Neurotransmitters as electrochemical signaling molecules are essential for proper brain function and their dysfunction is involved in several mental disorders. Therefore, the accurate detection and monitoring of these substances are crucial in brain studies. Neurotransmitters are present in the nervous system at very low concentrations, and they mixed with many other biochemical molecules and minerals, thus making their selective detection and measurement difficult. Although numerous techniques to do so have been proposed in the literature, neurotransmitter monitoring in the brain is still a challenge and the subject of ongoing research. This article reviews the current advances and trends in neurotransmitters detection techniques, including in vivo sampling and imaging techniques, electrochemical and nano-object sensing techniques for in vitro and in vivo detection, as well as spectrometric, analytical and derivatization-based methods mainly used for in vitro research. The document analyzes the strengths and weaknesses of each method, with the aim to offer selection guidelines for neuro-engineering research.

In this paper, we present a new mobile wireless communication platform for real-time monitoring of an individual’s breathing rate. The platform takes the form of a wearable stretching T-shirt featuring a sensor and a detection base station. The sensor is formed by a spiral-shaped antenna made from a multi-material fiber connected to a compact transmitter. Based on the resonance frequency of the antenna at approximately 2.4 GHz, the breathing sensor relies on its Bluetooth transmitter. The contactless and non-invasive sensor is designed without compromising the user’s comfort. The sensing mechanism of the system is based on the detection of the signal amplitude transmitted wirelessly by the sensor, which is found to be sensitive to strain. We demonstrate the capability of the platform to detect the breathing rates of four male volunteers who are not in movement. The breathing pattern is obtained through the received signal strength indicator (RSSI) which is filtered and analyzed with home-made algorithms in the portable system. Numerical simulations of human breath are performed to support the experimental detection, and both results are in a good agreement. Slow, fast, regular, irregular, and shallow breathing types are successfully recorded within a frequency interval of 0.16–1.2 Hz, leading to a breathing rate varying from 10 to 72 breaths per minute.

The rapid electrochemical identification and quantification of neurotransmitters being a challenge in the ever-growing field of neuroelectronics, we aimed to facilitate the electrochemical selective detection of dopamine by functionalizing commercially available electrodes through the deposition of a thin film containing pre-formed gold nanoparticles. The influence of different parameters and experimental conditions, such as buffer solution, fiber material, concentration, and cyclic voltammetry (CV) cycle number, were tested during neurotransmitter detection. In each case, without drastically changing the outcome of the functionalization process, the selectivity towards dopamine was improved. The detected oxidation current for dopamine was increased by 92%, while ascorbic acid and serotonin oxidation currents were lowered by 66% under the best conditions. Moreover, dopamine sensing was successfully achieved in tandem with home-made triple electrodes and an in-house built potentiostat at a high scan rate mode.

Smart textiles and wearable antennas along with broadband mobile technologies have empowered the wearable sensors for significant impact on the future of digital health care. Despite the recent development in this field, challenges related to lack of accuracy, reliability, user’s comfort, rigid form and challenges in data analysis and interpretation have limited their wide-scale application. Therefore, the necessity of developing a new reliable and user friendly approach to face these problems is more than urgent. In this paper, a new generation of wearable antenna is presented, and its potential use as a contactless and non-invasive sensor for human breath detection is demonstrated. The antenna is made from multimaterial fiber designed for short-range wireless network applications at 2.4 GHz frequency. The used composite metal-glass-polymer fibers permits their integration into a textile without compromising comfort or restricting movement of the user due to their high flexibility, and shield efficiently the antenna from the environmental perturbation. The multimaterial fiber approach provided a good radio-frequency emissive properties, while preserving the mechanical and cosmetic properties of the garments. With a smart textile featuring a spiral shape fiber antenna placed on a human chest, a significant shift of the operating frequency of the antenna was observed during the breathing process. The frequency shift is caused by the deformation of the antenna geometry due to the chest expansion, and to the modification of the dielectric properties of the chest during the breath. We demonstrate experimentally that the standard wireless networks, which measure the received signal strength indicator (RSSI) via standard Bluetooth protocol, can be used to reliably detect human breathing and estimate the breathing rate in real time. The mobile platform takes the form of a wearable stretching T-shirt featuring a sensor and a detection base station. The sensor is formed by a spiral-shaped antenna connected to a compact Bluetooth transmitter. Breathing patterns were recorded in the case of female and male volunteers. Although the chest anatomy of females and males is different compared, the sensor’s flexibility allowed recording successfully a breathing rate of 0.3 Hz for the female and 0.5 Hz for the male, which corresponds to a breathing rate of 21 breaths per minutes (bpm) and 30 bpm, respectively.

This article presents a critical literature review on the security aspects of field-programmable gate array (FPGA) devices. FPGA devices present unique challenges to cybersecurity through their reconfigurable nature. The article also pays special attention to emerging system-on-chip (SoC) FPGA devices that incorporate a hard processing system (HPS) on the same die as the FPGA logic. While this incorporation reduces the need for vulnerable external signals, the HPS in SoC FPGA devices adds a level of complexity that is not present for stand-alone FPGA devices. This added complexity necessarily hands over the task of securing the device to developers. Even with standard security features in place, the HPS might still have unhindered access to the FPGA logic. A single software flaw could open up a breach that might allow an attacker to extract the FPGA’s configuration data. A robust cybersecurity strategy is thus required for developers. As such, this work aims to provide the groundwork to build a solid threat-based cybersecurity design strategy that is specially adapted to SoC FPGA devices.

A flexible sinusoidal-shaped antenna sensor is introduced in this work, which is a modified half-wave dipole that can be used for strain sensing applications. The presented antenna is an improved extension of the previously introduced antenna sensor for respiration monitoring. The electrical and radiative characteristics of the sinusoidal antenna and the effects of the geometrical factors are studied. An approach is provided for designing the antenna, and equations are introduced to estimate the geometrical parameters based on desired electrical specifications. It is shown that the antenna sensor can be designed to have up to 5.5 times more sensitivity compared to the last generation of the antenna sensor previously introduced for respiration monitoring. The conductive polymer material used to fabricate the new antenna makes it more flexible and durable compared to the previous generation of antenna sensors made of glass-based material. Finally, a reference antenna made of copper and an antenna sensor made of the conductive polymer are fabricated, and their electrical characteristics are analyzed in free space and over the body.