Zeynep Keskin

Dr. Zeynep Keskin

orcid

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
26 November 2014 in BMC Urology
Verified
Journal Article
Open access
PDF file
SKSuat Keskin
Suat Keskin
ZKZeynep Keskin
Zeynep Keskin
HTHakan Hakki Taskapu
Hakan Hakki Taskapu
HKHavva Kalkan
Havva Kalkan
MKMehmet Kaynar
Mehmet Kaynar
HTHatice Toy
Hatice Toy
To determine the relationship between renal cell carcinoma subtypes and the associated mortality and biochemical parameters. An additional aim was to analyze multiphasic multidetector computed tomography findings. This study is a hospital-based retrospective investigation, using 211 patients with a diagnosis of renal cell carcinoma upon computed tomography examination. The histological subtypes included clear cell in 119 patients, chromophobe cell in 30 patients, papillary cell in 25 patients, mixed cell in 32 patients, and sarcomatoid cell in 4 patients. The mean age of the patients participating in this study was 61.18 ± 11.81 years, and the mortality rate was 10.4% (n = 22) through the 2-year follow-up. The ratios of both the neutrophil-to-lymphocyte upon admission to the hospital and platelet-to-lymphocyte of the non-surviving group were significantly higher than those of the surviving group (p < 0.05). When the analysis of the 2-year survival of the patients was examined according to the median platelet-to-lymphocyte ratio values, the Kaplan-Meier survival curves were significantly different between the surviving and non-surviving groups (p = 0.01). In two-way analysis of variance test, statistically significant results which were influenced by mortality (p = 0.028) and were found between renal cell carcinoma subtypes in the computed tomography density of corticomedullary phase (p = 0.001). The neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio may represent widely available biomarkers in renal cell carcinoma, and the logistic regression model indicated that neutrophil-to-lymphocyte ratio was a significant predictor for mortality. According to the median platelet-to-lymphocyte ratio values, the Kaplan-Meier survival curves were significantly different between the surviving and non-surviving groups.

27 December 2022 in Joint Diseases and Related Surgery
Verified
Journal Article
Open access
PDF file
MGMuhammet Zeki Gültekin
Muhammet Zeki Gültekin
YDYaşar Mahsut DİNÇEL
Yaşar Mahsut DİNÇEL
ZKZeynep Keskin
Zeynep Keskin
SASerdar Arslan
Serdar Arslan
AYAhmet YILDIRIM
Ahmet YILDIRIM
Joint Diseases and Related Surgery (JDRS), the official journal of the Turkish Joint Diseases Foundation, is an international, peer-reviewed, immediate open access journal. All published articles in JDRS has been free for everyone, without embargo, since 1990.

9 June 2013 in Case Reports in Vascular Medicine
Verified
Journal Article
Open access
PDF file
SKSuat Keskin
Suat Keskin
ZKZeynep Keskin
Zeynep Keskin
NSNevin Sekmenli
Nevin Sekmenli
The veins of the azygos system vary greatly in mode of origin, course, numbers of tributaries and anastomoses, and nature of termination. The azygos vein system can take different courses. Such variation is important in mediastinal surgery, and knowledge of congenital variations can be of clinical importance. It is imperative for reporting radiologists to identify such anomalies.

7 August 2022 in Acta Radiologica
Verified
Journal Article
Closed access
ZKZeynep Keskin
Zeynep Keskin
SKSuat Keskin
Suat Keskin
Background: Detection and characterization of renal lesions are common in daily clinical practice. Purpose: To investigate the effectiveness of shear wave elastography (SWE), a novel radiological examination technique, in the characterization of renal masses. Material and Methods: The study included a total of 68 patients (33 men, 35 women; mean age = 57.71 ± 12.08 years; age range = 19–83 years) who underwent SWE. SWE measurements were obtained at depths of 2–8 cm from the probe surface in two different positions from an analysis window of approximately 0.5 × 1.0 cm on ultrasound. The cutoff SWE was calculated for the differentiation of renal cell carcinoma (RCC) and angiomyolipoma (AML) by receiver operating characteristic (ROC) analysis. When the result was statistically significant, the sensitivity, specificity, accuracy, and positive and negative predictive values of the test were calculated. Results: Mass-to-parenchyma SWE ratios of RCCs were significantly higher than those of AMLs ( P = 0.003). In ROC curve analysis, the SWE cutoff was 1.215 m/s to differentiate RCCs from AMLs. The area under the ROC curve was calculated as 0.74 (95% CI = 0.610–0.871, sensitivity = 70.7%, specificity = 70.6%, positive predictive value = 87.8%, negative predictive value = 44.4%). Conclusion: The SWE technique is increasingly used and may be useful in distinguishing RCC and AML lesions, and especially clear cell and non-clear cell RCCs.

24 April 2025 in Tomography
Verified
Journal Article
Open access
PDF file
ZKZeynep Keskin
Zeynep Keskin
MYMihrican Yeşildağ
Mihrican Yeşildağ
OOOmer Ozberk
Omer Ozberk
KÖKemal Ödev
Kemal Ödev
FAFatih Ateş
Fatih Ateş
ŞKŞehriban Çağlak kardaş
Şehriban Çağlak kardaş
Background: This study aims to systematically evaluate the findings from computed tomography (CT) examinations conducted at least three months post-diagnosis of COVID-19 in patients diagnosed between 2020 and 2024. Objective: To determine the frequency and characteristics of CT findings in the post-COVID-19 period, analyze long-term effects on lung parenchyma, and contribute to the development of clinical follow-up and treatment strategies based on the collected data. Materials and Methods: Ethical approval was obtained for this retrospective study, and individual consent was waived. A total of 76 patients were included in the study, aged 18 and older, diagnosed with COVID-19 between March 2020 and November 2024, who underwent follow-up chest CT scans at 3–6 months, 6–12 months, and/or 12 months post-diagnosis. CT images were obtained in the supine position without contrast and evaluated by two experienced radiologists using a CT severity score (CT-SS) system, which quantifies lung involvement. Statistical analyses were performed using IBM SPSS 23.0, with significance set at p < 0.05. Results: The results indicated a mean CT-SS of 10.58 ± 0.659. Significant associations were found between age, CT scores, and the necessity for intensive care or mechanical ventilation. The most common CT findings included ground-glass opacities, reticular patterns, and traction bronchiectasis, particularly increasing with age and over time. Conclusion: This study emphasizes the persistent alterations in lung parenchyma following COVID-19, highlighting the importance of continuous monitoring and tailored treatment strategies for affected patients to improve long-term outcomes.

19 February 2022 in Chinese Journal of Academic Radiology
Verified
Journal Article
Open access
PDF file
ZKZeynep Keskin
Zeynep Keskin
MYMihrican Yeşildağ
Mihrican Yeşildağ
Background Although rarely seen, organizing pneumonia (OP) is a quite characteristic clinicopathological picture among lung diseases. Purpose Here, we aimed to investigate the relationship between neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte ratios (PLR), among the parameters of complete blood count, and the patterns and severity of involvements of cryptogenic organizing pneumonia (COP) in thorax computed tomography (CT). Materials and methods A total of 38 patients diagnosed as COP in our hospital between April 2011–February 2020 were included in the study. The patients’ data were obtained and evaluated retrospectively from the hospital automation system. On CT images, the lobes involved, lesions, locations, focal or multifocal involvements, and patterns of the lungs were evaluated. Whether there was a correlation between CT scores, and NLR and PLR findings was also evaluated. Results NLR was found significantly higher in those with Grade-2 severity scale than that in those with Grade-1 involvement in the Kruskal–Wallis test (p = 0.004). NLR and C-reactive protein (CRP) values were significantly higher among patients with grade-3 involvement of severity scale than those having grade-1 involvement (p = 0.005, p = 0.007). Conclusions In our study, NLR was evaluated as an appropriate parameter in correlation with the severity and prevalence of CT involvement in determining the disease severity in COP patients, and no significant association was found between the disease severity and PLR. Further studies including larger populations and more clinical evaluation parameters are needed to elucidate the entity.