Breast cancer is one of the most common and deadliest cancers among women. Since histopathological images contain sufficient phenotypic information, they play an indispensable role in the diagnosis and treatment of breast cancers. To improve the accuracy and objectivity of Breast Histopathological Image Analysis (BHIA), Artificial Neural Network (ANN) approaches are widely used in the segmentation and classification tasks of breast histopathological images. In this review, we present a comprehensive overview of the BHIA techniques based on ANNs. First of all, we categorize the BHIA systems into classical and deep neural networks for in-depth investigation. Then, the relevant studies based on BHIA systems are presented. After that, we analyze the existing models to discover the most suitable algorithms. Finally, publicly accessible datasets, along with their download links, are provided for the convenience of future researchers.

Ultrasound (US) is one of the most widely used imaging modalities in medical diagnosis. It has the advantages of real-time, low cost, noninvasive nature, and easy to operate. However, it also has the unique disadvantages of strong artifacts and noise and high dependence on the experience of doctors. In order to overcome the shortcomings of ultrasound diagnosis and help doctor improve the accuracy and efficiency of diagnosis, many computer aided diagnosis (CAD) systems have been developed. In recent years, deep learning has achieved great success in computer vision with its unique advantages. In the aspect of medical US image analysis, deep learning has also been exploited for its great potential and more and more researchers apply it to CAD systems. In this paper, we first introduce the deep learning models commonly used in medical US image analysis; Second, we review the data preprocessing methods of medical US images, including data augmentation, denoising, and enhancement; Finally, we analyze the applications of deep learning in medical US imaging tasks (such as image classification, object detection, and image reconstruction).

In recent years, researches are concentrating on the effectiveness of Transfer Learning (TL) and Ensemble Learning (EL) techniques in cervical histopathology image analysis. However, there have been very few investigations that have described the stages of differentiation of cervical histopathological images. Therefore, in this article, we propose an Ensembled Transfer Learning (ETL) framework to classify well, moderate and poorly differentiated cervical histopathological images. First of all, we have developed Inception-V3, Xception, VGG-16, and Resnet-50 based TL structures. Then, to enhance the classification performance, a weighted voting based EL strategy is introduced. After that, to evaluate the proposed algorithm, a dataset consisting of 307 images, stained by three immunohistochemistry methods (AQP, HIF, and VEGF) is considered. In the experiment, we obtain the highest overall accuracy of 97:03% and 98:61% on AQP staining images and poor differentiation of VEGF staining images, individually. Finally, an additional experiment for classifying the benign cells from the malignant ones is carried out on the Herlev dataset and obtains an overall accuracy of 98:37%.

Cervical cancer is one of the most common and deadliest cancers among women. Despite that, this cancer is entirely treatable if it is detected at a precancerous stage. Pap smear test is the most extensively performed screening method for early detection of cervical cancer. However, this hand-operated screening approach suffers from a high false-positive result because of human errors. To improve the accuracy and manual screening practice, computer-aided diagnosis methods based on deep learning is developed widely to segment and classify the cervical cytology images automatically. In this survey, we provide a comprehensive study of the state of the art approaches based on deep learning for the analysis of cervical cytology images. Firstly, we introduce deep learning and its simplified architectures that have been used in this field. Secondly, we discuss the publicly available cervical cytopathology datasets and evaluation metrics for segmentation and classification tasks. Then, a thorough review of the recent development of deep learning for the segmentation and classification of cervical cytology images is presented. Finally, we investigate the existing methodology along with the most suitable techniques for the analysis of pap smear cells.

CT screening has been proven to be effective for diagnosing lung cancer at its early manifestation in the form of pulmonary nodules, thus decreasing the mortality. However, the exponential increase of image data makes their accurate assessment a very challenging task given that the number of radiologists is limited and they have been overworked. Recently, numerous methods, especially ones based on deep learning with convolutional neural network (CNN), have been developed to automatically detect and classify pulmonary nodules in medical images. In this paper, we present a comprehensive analysis of these methods and their performances. First, we briefly introduce the fundamental knowledge of CNN as well as the reasons of their suitability to medical images analysis. Then, a brief description of various medical images datasets as well as the environmental setup essential for facilitating lung nodule investigations with CNNs is presented. Furthermore, comprehensive overviews of recent progresses in pulmonary nodule analysis using CNNs are provided. Finally, existing challenges and promising directions for further improving the application of CNN to medical images analysis and pulmonary nodule assessment in particular are discussed. It is shown that CNNs have greatly transformed the early diagnosis and management of lung cancer. We believe that this review will provide all the medical research communities with necessary knowledge to master the concept of CNN so as to utilize it for improving the overall human healthcare system.