This page has only limited features, please log in for full access.

Unclaimed
Francesco De Caro
A.U.O. “San Giovanni di Dio e Ruggi d’Aragona”, 84121 Salerno, Italy

Honors and Awards

The user has no records in this section


Career Timeline

The user has no records in this section.


Short Biography

Professore associato di igiene e medicina preventiva

Following
Followers
Co Authors
The list of users this user is following is empty.
Following: 0 users

Feed

Journal article
Published: 07 June 2021 in Vaccines
Reads 0
Downloads 0

The objectives of this study were to evaluate the psychological factors of health perception, mistrust, anxiety, fear, and indecision of Italians vaccinated against COVID-19, and conduct an analysis of the relationships between these factors and other variables: sex, vaccine priority ministerial categories, and the type and dose of vaccine. The participants included 1564 subjects who joined the vaccination campaign at the COVID-19 Vaccination Center in Salerno, Italy. A survey was conducted in the reference period March–April 2021 using a brief anamnestic questionnaire. In addition, the following standardized scales were used: the State–Trait Anxiety Inventory (STAI-Y) and the Short Form Health Survey (SF-12). The results showed that, in terms of the type of vaccine received, the interviewees felt more confident in having received the Comirnaty (Pfizer-BioNTech, 23.5%) and Vaxzevria (AstraZeneca, 18.6%) vaccines—feeling less tense (2.1%; Vaxzevria (AstraZeneca) = 3.2%), frightened (1%; Vaxzevria (AstraZeneca) = 1.4%), not at all nervous (61.1%; Vaxzevria (AstraZeneca), 43.6%), and not at all/undecided (67.9%; Vaxzevria (AstraZeneca), 58.6%). Regarding the mood and psychological states considered at the different vaccine administration times, other important differences emerged as the interviewees reported higher levels of tension, nervousness, and fear during the first phase of vaccine administration. Specifically, 40.7% (second dose, 32.7%) felt somewhat tense at the first dose, 26.4% felt frightened (second dose, 21.8%), and 33.8% felt nervous (second dose, 26.8%). The perceived state of health also increased at the end of the vaccination cycle, as, at the second dose, 15.4% of the sample reported an evaluation of “excellent” (first dose, 12.4%).

ACS Style

Giuseppina Moccia; Luna Carpinelli; Giulia Savarese; Anna Borrelli; Giovanni Boccia; Oriana Motta; Mario Capunzo; Francesco De Caro. Perception of Health, Mistrust, Anxiety, and Indecision in a Group of Italians Vaccinated against COVID-19. Vaccines 2021, 9, 612 .

AMA Style

Giuseppina Moccia, Luna Carpinelli, Giulia Savarese, Anna Borrelli, Giovanni Boccia, Oriana Motta, Mario Capunzo, Francesco De Caro. Perception of Health, Mistrust, Anxiety, and Indecision in a Group of Italians Vaccinated against COVID-19. Vaccines. 2021; 9 (6):612.

Chicago/Turabian Style

Giuseppina Moccia; Luna Carpinelli; Giulia Savarese; Anna Borrelli; Giovanni Boccia; Oriana Motta; Mario Capunzo; Francesco De Caro. 2021. "Perception of Health, Mistrust, Anxiety, and Indecision in a Group of Italians Vaccinated against COVID-19." Vaccines 9, no. 6: 612.

Journal article
Published: 09 March 2021 in Coronaviruses
Reads 0
Downloads 0

Italy was the first western nation affected by the pandemic and was observed as a pilot case in the management of the new coronavirus epidemic. The outbreak of COVID-19 disease has been challenging in Italy. On June 25, 2020 there were 239,821 total cases, of which 33,592 were deaths nationwide. Three lessons emerged from this experience that can serve as a blueprint to improve future plans for the outbreak of viruses. First, early reports on the spread of COVID-19 can help inform public health officials and medical practitioners in effort to combat its progression; second, inadequate risk assessment related to the urgency of the situation and limited reporting to the virus has led the rapid spread of COVID-19; third, an effective response to the virus had to be undertaken with coherent system of actions simultaneously.

ACS Style

Silvana Mirella Aliberti; Francesco De Caro; Giovanni Boccia; Rosario Caruso; Mario Capunzo. Dealing with COVID-19: Lessons Learned from the Italian Experience. Coronaviruses 2021, 2, 27 -29.

AMA Style

Silvana Mirella Aliberti, Francesco De Caro, Giovanni Boccia, Rosario Caruso, Mario Capunzo. Dealing with COVID-19: Lessons Learned from the Italian Experience. Coronaviruses. 2021; 2 (1):27-29.

Chicago/Turabian Style

Silvana Mirella Aliberti; Francesco De Caro; Giovanni Boccia; Rosario Caruso; Mario Capunzo. 2021. "Dealing with COVID-19: Lessons Learned from the Italian Experience." Coronaviruses 2, no. 1: 27-29.

Journal article
Published: 14 January 2021 in Journal of Public Health Research
Reads 0
Downloads 0

Background: The safety of healthcare workers exposed to formaldehyde remains a great matter of concern for healthcare management units. This work aimed at describing the results of a combined monitoring approach (environmental and biological) to manage occupational exposure to formaldehyde in a hospital setting.Design and Methods: Environmental monitoring of working spaces and biological monitoring of urinary formaldehyde in 16 exposed healthcare workers of the Anatomic Pathology Unit of a University Hospital in Southern Italy was performed on a four-year timescale (2016-2019).Results: Values of aero-dispersed formaldehyde identified were on average low; although workers' urinary formaldehyde levels were also minimal, the statistical analysis highlighted a slight weekly accumulation.Conclusions: Our data confirm that both environmental and biological monitoring are important to identify risk situations, in particular when values of hazardous compounds are below the accepted occupational exposure levels.

ACS Style

Oriana Motta; Bruno Charlier; Francesco De Caro; Albino Coglianese; Federica De Rosa; Giuseppina Moccia; Concetta Pironti; Mario Capunzo; Anna Borrelli; Amelia Filippelli; Viviana Izzo. Environmental and biological monitoring of formaldehyde inside a hospital setting: a combined approach to manage chemical risk in workplaces. Journal of Public Health Research 2021, 10, 1 .

AMA Style

Oriana Motta, Bruno Charlier, Francesco De Caro, Albino Coglianese, Federica De Rosa, Giuseppina Moccia, Concetta Pironti, Mario Capunzo, Anna Borrelli, Amelia Filippelli, Viviana Izzo. Environmental and biological monitoring of formaldehyde inside a hospital setting: a combined approach to manage chemical risk in workplaces. Journal of Public Health Research. 2021; 10 (1):1.

Chicago/Turabian Style

Oriana Motta; Bruno Charlier; Francesco De Caro; Albino Coglianese; Federica De Rosa; Giuseppina Moccia; Concetta Pironti; Mario Capunzo; Anna Borrelli; Amelia Filippelli; Viviana Izzo. 2021. "Environmental and biological monitoring of formaldehyde inside a hospital setting: a combined approach to manage chemical risk in workplaces." Journal of Public Health Research 10, no. 1: 1.

Journal article
Published: 28 November 2020 in Antibiotics
Reads 0
Downloads 0

Bloodstream infections (BSIs) are among the leading causes of morbidity and mortality worldwide, among infectious diseases. Local knowledge of the main bacteria involved in BSIs and their associated antibiotic susceptibility patterns is essential to rationalize the empiric antimicrobial therapy. The aim of this study was to define the incidence of infection and evaluate the antimicrobial resistance profile of the main pathogens involved in BSIs. This study enrolled patients of all ages and both sexes admitted to the University Hospital “San Giovanni di Dio e Ruggi d’Aragona”, Salerno, Italy between January 2015 to December 2019. Bacterial identification and antibiotic susceptibility testing were performed with Vitek 2. A number of 3.949 positive blood cultures were included out of 24,694 total blood cultures from 2015 to 2019. Coagulase-negative staphylococci (CoNS) were identified as the main bacteria that caused BSI (17.4%), followed by Staphylococcus aureus (12.3%), Escherichia coli (10.9%), and Klebsiella pneumoniae (9.4%). Gram-positive bacteria were highly resistant to Penicillin G and Oxacillin, while Gram-negative strains to Ciprofloxacin, Cefotaxime, Ceftazidime, and Amoxicillin-clavulanate. High susceptibility to Vancomycin, Linezolid, and Daptomycin was observed among Gram-positive strains. Fosfomycin showed the best performance to treatment Gram-negative BSIs. Our study found an increase in resistance to the latest generation of antibiotics over the years. This suggests an urgent need to improve antimicrobial management programs to optimize empirical therapy in BSI.

ACS Style

Biagio Santella; Veronica Folliero; Gerarda Maria Pirofalo; Enrica Serretiello; Carla Zannella; Giuseppina Moccia; Emanuela Santoro; Giuseppina Sanna; Oriana Motta; Francesco De Caro; Pasquale Pagliano; Mario Capunzo; Massimiliano Galdiero; Giovanni Boccia; Gianluigi Franci. Sepsis—A Retrospective Cohort Study of Bloodstream Infections. Antibiotics 2020, 9, 851 .

AMA Style

Biagio Santella, Veronica Folliero, Gerarda Maria Pirofalo, Enrica Serretiello, Carla Zannella, Giuseppina Moccia, Emanuela Santoro, Giuseppina Sanna, Oriana Motta, Francesco De Caro, Pasquale Pagliano, Mario Capunzo, Massimiliano Galdiero, Giovanni Boccia, Gianluigi Franci. Sepsis—A Retrospective Cohort Study of Bloodstream Infections. Antibiotics. 2020; 9 (12):851.

Chicago/Turabian Style

Biagio Santella; Veronica Folliero; Gerarda Maria Pirofalo; Enrica Serretiello; Carla Zannella; Giuseppina Moccia; Emanuela Santoro; Giuseppina Sanna; Oriana Motta; Francesco De Caro; Pasquale Pagliano; Mario Capunzo; Massimiliano Galdiero; Giovanni Boccia; Gianluigi Franci. 2020. "Sepsis—A Retrospective Cohort Study of Bloodstream Infections." Antibiotics 9, no. 12: 851.

Journal article
Published: 30 October 2020 in Medicina
Reads 0
Downloads 0

Background and objectives: Ozone has been one of the most investigated and discussed sanitization methods. This paper reports a procedure to sanitize air hospital environments, in particular chirurgical surgery rooms that require high levels of disinfection. The purpose of this work was the development and implementation of a cleansing and sanitizing procedure for critical clinical settings with ozone, to prevent hospital infections by the elimination of all toxic and harmful microorganisms in the air, and ensure safe use for operators and patients. Materials and Methods: The protocol for the study involved a structured selection of a representative environment of healthcare structures such as high, medium, and low-risk settings in air and examples of hospital furniture. Results: The concentration of ozone was measured during sanitization treatment and the estimation of the total microbial count in the air and on different surfaces before and after the sanitization operations was performed. The results demonstrated a significant reduction in the microbial count that always fell below the threshold value. Conclusions: Currently, there are no air treatment strategies available for inactivating airborne organisms during hospital outbreaks, which is most probably due to the lack of approved protocols.

ACS Style

Giuseppina Moccia; Francesco De Caro; Concetta Pironti; Giovanni Boccia; Mario Capunzo; Anna Borrelli; Oriana Motta. Development and Improvement of an Effective Method for Air and Surfaces Disinfection with Ozone Gas as a Decontaminating Agent. Medicina 2020, 56, 578 .

AMA Style

Giuseppina Moccia, Francesco De Caro, Concetta Pironti, Giovanni Boccia, Mario Capunzo, Anna Borrelli, Oriana Motta. Development and Improvement of an Effective Method for Air and Surfaces Disinfection with Ozone Gas as a Decontaminating Agent. Medicina. 2020; 56 (11):578.

Chicago/Turabian Style

Giuseppina Moccia; Francesco De Caro; Concetta Pironti; Giovanni Boccia; Mario Capunzo; Anna Borrelli; Oriana Motta. 2020. "Development and Improvement of an Effective Method for Air and Surfaces Disinfection with Ozone Gas as a Decontaminating Agent." Medicina 56, no. 11: 578.

Journal article
Published: 02 July 2020 in International Journal of Environmental Research and Public Health
Reads 0
Downloads 0

COVID-19 is the disease supported by SARS-CoV-2 infection, which causes a severe form of pneumonia. Due to the pathophysiological characteristics of the COVID-19 syndrome, the particular transmissibility of SARS-CoV-2, and the high globalization of our era, the epidemic emergency from China has spread rapidly all over the world. Human-to-human transmission seems to occur mainly through close contact with symptomatic people affected by COVID-19, and the main way of contagion is via the inhalation of respiratory droplets, for example when patients talk, sneeze or cough. The ability of the virus to survive outside living organisms, in aerosol or on fomites has also been recognized. The dental practitioners are particularly exposed to a high risk of SARS-CoV-2 infection because they cannot always respect the interpersonal distance of more than a meter and are exposed to saliva, blood, and other body fluids during surgical procedures. Moreover, many dental surgeries can generate aerosol, and the risk of airborne infection is to be considered higher. The aim of this paper is to provide practical advice for dentists based on the recent literature, which may be useful in reducing the risk of spreading COVID-19 during clinical practice.

ACS Style

Alessandra Amato; Mario Caggiano; Massimo Amato; Giuseppina Moccia; Mario Capunzo; Francesco De Caro. Infection Control in Dental Practice During the COVID-19 Pandemic. International Journal of Environmental Research and Public Health 2020, 17, 4769 .

AMA Style

Alessandra Amato, Mario Caggiano, Massimo Amato, Giuseppina Moccia, Mario Capunzo, Francesco De Caro. Infection Control in Dental Practice During the COVID-19 Pandemic. International Journal of Environmental Research and Public Health. 2020; 17 (13):4769.

Chicago/Turabian Style

Alessandra Amato; Mario Caggiano; Massimo Amato; Giuseppina Moccia; Mario Capunzo; Francesco De Caro. 2020. "Infection Control in Dental Practice During the COVID-19 Pandemic." International Journal of Environmental Research and Public Health 17, no. 13: 4769.

Journal article
Published: 24 March 2020 in Clinical Infectious Diseases
Reads 0
Downloads 0

To the Editor—We read with great interest the study by Yao et al [1] reporting that hydroxychloroquine has better antiviral activity than chloroquine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is associated with a high lung-to-plasma concentration ratio and immunomodulatory effects. Moreover, the authors highlighted that hydroxychloroquine half maximal effective concentration values “tended to decrease with longer incubation times” and that, in the simulation model, the lung trough concentrations were still above the target concentration on day 10 after a 5-day course of hydroxychloroquine.

ACS Style

Pasquale Pagliano; Ornella Piazza; Francesco DE Caro; Tiziana Ascione; Amelia Filippelli. Is Hydroxychloroquine a Possible Postexposure Prophylaxis Drug to Limit the Transmission to Healthcare Workers Exposed to Coronavirus Disease 2019? Clinical Infectious Diseases 2020, 71, 887 -888.

AMA Style

Pasquale Pagliano, Ornella Piazza, Francesco DE Caro, Tiziana Ascione, Amelia Filippelli. Is Hydroxychloroquine a Possible Postexposure Prophylaxis Drug to Limit the Transmission to Healthcare Workers Exposed to Coronavirus Disease 2019? Clinical Infectious Diseases. 2020; 71 (15):887-888.

Chicago/Turabian Style

Pasquale Pagliano; Ornella Piazza; Francesco DE Caro; Tiziana Ascione; Amelia Filippelli. 2020. "Is Hydroxychloroquine a Possible Postexposure Prophylaxis Drug to Limit the Transmission to Healthcare Workers Exposed to Coronavirus Disease 2019?" Clinical Infectious Diseases 71, no. 15: 887-888.

Review
Published: 28 September 2018 in International Journal of Molecular Sciences
Reads 0
Downloads 0

Diabetes mellitus is a common disease that affects 3–5% of the general population in Italy. In some countries of northern Europe or in North America, it can even affect 6–8% of the population. Of great concern is that the number of cases of diabetes is constantly increasing, probably due to the increase in obesity and the sedentary nature of the population. According to the World Health Organization, in the year 2030 there will be 360 million people with diabetes, compared to 170 million in 2000. This has important repercussions on the lives of patients and their families, and on health systems that offer assistance to patients. In this review, we try to describe in an organized way the pathophysiological continuity between diabetes mellitus, endothelial dysfunction, and platelet hyperaggregation, highlighting the main molecular mechanisms involved and the interconnections.

ACS Style

Albino Carrizzo; Carmine Izzo; Marco Oliveti; Antonia Alfano; Nicola Virtuoso; Mario Capunzo; Paola Di Pietro; Mariaconsiglia Calabrese; Eros De Simone; Sebastiano Sciarretta; Giacomo Frati; Serena Migliarino; Antonio Damato; Mariateresa Ambrosio; Francesco De Caro; Carmine Vecchione. The Main Determinants of Diabetes Mellitus Vascular Complications: Endothelial Dysfunction and Platelet Hyperaggregation. International Journal of Molecular Sciences 2018, 19, 2968 .

AMA Style

Albino Carrizzo, Carmine Izzo, Marco Oliveti, Antonia Alfano, Nicola Virtuoso, Mario Capunzo, Paola Di Pietro, Mariaconsiglia Calabrese, Eros De Simone, Sebastiano Sciarretta, Giacomo Frati, Serena Migliarino, Antonio Damato, Mariateresa Ambrosio, Francesco De Caro, Carmine Vecchione. The Main Determinants of Diabetes Mellitus Vascular Complications: Endothelial Dysfunction and Platelet Hyperaggregation. International Journal of Molecular Sciences. 2018; 19 (10):2968.

Chicago/Turabian Style

Albino Carrizzo; Carmine Izzo; Marco Oliveti; Antonia Alfano; Nicola Virtuoso; Mario Capunzo; Paola Di Pietro; Mariaconsiglia Calabrese; Eros De Simone; Sebastiano Sciarretta; Giacomo Frati; Serena Migliarino; Antonio Damato; Mariateresa Ambrosio; Francesco De Caro; Carmine Vecchione. 2018. "The Main Determinants of Diabetes Mellitus Vascular Complications: Endothelial Dysfunction and Platelet Hyperaggregation." International Journal of Molecular Sciences 19, no. 10: 2968.

Journal article
Published: 01 September 2018 in Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive
Reads 0
Downloads 0
ACS Style

Oriana Motta; Iliana Zarrella; Raffaele Cucciniello; Mario Capunzo; Francesco DE Caro. A new strategy to control the proliferation of microorganisms in solid hospital waste and the diffusion of nosocomial infections. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 2018, 26, 210 -215.

AMA Style

Oriana Motta, Iliana Zarrella, Raffaele Cucciniello, Mario Capunzo, Francesco DE Caro. A new strategy to control the proliferation of microorganisms in solid hospital waste and the diffusion of nosocomial infections. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive. 2018; 26 (3):210-215.

Chicago/Turabian Style

Oriana Motta; Iliana Zarrella; Raffaele Cucciniello; Mario Capunzo; Francesco DE Caro. 2018. "A new strategy to control the proliferation of microorganisms in solid hospital waste and the diffusion of nosocomial infections." Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 26, no. 3: 210-215.

Review
Published: 01 March 2018 in Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive
Reads 0
Downloads 0
ACS Style

Silvano Esposito; Silvana Noviello; Francesco De Caro; Giovanni Boccia. New insights into classification, epidemiology and microbiology of SSTIs, including diabetic foot infections. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 2018, 26, 3 -14.

AMA Style

Silvano Esposito, Silvana Noviello, Francesco De Caro, Giovanni Boccia. New insights into classification, epidemiology and microbiology of SSTIs, including diabetic foot infections. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive. 2018; 26 (1):3-14.

Chicago/Turabian Style

Silvano Esposito; Silvana Noviello; Francesco De Caro; Giovanni Boccia. 2018. "New insights into classification, epidemiology and microbiology of SSTIs, including diabetic foot infections." Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 26, no. 1: 3-14.

Review
Published: 06 February 2018 in International Journal of Molecular Sciences
Reads 0
Downloads 0

A growing number of evidences report that aging represents the major risk factor for the development of cardio and cerebrovascular diseases. Understanding Aging from a genetic, biochemical and physiological point of view could be helpful to design a better medical approach and to elaborate the best therapeutic strategy to adopt, without neglecting all the risk factors associated with advanced age. Of course, the better way should always be understanding risk-to-benefit ratio, maintenance of independence and reduction of symptoms. Although improvements in treatment of cardiovascular diseases in the elderly population have increased the survival rate, several studies are needed to understand the best management option to improve therapeutic outcomes. The aim of this review is to give a 360° panorama on what goes on in the fragile ecosystem of elderly, why it happens and what we can do, right now, with the tools at our disposal to slow down aging, until new discoveries on aging, cardio and cerebrovascular diseases are at hand.

ACS Style

Carmine Izzo; Albino Carrizzo; Antonia Alfano; Nicola Virtuoso; Mario Capunzo; Mariaconsiglia Calabrese; Eros De Simone; Sebastiano Sciarretta; Giacomo Frati; Marco Oliveti; Antonio Damato; Mariateresa Ambrosio; Francesco De Caro; Paolo Remondelli; Carmine Vecchione. The Impact of Aging on Cardio and Cerebrovascular Diseases. International Journal of Molecular Sciences 2018, 19, 481 .

AMA Style

Carmine Izzo, Albino Carrizzo, Antonia Alfano, Nicola Virtuoso, Mario Capunzo, Mariaconsiglia Calabrese, Eros De Simone, Sebastiano Sciarretta, Giacomo Frati, Marco Oliveti, Antonio Damato, Mariateresa Ambrosio, Francesco De Caro, Paolo Remondelli, Carmine Vecchione. The Impact of Aging on Cardio and Cerebrovascular Diseases. International Journal of Molecular Sciences. 2018; 19 (2):481.

Chicago/Turabian Style

Carmine Izzo; Albino Carrizzo; Antonia Alfano; Nicola Virtuoso; Mario Capunzo; Mariaconsiglia Calabrese; Eros De Simone; Sebastiano Sciarretta; Giacomo Frati; Marco Oliveti; Antonio Damato; Mariateresa Ambrosio; Francesco De Caro; Paolo Remondelli; Carmine Vecchione. 2018. "The Impact of Aging on Cardio and Cerebrovascular Diseases." International Journal of Molecular Sciences 19, no. 2: 481.

Journal article
Published: 01 November 2017 in Giornale italiano di medicina del lavoro ed ergonomia
Reads 0
Downloads 0
ACS Style

Ruggero Andrisano-Ruggieri; Pietro Crescenzo; Mario Capunzo; Francesco DE Caro; Riccardo Savastano; Manuela Pennisi; Giovanni Boccia. Understanding the relationship between Sentinel Events and Sources of Work Related Stress for prevention programmes. An Italian survey. Giornale italiano di medicina del lavoro ed ergonomia 2017, 39, 39 -41.

AMA Style

Ruggero Andrisano-Ruggieri, Pietro Crescenzo, Mario Capunzo, Francesco DE Caro, Riccardo Savastano, Manuela Pennisi, Giovanni Boccia. Understanding the relationship between Sentinel Events and Sources of Work Related Stress for prevention programmes. An Italian survey. Giornale italiano di medicina del lavoro ed ergonomia. 2017; 39 (1):39-41.

Chicago/Turabian Style

Ruggero Andrisano-Ruggieri; Pietro Crescenzo; Mario Capunzo; Francesco DE Caro; Riccardo Savastano; Manuela Pennisi; Giovanni Boccia. 2017. "Understanding the relationship between Sentinel Events and Sources of Work Related Stress for prevention programmes. An Italian survey." Giornale italiano di medicina del lavoro ed ergonomia 39, no. 1: 39-41.

Review
Published: 01 September 2017 in Journal of Global Antimicrobial Resistance
Reads 0
Downloads 0

Sepsis and septic shock are common life-threatening pathologies associated with high mortality and substantial costs for healthcare system. Clinical guidelines and bundles for the management of patients with sepsis have recently been updated. Herein, we review the history of sepsis and related conditions definitions from the first consensus conference in 1991 to nowadays, the epidemiologic data resulting from worldwide studies on incidence and mortality, the diagnostic approaches including the microbiological assessment of infection and the use of several prognostic and diagnostic biomarkers and finally we review the main therapeutic measures as the intravenous immunoglobulin therapy and the administration of appropriate antibiotic treatment to provide patients with sepsis a favourable outcome in the antibiotic-resistance era.

ACS Style

Silvano Esposito; Giuseppe De Simone; Giovanni Boccia; Francesco De Caro; Pasquale Pagliano. Sepsis and septic shock: New definitions, new diagnostic and therapeutic approaches. Journal of Global Antimicrobial Resistance 2017, 10, 204 -212.

AMA Style

Silvano Esposito, Giuseppe De Simone, Giovanni Boccia, Francesco De Caro, Pasquale Pagliano. Sepsis and septic shock: New definitions, new diagnostic and therapeutic approaches. Journal of Global Antimicrobial Resistance. 2017; 10 ():204-212.

Chicago/Turabian Style

Silvano Esposito; Giuseppe De Simone; Giovanni Boccia; Francesco De Caro; Pasquale Pagliano. 2017. "Sepsis and septic shock: New definitions, new diagnostic and therapeutic approaches." Journal of Global Antimicrobial Resistance 10, no. : 204-212.

Original paper
Published: 14 June 2017 in Infection
Reads 0
Downloads 0

Meningitis is rarely reported in studies investigating bacterial infections in patients affected by liver cirrhosis. We investigated the findings of bacterial meningitis in patients affected by liver cirrhosis referred to our department in a 16-year period.

ACS Style

Pasquale Pagliano; Giovanni Boccia; Francesco De Caro; Silvano Esposito. Bacterial meningitis complicating the course of liver cirrhosis. Infection 2017, 45, 795 -800.

AMA Style

Pasquale Pagliano, Giovanni Boccia, Francesco De Caro, Silvano Esposito. Bacterial meningitis complicating the course of liver cirrhosis. Infection. 2017; 45 (6):795-800.

Chicago/Turabian Style

Pasquale Pagliano; Giovanni Boccia; Francesco De Caro; Silvano Esposito. 2017. "Bacterial meningitis complicating the course of liver cirrhosis." Infection 45, no. 6: 795-800.

Review
Published: 01 June 2017 in Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive
Reads 0
Downloads 0
ACS Style

Tiziana Ascione; Giusy Di Flumeri; Giovanni Boccia; Francesco DE Caro. Infections in patients affected by liver cirrhosis: an update. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 2017, 25, 91 -97.

AMA Style

Tiziana Ascione, Giusy Di Flumeri, Giovanni Boccia, Francesco DE Caro. Infections in patients affected by liver cirrhosis: an update. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive. 2017; 25 (2):91-97.

Chicago/Turabian Style

Tiziana Ascione; Giusy Di Flumeri; Giovanni Boccia; Francesco DE Caro. 2017. "Infections in patients affected by liver cirrhosis: an update." Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 25, no. 2: 91-97.

Review
Published: 01 March 2017 in Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive
Reads 0
Downloads 0
ACS Style

Tiziana Ascione; Giovanni Balato; Giovanni Boccia; Francesco DE Caro. Predictive value of fever following arthroplasty in diagnosing an early infection. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 2017, 25, 3 -7.

AMA Style

Tiziana Ascione, Giovanni Balato, Giovanni Boccia, Francesco DE Caro. Predictive value of fever following arthroplasty in diagnosing an early infection. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive. 2017; 25 (1):3-7.

Chicago/Turabian Style

Tiziana Ascione; Giovanni Balato; Giovanni Boccia; Francesco DE Caro. 2017. "Predictive value of fever following arthroplasty in diagnosing an early infection." Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 25, no. 1: 3-7.

Journal article
Published: 01 March 2017 in Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive
Reads 0
Downloads 0
ACS Style

Alessandro Sanduzzi; Ilaria Marchetiello; Marialuisa Bocchino; Giovanni Boccia; Francesco DE Caro. Tuberculin skin test and/or interferon gamma release assay: is it still time to debate? Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 2017, 25, 80 -81.

AMA Style

Alessandro Sanduzzi, Ilaria Marchetiello, Marialuisa Bocchino, Giovanni Boccia, Francesco DE Caro. Tuberculin skin test and/or interferon gamma release assay: is it still time to debate? Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive. 2017; 25 (1):80-81.

Chicago/Turabian Style

Alessandro Sanduzzi; Ilaria Marchetiello; Marialuisa Bocchino; Giovanni Boccia; Francesco DE Caro. 2017. "Tuberculin skin test and/or interferon gamma release assay: is it still time to debate?" Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 25, no. 1: 80-81.

Review
Published: 01 December 2016 in Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive
Reads 0
Downloads 0
ACS Style

Pasquale Pagliano; Tiziana Ascione; Giusy Di Flumeri; Giovanni Boccia; Francesco DE Caro. Visceral leishmaniasis in immunocompromised: diagnostic and therapeutic approach and evaluation of the recently released IDSA guidelines. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 2016, 24, 265 -271.

AMA Style

Pasquale Pagliano, Tiziana Ascione, Giusy Di Flumeri, Giovanni Boccia, Francesco DE Caro. Visceral leishmaniasis in immunocompromised: diagnostic and therapeutic approach and evaluation of the recently released IDSA guidelines. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive. 2016; 24 (4):265-271.

Chicago/Turabian Style

Pasquale Pagliano; Tiziana Ascione; Giusy Di Flumeri; Giovanni Boccia; Francesco DE Caro. 2016. "Visceral leishmaniasis in immunocompromised: diagnostic and therapeutic approach and evaluation of the recently released IDSA guidelines." Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 24, no. 4: 265-271.

Case reports
Published: 01 September 2016 in Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive
Reads 0
Downloads 0
ACS Style

Pasquale Pagliano; Tiziana Ascione; Maria Aurora Carleo; Giovanni Boccia; Francesco De Caro; Fabio Tortora. HIV positive patient with HSV-2 encephalitis: case report. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 2016, 24, 1 .

AMA Style

Pasquale Pagliano, Tiziana Ascione, Maria Aurora Carleo, Giovanni Boccia, Francesco De Caro, Fabio Tortora. HIV positive patient with HSV-2 encephalitis: case report. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive. 2016; 24 (3):1.

Chicago/Turabian Style

Pasquale Pagliano; Tiziana Ascione; Maria Aurora Carleo; Giovanni Boccia; Francesco De Caro; Fabio Tortora. 2016. "HIV positive patient with HSV-2 encephalitis: case report." Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 24, no. 3: 1.

Antimicrobial original research paper
Published: 04 July 2016 in Journal of Chemotherapy
Reads 0
Downloads 0

Thirty-two patients affected by SSTIs including DFIs were enrolled between 2013 and 2014. Superficial swab was obtained before and after cleansing with sterile saline, and after ultrasonic debridement; deep tissue biopsy was obtained from ulcer base. Samples were diluted with 1 mL of saline, serial 10-fold dilutions to 10−6 were made and 50 μL of each dilution was plated onto appropriate media. Bacteria were identified by Vitek II system. Microbial load was expressed as CFU/mL. Statistical analysis was performed by χ2. Incidence of Gram positives was higher than Gram negatives (S. aureus and P. aeruginosa being the most frequent); concordance (same bacteria isolated before and after debridement) never exceeded 60%. Ultrasonic debridement significantly reduced bacterial load or even suppressed bacterial growth. While reliability of superficial swab is poor for microbiological diagnosis of SSTIs, swabbing after ultrasonic debridement and biopsy of the ulcer base may be equally reliable.

ACS Style

Silvano Esposito; Giuseppe De Simone; Renato Gioia; Silvana Noviello; Domenico Pagliara; Nicola Campitiello; Corrado Rubino; Dante Lo Pardo; Giovanni Boccia; Francesco DE Caro; Tiziana Ascione. Deep tissue biopsy vs. superficial swab culture, including microbial loading determination, in the microbiological assessment of Skin and Soft Tissue Infections (SSTIs). Journal of Chemotherapy 2016, 29, 154 -158.

AMA Style

Silvano Esposito, Giuseppe De Simone, Renato Gioia, Silvana Noviello, Domenico Pagliara, Nicola Campitiello, Corrado Rubino, Dante Lo Pardo, Giovanni Boccia, Francesco DE Caro, Tiziana Ascione. Deep tissue biopsy vs. superficial swab culture, including microbial loading determination, in the microbiological assessment of Skin and Soft Tissue Infections (SSTIs). Journal of Chemotherapy. 2016; 29 (3):154-158.

Chicago/Turabian Style

Silvano Esposito; Giuseppe De Simone; Renato Gioia; Silvana Noviello; Domenico Pagliara; Nicola Campitiello; Corrado Rubino; Dante Lo Pardo; Giovanni Boccia; Francesco DE Caro; Tiziana Ascione. 2016. "Deep tissue biopsy vs. superficial swab culture, including microbial loading determination, in the microbiological assessment of Skin and Soft Tissue Infections (SSTIs)." Journal of Chemotherapy 29, no. 3: 154-158.