Purpose: Multiple sclerosis is an autoimmune disease that affects the central nerve system, resulting in cumulative loss of motor function. Multiple sclerosis is induced through multiple mechanisms and is caused by inflammation and demyelination. This study aims to evaluate the neuroprotective effect of swimming exercise in experimental autoimmune encephalomyelitis (EAE) rats, an animal model of multiple sclerosis.Methods: EAE was induced by an intradermal injection of 50-μg purified myelin oligodendrocyte glycoprotein 33–55 (MOG33-55) dissolved in 200-μL saline at the base of the tail. The rats in the swimming exercise group were made to swim for 30 minutes once pert a day for 26 consecutive days, starting 5 days after induction of EAE. To compare the effect of swimming exercise with interferon-β, a drug for multiple sclerosis, interferon-β was injected intraperitoneally into rats of the EAE-induced and interferon-β-treated group during the exercise period.Results: Injection of MOG33-55 caused weight loss, decreased clinical disability score, and increased level of pro-inflammatory cytokines and inflammatory mediators in the lumbar spinal cord. Loss of motor function and weakness increased demyelination score. Swimming exercise suppressed demyelination and expression of pro-inflammatory cytokines and inflammatory mediators. These changes promoted recovery of EAE symptoms such as body weight loss, motor dysfunction, and weakness. Swimming exercise caused the same level of improvement as interferon-β treatment.Conclusions: The results of this experiment suggest the possibility of swimming exercise in urological diseases that are difficult to treat. Swimming exercises can be considered for relief of symptom in incurable multiple sclerosis.
27 April 2023 in Journal of Exercise Rehabilitation
The purpose of this study was to evaluate the characteristics of golf-re-lated musculoskeletal injuries. Golfers were retrospectively surveyed through a 50-item questionnaire. Golfers were divided into injured and noninjured groups according to the presence or absence of musculo-skeletal injuries. Of the 208 respondents, 64.0% suffered golf-related in-juries, most of which were minor injuries caused by overuse in the early 9.9 weeks. According to the anatomical distribution, the most injured parts were upper limbs, spine, trunk, and lower limbs in that order. As for the distribution by part, the hand and wrist were the most vulnera-ble, and the lateral elbow damage was 3 times more common than the inner elbow. Self-management for injuries was the most common treat-ment, and regular preventive exercise accounted for 30% of the injured. Overall, more than half of the respondents suffered from musculoskele-tal injuries, self-management was the most common, and less than one-third did regular exercise to prevent injuries. Therefore, active manage-ment to prevent golf-related musculoskeletal injuries may be necessary.
25 February 2019 in Journal of Exercise Rehabilitation
The focus of this research is to examine the impact of 8 weeks of whole body vibration (WBV) exercise on physical factors by conducting an experiment on 17 male bowling players registered in Korea Bowling Association. Strength of truncus and lower-limb and balance were mea-sured as the physical factors and the impact of WBV exercise on each variable was examined. There was significant increase between groups in flexor-weight ratio of truncus at 60°/sec according to performance after applying WBV exercise. There was significant difference in groups before bowling event in pre and posttest as well as after bowling event in pre and posttest. There was significant difference of extensor-weight ratio in groups after bowling event in pre and posttest. There was significant increase at 60°/sec in flexor-ratio of both left and right lower-limb strength according to performance after applying WBV exercise. There was significant difference between groups before bowling event in pre and posttest as well as after bowling event in pre and posttest. Extensor-weight ratio showed significant difference between groups only before bowling event in pre and posttest. There was significant difference between groups in both left and right balance according to performance after applying WBV exercise. There was significant difference in before bowling event in pre and posttest as well as after bowling event in pre and posttest.
PURPOSE: This study aimed to examine the immunological effects of β-alanine intake for 4 weeks on immune function changes after long-distance exercise and the possibility of β-alanine intake as an effective exercise supplement to improve exercise performance and maintain immune function.METHODS: Eighteen male college students were randomly assigned to two groups, one with two capsules of 250 mg β-alanine and the other with placebo without a nutritional effect. The participants took one capsule each in the morning and evening after the meals. This study was conducted in a double-blinded manner. To analyze the inflammatory cytokines expressed during exercise, a 10 km long-running exercise was performed, and blood was collected from the forearm vein a total of 4 times (at rest, immediately after exercise, 30 minutes, and 60 minutes in recovery).RESULTS: As a result of analyzing the level of inflammatory cytokine IL-6, compared to the placebo group, the β-alanine intake group decreased significantly to 60 minutes after recovery from long-distance aerobic exercise, and both groups showed a significant difference between both periods (p<.001). However, there was no significant difference between the groups based on the measurement period before and after intake. As a result of analyzing the level of TNF-α, the expression of TNF-α in the placebo group was significantly decreased from immediately after long-distance aerobic exercise to 60 minutes after recovery, but in the β-alanine group, TNF-β expression did not occur immediately after exercise, and there was no significant difference until the recovery period; thus, there was no statistically significant difference between the two periods. In addition, there was no significant difference between the groups in terms of the measurement period before and after intake.CONCLUSIONS: Based on the above results, β-alanine intake for 4 weeks is thought to be effective in maintaining temporarily reduced immune function after long-distance exercise by reducing the level of inflammatory cytokines in the study participants.
Smoking is a major global health issue that contributes to various chronic diseases, while hypertension and obesity are considered significant health concerns due to their associated complications, such as cardiovascular diseases and metabolic disorders. In this study, we investigated the associations between current smoking status, hypertension, and obesity among the Korean population, excluding individuals with high blood pressure (systolic blood pressure ≥ 160 mmHg or diastolic blood pressure ≥ 100 mmHg) and those taking antihypertensive medications. Data from the 2015 Korea National Fitness Assessment, encompassing 3457 individuals, were analyzed. Logistic regression analysis was used to examine the effects of current smoking and other variables on hypertension and obesity. The results showed that, among the population that excludes specific hypertension criteria, current smoking status was not significantly associated with hypertension or obesity. However, sex and body mass index were significantly associated with hypertension, and age, sex, and blood pressure were significantly associated with obesity. Future research should utilize larger sample sizes and longitudinal designs to confirm these findings and include a broader range of hypertensive participants to better control for potential confounding variables.
The purpose of this study is to explore the meaning of the middle school sports club and to understand the impact on the self-esteem and social development of middle school students participating in the school sports club. To achieve the purpose of this study, a questionnaire survey was conducted on 450 students by selecting a middle school. Of the 420 collected questionnaires, 399 questionnaires were used as a valid sample. As a result of examining seven areas of self-esteem, self-esteem in five areas excluding domestic ego and personality ego was highest in the group that participated in the league. As a result of examining the difference in social development according to the type of participation in school sports clubs, the league participation group was higher in all five areas. As a result of examining the difference in self-esteem according to the period of participation in school sports clubs, the group participating in the league was high in six areas excluding physical ability, however, it was difficult to see a statistically significant difference. As for the factor related to physical ability, the group with the longest participation period of 13 months or longer was the highest, and there is a statistically significant difference. As a result of examining the difference in social development according to the period of participation in school sports clubs, the group under 6 months was the highest in four areas other than physical activity. Physical activity was highest in the group over 13 months.