Mareike Buhl

Dr. Mareike Buhl

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 September 2022 in Frontiers in Neurology
Verified
Journal Article
Open access
SSSamira Saak
Samira Saak
DHDavid Huelsmeier
David Huelsmeier
BKBirger Kollmeier
Birger Kollmeier
MBMareike Buhl
Mareike Buhl
For characterizing the complexity of hearing deficits, it is important to consider different aspects of auditory functioning in addition to the audiogram. For this purpose, extensive test batteries have been developed aiming to cover all relevant aspects as defined by experts or model assumptions. However, as the assessment time of physicians is limited, such test batteries are often not used in clinical practice. Instead, fewer measures are used, which vary across clinics. This study aimed at proposing a flexible data-driven approach for characterizing distinct patient groups (patient stratification into auditory profiles) based on one prototypical database (N = 595) containing audiogram data, loudness scaling, speech tests, and anamnesis questions. To further maintain the applicability of the auditory profiles in clinical routine, we built random forest classification models based on a reduced set of audiological measures which are often available in clinics. Different parameterizations regarding binarization strategy, cross-validation procedure, and evaluation metric were compared to determine the optimum classification model. Our data-driven approach, involving model-based clustering, resulted in a set of 13 patient groups, which serve as auditory profiles. The 13 auditory profiles separate patients within certain ranges across audiological measures and are audiologically plausible. Both a normal hearing profile and profiles with varying extents of hearing impairments are defined. Further, a random forest classification model with a combination of a one-vs.-all and one-vs.-one binarization strategy, 10-fold cross-validation, and the kappa evaluation metric was determined as the optimal model. With the selected model, patients can be classified into 12 of the 13 auditory profiles with adequate precision (mean across profiles = 0.9) and sensitivity (mean across profiles = 0.84). The proposed approach, consequently, allows generating of audiologically plausible and interpretable, data-driven clinical auditory profiles, providing an efficient way of characterizing hearing deficits, while maintaining clinical applicability. The method should by design be applicable to all audiological data sets from clinics or research, and in addition be flexible to summarize information across databases by means of profiles, as well as to expand the approach toward aided measurements, fitting parameters, and further information from databases.

Verified
Journal Article
Open access
PDF file
Perrine MorvanPerrine Morvan
Perrine Morvan
JBJohanna Buisson-Savin
Johanna Buisson-Savin
CBCatherine Boiteux
Catherine Boiteux
EBEric Bailly-Masson
Eric Bailly-Masson
MBMareike Buhl
Mareike Buhl
HTHung Thai-Van
Hung Thai-Van
Objectives: Investigate factors contributing to the effective management of age-related hearing loss (ARHL) rehabilitation. Methods: A systematic review was conducted following PRISMA guidelines. The protocol was registered in PROSPERO (CRD42022374811). Articles were identified through systematic searches in the Scopus, PubMed, Web of Science, and Cochrane databases in May 2024. Only articles published between January 2005 and May 2024 were included. Studies were assessed for eligibility by two independent researchers and evaluated using the Crowe Critical Appraisal Tool v1.4 (CCAT). Results: Of the 278 articles identified, 54 were included. Three factors explain effective HA use. First, hearing aid signal processing, with directional microphones and noise reduction, improves user comfort and understanding regarding noise. Second, there is hearing aid fitting, with the NAL prescription rules as the gold standard, and bilateral, high-level HA performance for spatial localization and noise comprehension. Third, there is a patient-centered approach, using patient-related outcome measures (PROMs), questionnaires, counseling, and regular follow-up to involve patients in their therapeutic rehabilitation. Conclusions: Reaching a consensus on acoustic parameters is challenging due to variability in audiological results. Involving patients in their rehabilitation, addressing their needs and expectations, and offering individualized care are crucial.

1 January 2024 in Trends in Hearing
Verified
Journal Article
Open access
CXChen Xu
Chen Xu
DHDavid Hülsmeier
David Hülsmeier
MBMareike Buhl
Mareike Buhl
BKBirger Kollmeier
Birger Kollmeier
Inattention plays a critical role in the accuracy of threshold measurements, e.g., when using mobile devices. To describe the influence of distraction, long- and short-term inattention models based on either a stationary or a non-stationary psychometric function were developed and used to generate three simulated listeners: fully-, moderately-, and non-concentrated listeners. Six established adaptive procedures were assessed via Monte-Carlo simulations in combination with the inattention models and compared with a newly proposed method: the graded response bracketing procedure (GRaBr). Robustness was examined by bias and root mean square error between the “true” and estimated thresholds while efficiency was evaluated using rates of convergence and a normalized efficiency index. The findings show that inattention has a detrimental impact on adaptive procedure performance—especially for the short-term inattentive listener—and that several model-based procedures relying on a consistent response behavior of the listener are prone to errors owing to inattention. The model-free procedure GRaBr, on the other hand, is considerably robust and efficient in spite of the (assumed) inattention. As a result, adaptive techniques with desired properties (i.e., high robustness and efficiency) as revealed in our simulations—such as GRaBr—appear to be advantageous for mobile devices or in laboratory tests with untrained subjects.

11 February 2022 in Diagnostics
Verified
Journal Article
Open access
PDF file
MBMareike Buhl
Mareike Buhl
Common Audiological Functional Parameters (CAFPAs) were previously introduced as abstract, measurement-independent representation of audiological knowledge, and expert-estimated CAFPAs were shown to be applicable as an interpretable intermediate layer in a clinical decision support system (CDSS). Prediction models for CAFPAs were built based on expert knowledge and one audiological database to allow for data-driven estimation of CAFPAs for new, individual patients for whom no expert-estimated CAFPAs are available. Based on the combination of these components, the current study explores the feasibility of constructing a CDSS which is as interpretable as expert knowledge-based classification and as data-driven as machine learning-based classification. To test this hypothesis, the current study investigated the equivalence in performance of predicted CAFPAs compared to expert-estimated CAFPAs in an audiological classification task, analyzed the importance of different CAFPAs for high and comparable performance, and derived explanations for differences in classified categories. Results show that the combination of predicted CAFPAs and statistical classification enables to build an interpretable but data-driven CDSS. The classification provides good accuracy, with most categories being correctly classified, while some confusions can be explained by the properties of the employed database. This could be improved by including additional databases in the CDSS, which is possible within the presented framework.

22 March 2019 in International Journal of Audiology
Verified
Journal Article
Closed access
MBMareike Buhl
Mareike Buhl
Anna WarzybokAnna Warzybok
Anna Warzybok
MSMarc René Schädler
Marc René Schädler
TLThomas Lenarz
Thomas Lenarz
OMOmid Majdani
Omid Majdani
BKBirger Kollmeier
Birger Kollmeier
Objective: As a step towards objectifying audiological rehabilitation and providing comparability between different test batteries and clinics, the Common Audiological Functional Parameters (CAFPAs) were introduced as a common and abstract representation of audiological knowledge obtained from diagnostic tests. Design: Relationships between CAFPAs as an intermediate representation between diagnostic tests and audiological findings, diagnoses and treatment recommendations (summarised as “diagnostic cases”) were established by means of an expert survey. Expert knowledge was collected for 14 given categories covering different diagnostic cases. For each case, the experts were asked to indicate expected ranges of diagnostic test outcomes, as well as traffic light-encoded CAFPAs. Study sample: Eleven German experts in the field of audiological rehabilitation from Hanover and Oldenburg participated in the survey. Results: Audiological findings or treatment recommendations could be distinguished by a statistical model derived from the experts' answers for CAFPAs as well as audiological tests. Conclusions: The CAFPAs serve as an abstract, comprehensive representation of audiological knowledge. If more detailed information on certain functional aspects of the auditory system is required, the CAFPAs indicate which information is missing. The statistical graphical representations for CAFPAs and audiological tests are suitable for audiological teaching material; they are universally applicable for real clinical databases.

24 February 2020 in International Journal of Audiology
Verified
Journal Article
Closed access
MBMareike Buhl
Mareike Buhl
Anna WarzybokAnna Warzybok
Anna Warzybok
MSMarc René Schädler
Marc René Schädler
OMOmid Majdani
Omid Majdani
BKBirger Kollmeier
Birger Kollmeier
Objective: Statistical knowledge about many patients could be exploited using machine learning to provide supporting information to otolaryngologists and other hearing health care professionals, but needs to be made accessible. The Common Audiological Functional Parameters (CAFPAs) were recently introduced for the purpose of integrating data from different databases by providing an abstract representation of audiological measurements. This paper aims at collecting expert labels for a sample database and to determine statistical models from the labelled data set. Design: By an expert survey, CAFPAs as well as labels for audiological findings and treatment recommendations were collected for patients from the database of Hörzentrum Oldenburg. Study sample: A total of 287 single patient cases were assessed by twelve highly experienced audiological experts. Results: The labelled data set was used to derive probability density functions for categories given by the expert labels. The collected data set is suitable for estimating training distributions due to realistic variability contained in data for different, distinct categories. Suitable distribution functions were determined. The derived training distributions were compared regarding different audiological questions. Conclusions: The method-expert survey, sorting data into categories, and determining training distributions – could be extended to other data sets, which could then be integrated via the CAFPAs and used in a classification task.