Isabelle Fournier

Prof. Isabelle Fournier

University of Lille
+1
orcid

Research Focus & Metrics

Academic Career Length

30Years (1997-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
10 February 2007 in Journal of Proteome Research
Verified
Journal Article
Closed access
RLR. Lemaire
R. Lemaire
ADA. Desmons
A. Desmons
JTJ. C. Tabet
J. C. Tabet
RDR. Day
R. Day
MSMichel Salzet
Michel Salzet
IFIsabelle Fournier
Isabelle Fournier

1 March 2010 in Journal of the American Society for Mass Spectrometry
Verified
Journal Article
Closed access
JSJonathan Stauber
Jonathan Stauber
LMLuke MacAleese
Luke MacAleese
JFJulien Franck
Julien Franck
ECEmmanuelle Claude
Emmanuelle Claude
MSMarten Snel
Marten Snel
RHRon M. A. Heeren
Ron M. A. Heeren

16 October 2007 in Journal of Proteome Research
Verified
Journal Article
Closed access
RLRemi Lemaire
Remi Lemaire
SMSonia Ait Menguellet
Sonia Ait Menguellet
JSJonathan Stauber
Jonathan Stauber
VMValerie Marchaudon
Valerie Marchaudon
JLJean-Philippe Lucot
Jean-Philippe Lucot
IFIsabelle Fournier
Isabelle Fournier

13 December 2017 in Frontiers in Pharmacology
Verified
Journal Article
Open access
PDF file
FDFrancesco Drago
Francesco Drago
MLMarta Lombardi
Marta Lombardi
IPIlaria Prada
Ilaria Prada
Martina GabrielliMartina Gabrielli
Martina Gabrielli
PJPooja Joshi
Pooja Joshi
CFChiara Fenoglio
Chiara Fenoglio
Extracellular ATP is among molecules promoting microglia activation and inducing the release of extracellular vesicles (EVs), which are potent mediators of intercellular communication between microglia and the microenvironment. We previously showed that EVs produced under ATP stimulation (ATP-EVs) propagate a robust inflammatory reaction among astrocytes and microglia in vitro and in mice with subclinical neuroinflammation (Verderio et al., 2012). However, the proteome of EVs released upon ATP stimulation has not yet been elucidated. In this study we applied a label free proteomic approach to characterize the proteome of EVs released constitutively and during microglia activation with ATP. We show that ATP drives sorting in EVs of a set of proteins implicated in cell adhesion/extracellular matrix organization, autophagy-lysosomal pathway and cellular metabolism, that may influence the response of recipient astrocytes to EVs. These data provide new clues to molecular mechanisms involved in microglia response to ATP and in microglia signaling to the environment via EVs.

15 September 2006 in Analytical Chemistry
Verified
Journal Article
Closed access
RLR. Lemaire
R. Lemaire
Maxence WisztorskiMaxence Wisztorski
Maxence Wisztorski
ADA. Desmons
A. Desmons
JTJ. C. Tabet
J. C. Tabet
RDR. Day
R. Day
IFIsabelle Fournier
Isabelle Fournier

4 January 2006 in Analytical Chemistry
Verified
Journal Article
Closed access
RLR. Lemaire
R. Lemaire
JTJ. C. Tabet
J. C. Tabet
PDP. Ducoroy
P. Ducoroy
JHJ. B. Hendra
J. B. Hendra
MSMichel Salzet
Michel Salzet
IFIsabelle Fournier
Isabelle Fournier