Purpose C-reactive protein (CRP) is a marker of chronic systemic inflammation frequently used in cardiovascular disease risk assessment. The purpose of this meta-analysis was to provide a quantitative estimate of the magnitude of change in CRP following participation in physical exercise interventions. Methods All studies included in the meta-analysis were peer reviewed and published in English. Human participants were assigned to a non-exercise comparison group or exercise training group, with the intervention lasting ≥2 weeks. CRP levels were measured at baseline, during and/or after completion of the exercise training programme. Random-effects models were used to aggregate a mean effect size (ES), 95% CIs and potential moderators. Results 83 randomised and non-randomised controlled trials met the inclusion criteria and resulted in 143 effects (n=3769). The mean ES of 0.26 (95% CI 0.18 to 0.34, p<0.001) indicated a decrease in CRP following exercise training. A decrease in body mass index (BMI; β=1.20, SE=0.25, p<0.0001) and %Fat (β=0.76, SE=0.21, p=0.0002) were associated with a decrease in CRP, independently accounting for 11.1% and 6.6% of the variation in response, respectively. Exercise training led to a greater reduction in CRP when accompanied by a decrease in BMI (ES=0.38, 95% CI 0.26 to 0.50); however, a significant improvement in CRP occurred in the absence of weight loss (ES=0.19, 95% CI 0.10 to 0.28; both p<0.001). Conclusions These results suggest that engaging in exercise training is associated with a decrease in CRP levels regardless of the age or sex of the individual; however, greater improvements in CRP level occur with a decrease in BMI or %Fat.

The primary aim of this study was to determine the association between body composition and performance outcomes in youth soccer players. Twenty-five competitive male youth soccer players (age = 13.7 ± 0.8 years, height = 167.4 ± 9.7 cm, weight = 57.6 ± 12.1 kg) volunteered to participate in this study. Height and weight were used to calculate body mass index (BMI). Body fat percentage (BF%) and fat-free mass (FFM) were determined with dual-energy X-ray absorptiometry. Each athlete performed the Pacer test, vertical jump, and t-test drill. Participants were predominantly normal weight (20.4 ± 2.7 kg·m⁻²). The body composition results were 20.3 ± 4.9% for BF% and 46.5 ± 8.7 kg for FFM. The results of the performance tests indicated a mean ± standard deviation (SD) of 1418 ± 332 m for Pacer, 57.2 ± 7.4 cm for vertical jump, 11.6 ± 0.7 s for t-test. Body mass index was not associated with any performance measure (r = 0.02 to −0.21, all p > 0.05). Body fat percentage was associated with the Pacer, vertical jump, and t-test (r = −0.62, −0.57, 0.61, respectively; all p < 0.01) and remained after accounting for BMI. Fat-free mass was only significantly related to t-test (r = −0.43, p < 0.01). However, after controlling for BMI, FFM was related to all three performance tests. Body fat percentage and FFM are associated with performance in youth soccer players, with stronger relationships reported in the former metric. The findings highlight the need for accurate body composition measurements as part of an assessment battery in young athletes.

Delayed onset muscle soreness (DOMS) is a symptom of exercise-induced muscle damage that occurs following exercise. Previous research has indicated that branched-chain amino acid (BCAA) supplementation may attenuate exercise-induced muscle damage that causes delayed onset muscle soreness, however the results are inconsistent. The primary aim of this study was to examine the previous literature assessing the effect of BCAA supplementation on DOMS following an acute bout of exercise in adults. This review was conducted in accordance with PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-analyses), and identified peer-reviewed articles comparing a BCAA supplement to a placebo non-BCAA supplement following an acute bout of exercise. An electronic search of three databases (EbscoHost, Web of Science, and SPORTDiscus) yielded 42 articles after duplicates were removed. All studies included in the current analyis were: 1) peer-reviewed publications; 2) available in English; 3) utilized a random control design that compared a BCAA group to a placebo control group following exercise; 4) and assessed soreness of muscle tissue during recovery. DOMS was assessed in 61 participants following ingestion of a BCAA supplement over the course of these interventions. The cumulative results of 37 effects gathered from 8 studies published between 2007 and 2017 indicated that BCAA supplementation reduced DOMS following exercise training (ES = 0.7286, 95% CI: 0.5017 to 0.9555, p < 0.001). A large decrease in DOMS occurs following BCAA supplementation after exercise compared to a placebo supplement.