Pei-Ying Lin

Ms. Pei-Ying Lin

Department of chemistry and center for Nanoscience and Nanotechnology, National Sun Yat-Sen University (NSYSU)
orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2017 in Colloids and Surfaces B: Biointerfaces
Verified
Journal Article
Closed access
MKMei-Lang Kung
Mei-Lang Kung
MTMing-Hong Tai
Ming-Hong Tai
PLPei-Ying Lin
Pei-Ying Lin
DWDeng-Chyang Wu
Deng-Chyang Wu
WWWen-Jeng Wu
Wen-Jeng Wu
Shuchen HsiehShuchen Hsieh
Shuchen Hsieh

Verified
Journal Article
Open access
PDF file
NCNan Fu Chen
Nan Fu Chen
YLYu-Hsiang Liao
Yu-Hsiang Liao
PLPei-Ying Lin
Pei-Ying Lin
WCWu-Fu Chen
Wu-Fu Chen
ZWZhi-Hong Wen
Zhi-Hong Wen
Shuchen HsiehShuchen Hsieh
Shuchen Hsieh
The proliferation of drug-resistant pathogens continues to increase, giving rise to serious public health concerns. Many researchers have formulated metal oxide nanoparticles for use as novel antibacterial agents. In the present study, copper oxide (CuO) was synthesized by simple hydrothermal synthesis, and doping was performed to introduce different polymers onto the NP surface for bacteriostasis optimization. The polymer-modified CuO NPs were analyzed further with XRD, FTIR, TEM, DLS and zeta potential to study their morphology, size, and the charge of the substrate. The results indicate that polymer-modified CuO NPs had a significantly higher bacteriostatic rate than unmodified CuO NPs. In particular, polydopamine (PDA)-modified CuO (CuO-PDA) NPs, which carry a weakly negative surface charge, exhibited excellent antibacterial effects, with a bacteriostatic rate of up to 85.8 ± 0.2% within 3 h. When compared to other polymer-modified CuO NPs, CuO-PDA NPs exhibited superior bacteriostatic activity due to their smaller size, surface charge, and favorable van der Waals interactions. This may be attributed to the fact that the CuO-PDA NPs had relatively lipophilic structures at pH 7.4, which increased their affinity for the lipopolysaccharide-containing outer membrane of the Gram-negative bacterium Escherichia coli.

30 October 2023 in Heliyon
Verified
Journal Article
Open access
Shuchen HsiehShuchen Hsieh
Shuchen Hsieh
PLPei-Ying Lin
Pei-Ying Lin
ILI-Hui Lin
I-Hui Lin
DBDavid E. Beck
David E. Beck
CLChing-Hui Lin
Ching-Hui Lin
Semiconductor development is a major driving force for global economic growth. However, synchronizing it with the Sustainable Development Goals (SDGs) set by the United Nations remains a critical challenge. To gain insight into this, we analyzed SDG-related publications on semiconductors from 2017 to 2022 using the SciVal database. The study found 77,706 documents related to SDGs in the field of semiconductor research, with an overall increase in the number of publications each year. The main focus of these publications was SDG 7 (Affordable and Clean Energy), accounting for 68.9 % of the total publication count. Additionally, the results indicate that semiconductors have multifaceted potential in advancing a range of SDGs. From fostering innovations in healthcare (SDG 3), ensuring clean water access (SDG 6), catalyzing transformative industrial growth (SDG 9), to contributing to climate mitigation strategies (SDG 13), semiconductors emerge as versatile drivers of sustainable development. The respective publication percentages for these goals were 7.3 %, 5.9 %, 9.7 %, and 4.4 %, underscoring their capacity to make substantial contributions across various facets of sustainability. It's worth noting that only 2.9 % of these publications stem from academia-industry collaborations. This indicates a pressing need to facilitate collaboration between academia and industry, as such partnerships have the potential to amplify the impact of semiconductor innovations on the SDGs. The novelty of this study lies in its specific exploration through a comprehensive analysis spanning five years, revealing the alignment between semiconductor advancements and the latest SDGs. It uncovers the significance of collaborative ecosystems involving research institutions, businesses, and governments. Through these results, our study addresses a gap in the existing literature and advances semiconductor contributions to the SDGs.

25 April 2022 in Analytical and Bioanalytical Chemistry
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Journal Article
Closed access
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PLPei-Ying Lin
Pei-Ying Lin
RCRong Chi
Rong Chi
YWYu-Ling Wu
Yu-Ling Wu
AHAnnie Ho
Annie Ho

7 April 2021 in Materials
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Journal Article
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YWYu-Jyuan Wang
Yu-Jyuan Wang
PLPei-Ying Lin
Pei-Ying Lin
Shu-Ling HsiehShu-Ling Hsieh
Shu-Ling Hsieh
RKRajendranath Kirankumar
Rajendranath Kirankumar
HLHsin-Yi Lin
Hsin-Yi Lin
Shuchen HsiehShuchen Hsieh
Shuchen Hsieh
The purpose of this study was to use agar as a multifunctional encapsulating material to allow drug and ferromagnetism to be jointly delivered in one nanoparticle. We successfully encapsulated both Fe3O4 and doxorubicin (DOX) with agar as the drug carrier to obtain DOX-Fe3O4@agar. The iron oxide nanoparticles encapsulated in the carrier maintained good saturation of magnetization (41.9 emu/g) and had superparamagnetism. The heating capacity test showed that the specific absorption rate (SAR) value was 18.9 ± 0.5 W/g, indicating that the ferromagnetic nanoparticles encapsulated in the gel still maintained good heating capacity. Moreover, the magnetocaloric temperature could reach 43 °C in a short period of five minutes. In addition, DOX-Fe3O4@agar reached a maximum release rate of 85% ± 3% in 56 min under a neutral pH 7.0 to simulate the intestinal environment. We found using fluorescent microscopy that DOX entered HT-29 human colon cancer cells and reduced cell viability by 66%. When hyperthermia was induced with an auxiliary external magnetic field, cancer cells could be further killed, with a viability of only 15.4%. These results show that agar is an efficient multiple-drug carrier, and allows controlled drug release. Thus, this synergic treatment has potential application value for biopharmaceutical carrier materials.

27 May 2021 in Applied Sciences
Verified
Journal Article
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HCHisen-Kuo Chin
Hisen-Kuo Chin
PLPei-Ying Lin
Pei-Ying Lin
JCJyunde Chen
Jyunde Chen
RKRajendranath Kirankumar
Rajendranath Kirankumar
ZWZhi-Hong Wen
Zhi-Hong Wen
Shuchen HsiehShuchen Hsieh
Shuchen Hsieh
We demonstrate the development of an active multicomponent Ag/PDA/ZnO@GMF surface-enhanced Raman scattering (SERS) substrate via introducing bio-inspired polydopamine (PDA) in between a noble metal (AgNPs) and ZnO nanorods. The insertion of PDA enabled efficient charge redistribution between metal and semiconductor through their aromatic cores. The substrate exhibited a high enhancement factor (EF) of 1010 for the organic pollutant dye Rhodamine B (RhB). Subsequent exposure of a RhB-loaded substrate to an external UV light source developed an efficient pathway for RhB degradation and replenished the substrate for multiple usage cycles with remarkable photostability. Thus, enhanced performance of the substrate in terms of light-harvesting capability and high charge-separation efficiency was observed. In addition, the much larger surface area of the branched ZnO nanostructures served as a template for PDA assisted synthesis and controlled deposition of AgNPs, which further improved the SERS effect. Our work seeks to understand the contributions of the noble metal and semiconductor components and the synergistic effects of combining them with a facile charge transport medium to enable the fabrication of highly efficient SERS substrates for use in industrial and environmental applications.