Mathilde Pruvost obtained her Ph.D. in Molecular and Cellular Aspects of Biology in 2016 in the laboratory of Prof. Denis Vivien (INSERM UMR-S 1237) at the University of Normandy (Caen, France). During her Ph.D., she investigated the role of a protease of the extracellular matrix (Adamts4) in the central nervous system, showing its expression by oligodendrocytes and role in developmental myelination, as well as its beneficial effects in rodent models of spinal cord injury and stroke. Dr. Pruvost then investigated the role of glial autophagy in neurological disorders as a postdoctoral fellow at the Icahn School of Medicine at Mount Sinai (New York, USA) in the laboratory of Prof. Zhenyu Yue. She next joined the team of Prof. Patrizia Casaccia (Advanced Science Research Center at The Graduate Center, CUNY, New York, USA) in 2018 to pursue her postdoctoral training assessing the role of epigenetics in oligodendrocytes during brain development and in Multiple Sclerosis.