Irrational applications of insecticides on vegetable crops are very common in Bangladesh, resulting in harmful consequences for the environment and human health. Therefore, a study was conducted to evaluate the efficacy of biological and botanical insecticides on okra shoot and fruit borer grown in open fields. Four insecticides were used in this study, namely Bacillus thuringiensis (Bt), Spinosad 45 SC, Abamectin 1.8 EC, and Azadirachtin 1% EC an untreated control. The experiment used a randomized complete block design (RCBD) with three replications. The results showed that the rate of shoot infestation was the lowest in the Spinosad-treated plot (3.80%), and the highest was in the control (20.67%). The lowest fruit infestation (3.56%) was recorded in the treated plot of Spinosad. The rate of reduction of fruit infestation over control was 80.69, 60.14, 56.45, and 55.58% in the plots treated with Spinosad, Bt, Azadirachtin, and Abamectin, respectively. Consequently, the Spinosad-treated plot attained the highest yield (8.65 t ha⁻¹), which was followed by the plots treated with Azadirachtin (6.74 t ha⁻¹), Bt (6.28 t ha⁻¹), and Abamectin (6.12 t ha⁻¹). The highest net return and benefit–cost ratio (BCR) were 542.36 US$ and 2.64, obtained respectively from the Spinosad-treated plot. The second highest BCR (1.70) was obtained from the Azadiratin-treated plot, and the lowest BCR (1.18) was recorded in the Abamectin-treated plot. Therefore, the studied insect management practices could be incorporated to attain higher yields and economic benefits for growing okra in Bangladesh.