The idea that maladaptive stress impairs cognitive function has been a cornerstone of decades in basic and clinical research. However, disparate findings have reinforced the need to aggregate results from multiple sources in order to confirm the validity of such statement. In this work, a systematic review and meta-analyses were performed to aggregate results from rodent studies investigating the impact of chronic stress on learning and memory. Results obtained from the included studies revealed a significant effect of stress on global cognitive performance. In addition, stressed rodents presented worse consolidation of learned memories, although no significantly differences between groups at the acquisition phase were found. Despite the methodological heterogeneity across studies, these effects were independent of the type of stress, animals’ strains or age. However, our findings suggest that stress yields a more detrimental effect on spatial navigation tests’ performance. Surprisingly, the vast majority of the selected studies in this field did not report appropriate statistics and were excluded from the quantitative analysis. We have therefore purposed a set of guidelines termed PROBE (Preferred Reporting Orientations for Behavioral Experiments) to promote an adequate reporting of behavioral experiments.
18 September 2016 in Youth Violence and Juvenile Justice
The Dark Triad is represented by three interrelated personality characteristics thought to share a “dark core”—that is, to be associated with a range of negative outcomes. We investigate this link alongside another potent predictor of crime, low self-control. Our analyses found the Dark Triad was strongly predictive of delinquency, especially violent delinquency, where it accounted for the effects of self-control. Yet it exerted no significant effect on drug-based delinquency. However, an interaction between the Dark Triad and low self-control remained substantive and predictive across all models, where low self-control amplified the effects of the Dark Triad on delinquency.