Natalie Klempel

Natalie Klempel


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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NKNatalie Klempel
Natalie Klempel
Nicole E. BlackburnNicole E. Blackburn
Nicole E. Blackburn
IMIlona L. McMullan
Ilona L. McMullan
Jason J WilsonJason J Wilson
Jason J Wilson
Lee SmithLee Smith
Lee Smith
Mark TullyMark Tully
Mark Tully
Physical activity is an important determinant of health in later life. The public health restrictions in response to COVID-19 have interrupted habitual physical activity behaviours in older adults. In response, numerous exercise programmes have been developed for older adults, many involving chair-based exercise. The aim of this systematic review was to synthesise the effects of chair-based exercise on the health of older adults. Ovid Medline, EMBASE, CINAHL, AMED, PyscInfo and SPORTDiscus databases were searched from inception to 1 April 2020. Chair-based exercise programmes in adults ≥50 years, lasting for at least 2 weeks and measuring the impact on physical function were included. Risk of bias of included studies were assessed using Cochrane risk of bias tool v2. Intervention content was described using TiDieR Criteria. Where sufficient studies (≥3 studies) reported data on an outcome, a random effects meta-analysis was performed. In total, 25 studies were included, with 19 studies in the meta-analyses. Seventeen studies had a low risk of bias and five had a high risk of bias. In this systematic review including 1388 participants, results demonstrated that chair-based exercise programmes improve upper extremity (handgrip strength: MD = 2.10; 95% CI = 0.76, 3.43 and 30 s arm curl test: MD = 2.82; 95% CI = 1.34, 4.31) and lower extremity function (30 s chair stand: MD 2.25; 95% CI = 0.64, 3.86). The findings suggest that chair-based exercises are effective and should be promoted as simple and easily implemented activities to maintain and develop strength for older adults.

3 June 2024 in Physical Therapy in Sport
Verified
Journal Article
Open access
NSNiamh Sheehan
Niamh Sheehan
RSRyan Summersby
Ryan Summersby
CBChris Bleakley
Chris Bleakley
BCBrian Caulfield
Brian Caulfield
MMMark Matthews
Mark Matthews
SHSinead Holden
Sinead Holden
The aim of this review is to synthesise qualitative studies examining adolescents' experience with pain and injury arising from sports participation. This review was registered on Open Science Framework prior to data extraction. A systematic search of PubMed, Embase, and SPORTDiscus was conducted. Studies were appraised using the CASP (critical appraisal skills programme) checklist. Data was synthesised using a meta aggregation. Inclusion criteria included studies related to adolescents aged 14-19yrs with sports related pain/injury, employed a qualitative design, full text publications in English. Sixteen studies of 216 participants were included. Studies investigated severe knee injuries, concussion, or other musculoskeletal injuries. Synthesised findings show that, regardless of injury type, adolescents experience a mix of positive (motivation to rehab and return to sport, optimism) and negative emotions (fear of re-injury, isolation, depressive responses) throughout recovery. Common coping strategies were to ignore symptoms, modify activity levels, or seek support. Sports-related pain and injury has a multifaceted effect on the adolescent athlete. There is a pervasive fear of re-injury and social isolation, but the desire to return to sports is facilitated through motivation and support. Peer motivation effects the willingness of the adolescent to persist with rehabilitation.

Verified
Journal Article
Open access
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Jason J WilsonJason J Wilson
Jason J Wilson
IMIlona McMullan
Ilona McMullan
Nicole E. BlackburnNicole E. Blackburn
Nicole E. Blackburn
NKNatalie Klempel
Natalie Klempel
Javier Jerez RoigJavier Jerez Roig
Javier Jerez Roig
Mark TullyMark Tully
Mark Tully
The distribution of physical activity bouts through the day may provide useful information for assessing the impacts of interventions on aspects such as physical function. This study aimed to investigate the associations between physical activity fragmentation, tested using different minimum physical activity bout lengths, with physical function in older adults. The SITLESS project recruited 1360 community-dwelling participants from four European countries (≥65 years old). Physical activity fragmentation was represented as the active-to-sedentary transition probability (ASTP), the reciprocal of the average physical activity bout duration measured using ActiGraph wGT3X+ accelerometers. Four minimum bout lengths were utilised to calculate the ASTP: ≥10-s, ≥60-s, ≥120-s and ≥300-s. Physical function was assessed using the 2-min walk test (2MWT) and the composite score from the Short Physical Performance Battery (SPPB) test. Linear regression analyses, after adjusting for relevant covariates, were used to assess cross-sectional associations. After adjustment for relevant covariates, lower ASTP using ≥10-s bouts were associated with longer 2MWT distances and higher SPPB scores. Lower ASTP using ≥120-s bouts and ≥300-s bouts were associated with longer 2MWT distances but not the SPPB. Less fragmented physical activity patterns appeared to be associated with better physical function in community-dwelling older adults.

15 October 2024 in BMJ Open
Verified
Journal Article
Open access
PDF file
KPKaty Pedlow
Katy Pedlow
NKNiamh C Kennedy
Niamh C Kennedy
NKNatalie Klempel
Natalie Klempel
JEJanice J. Eng
Janice J. Eng
GAGary Adamson
Gary Adamson
SMSuzanne McDonough
Suzanne McDonough
Background Less than 50% of stroke survivors regain their pre-stroke level of upper limb function, compounded with a lack of long-term rehabilitation options available. The Graded Repetitive Arm Supplementary Programme (GRASP) is an evidence-based upper limb programme delivered as a standalone programme to stroke survivors. To improve access to such a programme, there is the potential to combine it with a high-utility community-based exercise programme, such as the post-rehabilitation enablement programme (PREP). We aimed to establish if this was feasible to deliver alongside the experience of stroke survivors and therapists, identify any refinements the intervention and the acceptability of the intervention and trial procedures. Methods A cluster feasibility-controlled trial was conducted using both quantitative and qualitative outcome measures with stroke survivors who were discharged from NHS care. Participants completed PREP for 6 weeks (control), with the intervention group also completing GRASP. The GRASP intervention was refined in between five iterative testing cycles. Focus groups with participants explored the acceptability and feasibility. Individual interviews with intervention therapists explored how feasible it was to embed the intervention into practice, and determine the feasibility of a future larger, mixed methods, randomised controlled trial. Clinical endpoints for upper limb and overall function were explored through the Rating of Everyday Arm use in the Community and Home, 10-metre walk test (10MWT) and quality of life via the Shortened Edinburgh Warwick questionnaire. No further suggestions for intervention design were noted after cycle 4. Results Recruitment (n=72) and retention levels (84.7%) were high with 61 participants (mean age of 66 years and 49 weeks post-stroke) completing the study. Participants and therapists reported positive acceptability of the intervention with goal setting and family support noted as beneficial. The home exercise programme was noted as challenging. Participants within both groups demonstrated improvements in clinical measures, with the intervention group demonstrating a greater improvement within the Rating of Everyday Arm-use in the Community and Home and the 10MWT. Conclusion This study successfully recruited and retained stroke survivors into an upper limb community-based programme. It poses a feasible delivery mechanism to combine evidence-based upper limb approaches with established physical activity programmes in a future large scale and fully powered study. Trial registration number NCT05090163.

13 October 2023 in Current Physical Medicine and Rehabilitation Reports
Verified
Journal Article
Open access
PDF file
NKNatalie Klempel
Natalie Klempel
NKNiamh Kennedy
Niamh Kennedy
KPKaty Pedlow
Katy Pedlow
Purpose of Review: To determine and examine the evidence of GRASP in an upper limb rehabilitation setting for survivors of stroke. Summary: Five databases were searched: CINAHL Complete, Medline (OVID), Embase, Cochrane Methodological Register, and Open Grey resulting in 8 studies for this review. Studies that included survivors of stroke using GRASP, participants over 18 years, and full-text articles were used. The Down’s and Black checklist and Critical Appraisal Skills Programme were used to assess risk of bias. Recent Findings: A narrative synthesis of results, including setting and exercise time, was conducted to provide a comprehensive overview of the clinical measures. The findings of this review revealed that those who used GRASP showed an increase in hand strength/dexterity, upper limb function, and in the activities of daily living. The setting of GRASP provides implications for the way the program can be delivered in the future.

20 January 2023 in BMJ Open
Verified
Journal Article
Open access
PDF file
KPKaty Pedlow
Katy Pedlow
SMSuzanne McDonough
Suzanne McDonough
NKNatalie Klempel
Natalie Klempel
JHJenny Hylands
Jenny Hylands
NHNoelene Hughes
Noelene Hughes
NKNiamh Kennedy
Niamh Kennedy
Introduction Poor recovery of the upper limb following a stroke has been recognised as a significant problem in the UK. Although there is good evidence that early, intense rehabilitation can lead to upper limb recovery, often this is not maintained, with less than 50% of people regaining the ability to use their upper limb for independent function at 6 months. Upper limb recovery potential is reported for many years poststroke, yet current long-term provision is insufficient. Methods and analysis 60 participants will be recruited into this feasibility study, with 30 allocated to a Post Rehabilitation Enablement Programme (PREP) alone and 30 allocated to a combined programme, PREP Plus, consisting of PREP and the Graded Repetitive Arm Supplementary Programme (GRASP). We will aim to complete four iterative waves. Within each wave, the intervention design will be refined, based on participant feedback. Within each wave, there will be one cluster unit (one intervention group ;PREP Plus) and one control group ;PREP alone)). A total of five PREP sites within Northern Ireland Health and Social Care Trusts will be used for this study. PREP Plus will have a home exercise component along with exercises logs and a behaviour contract. Qualitative and quantitative measures will evaluate the acceptability and feasibility to determine how feasible it is to embed the intervention into practice, as well as to determine the feasibility of a larger, mixed-methods, randomised controlled trial to assess intervention efficacy. Clinical endpoints will also be explored. Ethics and dissemination This study has been approved by the Health and Social Care Research Ethics Committee A, IRAS project ID (278620). Participants will provide informed consent prior to participating in the study. Information outlining the purpose of the study, what data will be collected and how the data will be managed will be provided. Results will be published in peer-reviewed journals and any published data will be available on the university data repository. The project management group will advise on different avenues for dissemination to ensure it reaches appropriate audiences. Trial registration number NCT05090163.