Vasiliki Kefala

Vasiliki Kefala


Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
9 August 2024 in Cosmetics
Verified
Journal Article
Open access
PDF file
VGVasiliki Sofia Grech
Vasiliki Sofia Grech
VKVasiliki Kefala
Vasiliki Kefala
EREfstathios Andreas Rallis
Efstathios Andreas Rallis
The integration of artificial intelligence (AI) in cosmetology is transforming the industry in numerous ways, including the introduction of advanced tools such as at-home skin analysis devices that can evaluate skin quality and augmented reality applications that allow users to virtually try on various makeup products. These innovations empower individuals to make well-informed decisions about their cosmetic care and enable cosmetologists to predict treatment outcomes with higher accuracy. In this way, AI enhances patient satisfaction by better aligning expectations with achievable results. A computerized database search was performed to identify articles relevant to this topic. A comprehensive search was applied to the following electronic databases: IEEE Xplore, PubMed, Google Scholar, and Research Gate. This review explores four key areas in the current literature where AI contributes to cosmetic procedures. Firstly, AI democratizes skincare by making products and services more accessible to everyone. Secondly, it bridges the gap between physicians and cosmetic suppliers by enlightening collaboration and innovation. Thirdly, it improves the assessment of cosmetic ingredients by ensuring better safety and efficacy, and lastly, AI provides an ethical alternative to animal testing by replacing the Local Lymph Node Assay (LLNA) and the Guinea Pig Maximization Test (GPMT) with in silico models. While AI offers significant benefits, it also raises concerns about data privacy, informed consent, and the potential for promoting unrealistic beauty standards. Addressing these challenges involves implementing measures such as anonymization and de-identification techniques to protect sensitive data and safeguard informed consent for data collection and processing. This article aims to highlight the responsible and ethical use of AI in cosmetology, emphasizing the importance of accuracy and customization in cosmetic care, which represents a significant advancement in the industry.

7 June 2021 in Cosmetics
Verified
Journal Article
Open access
PDF file
ELENI ANDREOUELENI ANDREOU
ELENI ANDREOU
Sophia HatziantoniouSophia Hatziantoniou
Sophia Hatziantoniou
EREfstathios Andreas Rallis
Efstathios Andreas Rallis
VKVasiliki Kefala
Vasiliki Kefala
The art of tattooing is a popular decorative approach for body decoration and has a corrective value for the face. The tattooing procedure is characterized by placing exogenous pigments into the dermis with a number of needles. The process of creating traditional and cosmetic tattoos is the same. Colorants are deposited in the dermis by piercing the skin with needles of specific shape and thickness, which are moistened with the colorant. Colorants (pigments or dyes) most of the time include impurities which may cause adverse reactions. It is commonly known that tattoo inks remain in the skin for lifetime. It is also a fact that the chemicals that are used in permanent makeup (PMU) colorants may stay in the body for a long time so there is a significant long-term risk for harmful ingredients being placed in the body. Tattoo and PMU colorants contain various substances and their main ingredients and decomposition components may cause health risks and unwanted side effects to skin.

24 November 2023 in Cosmetics
Verified
Journal Article
Open access
PDF file
Paraskevi KalofiriParaskevi Kalofiri
Paraskevi Kalofiri
Foteini BiskanakiFoteini Biskanaki
Foteini Biskanaki
VKVasiliki Kefala
Vasiliki Kefala
NTNiki Tertipi
Niki Tertipi
ΕΣΕλένη Σφύρη
Ελένη Σφύρη
EREfstathios Andreas Rallis
Efstathios Andreas Rallis
Endocrine disruptors (EDs) are molecules capable of mimicking the natural hormones of the body and interfering with the endocrine system in both humans and wildlife. Cosmetic products are one source of EDs; these include an extensive variety of personal care and beauty products designed for the skin and hair, as well as makeup. The widespread use of such products has raised concerns about the presence of EDs within them. In this study, we highlight the issue of EDs and analyze the functioning of the EU regulatory framework for chemicals, specifically those which act as EDs in cosmetic products. We also highlight issues related to the interface between science and policy in the critical area of risk regulation within the EU. In addition, we investigate how chemical substances that act as EDs are identified based on specific criteria and conditions, a process which involves the production and adoption of particular scientific opinions. Finally, we assess the efficiency, suitability, and effectiveness of the regulatory framework in this sensitive area of human exposure to chemicals, especially those that function as EDs.

15 September 2021 in Cosmetics
Verified
Journal Article
Open access
PDF file
KDKATERINA DRAKOU
KATERINA DRAKOU
ATAndrea Tsianni
Andrea Tsianni
FVFaye Vrani
Faye Vrani
VKVasiliki Kefala
Vasiliki Kefala
EREfstathios Andreas Rallis
Efstathios Andreas Rallis
Human skin layers serve as a barrier between the body and the environment, by preventing water loss and blocking the entry of chemicals, allergens, and microbes. Recent data showed that skin lipids are vital ‘key players’ of several functions and mechanisms performing in the skin, such as, barrier function and microbiome composition. Abnormalities in lipid composition have been observed in inflammatory cutaneous diseases with a disrupted skin barrier. This review aims to demonstrate the fundamental role of keratinocytes, sebocytes, and microbiome-derived lipids in the maintenance of the skin barrier. Furthermore, it would reveal the correlation between altered skin lipids’ composition, microbiome, and the occurrence of certain dermatological disorders such as acne vulgaris, atopic dermatitis, psoriasis, and rosacea.

20 May 2024 in Cosmetics
Verified
Journal Article
Open access
PDF file
Sophia LetsiouSophia Letsiou
Sophia Letsiou
EKElpida Koldiri
Elpida Koldiri
Apostolos BeloukasApostolos Beloukas
Apostolos Beloukas
EREfstathios Andreas Rallis
Efstathios Andreas Rallis
VKVasiliki Kefala
Vasiliki Kefala
Sunlight radiation is a fundamental component of our daily lives. Specifically, blue light as well as UV light appear to play a role in the development of oxidative stress, DNA damage, photoaging, and pigmentation through the chromophores in skin tissues. However, several skin problems like psoriasis, eczema, and atopic dermatitis can be avoided with short-duration exposures to low-energy blue light radiation or UV radiation. In addition, exploring the effects of blue light as well as UV radiation on skin is quite essential for the development of minimally invasive antiaging strategies and for the design of innovative cosmetic formulations in modern aesthetics and cosmetology. Thus, in this review, we present the advantages as well as the disadvantages of light radiation, with a special focus on blue light and UV radiation activity on the human skin. We also discuss the molecular action of blue light and UV radiation on human skin. Other types of light radiation are included to holistically approach the effect of light on human skin.

28 August 2023 in Cosmetics
Verified
Journal Article
Open access
PDF file
Foteini BiskanakiFoteini Biskanaki
Foteini Biskanaki
Paraskevi KalofiriParaskevi Kalofiri
Paraskevi Kalofiri
NTNiki Tertipi
Niki Tertipi
ΕΣΕλένη Σφύρη
Ελένη Σφύρη
ELENI ANDREOUELENI ANDREOU
ELENI ANDREOU
EREfstathios Andreas Rallis
Efstathios Andreas Rallis
Food technology, health, nutrition, dermatology, and aesthetics have focused on colorless carotenoids. Carotenoids are readily bioavailable and have demonstrated various health-promoting actions. This article reviews the recent literature concerning carotenoids with the aim to systematize the scattered knowledge on carotenoids and aesthetics. The applications of carotenoids in health-promoting and nutrient products and their potential health effects are discussed. The carotenoids, particularly phytoene and phytofluene, have the unique ability to absorb ultraviolet radiation. Their distinct structures and properties, oxidation sensitivity, stiffness, aggregation tendency, and even fluorescence in the case of phytofluene, contribute to their potential benefits. A diet rich in carotenoid-containing products can positively impact skin health, overall well-being, and the prevention of various diseases. Future studies should focus on generating more data about phytoene and phytofluene levels in the skin to accurately assess skin carotenoid status. This expanding area of research holds promise for the development of novel applications in the fields of health and cosmetics.