Marina Lacasaña

Dr. Marina Lacasaña


Research Focus & Metrics

Academic Career Length

25Years (2002-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 October 2014 in Toxicology Letters
Verified
Journal Article
Closed access
BGB. González-Alzaga
B. González-Alzaga
MLMarina Lacasaña
Marina Lacasaña
CAC. Aguilar-Garduño
C. Aguilar-Garduño
MRMIGUEL RODRIGUEZ-BARRANCO
MIGUEL RODRIGUEZ-BARRANCO
FBF. Ballester
F. Ballester
AHAntonio Hernández
Antonio Hernández

29 January 2010 in Environmental Health
Verified
Journal Article
Open access
PDF file
FBFerran Ballester
Ferran Ballester
MEMarisa Estarlich
Marisa Estarlich
CICarmen Iñiguez
Carmen Iñiguez
SLSabrina Llop
Sabrina Llop
RRRosa Ramón
Rosa Ramón
MRMarisa Rebagliato
Marisa Rebagliato
Maternal exposure to air pollution has been related to fetal growth in a number of recent scientific studies. The objective of this study was to assess the association between exposure to air pollution during pregnancy and anthropometric measures at birth in a cohort in Valencia, Spain.

1 October 2014 in Environmental Research
Verified
Journal Article
Closed access
MRMIGUEL RODRIGUEZ-BARRANCO
MIGUEL RODRIGUEZ-BARRANCO
MLMarina Lacasaña
Marina Lacasaña
FGFernando Gil
Fernando Gil
JMJose Andres Lorca Marín
Jose Andres Lorca Marín
JOJuan Alguacil Ojeda
Juan Alguacil Ojeda
CAClemente Aguilar-Garduño
Clemente Aguilar-Garduño

1 February 2010 in Toxicology and Applied Pharmacology
Verified
Journal Article
Closed access
MLMarina Lacasaña
Marina Lacasaña
ILInmaculada López-Flores
Inmaculada López-Flores
MRMIGUEL RODRIGUEZ-BARRANCO
MIGUEL RODRIGUEZ-BARRANCO
CAClemente Aguilar-Garduño
Clemente Aguilar-Garduño
JBJulia Blanco-Muñoz
Julia Blanco-Muñoz
MCMariano E. Cebrian
Mariano E. Cebrian

1 December 2015 in Environment International
Verified
Journal Article
Closed access
BGBeatriz González-Alzaga
Beatriz González-Alzaga
AHAntonio Hernández
Antonio Hernández
MRMIGUEL RODRIGUEZ-BARRANCO
MIGUEL RODRIGUEZ-BARRANCO
IGInmaculada Gómez
Inmaculada Gómez
CAClemente Aguilar-Garduño
Clemente Aguilar-Garduño
MLMarina Lacasaña
Marina Lacasaña

24 August 2021 in Nature Communications
Verified
Journal Article
Open access
PDF file
TETodd M. Everson
Todd M. Everson
MVMarta Vives-Usano
Marta Vives-Usano
ESEmie Seyve
Emie Seyve
ACAndres Cardenas
Andres Cardenas
MLMarina Lacasaña
Marina Lacasaña
MBMariona Bustamante
Mariona Bustamante
Maternal smoking during pregnancy (MSDP) contributes to poor birth outcomes, in part through disrupted placental functions, which may be reflected in the placental epigenome. Here we present a meta-analysis of the associations between MSDP and placental DNA methylation (DNAm) and between DNAm and birth outcomes within the Pregnancy And Childhood Epigenetics (PACE) consortium (N = 1700, 344 with MSDP). We identify 443 CpGs that are associated with MSDP, of which 142 associated with birth outcomes, 40 associated with gene expression, and 13 CpGs are associated with all three. Only two CpGs have consistent associations from a prior meta-analysis of cord blood DNAm, demonstrating substantial tissue-specific responses to MSDP. The placental MSDP-associated CpGs are enriched for environmental response genes, growth-factor signaling, and inflammation, which play important roles in placental function. We demonstrate links between placental DNAm, MSDP and poor birth outcomes, which may better inform the mechanisms through which MSDP impacts placental function and fetal growth.