El objetivo fue analizar las características de las unidades de producción familiar ovina de dos municipios de la Mixteca Oaxaqueña teniendo como referencia el sistema de producción, acceso al mercado y el uso del territorio. Se usó una metodología mixta, empleando un cuestionario estructurado donde se analizaron variables de carácter socioeconómico y productivo; y observación participativa en 29 ovinocultores familiares. Los resultados señalan que el 100 % de los productores ven a la ovinocultura como principal fuente de ingresos, 86 % produce bajo un sistema de subsistencia, 100 % emplea la mano de obra familiar, la estrategia alimentaria principal es el pastoreo debido a las características del territorio y el tipo de tenencia de la tierra comunal en un 90 %, la función zootécnica es producción de carne destinada al comercio local y autoconsumo, 83 % de los productores cuentan con corral de encierro construido con material de la región, 86.7 % de los productores mantienen su corral dentro del predio familiar, se aplican escasas medidas de manejo y sanitarias. El análisis de los sistemas productivos permitió identificar formas de gestión de su producción la cual está ligada a los servicios dentro de su territorio, desarrollando una producción de tipo familiar que cumple con funciones económicas, sociales, ambientales y culturales, sin embargo, se cuenta con una baja productividad. Por lo cual, se considera necesario la adopción de tecnología e innovación a través de estrategias y políticas públicas que impulsen el desarrollo rural en zonas marginales tendientes a disminuir el nivel de pobreza e inseguridad alimentaria.

Creole sheep in México have undergone crossbreeding, provoking the loss of genetic variability. The objective of the present study is to determine the intra-racial genetic diversity, the genetic relationship with other genotypes, and the populational substructure of the Oaxacan Creole sheep. Twenty-nine blood samples were obtained of Creole sheep of the Oaxaca Mixteca region in México. A genetic analysis was made with 41 microsatellites recommended for studies of genetic diversity in sheep. An analysis was made of genetic diversity, populational structure, and genetic distance with 27 other sheep populations. The study found 205 alleles with a range of 2 to 9 by locus and an effective number of 3.33. The intra-racial analysis showed a moderate genetic diversity with values of expected heterozygosity of 0.686 and observed of 0.756, a mean polymorphic information content of 0.609, and a mean coefficient of consanguinity of −0.002. In interracial genetic diversity for the coefficients of consanguinity, the values were F_IS = 0.0774, F_IT = 0.16993, and F_ST = 0.10028, showing an elevated genetic distance with other creole breeds, but close to Argentine Creole, to another Creole of México and the Spanish Merino. Its genetic structure showed that it does not have any populational subdivision nor mixes with the others analyzed. It is concluded that it is a distinct and isolated population and is proposed as the creole breed “Chocholteca” for its conservation.

A study determining microsatellite markers was conducted to compare similarities among three different populations of Macrobrachium tenellum prawns from three different hydrological basins in Oaxaca, Mexico. In total, nine different markers in the population were used, of which six coded for the three populations and three did not. Although different, the three populations are closely genetically related, with an average allele richness from 6.845 to 16.754 and a heterozygosity of 0.166 to 0.264. However, the relationship could be much closer, particularly between them. The possible applications and scope of this knowledge are commented on and discussed.

Host defense peptides (HDPs), ancestral effectors of innate immunity, have emerged as pleiotropic regulators transcending their antimicrobial origins. This review critically examines the complex interplay among HDPs, hemostasis, and tissue repair. We analyze molecular mechanisms governing interactions with platelets and endothelial cells, highlighting a fundamental paradigm shift: platelets and megakaryocytes are active synthesizers of a specific peptide repertoire rather than passive carriers. Functional dualities are elucidated, contrasting LL-37-driven platelet agonism via glycoprotein VI (GPVI) against the amyloid-like stabilization of fibrin by defensins. Based on these mechanisms, we propose a framework wherein HDPs function as concentration-dependent molecular switches between physiological repair and pathological thromboinflammation. Furthermore, the review addresses the hypothesis of “adaptive thrombopoiesis,” where systemic peptide surges act as danger signals to reprogram the function of newly formed platelets. Finally, therapeutic implications are evaluated, emphasizing the design of protease-resistant peptidomimetics to harness protective effects while mitigating vascular toxicity.