Morsi M Mahmoud

Prof. Morsi M Mahmoud

orcid

Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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2 October 2014 in Microbial Cell Factories
Verified
Journal Article
Open access
PDF file
NBNabih Baeshen
Nabih Baeshen
MBMohammed N Baeshen
Mohammed N Baeshen
ASABDULLAH SHEIKH
ABDULLAH SHEIKH
RBRoop Singh Bora
Roop Singh Bora
MMMorsi M Mahmoud
Morsi M Mahmoud
ERElrashdy M. Redwan
Elrashdy M. Redwan
The rapid increase in the number of diabetic patients globally and exploration of alternate insulin delivery methods such as inhalation or oral route that rely on higher doses, is bound to escalate the demand for recombinant insulin in near future. Current manufacturing technologies would be unable to meet the growing demand of affordable insulin due to limitation in production capacity and high production cost. Manufacturing of therapeutic recombinant proteins require an appropriate host organism with efficient machinery for posttranslational modifications and protein refolding. Recombinant human insulin has been produced predominantly using E. coli and Saccharomyces cerevisiae for therapeutic use in human. We would focus in this review, on various approaches that can be exploited to increase the production of a biologically active insulin and its analogues in E. coli and yeast. Transgenic plants are also very attractive expression system, which can be exploited to produce insulin in large quantities for therapeutic use in human. Plant-based expression system hold tremendous potential for high-capacity production of insulin in very cost-effective manner. Very high level of expression of biologically active proinsulin in seeds or leaves with long-term stability, offers a low-cost technology for both injectable as well as oral delivery of proinsulin.

1 March 2011 in Carbohydrate Polymers
Verified
Journal Article
Closed access
WEWaleed K. El-Zawawy
Waleed K. El-Zawawy
MIMaha M. Ibrahim
Maha M. Ibrahim
YAYasser R. Abdel-Fattah
Yasser R. Abdel-Fattah
NSNadia A. Soliman
Nadia A. Soliman
MMMorsi M Mahmoud
Morsi M Mahmoud

1 February 2011 in Journal of Non-Crystalline Solids
Verified
Journal Article
Closed access
MEM.F. Elkady
M.F. Elkady
MMMorsi M Mahmoud
Morsi M Mahmoud
HAH.M. Abd-El-Rahman
H.M. Abd-El-Rahman

1 September 2010 in Journal of Alloys and Compounds
Verified
Journal Article
Closed access
AIAmal M. Ibrahim
Amal M. Ibrahim
MEM.M. Abd El-Latif
M.M. Abd El-Latif
MMMorsi M Mahmoud
Morsi M Mahmoud

1 April 2015 in Journal of Alloys and Compounds
Verified
Journal Article
Closed access
MMMorsi M Mahmoud
Morsi M Mahmoud
GLGuido Link
Guido Link
MTManfred Thumm
Manfred Thumm

1 June 2016 in Solid State Ionics
Verified
Journal Article
Closed access
YCYuantao Cui
Yuantao Cui
MMMorsi M Mahmoud
Morsi M Mahmoud
MRMagnus Rohde
Magnus Rohde
Carlos ZiebertCarlos Ziebert
Carlos Ziebert
HSHans Juergen Seifert
Hans Juergen Seifert