Aditya P. Sharma

Dr. Aditya P. Sharma


Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2014 in Surgery for Obesity and Related Diseases
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Journal Article
Closed access
ASAditya P. Sharma
Aditya P. Sharma
SASandeep Aggarwal
Sandeep Aggarwal
VAVineet Ahuja
Vineet Ahuja
CBChandrashekhar Bal
Chandrashekhar Bal

1 November 2020 in Seminars in Cancer Biology
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Journal Article
Closed access
MIMohd Ishaq
Mohd Ishaq
RORani Ojha
Rani Ojha
ASAditya P. Sharma
Aditya P. Sharma
SSShrawan K. Singh
Shrawan K. Singh

1 November 2013 in Journal of Laparoendoscopic & Advanced Surgical Techniques
Verified
Journal Article
Closed access
SASandeep Aggarwal
Sandeep Aggarwal
ASAditya P. Sharma
Aditya P. Sharma
NRNeelakandan Ramaswamy
Neelakandan Ramaswamy
Introduction: Laparoscopic sleeve gastrectomy (LSG) is a popular bariatric procedure with a low complication rate. Serious complications after LSG include gastric leak and staple line bleeding. In order to reduce these complications, staple line reinforcement has been practiced variably by many surgeons. There is no conclusive evidence to suggest that routine oversewing of the staple line or reinforcement with buttressing material after LSG decreases these complications. We therefore undertook a prospective randomized controlled trial to evaluate the impact of oversewing of the staple line in preventing complications after LSG. Patients and Methods: Sixty patients undergoing LSG were randomly allocated to two groups. In Group A, the entire staple line was reinforced with continuous suturing, and in Group B, no reinforcement was used. Thirty patients were enrolled in each group. Indications for this procedure were morbidly obese (body mass index ≥40 kg/m2) or severely obese (body mass index ≥35 kg/m2) patients with comorbidities including type 2 diabetes mellitus, hypertension, sleep apnea, and osteoarthritis. Complications including gastric leak, bleeding, and stricture were recorded. Results: The demographic parameters were comparable in the two groups. Two cases of early gastric leak occurred in Group B and none in Group A. There was no case of staple line bleeding or stricture in either group, although 1 patient in Group B had bleeding from the omentum that required re-operation. The overall surgical complication rate was 5%. The mean operative time in Group A (139±10 minutes) was significantly greater than in Group B (117±19 minutes) (P=.02). Conclusions: Oversewing of the staple line may lead to reduction in leak rate, although a larger study is required to reach a definitive conclusion. The incidence of staple line bleeding can be minimized by following meticulous technique and adequate compression time after closure of the stapler rather than placing undue emphasis on oversewing and expensive buttressing materials.

1 October 2020 in Urology
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Journal Article
Closed access
ACAbhishek Chandna
Abhishek Chandna
RMRavimohan Suryanarayan Mavuduru
Ravimohan Suryanarayan Mavuduru
GBGirdhar Singh Bora
Girdhar Singh Bora
ASAditya P. Sharma
Aditya P. Sharma
KPKalpesh Mahesh Parmar
Kalpesh Mahesh Parmar
SSShrawan Kumar Singh
Shrawan Kumar Singh

1 April 2021 in Journal of Endourology
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Journal Article
Closed access
ATAbhishek Thakur
Abhishek Thakur
ASAditya P. Sharma
Aditya P. Sharma
SDSudheer Kumar Devana
Sudheer Kumar Devana
KPKalpesh Mahesh Parmar
Kalpesh Mahesh Parmar
RMRavimohan S. Mavuduru
Ravimohan S. Mavuduru
AMArup Kumar Mandal
Arup Kumar Mandal
Introduction: Miniaturization of percutaneous nephrolithotomy (mPCNL) was proposed to decrease postoperative bleeding, as there is decreased parenchymal injury compared with standard percutaneous nephrolithotomy (SPCNL). Published randomized controlled trials (RCTs) evaluating bleeding after mPCNL have shown conflicting results. Hence, the evidence to say that mPCNL offers less postoperative bleeding is not robust. Materials and Methods: Prospective RCT was done by comparing mPCNL and SPCNL for treatment of renal stones of size 1 to 3 cm. Patients with active urinary tract infection, renal malformation, uncorrected coagulopathy, and raised serum creatinine (>1.5 mg/dL) were excluded. Blood loss was evaluated by measuring fall in hemoglobin and hematocrit on postoperative day 1. Postoperative pain was evaluated by visual analogue scale (VAS) score at 6, 24, and 48 hours. Results: A total of 60 patients (30 in each arm) were enrolled during the study period. All the baseline preoperative variables were comparable in both the groups. The SPCNL group had a significantly higher drop in hematocrit level as compared with mPCNL (4.6 ± 3.1% vs 3.1 ± 2.1%, p = 0.02). The mean fall in hemoglobin was higher in SPCNL as compared with mPCNL (1.61 ± 0.9 gm% vs 1.21 ± 0.7 gm%, p = 0.07), but it was not significant. Blood transfusion (BT) rate was comparable in both the groups (one patient in each group). The mPCNL group had significantly less VAS scores at 6 hours (3.27 ± 1.20 vs 4.40 ± 1.52, p = 0.002) and 24 hours (2.10 ± 0.54 vs 2.83 ± 1.05, p = 0.001) after surgery. Postoperative complications and hospital stay were comparable in both the arms. Conclusion: mPCNL is associated with less postoperative bleeding and pain than SPCNL. However, the small tract size does not prevent against the clinically significant bleeding requiring BT.

1 January 2018 in Indian Journal of Urology
Verified
Journal Article
Open access
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RMRavimohan Suryanarayana Mavuduru
Ravimohan Suryanarayana Mavuduru
ASAditya P. Sharma
Aditya P. Sharma
GBGirdhar Singh Bora
Girdhar Singh Bora
SDSudheer K Devana
Sudheer K Devana
KPKiruthika Palani
Kiruthika Palani
AMArup K Mandal
Arup K Mandal
Introduction and Objective: The RENAL, PADUA and centrality index (C-index) nephrometry scoring systems (SS) have been individually evaluated for their role in predicting trifecta outcomes after nephron-sparing surgery (NSS). However, there is little data on their comparative superiority. The present study was designed to evaluate the predictive value of three SS and to assess interobserver reliability. Materials and Methods: Fifty patients undergoing NSS at our center between January 2014 and April 2016 were included in the study. The demographic details were noted. Images (computed tomography [CT] scans or magnetic resonance imaging) were reviewed by a urologist and a radiologist independently and RENAL, PADUA, and C-index were calculated. The correlation between these scoring system and trifecta outcomes were calculated. Results: The RENAL and PADUA score did not correlate with any of the perioperative parameters. However, C-index had a significant correlation with operative time (OT) (P = 0.02) and trifecta outcomes (P < 0.05). There was an excellent concordance between the two observers in scoring the RENAL score (α = 0.915; intraclass correlation coefficient [ICC] = 0.814) and PADUA score (α = 0.816; ICC = 0.689 [P < 0.001]). There was lesser although acceptable concordance in the calculation of C-index (ICC −0.552; α −0.711). Conclusions: There is good correlation among all the 3 SS. C-index has lower reproducibility due to difficult mathematical calculation but correlated best with trifecta outcomes.