This page has only limited features, please log in for full access.

Unclaimed
Chalermpong Saenjum
Center of Excellence for Innovation in Analytical Science and Technology (I-ANALY-S-T), Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand

Basic Info

Basic Info is private.

Honors and Awards

The user has no records in this section


Career Timeline

The user has no records in this section.


Short Biography

The user biography is not available.
Following
Followers
Co Authors
The list of users this user is following is empty.
Following: 0 users

Feed

Journal article
Published: 29 August 2021 in Molecules
Reads 0
Downloads 0

Five glutinous purple rice cultivars and non-glutinous purple rice cultivated in different altitudes in the north of Thailand were collected. The samples were extracted using ethanol and determined for anthocyanins using HPLC. The total phenolic content (TPC), total flavonoid content (TFC), and the antioxidant, anti-inflammatory, and antimicrobial activities against foodborne pathogens were investigated. The highland glutinous cultivar named Khao’ Gam Luem-Phua (KGLP) extract had significantly high levels of cyanidin 3-O-glucoside, peonidin 3-O-glucoside, delphinidin 3-O-glucoside, TPC, and TFC, as well as exerting a potent antioxidant activity through ABTS assay (524.26 ± 4.63 VCEAC, mg l-ascorbic/g extract), lipid peroxidation (IC50 = 19.70 ± 0.31 µg/mL), superoxide anions (IC50 = 11.20 ± 0.25 µg/mL), nitric oxide (IC50 = 17.12 ± 0.56 µg/mL), a suppression effect on nitric oxide (IC50 = 18.32 ± 0.82 µg/mL), and an inducible nitric oxide synthase production (IC50 = 23.43 ± 1.21 µg/mL) in combined lipopolysaccharide-interferon-γ-activated RAW 264.7 murine macrophage cells. Additionally, KGLP also exhibited antimicrobial activity against foodborne pathogens, Staphylococcus aureus, Escherichia coli, Salmonella Enteritidis, and Vibrio parahaemolyticus. These results indicate that Thai glutinous purple rice cultivated on the highland could be a potent natural source of antioxidants, anti-inflammatories, and antimicrobial agents for use as a natural active pharmaceutical ingredient in functional food and nutraceutical products.

ACS Style

Thanawat Pattananandecha; Sutasinee Apichai; Sasithorn Sirilun; Jakaphun Julsrigival; Kasirawat Sawangrat; Fumihiko Ogata; Naohito Kawasaki; Busaban Sirithunyalug; Chalermpong Saenjum. Anthocyanin Profile, Antioxidant, Anti-Inflammatory, and Antimicrobial against Foodborne Pathogens Activities of Purple Rice Cultivars in Northern Thailand. Molecules 2021, 26, 5234 .

AMA Style

Thanawat Pattananandecha, Sutasinee Apichai, Sasithorn Sirilun, Jakaphun Julsrigival, Kasirawat Sawangrat, Fumihiko Ogata, Naohito Kawasaki, Busaban Sirithunyalug, Chalermpong Saenjum. Anthocyanin Profile, Antioxidant, Anti-Inflammatory, and Antimicrobial against Foodborne Pathogens Activities of Purple Rice Cultivars in Northern Thailand. Molecules. 2021; 26 (17):5234.

Chicago/Turabian Style

Thanawat Pattananandecha; Sutasinee Apichai; Sasithorn Sirilun; Jakaphun Julsrigival; Kasirawat Sawangrat; Fumihiko Ogata; Naohito Kawasaki; Busaban Sirithunyalug; Chalermpong Saenjum. 2021. "Anthocyanin Profile, Antioxidant, Anti-Inflammatory, and Antimicrobial against Foodborne Pathogens Activities of Purple Rice Cultivars in Northern Thailand." Molecules 26, no. 17: 5234.

Journal article
Published: 11 August 2021 in Plants
Reads 0
Downloads 0

The current study investigated the inhibiting effect on reactive oxygen species (ROS), reactive nitrogen species (RNS), and matrix metalloproteinase-1 (MMP-1) production in a cell-based study of standardized rosmarinic acid enriched extract (SRAEE) prepared from Thunbergia laurifolia leaves. HPLC chromatogram revealed that rosmarinic acid is a major component in prepared SRAEE, followed by caffeic acid. SRAEE exhibited antioxidant activity both in vitro and cell-based studies. SRAEE showed scavenging effects on nitric oxide and superoxide anion and inhibition effects on lipid peroxidation in vitro. SRAEE also inhibited ROS and MMP-1 production in normal human dermal fibroblast cells induced by H2O2 and UVA, respectively, without exerted cytotoxicity. Additionally, collagen degradation was protected by SRAEE induced by UVA. Nitric oxide and inducible nitric oxide synthase (iNOS) productions were also inhibited by SRAEE in RAW264.7 mouse macrophage cells induced by combined lipopolysaccharide (LPS)-interferon-γ (IFN-γ). The results indicated that SRAEE is a potential candidate as a natural pharmaceutical active ingredient for cosmeceutical product application.

ACS Style

Thanawat Pattananandecha; Sutasinee Apichai; Jakaphun Julsrigival; Malyn Ungsurungsie; Suched Samuhasaneetoo; Pat Chulasiri; Pakakrong Kwankhao; Supaporn Pitiporn; Fumihiko Ogata; Naohito Kawasaki; Chalermpong Saenjum. Antioxidant Activity and Anti-Photoaging Effects on UVA-Irradiated Human Fibroblasts of Rosmarinic Acid Enriched Extract Prepared from Thunbergia laurifolia Leaves. Plants 2021, 10, 1648 .

AMA Style

Thanawat Pattananandecha, Sutasinee Apichai, Jakaphun Julsrigival, Malyn Ungsurungsie, Suched Samuhasaneetoo, Pat Chulasiri, Pakakrong Kwankhao, Supaporn Pitiporn, Fumihiko Ogata, Naohito Kawasaki, Chalermpong Saenjum. Antioxidant Activity and Anti-Photoaging Effects on UVA-Irradiated Human Fibroblasts of Rosmarinic Acid Enriched Extract Prepared from Thunbergia laurifolia Leaves. Plants. 2021; 10 (8):1648.

Chicago/Turabian Style

Thanawat Pattananandecha; Sutasinee Apichai; Jakaphun Julsrigival; Malyn Ungsurungsie; Suched Samuhasaneetoo; Pat Chulasiri; Pakakrong Kwankhao; Supaporn Pitiporn; Fumihiko Ogata; Naohito Kawasaki; Chalermpong Saenjum. 2021. "Antioxidant Activity and Anti-Photoaging Effects on UVA-Irradiated Human Fibroblasts of Rosmarinic Acid Enriched Extract Prepared from Thunbergia laurifolia Leaves." Plants 10, no. 8: 1648.

Journal article
Published: 11 August 2021 in Molecules
Reads 0
Downloads 0

Guanidinyl tryptophan derivatives TGN1, TGN2, TGN3, and TGN4 were synthesized, and these compounds were shown to possess in vitro inhibitory activity for amyloid aggregation in a previous study. Nevertheless, the influence of the TGN series of compounds on the binding and permeation behaviors of an Aβ monomer to the cell membranes was not elucidated. In this study, we investigated the effect of compounds in the TGN series on the behavior of an Aβ monomer regarding its toxicity toward the bilayer lipid membrane using molecular dynamics (MD) simulation. MD simulations suggest that TGN4 is a potential agent that can interfere with the movement of the Aβ monomer into the membrane. The MM-GBSA result demonstrated that TGN4 exhibits the highest affinity to the Aβ1–42 monomer but has the lowest affinity to the bilayer. Moreover, TGN4 also contributes to a decrease in the binding affinity between the Aβ1–42 monomer and the POPC membrane. Regarding the results of the binding mode and conformational analyses, a high number of amino-acid residues were shown to provide the binding interactions between TGN4 and the Aβ1–42 monomer. TGN4 also reduces the conformational transition of the Aβ1–42 monomer by means of interacting with the monomer. The present study presents molecular-level insights into how the TGN series of compounds affect the membrane adsorption and the conformational transition of the Aβ1–42 monomer, which could be valuable for the further development of new anti-Alzheimer agents.

ACS Style

Pathomwat Wongrattanakamon; Jutamas Jiaranaikulwanitch; Opa Vajragupta; Supat Jiranusornkul; Chalermpong Saenjum; Wipawadee Yooin. Potential Anti-Alzheimer Agents from Guanidinyl Tryptophan Derivatives with Activities of Membrane Adhesion and Conformational Transition Inhibitions. Molecules 2021, 26, 4863 .

AMA Style

Pathomwat Wongrattanakamon, Jutamas Jiaranaikulwanitch, Opa Vajragupta, Supat Jiranusornkul, Chalermpong Saenjum, Wipawadee Yooin. Potential Anti-Alzheimer Agents from Guanidinyl Tryptophan Derivatives with Activities of Membrane Adhesion and Conformational Transition Inhibitions. Molecules. 2021; 26 (16):4863.

Chicago/Turabian Style

Pathomwat Wongrattanakamon; Jutamas Jiaranaikulwanitch; Opa Vajragupta; Supat Jiranusornkul; Chalermpong Saenjum; Wipawadee Yooin. 2021. "Potential Anti-Alzheimer Agents from Guanidinyl Tryptophan Derivatives with Activities of Membrane Adhesion and Conformational Transition Inhibitions." Molecules 26, no. 16: 4863.

Journal article
Published: 28 July 2021 in Minerals
Reads 0
Downloads 0

The characteristics of acid-activated raw bentonite (RB) activated with binary acid solutions sulfuric acid + nitric acid, nitric acid + phosphoric acid, and phosphoric acid + sulfuric acid, at a concentration of 5 mol/L (denoted as 5-SN, 5-NP, and 5-PS), were evaluated. Moreover, its application for improving the electrical conductivity in tap water was demonstrated. Acid activation induced the partial destruction of RB; subsequently, there was a significant release of sodium ions from the RB. In addition, the specific surface area and pore volume of 5-SN, 5-NP, and 5-PS were higher than those of RB. Next, the electrical conductivity when using RB increased with adsorption treatment because sodium ions were released from the RB. However, the electrical conductivity significantly decreased with adsorption treatment when using acid-activated RB. Specifically, magnesium ions, calcium ions, and potassium ions were removed into 5-SN, 5-NP, and 5-PS, and sodium ions were not released from the RB simultaneously. The removal percentage of the electrical conductivity using 5-SN, 5-NP, and 5-PS was approximately 31% to 36%. The results indicated that employing acid-activated RB with a binary acid solution is a useful method for decreasing the electrical conductivity in tap water.

ACS Style

Eri Nagahashi; Fumihiko Ogata; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. Preparation and Characterization of Acid-Activated Bentonite with Binary Acid Solution and Its Use in Decreasing Electrical Conductivity of Tap Water. Minerals 2021, 11, 815 .

AMA Style

Eri Nagahashi, Fumihiko Ogata, Chalermpong Saenjum, Takehiro Nakamura, Naohito Kawasaki. Preparation and Characterization of Acid-Activated Bentonite with Binary Acid Solution and Its Use in Decreasing Electrical Conductivity of Tap Water. Minerals. 2021; 11 (8):815.

Chicago/Turabian Style

Eri Nagahashi; Fumihiko Ogata; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. 2021. "Preparation and Characterization of Acid-Activated Bentonite with Binary Acid Solution and Its Use in Decreasing Electrical Conductivity of Tap Water." Minerals 11, no. 8: 815.

Journal article
Published: 26 July 2021 in Plants
Reads 0
Downloads 0

A modern chemical sensor system (M-CSS) was developed for the cost-effective chemical analysis of Thai precision and sustainable agriculture (TPSA), which is suitable in rural Thailand and elsewhere. The aim of this study was to achieve precision and sustainable agriculture (P-SA). The M-CSS functions according to the International Union of Pure and Applied Chemistry (IUPAC) definition and incorporates information and communication technologies (ICTs). The developed chemical sensor in the M-CSS is based on a colorimetric determination by a smart device/smartphone. Additionally, the preparation of soil samples was investigated. Soil samples of optimal conditions were extracted using an acid extractant in the ratio of one to two (extract to soil sample). Then, phosphate-phosphorous and potassium were detected with the M-CSS, which showed an excellent correlation with the standard reference methods. Interestingly, it is noteworthy that the at-site analysis of the developed method could detect a greater nitrate-nitrogen content than that of the standard reference method. The developed cost-effective analysis for the plant macronutrient content in the soil, including nitrate-nitrogen, phosphate-phosphorous, and potassium, was demonstrated for organic vegetable farms at the real P-SA research site in Northern Thailand. The obtained results can guide the management of the application of fertilizers. The proposed M-CSS exhibited the potential to be used for at-site soil macronutrient analysis and represents the starting point of Thai precision and sustainable agriculture (TPSA).

ACS Style

Sutasinee Apichai; Chalermpong Saenjum; Thanawat Pattananandecha; Kitti Phojuang; Siraprapa Wattanakul; Kanokwan Kiwfo; Attachai Jintrawet; Kate Grudpan. Cost-Effective Modern Chemical Sensor System for Soil Macronutrient Analysis Applied to Thai Sustainable and Precision Agriculture. Plants 2021, 10, 1524 .

AMA Style

Sutasinee Apichai, Chalermpong Saenjum, Thanawat Pattananandecha, Kitti Phojuang, Siraprapa Wattanakul, Kanokwan Kiwfo, Attachai Jintrawet, Kate Grudpan. Cost-Effective Modern Chemical Sensor System for Soil Macronutrient Analysis Applied to Thai Sustainable and Precision Agriculture. Plants. 2021; 10 (8):1524.

Chicago/Turabian Style

Sutasinee Apichai; Chalermpong Saenjum; Thanawat Pattananandecha; Kitti Phojuang; Siraprapa Wattanakul; Kanokwan Kiwfo; Attachai Jintrawet; Kate Grudpan. 2021. "Cost-Effective Modern Chemical Sensor System for Soil Macronutrient Analysis Applied to Thai Sustainable and Precision Agriculture." Plants 10, no. 8: 1524.

Journal article
Published: 19 July 2021 in Antioxidants
Reads 0
Downloads 0

The study investigated the impact of the fermentation process on the phenolic contents and antioxidant and anti-inflammatory activities in extracts of Miang, an ethnic fermented tea product of northern Thailand. The acetone (80%) extraction of Miang samples fermented by a non-filamentous fungi-based process (NFP) and filamentous fungi-based process (FFP) had elevated levels of total polyphenols, total tannins, and condensed tannins compared to young and mature tea leaves. The antioxidant studies also showed better the half-maximal inhibitory concentration (IC50) values for fermented leaves in both 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity assays as well as improved ferric reducing antioxidant power (FRAP) compared to young and mature tea leaves. Extracts of NFP and FFP samples at concentrations of 50 and 100 ppm showed better protective effects against hydrogen peroxide (H2O2)-induced intracellular reactive oxygen species (ROS) production in HT-29 colorectal cells without exerting cytotoxicity. Additionally, lipopolysaccharide (LPS)-induced production of nitric oxide (a proinflammatory mediator as well as a reactive nitrogen species) was also inhibited by these fermented Miang extracts with an IC50 values of 17.15 μg/mL (NFP), 20.17 μg/mL (FFP), 33.96 μg/mL (young tea leaves), and 31.33 μg/mL (mature tea leaves). Therefore, both NFP-Miang and FFP-Miang showed the potential to be targeted as natural bioactive functional ingredients with preventive properties against free radical and inflammatory-mediated diseases.

ACS Style

Aliyu Abdullahi; Pratthana Kodchasee; Kridsada Unban; Thanawat Pattananandecha; Chalermpong Saenjum; Apinun Kanpiengjai; Kalidas Shetty; Chartchai Khanongnuch. Comparison of Phenolic Contents and Scavenging Activities of Miang Extracts Derived from Filamentous and Non-Filamentous Fungi-Based Fermentation Processes. Antioxidants 2021, 10, 1144 .

AMA Style

Aliyu Abdullahi, Pratthana Kodchasee, Kridsada Unban, Thanawat Pattananandecha, Chalermpong Saenjum, Apinun Kanpiengjai, Kalidas Shetty, Chartchai Khanongnuch. Comparison of Phenolic Contents and Scavenging Activities of Miang Extracts Derived from Filamentous and Non-Filamentous Fungi-Based Fermentation Processes. Antioxidants. 2021; 10 (7):1144.

Chicago/Turabian Style

Aliyu Abdullahi; Pratthana Kodchasee; Kridsada Unban; Thanawat Pattananandecha; Chalermpong Saenjum; Apinun Kanpiengjai; Kalidas Shetty; Chartchai Khanongnuch. 2021. "Comparison of Phenolic Contents and Scavenging Activities of Miang Extracts Derived from Filamentous and Non-Filamentous Fungi-Based Fermentation Processes." Antioxidants 10, no. 7: 1144.

Journal article
Published: 01 July 2021 in Sustainability
Reads 0
Downloads 0

Miang or fermented tea leaf has been a part of the Mae Kampong community, one of northern Thailand’s famous tourist attractions, for a long time. Although the demand and popularity of Miang are decreasing, Miang is still important to the community lifestyle in various ways. Thus, this study aimed to investigate Miang consumption behavior, lifestyle, and wisdom in the Mae Kampong community, which would lead to sustainable development. The study involved a cross-sectional survey and a qualitative study. The research was done in Mae Kampong Village, Mae On District, Chiang Mai, Thailand. A total of 335 participants participated; 60.9% were female with an average age of 61.3 ± 12.2 years old. In all, 93.7% of the participants consumed Miang daily, mostly as a snack (86.5%). Consuming Miang as a staple food and beverage were less common. Furthermore, only 2.5% of the participants considered Miang as medicine. Miang is also the primary source of income and a tourist attraction. Additionally, Miang is an item in religious and local rituals. The Miang culture and the local lifestyle are bonded deeply as a sustainable economy, society, and environment. The wisdom in Miang culture encourages a better quality of life for the Mae Kampong community.

ACS Style

Dujrudee Chinwong; Panchana Charaj; Piyatida Panitsupakamol; Tamonwan Chankaew; Surarong Chinwong; Chalermpong Saenjum. Local Wisdom of Miang Lifestyle and Community for Sustainable Development in Northern Thailand. Sustainability 2021, 13, 7381 .

AMA Style

Dujrudee Chinwong, Panchana Charaj, Piyatida Panitsupakamol, Tamonwan Chankaew, Surarong Chinwong, Chalermpong Saenjum. Local Wisdom of Miang Lifestyle and Community for Sustainable Development in Northern Thailand. Sustainability. 2021; 13 (13):7381.

Chicago/Turabian Style

Dujrudee Chinwong; Panchana Charaj; Piyatida Panitsupakamol; Tamonwan Chankaew; Surarong Chinwong; Chalermpong Saenjum. 2021. "Local Wisdom of Miang Lifestyle and Community for Sustainable Development in Northern Thailand." Sustainability 13, no. 13: 7381.

Journal article
Published: 10 June 2021 in Molecules
Reads 0
Downloads 0

In this study, we investigated the antioxidant and anti-inflammatory phytochemicals and paramagnetic species in dragon fruit using high-performance liquid chromatography (HPLC) and electron paramagnetic resonance (EPR). HPLC analysis demonstrated that dragon fruit is enriched with bioactive phytochemicals, with significant variations between each part of the fruit. Anthocyanins namely, cyanidin 3-glucoside, delphinidin 3-glucoside, and pelargonidin 3-glucoside were detected in the dragon fruit peel and fresh red pulp. Epicatechin gallate, epigallocatechin, caffeine, and gallic acid were found in the dragon fruit seed. Additionally, 25–100 mg × L−1 of dragon fruit pulp and peel extracts containing enrichment of cyanidin 3-glucoside were found to inhibit the production of reactive oxygen species (ROS), reactive nitrogen species (RNS), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) in cell-based studies without exerted cytotoxicity. EPR primarily detected two paramagnetic species in the red samples. These two different radical species were assigned as stable radicals and Mn2+ (paramagnetic species) based on the g-values and hyperfine components. In addition, the broad EPR line width of the white peel can be correlated to a unique moiety in dragon fruit. Our EPR and HPLC results provide new insight regarding the phytochemicals and related stable intermediates found in various parts of dragon fruit. Thus, we suggest here that there is the potential to use dragon fruit peel, which contains anthocyanins, as a natural active pharmaceutical ingredient.

ACS Style

Chalermpong Saenjum; Thanawat Pattananandecha; Kouichi Nakagawa. Antioxidative and Anti-Inflammatory Phytochemicals and Related Stable Paramagnetic Species in Different Parts of Dragon Fruit. Molecules 2021, 26, 3565 .

AMA Style

Chalermpong Saenjum, Thanawat Pattananandecha, Kouichi Nakagawa. Antioxidative and Anti-Inflammatory Phytochemicals and Related Stable Paramagnetic Species in Different Parts of Dragon Fruit. Molecules. 2021; 26 (12):3565.

Chicago/Turabian Style

Chalermpong Saenjum; Thanawat Pattananandecha; Kouichi Nakagawa. 2021. "Antioxidative and Anti-Inflammatory Phytochemicals and Related Stable Paramagnetic Species in Different Parts of Dragon Fruit." Molecules 26, no. 12: 3565.

Journal article
Published: 12 April 2021 in Sustainability
Reads 0
Downloads 0

The feasibility of using potassium-type zeolite (K-type zeolite) prepared from coal fly ash (CFA) for the removal of Hg2+ from aqueous media and the adsorption/desorption capabilities of various potassium-type zeolites were assessed in this study. Potassium-type zeolite samples were synthesized by hydrothermal treatment of CFA at different intervals (designated CFA, FA1, FA3, FA6, FA12, FA24, and FA48, based on the hours of treatment) using potassium hydroxide solution, and their physicochemical characteristics were evaluated. Additionally, the quantity of Hg2+ adsorbed was in the order CFA, FA1 < FA3 < FA6 < FA12 < FA24 < FA48, in the current experimental design. Therefore, the hydrothermal treatment time is important to enhance the adsorption capability of K-type zeolite. Moreover, the effects of pH, temperature, contact time, and coexistence on the adsorption of Hg2+ were elucidated. In addition, Hg2+ adsorption mechanism using FA48 was demonstrated. Our results indicated that Hg2+ was exchanged with K+ in the interlayer of FA48 (correlation coefficient = 0.946). Finally, adsorbed Hg2+ onto FA48 could be desorbed using a sodium hydroxide solution (desorption percentage was approximately 70%). Our results revealed that FA48 could be a potential adsorbent for the removal of Hg2+ from aqueous media.

ACS Style

Yuhei Kobayashi; Fumihiko Ogata; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. Adsorption/Desorption Capability of Potassium-Type Zeolite Prepared from Coal Fly Ash for Removing of Hg2+. Sustainability 2021, 13, 4269 .

AMA Style

Yuhei Kobayashi, Fumihiko Ogata, Chalermpong Saenjum, Takehiro Nakamura, Naohito Kawasaki. Adsorption/Desorption Capability of Potassium-Type Zeolite Prepared from Coal Fly Ash for Removing of Hg2+. Sustainability. 2021; 13 (8):4269.

Chicago/Turabian Style

Yuhei Kobayashi; Fumihiko Ogata; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. 2021. "Adsorption/Desorption Capability of Potassium-Type Zeolite Prepared from Coal Fly Ash for Removing of Hg2+." Sustainability 13, no. 8: 4269.

Journal article
Published: 21 February 2021 in Water
Reads 0
Downloads 0

To evaluate the feasibility of nickel–aluminum (the Ni2+:Al3+ molar ratios of 1.0:1.0 and 1.0:2.0 are denoted as NA11 and NA12, respectively) and nickel–aluminum–zirconium type (the Ni2+:Al3+:Zr4+ molar ratios of 0.9:1.0:0.09 and 0.9:2.0:0.09 are denoted as NAZ1 and NAZ2, respectively) hydroxides for Cr(VI) removal from aqueous media, the adsorption capability and adsorption mechanism of Cr(VI) using the above-mentioned adsorbents were investigated in this study. The quantity of Cr(VI) adsorbed onto NA11, NA12, NAZ1, and NAZ2 was 25.5, 25.6, 24.1, and 24.6 mg g−1, respectively. However, the quantity of aluminum (base metal) released from NA11 (approximately 0.14 mg g−1) was higher than that from NAZ1 (approximately 1.0 µg g−1), indicating that NAZ1 was more suitable for Cr(VI) removal than NA11. In addition, the effects of pH, contact time, and temperature on the adsorption of Cr(VI) were evaluated. Moreover, to elucidate the adsorption mechanism of Cr(VI) using NA11 and NAZ1, the elemental distribution, X-ray photoelectron spectrometry spectra, and ion exchange capability were also determined. Cr(VI) adsorbed onto the NAZ1 surface was easily desorbed using a sodium hydroxide solution under our experimental conditions. The information regarding this study can be useful for removing Cr(VI) from aqueous media.

ACS Style

Fumihiko Ogata; Noriaki Nagai; Ayako Tabuchi; Megumu Toda; Masashi Otani; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. Evaluation of Adsorption Mechanism of Chromium(VI) Ion Using Ni-Al Type and Ni-Al-Zr Type Hydroxides. Water 2021, 13, 551 .

AMA Style

Fumihiko Ogata, Noriaki Nagai, Ayako Tabuchi, Megumu Toda, Masashi Otani, Chalermpong Saenjum, Takehiro Nakamura, Naohito Kawasaki. Evaluation of Adsorption Mechanism of Chromium(VI) Ion Using Ni-Al Type and Ni-Al-Zr Type Hydroxides. Water. 2021; 13 (4):551.

Chicago/Turabian Style

Fumihiko Ogata; Noriaki Nagai; Ayako Tabuchi; Megumu Toda; Masashi Otani; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. 2021. "Evaluation of Adsorption Mechanism of Chromium(VI) Ion Using Ni-Al Type and Ni-Al-Zr Type Hydroxides." Water 13, no. 4: 551.

Journal article
Published: 17 February 2021 in Antioxidants
Reads 0
Downloads 0

The aim of this study is to determine antioxidant and anti-inflammatory activities relating to the antiosteoporosis effects of various perilla seed meal (PSM) fractions. The remaining waste of perilla seed obtained from cold oil compression was extracted with 70% ethanol and sequentially fractionated according to solvent polarity with hexane, dichloromethane, ethyl acetate, and water. The results indicated that the seed-meal ethyl acetate fraction (SMEF) exhibited the highest antioxidant and anti-inflammatory activities, and rosmarinic acid (RA) content. The signaling pathways induced by the receptor activator of the nuclear factor kappa B (NF-κB) ligand (RANKL) that trigger reactive oxygen species (ROS) and several transcription factors, leading to the induction of osteoclastogenesis, were also investigated. The SMEF clearly showed attenuated RANKL-induced tartrate-resistant acid phosphatase (TRAP)-positive multinucleated osteoclasts and TRAP activity. A Western blot analysis showed that the SMEF significantly downregulated RANKL-induced NF-κB, AP-1 activation, and the nuclear factor of activated T-cell 1 (NFATc1) expression. SMEF also suppressed RANKL-induced osteoclast-specific marker gene-like MMP-9 using zymography. Furthermore, the SMEF showed inhibition of RANKL-induced ROS production in RAW 264.7 cells. The results suggest that the SMEF, which contained high quantities of RA, could be developed as a natural active pharmaceutical ingredient for osteoclastogenic protection and health promotion.

ACS Style

Kanokkarn Phromnoi; Maitree Suttajit; Chalermpong Saenjum; Pornngarm Limtrakul (Dejkriengkraikul). Inhibitory Effect of a Rosmarinic Acid-Enriched Fraction Prepared from Nga-Mon (Perilla frutescens) Seed Meal on Osteoclastogenesis through the RANK Signaling Pathway. Antioxidants 2021, 10, 307 .

AMA Style

Kanokkarn Phromnoi, Maitree Suttajit, Chalermpong Saenjum, Pornngarm Limtrakul (Dejkriengkraikul). Inhibitory Effect of a Rosmarinic Acid-Enriched Fraction Prepared from Nga-Mon (Perilla frutescens) Seed Meal on Osteoclastogenesis through the RANK Signaling Pathway. Antioxidants. 2021; 10 (2):307.

Chicago/Turabian Style

Kanokkarn Phromnoi; Maitree Suttajit; Chalermpong Saenjum; Pornngarm Limtrakul (Dejkriengkraikul). 2021. "Inhibitory Effect of a Rosmarinic Acid-Enriched Fraction Prepared from Nga-Mon (Perilla frutescens) Seed Meal on Osteoclastogenesis through the RANK Signaling Pathway." Antioxidants 10, no. 2: 307.

Journal article
Published: 24 August 2020 in Water
Reads 0
Downloads 0

In this study, a novel zeolite (K-type zeolite) was synthesized from coal fly ash (FA), and adsorption capacity on Pb2+ was assessed. Six types of zeolite (FA1, FA3, FA6, FA12, FA24, and FA48) were prepared, and their physicochemical properties, such as surface functional groups, cation exchange capacity, pHpzc, specific surface area, and pore volume, were evaluated. The quantity of Pb2+ adsorbed by the prepared zeolites followed the order FA < FA1 < FA3 < FA6 < FA12 < FA24 < FA48. Current results indicate that the level of Pb2+ adsorbed was strongly related to the surface characteristics of the adsorbent. Additionally, the correlation coefficient between the amounts of Pb2+ adsorbed and K+ released from FA48 was 0.958. Thus, ion exchange with K+ in the interlayer of FA48 is critical for the removal of Pb2+ from aqueous media. The new binding energies of Pb(4f) at 135 and 140 eV were detected after adsorption. Moreover, FA48 showed selectivity for Pb2+ adsorption in binary solution systems containing cations. The results revealed that FA48 could be useful for removing Pb2+ from aqueous media.

ACS Style

Yuhei Kobayashi; Fumihiko Ogata; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. Removal of Pb2+ from Aqueous Solutions Using K-Type Zeolite Synthesized from Coal Fly Ash. Water 2020, 12, 2375 .

AMA Style

Yuhei Kobayashi, Fumihiko Ogata, Chalermpong Saenjum, Takehiro Nakamura, Naohito Kawasaki. Removal of Pb2+ from Aqueous Solutions Using K-Type Zeolite Synthesized from Coal Fly Ash. Water. 2020; 12 (9):2375.

Chicago/Turabian Style

Yuhei Kobayashi; Fumihiko Ogata; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. 2020. "Removal of Pb2+ from Aqueous Solutions Using K-Type Zeolite Synthesized from Coal Fly Ash." Water 12, no. 9: 2375.

Journal article
Published: 14 June 2020 in Water
Reads 0
Downloads 0

The technology of wastewater treatment involving removal of heavy metals using complex metal hydroxides is reported. In this study, complex nickel-aluminum (NA11 and NA12) and nickel-aluminum-zirconium (NAZ1 and NAZ2) hydroxides were prepared for the removal of arsenite ions, As(III), from aqueous solution. The characteristics of each adsorbent were evaluated, and the adsorption capacity and adsorption mechanism were determined. The adsorption capacity of As(III) on NAZ1 (15.3 mg g−1) was greater than that on NA11 (9.3 mg g−1). Coverage is directly related to the specific surface area with a correlation coefficient of 0.921. Ion exchange involving sulfate ions in the interlayer of the adsorbent also plays a role in the mechanism of As(III) adsorption as demonstrated by correlation coefficients of 0.797 and 0.944 for the NA11 and NAZ1, respectively. The results demonstrate the usefulness of NAZ1 in removing As(III) from aqueous media.

ACS Style

Fumihiko Ogata; Noriaki Nagai; Megumu Toda; Masashi Otani; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. Removal of Arsenic(III) Ion from Aqueous Media Using Complex Nickel-Aluminum and Nickel-Aluminum-Zirconium Hydroxides. Water 2020, 12, 1697 .

AMA Style

Fumihiko Ogata, Noriaki Nagai, Megumu Toda, Masashi Otani, Chalermpong Saenjum, Takehiro Nakamura, Naohito Kawasaki. Removal of Arsenic(III) Ion from Aqueous Media Using Complex Nickel-Aluminum and Nickel-Aluminum-Zirconium Hydroxides. Water. 2020; 12 (6):1697.

Chicago/Turabian Style

Fumihiko Ogata; Noriaki Nagai; Megumu Toda; Masashi Otani; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. 2020. "Removal of Arsenic(III) Ion from Aqueous Media Using Complex Nickel-Aluminum and Nickel-Aluminum-Zirconium Hydroxides." Water 12, no. 6: 1697.

Journal article
Published: 05 June 2020 in Antioxidants
Reads 0
Downloads 0

In this study, we investigated the formation of stable radicals and compounds related to antioxidants in Camellia japonica seeds using high performance liquid chromatography (HPLC) and X-band electron paramagnetic resonance imaging (EPRI). The C. japonica seed coat extracts exhibited antioxidant activity in both in vitro and cell-based studies. The extracts inhibited reactive oxygen and reactive nitrogen species production in cell-based studies. HPLC chromatograms indicated that hydrophilic antioxidant compounds—namely, gallic acid, gallocatechin, epigallocatechin, caffeine, catechin, epicatechin, and epicatechin gallate—were found in the methanolic extract. Lipophilic antioxidant compounds—including α-tocopherol, γ-tocopherol, β-tocopherol, δ-tocopherol, α-tocotrienol, γ-tocotrienol, and δ-tocotrienol—were found in the hexane extract. EPRI primarily detected paramagnetic species in seed coats. These radical species were stable organic radicals based on the peak-to-peak line width and g-values. The signals from these stable radicals were strong and stable with a g-value of 2.002. Noninvasive EPRI of the radicals present in C. japonica seeds indicated that the stable radicals were essentially located in the seed coats. The EPRI of the cotyledon demonstrated that additional radicals were localized at an apex of the cotyledon. The results indicated that the stable radicals detected by EPRI and the hydrophilic and lipophilic antioxidant compounds analyzed by HPLC were related to antioxidant reactants and products.

ACS Style

Chalermpong Saenjum; Thanawat Pattananandecha; Kouichi Nakagawa. Detection of Antioxidant Phytochemicals Isolated from Camellia japonica Seeds Using HPLC and EPR Imaging. Antioxidants 2020, 9, 493 .

AMA Style

Chalermpong Saenjum, Thanawat Pattananandecha, Kouichi Nakagawa. Detection of Antioxidant Phytochemicals Isolated from Camellia japonica Seeds Using HPLC and EPR Imaging. Antioxidants. 2020; 9 (6):493.

Chicago/Turabian Style

Chalermpong Saenjum; Thanawat Pattananandecha; Kouichi Nakagawa. 2020. "Detection of Antioxidant Phytochemicals Isolated from Camellia japonica Seeds Using HPLC and EPR Imaging." Antioxidants 9, no. 6: 493.

Review
Published: 14 April 2020 in Molecules
Reads 0
Downloads 0

The inhibition of viral protease is an important target in antiviral drug discovery and development. To date, protease inhibitor drugs, especially HIV-1 protease inhibitors, have been available for human clinical use in the treatment of coronaviruses. However, these drugs can have adverse side effects and they can become ineffective due to eventual drug resistance. Thus, the search for natural bioactive compounds that were obtained from bio-resources that exert inhibitory capabilities against HIV-1 protease activity is of great interest. Fungi are a source of natural bioactive compounds that offer therapeutic potential in the prevention of viral diseases and for the improvement of human immunomodulation. Here, we made a brief review of the current findings on fungi as producers of protease inhibitors and studies on the relevant candidate fungal bioactive compounds that can offer immunomodulatory activities as potential therapeutic agents of coronaviruses in the future.

ACS Style

Nakarin Suwannarach; Jaturong Kumla; Kanaporn Sujarit; Thanawat Pattananandecha; Chalermpong Saenjum; Saisamorn Lumyong. Natural Bioactive Compounds from Fungi as Potential Candidates for Protease Inhibitors and Immunomodulators to Apply for Coronaviruses. Molecules 2020, 25, 1800 .

AMA Style

Nakarin Suwannarach, Jaturong Kumla, Kanaporn Sujarit, Thanawat Pattananandecha, Chalermpong Saenjum, Saisamorn Lumyong. Natural Bioactive Compounds from Fungi as Potential Candidates for Protease Inhibitors and Immunomodulators to Apply for Coronaviruses. Molecules. 2020; 25 (8):1800.

Chicago/Turabian Style

Nakarin Suwannarach; Jaturong Kumla; Kanaporn Sujarit; Thanawat Pattananandecha; Chalermpong Saenjum; Saisamorn Lumyong. 2020. "Natural Bioactive Compounds from Fungi as Potential Candidates for Protease Inhibitors and Immunomodulators to Apply for Coronaviruses." Molecules 25, no. 8: 1800.

Journal article
Published: 05 April 2020 in Sustainability
Reads 0
Downloads 0

To confirm the capability and mechanisms of Sr(II) and Cs(I) adsorption from the aqueous phase using basil seed (BS), virgin BS, calcined BS (BS500 and BS1000), and enzymatically treated BS, namely Mannanase BGM (M-BS), Pectinase G (P-BS), Hemicellulase (H-BS), and Cellulase A (C-BS) was evaluated. The adsorption capabilities of Sr(II) and Cs(I) of various BS adsorbents were also evaluated. The quantity of Sr(II) and Cs(I) adsorbed onto BS was greater than that of BS500 or BS1000, suggesting that the physicochemical characteristics of the BS surface affected Sr(II) and Cs(I) removal from the aqueous phase. Furthermore, the quantity of Sr(II) and Cs(I) adsorbed onto virgin BS was greater than that of enzymatically treated BS, indicating that glucomannan or (1,4)-xylan in the cellulosic hydrocolloid of the BS strongly affected the adsorption capability of Cs(I) or Sr(II) (except for M-BS in Sr(II) adsorption). Our obtained results indicate that, as an adsorbent, BS was capable of removing Sr(II) and Cs(I) from the aqueous solution.

ACS Style

Yugo Uematsu; Fumihiko Ogata; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. Removing Sr(II) and Cs(I) from the Aqueous Phase Using Basil Seed and Elucidating the Adsorption Mechanism. Sustainability 2020, 12, 2895 .

AMA Style

Yugo Uematsu, Fumihiko Ogata, Chalermpong Saenjum, Takehiro Nakamura, Naohito Kawasaki. Removing Sr(II) and Cs(I) from the Aqueous Phase Using Basil Seed and Elucidating the Adsorption Mechanism. Sustainability. 2020; 12 (7):2895.

Chicago/Turabian Style

Yugo Uematsu; Fumihiko Ogata; Chalermpong Saenjum; Takehiro Nakamura; Naohito Kawasaki. 2020. "Removing Sr(II) and Cs(I) from the Aqueous Phase Using Basil Seed and Elucidating the Adsorption Mechanism." Sustainability 12, no. 7: 2895.

Journal article
Published: 03 April 2020 in BMC Complementary Medicine and Therapies
Reads 0
Downloads 0

Background Cissus quadrangularis Linn. (CQ) has been used in Indian and Thai traditional medicine for healing bone fractures because of numerous active ingredients in CQ. It is still unclear which compounds are the active ingredients for bone formation. Methods The molecular docking technique, the ethanolic extraction along with hexane fractionation, and an in vitro experiment with a human osteoblast cell line (MG-63) were used to narrow down the active compounds, to prepare the CQ extract, and to test biological activities, respectively. Results The molecular docking technique revealed that quercetin and β-sitosterol had highest and lowest potential to bind to estrogen receptors, respectively. Compared to the crude ethanol extract (P1), the ethanolic fraction (P2) was enriched with rutin and quercetin at 65.36 ± 0.75 and 1.06 ± 0.12 mg/g, respectively. Alkaline phosphatase (ALP) activity was significantly enhanced in osteoblasts exposed to the P2 in both tested concentrations. The amount of hydroxyproline was slightly increased in the P1 treatment, while osteocalcin was inhibited. Moreover, the P2 significantly activated osteoprotegerin (OPG) and inhibited receptor activator of nuclear factor κ ligand (RANKL) expression. Conclusions Taken together, the enriched rutin and quercetin fraction of CQ triggered the molecules involved in bone formation and the molecules inhibiting bone resorption.

ACS Style

Jetsada Ruangsuriya; Suporn Charumanee; Supat Jiranusornkul; Panee Sirisa-Ard; Busaban Sirithunyalug; Jakkapan Sirithunyalug; Thanawat Pattananandecha; Chalermpong Saenjum. Depletion of β-sitosterol and enrichment of quercetin and rutin in Cissus quadrangularis Linn fraction enhanced osteogenic but reduced osteoclastogenic marker expression. BMC Complementary Medicine and Therapies 2020, 20, 1 -12.

AMA Style

Jetsada Ruangsuriya, Suporn Charumanee, Supat Jiranusornkul, Panee Sirisa-Ard, Busaban Sirithunyalug, Jakkapan Sirithunyalug, Thanawat Pattananandecha, Chalermpong Saenjum. Depletion of β-sitosterol and enrichment of quercetin and rutin in Cissus quadrangularis Linn fraction enhanced osteogenic but reduced osteoclastogenic marker expression. BMC Complementary Medicine and Therapies. 2020; 20 (1):1-12.

Chicago/Turabian Style

Jetsada Ruangsuriya; Suporn Charumanee; Supat Jiranusornkul; Panee Sirisa-Ard; Busaban Sirithunyalug; Jakkapan Sirithunyalug; Thanawat Pattananandecha; Chalermpong Saenjum. 2020. "Depletion of β-sitosterol and enrichment of quercetin and rutin in Cissus quadrangularis Linn fraction enhanced osteogenic but reduced osteoclastogenic marker expression." BMC Complementary Medicine and Therapies 20, no. 1: 1-12.

Journal article
Published: 14 January 2020 in Cosmetics
Reads 0
Downloads 0

This is the first study to investigate the effect of ethanol concentrations on the phenolic content and biological activities of Sripanya Punica granatum peel extract. Various concentrations of ethanol, (20 to 80% v/v), were used in the maceration process. Extracts were investigated for total phenolic content by the Folin–Ciocalteu method, antioxidant activities by 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay, and anti-tyrosinase activity by a spectrophotometric method. The chemical composition was investigated using high-performance liquid chromatography. The irritation of the extracts was determined by Hen’s egg test–chorioallantoic membrane assay. The results demonstrated that E60, which was extracted using 60% v/v ethanol, had the highest yield (66.23 ± 0.38% w/w), the highest total phenolic content (490.42 ± 7.20 μg GAE/g), and the highest antioxidant and anti-tyrosinase activities. IC50 values on DPPH• and ABTS•+ inhibition were 10.97 ± 0.97 and 6.48 ± 0.06 µg/mL, respectively. The 60% v/v ethanol extract (E60) possessed strong tyrosinase inhibition with an IC50 value of 0.10 ± 0.13 µg/mL, which is more potent than kojic acid. The major constituents were punicalagin (4.05 ± 0.26% w/w) and ellagic acid (0.63 ± 0.04% w/w). E60 was safe for topical application since it did not induce irritation. Therefore, we suggest that E60 is a promising agent for further product development.

ACS Style

Nachtharinee Laosirisathian; Chalermpong Saenjum; Jakkapan Sirithunyalug; Sukum Eitssayeam; Busaban Sirithunyalug; Wantida Chaiyana. The Chemical Composition, Antioxidant and Anti-Tyrosinase Activities, and Irritation Properties of Sripanya Punica granatum Peel Extract. Cosmetics 2020, 7, 7 .

AMA Style

Nachtharinee Laosirisathian, Chalermpong Saenjum, Jakkapan Sirithunyalug, Sukum Eitssayeam, Busaban Sirithunyalug, Wantida Chaiyana. The Chemical Composition, Antioxidant and Anti-Tyrosinase Activities, and Irritation Properties of Sripanya Punica granatum Peel Extract. Cosmetics. 2020; 7 (1):7.

Chicago/Turabian Style

Nachtharinee Laosirisathian; Chalermpong Saenjum; Jakkapan Sirithunyalug; Sukum Eitssayeam; Busaban Sirithunyalug; Wantida Chaiyana. 2020. "The Chemical Composition, Antioxidant and Anti-Tyrosinase Activities, and Irritation Properties of Sripanya Punica granatum Peel Extract." Cosmetics 7, no. 1: 7.

Study protocol
Published: 19 December 2019 in Trials
Reads 0
Downloads 0

Background Current international guidelines recommend the use of a daily topical exit-site antimicrobial to prevent peritoneal dialysis (PD)-related infections. Although nonantibiotic-based therapies are appealing because they may limit antimicrobial resistance, no controlled trials have been conducted to compare topical antimicrobial agents with usual exit-site care for the prevention of PD-related infections among the Thai PD population. We propose a controlled three-arm trial to examine the efficacy and safety of a daily chlorhexidine gluconate-impregnated patch versus mupirocin ointment versus usual exit-site care with normal saline for the prevention of PD-related infections. Methods/Designs This study is a randomized, double-blind, multicenter, active-controlled, clinical trial. Adult patients aged 18 years or older who have end-stage kidney disease and are undergoing PD will be enrolled at three PD Centers in Thailand. A total of 354 PD patients will be randomly assigned to either the 2% chlorhexidine gluconate-impregnated patch, mupirocin ointment, or usual exit-site care with normal saline dressing according to a computer-generated random allocation sequence. Participants will be followed until discontinuation of PD or completion of 24 months. The primary study outcomes are time to first PD-related infection (exit-site/tunnel infection or peritonitis) event and the overall difference in PD-related infection rates between study arms. Secondary study outcomes will include (i) the rate of infection-related catheter removal and PD technique failure, (ii) rate of nasal and exit-site Staphylococcus aureus colonization, (iii) healthcare costs, and (iv) skin reactions and adverse events. We plan to conduct a cost-utility analysis alongside the trial from the perspectives of patients and society. A Markov simulation model will be used to estimate the total cost and health outcome in terms of quality-adjusted life years (QALYs) over a 20-year time horizon. An incremental cost-effectiveness ratio in Thai Baht and U.S. dollars per QALYs gained will be illustrated. A series of probabilistic sensitivity analyses will be conducted to assess the robustness of the cost-utility analysis findings. Discussion The results from this study will provide new clinical and cost-effectiveness evidence to support the best strategy for the prevention of PD-related infections among the Thai PD population. Trial registration ClinicalTrials.gov, NCT02547103. Registered on September 11, 2015.

ACS Style

Surapon Nochaiwong; Chidchanok Ruengorn; Kajohnsak Noppakun; Setthapon Panyathong; Phongsak Dandecha; Manish M. Sood; Chalermpong Saenjum; Ratanaporn Awiphan; Sasithorn Sirilun; Pajaree Mongkhon; Wilaiwan Chongruksut; Kednapa Thavorn; for The Thai Renal Outcomes Research (THOR) investigators. Comparative Effectiveness of Local Application of Chlorhexidine Gluconate, Mupirocin Ointment, and Normal Saline for the Prevention of Peritoneal Dialysis-related Infections (COSMO-PD Trial): a multicenter randomized, double-blind, controlled protocol. Trials 2019, 20, 754 -11.

AMA Style

Surapon Nochaiwong, Chidchanok Ruengorn, Kajohnsak Noppakun, Setthapon Panyathong, Phongsak Dandecha, Manish M. Sood, Chalermpong Saenjum, Ratanaporn Awiphan, Sasithorn Sirilun, Pajaree Mongkhon, Wilaiwan Chongruksut, Kednapa Thavorn, for The Thai Renal Outcomes Research (THOR) investigators. Comparative Effectiveness of Local Application of Chlorhexidine Gluconate, Mupirocin Ointment, and Normal Saline for the Prevention of Peritoneal Dialysis-related Infections (COSMO-PD Trial): a multicenter randomized, double-blind, controlled protocol. Trials. 2019; 20 (1):754-11.

Chicago/Turabian Style

Surapon Nochaiwong; Chidchanok Ruengorn; Kajohnsak Noppakun; Setthapon Panyathong; Phongsak Dandecha; Manish M. Sood; Chalermpong Saenjum; Ratanaporn Awiphan; Sasithorn Sirilun; Pajaree Mongkhon; Wilaiwan Chongruksut; Kednapa Thavorn; for The Thai Renal Outcomes Research (THOR) investigators. 2019. "Comparative Effectiveness of Local Application of Chlorhexidine Gluconate, Mupirocin Ointment, and Normal Saline for the Prevention of Peritoneal Dialysis-related Infections (COSMO-PD Trial): a multicenter randomized, double-blind, controlled protocol." Trials 20, no. 1: 754-11.

Journal article
Published: 10 April 2019 in Fermentation
Reads 0
Downloads 0

A direct bioconversion of gelatinized starchy waste (GSW) to lactic acid by amylolytic lactic acid bacterium Lactobacillus plantarum S21 was investigated. Corn steep liquor (CSL) was selected as the most suitable low-cost nitrogen source for replacing yeast extract, beef extract, and peptone in De Man, Rogosa and Sharpe (MRS) medium. Plackett–Burman design results indicated that GSW and CSL were the two most nutrients that significantly influence lactic acid production, among eight medium components, including GSW, CSL, K2HPO4, CH3COONa, (NH4)2HC6H5O7, MgSO4, MnSO4, and Tween 80. A new low-cost medium containing only GSW (134.4 g/L) and CSL (187.7 g/L) was achieved as omitting other six components from the optimized medium had no effect on lactic acid yield. Batch fermentation at 37 °C both in 1 L and 10 L jar fermenters showed non-significantly different productivity. A by-product, maltose-forming α-amylase, was successfully achieved up to 96% recovery yield using an ultrafiltration unit equipped with a 50 kDa cut-off membrane. Crude lactic acid exhibited the additional benefit of antimicrobial activity against food and feed pathogens Salmonella enterica serovar Typhimurium TISTR 292, Vibrio cholerae TH-001, and also E. coli ATCC 25922. This study presents a promising bioprocess for the simultaneous production of lactic acid, and a value-added food enzyme, using only two industrial wastes, GSW and CSL, as the medium components.

ACS Style

Kridsada Unban; Apinun Kanpiengjai; Nuttapong Khatthongngam; Chalermpong Saenjum; Chartchai Khanongnuch. Simultaneous Bioconversion of Gelatinized Starchy Waste from the Rice Noodle Manufacturing Process to Lactic Acid and Maltose-Forming α-Amylase by Lactobacillus plantarum S21, Using a Low-Cost Medium. Fermentation 2019, 5, 32 .

AMA Style

Kridsada Unban, Apinun Kanpiengjai, Nuttapong Khatthongngam, Chalermpong Saenjum, Chartchai Khanongnuch. Simultaneous Bioconversion of Gelatinized Starchy Waste from the Rice Noodle Manufacturing Process to Lactic Acid and Maltose-Forming α-Amylase by Lactobacillus plantarum S21, Using a Low-Cost Medium. Fermentation. 2019; 5 (2):32.

Chicago/Turabian Style

Kridsada Unban; Apinun Kanpiengjai; Nuttapong Khatthongngam; Chalermpong Saenjum; Chartchai Khanongnuch. 2019. "Simultaneous Bioconversion of Gelatinized Starchy Waste from the Rice Noodle Manufacturing Process to Lactic Acid and Maltose-Forming α-Amylase by Lactobacillus plantarum S21, Using a Low-Cost Medium." Fermentation 5, no. 2: 32.