Dante Trabassi

Dr. Dante Trabassi

Sapienza University of Rome, Rome, Lazio, Italy

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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12 May 2022 in Sensors
Verified
Journal Article
Open access
PDF file
Dante TrabassiDante Trabassi
Dante Trabassi
Mariano SerraoMariano Serrao
Mariano Serrao
TVTiwana VARRECCHIA
Tiwana VARRECCHIA
ARAlberto Ranavolo
Alberto Ranavolo
Gianluca CoppolaGianluca Coppola
Gianluca Coppola
SCStefano Filippo Castiglia
Stefano Filippo Castiglia
The aim of this study was to determine which supervised machine learning (ML) algorithm can most accurately classify people with Parkinson’s disease (pwPD) from speed-matched healthy subjects (HS) based on a selected minimum set of IMU-derived gait features. Twenty-two gait features were extrapolated from the trunk acceleration patterns of 81 pwPD and 80 HS, including spatiotemporal, pelvic kinematics, and acceleration-derived gait stability indexes. After a three-level feature selection procedure, seven gait features were considered for implementing five ML algorithms: support vector machine (SVM), artificial neural network, decision trees (DT), random forest (RF), and K-nearest neighbors. Accuracy, precision, recall, and F1 score were calculated. SVM, DT, and RF showed the best classification performances, with prediction accuracy higher than 80% on the test set. The conceptual model of approaching ML that we proposed could reduce the risk of overrepresenting multicollinear gait features in the model, reducing the risk of overfitting in the test performances while fostering the explainability of the results.

3 June 2024 in Sensors
Verified
Journal Article
Open access
PDF file
Dante TrabassiDante Trabassi
Dante Trabassi
SCStefano Filippo Castiglia
Stefano Filippo Castiglia
Fabiano BiniFabiano Bini
Fabiano Bini
FMFranco Marinozzi
Franco Marinozzi
Arash AjoudaniArash Ajoudani
Arash Ajoudani
Mariano SerraoMariano Serrao
Mariano Serrao
The interpretability of gait analysis studies in people with rare diseases, such as those with primary hereditary cerebellar ataxia (pwCA), is frequently limited by the small sample sizes and unbalanced datasets. The purpose of this study was to assess the effectiveness of data balancing and generative artificial intelligence (AI) algorithms in generating synthetic data reflecting the actual gait abnormalities of pwCA. Gait data of 30 pwCA (age: 51.6 ± 12.2 years; 13 females, 17 males) and 100 healthy subjects (age: 57.1 ± 10.4; 60 females, 40 males) were collected at the lumbar level with an inertial measurement unit. Subsampling, oversampling, synthetic minority oversampling, generative adversarial networks, and conditional tabular generative adversarial networks (ctGAN) were applied to generate datasets to be input to a random forest classifier. Consistency and explainability metrics were also calculated to assess the coherence of the generated dataset with known gait abnormalities of pwCA. ctGAN significantly improved the classification performance compared with the original dataset and traditional data augmentation methods. ctGAN are effective methods for balancing tabular datasets from populations with rare diseases, owing to their ability to improve diagnostic models with consistent explainability.

26 January 2022 in The Cerebellum
Verified
Journal Article
Closed access
PDF file
SCStefano Filippo Castiglia
Stefano Filippo Castiglia
Dante TrabassiDante Trabassi
Dante Trabassi
ATAntonella Tatarelli
Antonella Tatarelli
ARAlberto Ranavolo
Alberto Ranavolo
TVTiwana Varrecchia
Tiwana Varrecchia
MSMariano Serrao
Mariano Serrao

22 May 2023 in Sensors
Verified
Journal Article
Open access
PDF file
SCStefano Filippo Castiglia
Stefano Filippo Castiglia
Dante TrabassiDante Trabassi
Dante Trabassi
CCCarmela Conte
Carmela Conte
ARAlberto Ranavolo
Alberto Ranavolo
Gianluca CoppolaGianluca Coppola
Gianluca Coppola
Mariano SerraoMariano Serrao
Mariano Serrao
The aim of this study was to assess the ability of multiscale sample entropy (MSE), refined composite multiscale entropy (RCMSE), and complexity index (CI) to characterize gait complexity through trunk acceleration patterns in subjects with Parkinson’s disease (swPD) and healthy subjects, regardless of age or gait speed. The trunk acceleration patterns of 51 swPD and 50 healthy subjects (HS) were acquired using a lumbar-mounted magneto-inertial measurement unit during their walking. MSE, RCMSE, and CI were calculated on 2000 data points, using scale factors (τ) 1–6. Differences between swPD and HS were calculated at each τ, and the area under the receiver operating characteristics, optimal cutoff points, post-test probabilities, and diagnostic odds ratios were calculated. MSE, RCMSE, and CIs showed to differentiate swPD from HS. MSE in the anteroposterior direction at τ4 and τ5, and MSE in the ML direction at τ4 showed to characterize the gait disorders of swPD with the best trade-off between positive and negative posttest probabilities and correlated with the motor disability, pelvic kinematics, and stance phase. Using a time series of 2000 data points, a scale factor of 4 or 5 in the MSE procedure can yield the best trade-off in terms of post-test probabilities when compared to other scale factors for detecting gait variability and complexity in swPD.

15 May 2021 in Sensors
Verified
Journal Article
Open access
PDF file
SCStefano Filippo Castiglia
Stefano Filippo Castiglia
ATAntonella Tatarelli
Antonella Tatarelli
Dante TrabassiDante Trabassi
Dante Trabassi
RIRoberto De Icco
Roberto De Icco
VGValentina Grillo
Valentina Grillo
Mariano SerraoMariano Serrao
Mariano Serrao
The aims of this study were to assess the ability of 16 gait indices to identify gait instability and recurrent fallers in persons with Parkinson’s disease (pwPD), regardless of age and gait speed, and to investigate their correlation with clinical and kinematic variables. The trunk acceleration patterns were acquired during the gait of 55 pwPD and 55 age-and-speed matched healthy subjects using an inertial measurement unit. We calculated the harmonic ratios (HR), percent recurrence, and percent determinism (RQAdet), coefficient of variation, normalized jerk score, and the largest Lyapunov exponent for each participant. A value of ≤1.50 for the HR in the antero-posterior direction discriminated between pwPD at Hoehn and Yahr (HY) stage 3 and healthy subjects with a 67% probability, between pwPD at HY 3 and pwPD at lower HY stages with a 73% probability, and it characterized recurrent fallers with a 77% probability. Additionally, HR in the antero-posterior direction was correlated with pelvic obliquity and rotation. RQAdet in the antero-posterior direction discriminated between pwPD and healthy subjects with 67% probability, regardless of the HY stage, and was correlated with stride duration and cadence. Therefore, HR and RQAdet in the antero-posterior direction can both be used as age- and-speed-independent markers of gait instability.

21 July 2022 in Gait & Posture
Verified
Journal Article
Closed access
SCStefano Filippo Castiglia
Stefano Filippo Castiglia
Dante TrabassiDante Trabassi
Dante Trabassi
RIRoberto De Icco
Roberto De Icco
ATAntonella Tatarelli
Antonella Tatarelli
MAMicol Avenali
Micol Avenali
MSMariano Serrao
Mariano Serrao