This page has only limited features, please log in for full access.

Prof. Dr. Byung Guk Kim
Department of Otolaryngology-Head and Neck Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea

Basic Info


Research Keywords & Expertise

0 Rhinitis
0 Sinusitis
0 rhinology
0 olfactory
0 otorhinolaryngologist

Honors and Awards

The user has no records in this section


Career Timeline

The user has no records in this section.


Short Biography

The user biography is not available.
Following
Followers
Co Authors
The list of users this user is following is empty.
Following: 0 users

Feed

Journal article
Published: 06 April 2021 in Journal of Clinical Medicine
Reads 0
Downloads 0

Objectives: To identify the relationship between pulmonary function and subjective olfactory dysfunction in middle-aged and older adults. Materials and Methods: We used Korea National Health and Nutrition Examination Survey data from 2010 to 2012 to analyze 6191 participants in their 50s or older. Results: The frequency of olfactory dysfunction was 6.8% among the subjects with normal pulmonary function tests, but was significantly more frequent in those diagnosed with restrictive (9.6%) or obstructive (10.1%) pulmonary function. Forced volume vital capacity, forced expiratory volume (FEV)1, FEV6, and peak expiratory flow were significantly lower in the olfactory dysfunction group. The risk of olfactory dysfunction was significantly associated with obstructive pulmonary function (odds ratio (OR) [95% confidence interval (CI)]: 1.449 [1.010–2.081]) after adjusting for confounders (sex, rhinitis, chronic rhinosinusitis, hypertension, dyslipidemia, education level, stress, depressed mood, and suicidal ideation). Conclusion: Middle-aged and older adults with obstructive pulmonary function had a higher incidence of subjective olfactory dysfunction than the normal pulmonary function group. Early olfactory testing may improve the quality of life of patients with obstructive pulmonary function.

ACS Style

Ji-Sun Kim; Jun-Ook Park; Dong-Hyun Lee; Ki-Hong Chang; Byung Kim. Association of Olfactory and Pulmonary Function in Middle-Aged and Older Adults: The Korea National Health and Nutrition Examination Survey. Journal of Clinical Medicine 2021, 10, 1535 .

AMA Style

Ji-Sun Kim, Jun-Ook Park, Dong-Hyun Lee, Ki-Hong Chang, Byung Kim. Association of Olfactory and Pulmonary Function in Middle-Aged and Older Adults: The Korea National Health and Nutrition Examination Survey. Journal of Clinical Medicine. 2021; 10 (7):1535.

Chicago/Turabian Style

Ji-Sun Kim; Jun-Ook Park; Dong-Hyun Lee; Ki-Hong Chang; Byung Kim. 2021. "Association of Olfactory and Pulmonary Function in Middle-Aged and Older Adults: The Korea National Health and Nutrition Examination Survey." Journal of Clinical Medicine 10, no. 7: 1535.

Journal article
Published: 18 February 2021 in Toxics
Reads 0
Downloads 0

Background: Eupatilin is an active flavon extracted from the Artemisia species and has properties such as antioxidant, anti-inflammatory, and anti-cancer. We examined the effect of eupatilin using fine particulate matter (FPM) and human bronchial epithelial cell line (BEAS-2B) to confirm the potential of eupatilin as a therapeutic agent for respiratory diseases caused by FPM. Methods: Reactive oxygen species (ROS) levels were checked by flow cytometry to identify if FPM and eupatilin affect ROS production. Western blotting was performed to identify the mechanism of action of eupatilin in FPM-exposed BEAS-2B cells. Results: When cells were exposed to FPM above 12.5 μg/mL concentration for 24 h, ROS production increased significantly compared to the control. When eupatilin was added to cells exposed to FPM, the ROS level decreased proportionally with the eupatilin dose. The phosphorylation of Akt, NF-κB p65, and p38 MAPK induced by FPM was significantly reduced by eupatilin, respectively. Conclusion: FPM cause respiratory disease by producing ROS in bronchial epithelial cells. Eupatilin has been shown to inhibit ROS production through altering signaling pathways. The ROS inhibiting property of eupatilin can be exploited in FPM induced respiratory disorders.

ACS Style

Dong Lee; Jeong-Min Oh; Hyunsu Choi; Sung Kim; Soo Kim; Byung Kim; Jin Cho; Joohyung Lee; Ji-Sun Kim. Eupatilin Inhibits Reactive Oxygen Species Generation via Akt/NF-κB/MAPK Signaling Pathways in Particulate Matter-Exposed Human Bronchial Epithelial Cells. Toxics 2021, 9, 38 .

AMA Style

Dong Lee, Jeong-Min Oh, Hyunsu Choi, Sung Kim, Soo Kim, Byung Kim, Jin Cho, Joohyung Lee, Ji-Sun Kim. Eupatilin Inhibits Reactive Oxygen Species Generation via Akt/NF-κB/MAPK Signaling Pathways in Particulate Matter-Exposed Human Bronchial Epithelial Cells. Toxics. 2021; 9 (2):38.

Chicago/Turabian Style

Dong Lee; Jeong-Min Oh; Hyunsu Choi; Sung Kim; Soo Kim; Byung Kim; Jin Cho; Joohyung Lee; Ji-Sun Kim. 2021. "Eupatilin Inhibits Reactive Oxygen Species Generation via Akt/NF-κB/MAPK Signaling Pathways in Particulate Matter-Exposed Human Bronchial Epithelial Cells." Toxics 9, no. 2: 38.

Review
Published: 01 August 2020 in Clinical and Experimental Otorhinolaryngology
Reads 0
Downloads 0

Objectives. Although osteotomy is an important part of rhinoplasty, it is known to be closely related to postoperative eyelid edema and ecchymosis. We aimed to evaluate the effects of periosteal elevation prior to osteotomy on eyelid edema and ecchymosis.Methods. Two authors reviewed studies in the Medline, Scopus, and Cochrane databases published through May 2019. Randomized controlled trials comparing periosteal elevation (subperiosteal tunneling) with periosteal preservation that reported eyelid edema or ecchymosis or subconjunctival hemorrhage as outcomes of interest were included. From each study, the baseline characteristics of the study subjects, the quality of the study, the number of patients in the treatment and control groups, and outcomes were extracted.Results. Data for meta-analysis were identified in six studies with a total of 208 patients. Eyelid ecchymosis and edema within 3 days postoperatively were significantly more common in the periosteal elevation group than in the preservation group, although such an association was not found for edema on postoperative day 7 (standardized mean difference [SMD], 0.21; 95% confidence interval [CI], –0.09 to 0.50; I2 =0%). There was no significant difference in subconjunctival hemorrhage on day 1 (SMD, 0.31; 95% CI, –0.09 to 0.72; I2 =0%).Conclusion. Periosteal preservation during lateral osteotomy may reduce eyelid edema and ecchymosis compared to periosteal elevation. Further studies with rigorous research methods should be carried out to determine the effectiveness of different techniques in lateral osteotomy.

ACS Style

Ji-Sun Kim; Sun Hong Kim; Hyesook Lee; Byung Guk Kim; Se Hwan Hwang. Effects of Periosteal Elevation Before Lateral Osteotomy in Rhinoplasty: A Meta-Analysis of Randomized Controlled Trials. Clinical and Experimental Otorhinolaryngology 2020, 13, 268 -273.

AMA Style

Ji-Sun Kim, Sun Hong Kim, Hyesook Lee, Byung Guk Kim, Se Hwan Hwang. Effects of Periosteal Elevation Before Lateral Osteotomy in Rhinoplasty: A Meta-Analysis of Randomized Controlled Trials. Clinical and Experimental Otorhinolaryngology. 2020; 13 (3):268-273.

Chicago/Turabian Style

Ji-Sun Kim; Sun Hong Kim; Hyesook Lee; Byung Guk Kim; Se Hwan Hwang. 2020. "Effects of Periosteal Elevation Before Lateral Osteotomy in Rhinoplasty: A Meta-Analysis of Randomized Controlled Trials." Clinical and Experimental Otorhinolaryngology 13, no. 3: 268-273.

Journal article
Published: 30 March 2020 in BMC Complementary Medicine and Therapies
Reads 0
Downloads 0

Background Particulate matter (PM) can cause various negative acute and chronic diseases of the respiratory system, including the upper airways. Curcumin has been reported to have anti-inflammatory and anti-oxidative effects; therefore, we investigated the effects of curcumin on nasal fibroblasts exposed to urban PM (UPM). Methods Samples of inferior turbinate tissue were obtained from six patients. Flow cytometry was used to assess the levels of reactive oxygen species (ROS) following the treatment of nasal fibroblasts with UPM and/or curcumin. We evaluated the effects of UPM and/or curcumin on the expression of phosphorylated ERK, Nrf2, HO-1, and SOD2 in fibroblasts by Western blotting. Results When UPM was applied to nasal fibroblasts, ROS production was significantly increased in a dose-dependent manner. UPM-exposed fibroblasts caused the activation of ERK to increase HO-1 expression and decrease SOD2 expression. Treatment with curcumin reduced the UPM-mediated increase in ROS; this decrease in ROS occurred in a dose-dependent manner. The UPM-induced activation of ERK was inhibited by curcumin. Nrf2 production was also promoted to increase the expression of HO-1 and SOD2 by curcumin. Conclusion Curcumin reduced ROS production caused by UPM in human nasal fibroblasts in a dose-dependent manner, suggesting that curcumin has anti-oxidative effects and may be useful in the treatment of nasal diseases caused by UPM, such as allergic and chronic rhinitis.

ACS Style

Ji-Sun Kim; Jeong-Min Oh; Hyunsu Choi; Sung Won Kim; Soo Whan Kim; Byung Guk Kim; Jin Hee Cho; Joohyung Lee; Dong Chang Lee. Activation of the Nrf2/HO-1 pathway by curcumin inhibits oxidative stress in human nasal fibroblasts exposed to urban particulate matter. BMC Complementary Medicine and Therapies 2020, 20, 101 -8.

AMA Style

Ji-Sun Kim, Jeong-Min Oh, Hyunsu Choi, Sung Won Kim, Soo Whan Kim, Byung Guk Kim, Jin Hee Cho, Joohyung Lee, Dong Chang Lee. Activation of the Nrf2/HO-1 pathway by curcumin inhibits oxidative stress in human nasal fibroblasts exposed to urban particulate matter. BMC Complementary Medicine and Therapies. 2020; 20 (1):101-8.

Chicago/Turabian Style

Ji-Sun Kim; Jeong-Min Oh; Hyunsu Choi; Sung Won Kim; Soo Whan Kim; Byung Guk Kim; Jin Hee Cho; Joohyung Lee; Dong Chang Lee. 2020. "Activation of the Nrf2/HO-1 pathway by curcumin inhibits oxidative stress in human nasal fibroblasts exposed to urban particulate matter." BMC Complementary Medicine and Therapies 20, no. 1: 101-8.

Review
Published: 25 January 2020 in Brazilian Journal of Otorhinolaryngology
Reads 0
Downloads 0

Several surgical techniques have been used during tonsillectomy to reduce complications. To assess the effects of pillar suture in conjunction with tonsillectomy as compared to tonsillectomy without suture in children. Two authors independently searched five databases (PubMed, SCOPUS, Embase, the Web of Science, and the Cochrane database) for studies published as recent as December 2018. Of the included studies, we compared tonsillectomy and pillar suture in combination (suture groups) with tonsillectomy alone,without suture, (control group). Postoperative pain intensity and other morbidities (e.g., postoperative bleeding, palatal hematoma, discomfort, and pillar edema) were measured during the postoperative period. Postoperative bleeding [primary (OR = 0.47 [0.27; 0.81]) and secondary (OR = 0.14 [0.02; 0.78]) were significantly decreased in the pillar suture group compared to the control group. There were no significant differences between the two groups in postoperative pain at day 7 (SMD = -0.39 [-0.79; 0.00]), palatal hematoma (OR = 5.00 [0.22; 112.88]), palatal discomfort sensation (OR = 2.62 [0.60; 11.46]), site infection (OR = 5.27 [0.24; 113.35]), and velopharyngeal insufficiency (OR = 2.82 [0.11; 74.51]). By contrast, pillar edema (OR = 9.55 [4.29; 21.29]) was significantly increased in the pillar suture group compared to the control group. Pillar suture combined with tonsillectomy may reduce postoperative bleeding incidence despite increasing pillar edema in pediatric tonsillectomy. Postoperative pain-relief, palatal hematoma, palatal discomfort sensation, site infection, and velopharyngeal insufficiency were not significantly altered compared to tonsillectomy alone. However, further studies are needed to corroborate the results of this study.

ACS Style

Ji-Sun Kim; Byung Guk Kim; Dong-Hyun Kim; Se Hwan Hwang. Efficacy of pillar suture for post-tonsillectomy morbidity in children: a meta-analysis. Brazilian Journal of Otorhinolaryngology 2020, 1 .

AMA Style

Ji-Sun Kim, Byung Guk Kim, Dong-Hyun Kim, Se Hwan Hwang. Efficacy of pillar suture for post-tonsillectomy morbidity in children: a meta-analysis. Brazilian Journal of Otorhinolaryngology. 2020; ():1.

Chicago/Turabian Style

Ji-Sun Kim; Byung Guk Kim; Dong-Hyun Kim; Se Hwan Hwang. 2020. "Efficacy of pillar suture for post-tonsillectomy morbidity in children: a meta-analysis." Brazilian Journal of Otorhinolaryngology , no. : 1.

Journal article
Published: 01 January 2009 in Journal of the Korean Society of Radiology
Reads 0
Downloads 0
ACS Style

Song Mee Cho; Byung Guk Kim. A Case of a Retained Surgical Sponge after Endoscopic Sinus Surgery Depicted on CT Imaging. Journal of the Korean Society of Radiology 2009, 61, 91 -93.

AMA Style

Song Mee Cho, Byung Guk Kim. A Case of a Retained Surgical Sponge after Endoscopic Sinus Surgery Depicted on CT Imaging. Journal of the Korean Society of Radiology. 2009; 61 (2):91-93.

Chicago/Turabian Style

Song Mee Cho; Byung Guk Kim. 2009. "A Case of a Retained Surgical Sponge after Endoscopic Sinus Surgery Depicted on CT Imaging." Journal of the Korean Society of Radiology 61, no. 2: 91-93.