacco consumption (adjusted PR = 2.41 (1.47–3.97)) and negative mood (adjusted PR = 5.97 (3.05–11.70)). Even when dealing with regions with similar socioeconomic characteristics and number of inhabitants, differences exist in terms of the socioeconomic level, tobacco consumption, mood and bullying, as reported by adolescents.