Nanofluid is a colloidal mixture consisting of nano-sized particles dispersed in a liquid medium. It improves heat transfer properties and promotes high energy efficiency in a wide spectrum of engineering applications. In recent years, particularly in the automotive industry, the addition of nanofluid in diesel/biodiesel as an additive for ICE has become an attractive approach to promote enhanced combustion efficiency and emission reduction due to their superior thermophysical properties. Many researchers have previously demonstrated that the addition of nanoparticles in diesel/biodiesel fuel improved the overall engine combustion characteristics. As a whole, this study aims to summarize the recent research findings related to the effect of nanoparticles on the fuel properties and engine combustion efficiency. Furthermore, different types of additive blended with varying fuel properties are also compared and discussed. Lastly, the advantages and prospects of using nanofluid as an additive fuel are summarized for future research opportunities.

Microchannel heat sink (MCHS) is an advanced cooling technique to fulfil the cooling demand for electronic devices installed with high-power integrated circuit packages (microchips). Various microchannel designs have been innovated to improve the heat transfer performance in an MCHS. Specifically, the utilisation of nanotechnology in the form of nanofluid in an MCHS attracted the attention of researchers because of considerable enhancement of thermal conductivity in nanofluid even at a low nanoparticle concentration. However, a high-pressure drop was the main limitation as it controls the MCHS performance resulted from heat transfer augmentation. Therefore, this study aimed to critically summarise the challenges and limitations of both single and hybrid passive methods of MCHS. Furthermore, the performance of nanofluid as a coolant in the MCHS as affected by the type and concentration of nanoparticle and the type of base fluid was reviewed systematically. The review indicated that the hybrid MCHS provides a better cooling performance than MCHS with the single passive method as the former results in a higher heat transfer rate with minimal pressure drop penalty. Besides that, further heat transfer performance can be enhanced by dispersing aluminium dioxide (Al ₂ O ₃ ) nanoparticles with a concentration of less than 2.0% (v/v) in the water-based coolant.

Cellulose and chitosan with remarkable biocompatibility and sophisticated physiochemical characteristics can be a new dawn to the advanced drug nano-carriers in cancer treatment. This study aims to synthesize layer-by-layer bionanocomposites from chitosan and rice straw cellulose encapsulated 5-Fluorouracil (CS-CF/5FU BNCs) using the ionic gelation method and the sodium tripolyphosphate (TPP) cross-linker. Data from X-ray and Fourier-transform infrared spectroscopy showed successful preparation of CS-CF/5FU BNCs. Based on images of scanning electron microscopy, 48.73 ± 1.52 nm was estimated for an average size of the bionanocomposites as spherical chitosan nanoparticles mostly coated rod-shaped cellulose reinforcement. 5-Fluorouracil indicated an increase in thermal stability after its encapsulation in the bionanocomposites. The drug encapsulation efficiency was found to be 86 ± 2.75%. CS-CF/5FU BNCs triggered higher drug release in a media simulating the colorectal fluid with pH 7.4 (76.82 ± 1.29%) than the gastric fluid with pH 1.2 (42.37 ± 0.43%). In in vitro cytotoxicity assays, cellulose fibers, chitosan nanoparticles and the bionanocomposites indicated biocompatibility towards CCD112 normal cells. Most promisingly, CS-CF/5FU BNCs at 250 µg/mL concentration eliminated 56.42 ± 0.41% of HCT116 cancer cells and only 8.16 ± 2.11% of CCD112 normal cells. Therefore, this study demonstrates that CS-CF/5FU BNCs can be considered as an eco-friendly and innovative nanodrug candidate for potential colorectal cancer treatment.