In the present work, we construct several artificial neural networks (varying the input data) to calculate the saturated hydraulic conductivity (K${}_{\mathrm{S}}$) using a database with 900 measured samples obtained from the Irrigation District 023, in San Juan del Rio, Queretaro, Mexico. All of them were constructed using two hidden layers, a back-propagation algorithm for the learning process, and a logistic function as a nonlinear transfer function. In order to explore different arrays for neurons into hidden layers, we performed the bootstrap technique for each neural network and selected the one with the least Root Mean Square Error (RMSE) value. We also compared these results with pedotransfer functions and another neural networks from the literature. The results show that our artificial neural networks obtained from 0.0459 to 0.0413 in the RMSE measurement, and 0.9725 to 0.9780 for R${}^2$, which are in good agreement with other works. We also found that reducing the amount of the input data offered us better results.