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Gram-negative bacteria release Outer Membrane Vesicles (OMVs) into the extracellular environment. Recent studies recognized these vesicles as vectors to horizontal gene transfer; however, the parameters that mediate OMVs transfer within bacterial communities remain unclear. The present study highlights for the first time the transfer of plasmids containing resistance genes via OMVs derived from Klebsiella pneumoniae (K. pneumoniae). This mechanism confers DNA protection, it is plasmid copy number dependent with a ratio of 3.6 times among high copy number plasmid (pGR) versus low copy number plasmid (PRM), and the transformation efficiency was 3.6 times greater. Therefore, the DNA amount in the vesicular lumen and the efficacy of horizontal gene transfer was strictly dependent on the identity of the plasmid. Moreover, the role of K. pneumoniae-OMVs in interspecies transfer was described. The transfer ability was not related to the phylogenetic characteristics between the donor and the recipient species. K. pneumoniae-OMVs transferred plasmid to Escherichia coli, Salmonella enterica, Pseudomonas aeruginosa and Burkholderia cepacia. These findings address the pivotal role of K. pneumoniae-OMVs as vectors for antimicrobial resistance genes spread, contributing to the development of antibiotic resistance in the microbial communities.
Federica Dell’Annunziata; Carmela Dell’Aversana; Nunzianna Doti; Giuliana Donadio; Fabrizio Dal Piaz; Viviana Izzo; Anna De Filippis; Marilena Galdiero; Lucia Altucci; Giovanni Boccia; Massimiliano Galdiero; Veronica Folliero; Gianluigi Franci. Outer Membrane Vesicles Derived from Klebsiella pneumoniae Are a Driving Force for Horizontal Gene Transfer. International Journal of Molecular Sciences 2021, 22, 8732 .
AMA StyleFederica Dell’Annunziata, Carmela Dell’Aversana, Nunzianna Doti, Giuliana Donadio, Fabrizio Dal Piaz, Viviana Izzo, Anna De Filippis, Marilena Galdiero, Lucia Altucci, Giovanni Boccia, Massimiliano Galdiero, Veronica Folliero, Gianluigi Franci. Outer Membrane Vesicles Derived from Klebsiella pneumoniae Are a Driving Force for Horizontal Gene Transfer. International Journal of Molecular Sciences. 2021; 22 (16):8732.
Chicago/Turabian StyleFederica Dell’Annunziata; Carmela Dell’Aversana; Nunzianna Doti; Giuliana Donadio; Fabrizio Dal Piaz; Viviana Izzo; Anna De Filippis; Marilena Galdiero; Lucia Altucci; Giovanni Boccia; Massimiliano Galdiero; Veronica Folliero; Gianluigi Franci. 2021. "Outer Membrane Vesicles Derived from Klebsiella pneumoniae Are a Driving Force for Horizontal Gene Transfer." International Journal of Molecular Sciences 22, no. 16: 8732.
In recent years, the sanitization of environments, devices, and objects has become mandatory to improve human and environmental safety, in addition to individual protection and prevention measures. International studies considered ozone one of the most useful and easy sanitization methods for indoor environments, especially hospital environments that require adequate levels of disinfection. The purpose of this work was to evaluate the microclimate influence on sanitizing procedure for indoor settings with ozone, to prevent infections and ensure the safe use of the environments. The concentration of ozone was measured during sanitization treatment and estimation of microorganisms’ survival on the air and different contaminated plates after the sanitization operations were performed. The results demonstrated a significant reduction in the microbial count that always fell below the threshold value in different conditions of distance, temperature, and relative humidity.
Concetta Pironti; Giuseppina Moccia; Oriana Motta; Giovanni Boccia; Gianluigi Franci; Emanuela Santoro; Mario Capunzo; Francesco De Caro. The influence of microclimate conditions on ozone disinfection efficacy in working places. Environmental Science and Pollution Research 2021, 1 -6.
AMA StyleConcetta Pironti, Giuseppina Moccia, Oriana Motta, Giovanni Boccia, Gianluigi Franci, Emanuela Santoro, Mario Capunzo, Francesco De Caro. The influence of microclimate conditions on ozone disinfection efficacy in working places. Environmental Science and Pollution Research. 2021; ():1-6.
Chicago/Turabian StyleConcetta Pironti; Giuseppina Moccia; Oriana Motta; Giovanni Boccia; Gianluigi Franci; Emanuela Santoro; Mario Capunzo; Francesco De Caro. 2021. "The influence of microclimate conditions on ozone disinfection efficacy in working places." Environmental Science and Pollution Research , no. : 1-6.
In 2020, a global pandemic was declared following the spread of SARS-CoV-2, the pathogen responsible for COVID-19. The risk of infection is high due to the ease of transmission, which can occur orally, through droplets, or via contact with contaminated surfaces and objects. It has also been demonstrated that the ocular surface can constitute a transmission route, especially in hospital settings, where health care workers can become a dangerous source of infection. In order to increase prevention and reduce the spread of the virus on the ocular surface, the antiviral activity of already-marketed eye drops against SARS-CoV-2 was evaluated. Iodim, Ozodrop, Septavis, and Dropsept were tested against SARS-CoV-2 in plaque-assay experiments at different stimulation times. Furthermore, the expression levels of early and late genes were evaluated through molecular assays. Results indicated that three of the four ophthalmic solutions showed a considerable dose-dependent inhibition of viral replication, highlighting their use as potential antiviral drugs against SARS-CoV-2 and preventing other ocular infections.
Francesco Petrillo; Annalisa Chianese; Maddalena De Bernardo; Carla Zannella; Marilena Galdiero; Michele Reibaldi; Teresio Avitabile; Giovanni Boccia; Massimiliano Galdiero; Nicola Rosa; Gianluigi Franci. Inhibitory Effect of Ophthalmic Solutions against SARS-CoV-2: A Preventive Action to Block the Viral Transmission? Microorganisms 2021, 9, 1550 .
AMA StyleFrancesco Petrillo, Annalisa Chianese, Maddalena De Bernardo, Carla Zannella, Marilena Galdiero, Michele Reibaldi, Teresio Avitabile, Giovanni Boccia, Massimiliano Galdiero, Nicola Rosa, Gianluigi Franci. Inhibitory Effect of Ophthalmic Solutions against SARS-CoV-2: A Preventive Action to Block the Viral Transmission? Microorganisms. 2021; 9 (8):1550.
Chicago/Turabian StyleFrancesco Petrillo; Annalisa Chianese; Maddalena De Bernardo; Carla Zannella; Marilena Galdiero; Michele Reibaldi; Teresio Avitabile; Giovanni Boccia; Massimiliano Galdiero; Nicola Rosa; Gianluigi Franci. 2021. "Inhibitory Effect of Ophthalmic Solutions against SARS-CoV-2: A Preventive Action to Block the Viral Transmission?" Microorganisms 9, no. 8: 1550.
Lower respiratory tract infections (LRTIs) are the most common infections in humans. It is estimated that 2.74 million deaths worldwide occur each year due to LRTIs. The aim of the study was to determine the frequency and antibiotic susceptibility pattern of microorganisms isolated from respiratory samples of patients with LRTIs. Between January 2015 and December 2019, a total of 7038 sputum and bronchoaspirate samples from suspected LRTI patients were collected. Among them, 2753 samples (39.1%) showed significant microbial growth on culture media. The LRTI rate was higher in patients with male gender (67.1%) and with age between 40–59 years (48.6%). The microorganism identification and antibiotic susceptibility testing were performed with Vitek 2. Out of 4278 isolates species, 3102 (72.5%) were Gram-negative bacteria, 1048 (24.5%) were Gram-positive bacteria, and 128 (3.0%) were Candida spp. Major microorganisms isolated were Acinetobacter baumannii (18.6%), Staphylococcus aureus (15.2%), Pseudomonas aeruginosa (14.2%), and Klebsiella pneumoniae (10.9%). In antimicrobial susceptibility testing, Staphylococcus aureus isolates were mostly resistant to Penicillin G (84.1%) and Oxacillin (48.1%), whereas they demonstrated maximum sensitivity to Tigecycline (100%) and Linezolid (99.5%). Among Gram-negative isolates, Acinetobacter baumannii showed maximum sensitivity to Colistin but was resistant to other antibiotics (95–99%). Klebsiella pneumoniae isolates were mostly resistant to Cefotaxime (72.7%) and sensitive to Gentamicin (54.3%), and Pseudomonas aeruginosa was resistant to Ciprofloxacin (40.3%) and sensitive to Amikacin (85.9%). Gram-negative bacteria represented the species most commonly isolated. A high rate of antimicrobial resistance was observed in this study. In conclusion, the correct identification of causative microorganisms and their susceptibility patterns to antibiotics is crucial for choosing targeted and effective antibiotic therapy in LRTIs, and to prevent the emergence of multidrug-resistant bacteria.
Biagio Santella; Enrica Serretiello; Anna De Filippis; Veronica Folliero; Domenico Iervolino; Federica Dell’Annunziata; Roberta Manente; Francesco Valitutti; Emanuela Santoro; Pasquale Pagliano; Massimiliano Galdiero; Giovanni Boccia; Gianluigi Franci. Lower Respiratory Tract Pathogens and Their Antimicrobial Susceptibility Pattern: A 5-Year Study. Antibiotics 2021, 10, 851 .
AMA StyleBiagio Santella, Enrica Serretiello, Anna De Filippis, Veronica Folliero, Domenico Iervolino, Federica Dell’Annunziata, Roberta Manente, Francesco Valitutti, Emanuela Santoro, Pasquale Pagliano, Massimiliano Galdiero, Giovanni Boccia, Gianluigi Franci. Lower Respiratory Tract Pathogens and Their Antimicrobial Susceptibility Pattern: A 5-Year Study. Antibiotics. 2021; 10 (7):851.
Chicago/Turabian StyleBiagio Santella; Enrica Serretiello; Anna De Filippis; Veronica Folliero; Domenico Iervolino; Federica Dell’Annunziata; Roberta Manente; Francesco Valitutti; Emanuela Santoro; Pasquale Pagliano; Massimiliano Galdiero; Giovanni Boccia; Gianluigi Franci. 2021. "Lower Respiratory Tract Pathogens and Their Antimicrobial Susceptibility Pattern: A 5-Year Study." Antibiotics 10, no. 7: 851.
The objectives of this study were to evaluate the psychological factors of health perception, mistrust, anxiety, fear, and indecision of Italians vaccinated against COVID-19, and conduct an analysis of the relationships between these factors and other variables: sex, vaccine priority ministerial categories, and the type and dose of vaccine. The participants included 1564 subjects who joined the vaccination campaign at the COVID-19 Vaccination Center in Salerno, Italy. A survey was conducted in the reference period March–April 2021 using a brief anamnestic questionnaire. In addition, the following standardized scales were used: the State–Trait Anxiety Inventory (STAI-Y) and the Short Form Health Survey (SF-12). The results showed that, in terms of the type of vaccine received, the interviewees felt more confident in having received the Comirnaty (Pfizer-BioNTech, 23.5%) and Vaxzevria (AstraZeneca, 18.6%) vaccines—feeling less tense (2.1%; Vaxzevria (AstraZeneca) = 3.2%), frightened (1%; Vaxzevria (AstraZeneca) = 1.4%), not at all nervous (61.1%; Vaxzevria (AstraZeneca), 43.6%), and not at all/undecided (67.9%; Vaxzevria (AstraZeneca), 58.6%). Regarding the mood and psychological states considered at the different vaccine administration times, other important differences emerged as the interviewees reported higher levels of tension, nervousness, and fear during the first phase of vaccine administration. Specifically, 40.7% (second dose, 32.7%) felt somewhat tense at the first dose, 26.4% felt frightened (second dose, 21.8%), and 33.8% felt nervous (second dose, 26.8%). The perceived state of health also increased at the end of the vaccination cycle, as, at the second dose, 15.4% of the sample reported an evaluation of “excellent” (first dose, 12.4%).
Giuseppina Moccia; Luna Carpinelli; Giulia Savarese; Anna Borrelli; Giovanni Boccia; Oriana Motta; Mario Capunzo; Francesco De Caro. Perception of Health, Mistrust, Anxiety, and Indecision in a Group of Italians Vaccinated against COVID-19. Vaccines 2021, 9, 612 .
AMA StyleGiuseppina Moccia, Luna Carpinelli, Giulia Savarese, Anna Borrelli, Giovanni Boccia, Oriana Motta, Mario Capunzo, Francesco De Caro. Perception of Health, Mistrust, Anxiety, and Indecision in a Group of Italians Vaccinated against COVID-19. Vaccines. 2021; 9 (6):612.
Chicago/Turabian StyleGiuseppina Moccia; Luna Carpinelli; Giulia Savarese; Anna Borrelli; Giovanni Boccia; Oriana Motta; Mario Capunzo; Francesco De Caro. 2021. "Perception of Health, Mistrust, Anxiety, and Indecision in a Group of Italians Vaccinated against COVID-19." Vaccines 9, no. 6: 612.
Ocular bacterial infections represent a serious problem that affecting people of all age and genders. These infections can lead to visual impairment and blindness if not properly treated. The current study evaluates the antimicrobial resistance profiles and the resistance trend of both Staphylococcus aureus (S. aureus) and coagulase-negative staphylococci (CoNS), the main pathogens involved in eye infections. A total of 322 isolates of S. aureus and CoNS, were collected from patients with bacterial conjunctivitis and keratitis at the “Luigi Vanvitelli” University Hospital of Campania in Naples, Italy, between 2017 and 2020. The isolated bacteria showed a high percentage of resistance to methicillin and other antibiotics commonly used for the treatment of ocular infections. Trends in antibiotic resistance were not encouraging, recording—especially among CoNS strains—an increase of more than 20% in resistance to methicillin and aminoglycosides during the study period. Instead, the resistance rates to tetracycline had a significant decrease in CoNS isolates while no changes in their susceptibility to fluoroquinolones and macrolides were observed. However, all isolates showed no resistance to trimethoprim/sulfamethoxazole and chloramphenicol. In this scenario, preventive identification of the infection causative agents and the evaluation of the antimicrobial susceptibility patterns are essential to set up an ocular infection effective drug treatment and also prevent antibiotic resistance.
Francesco Petrillo; Danilo Pignataro; Federica Di Lella; Michele Reibaldi; Matteo Fallico; Niccolò Castellino; Guglielmo Parisi; Maria Trotta; Michele D’Amico; Biagio Santella; Veronica Folliero; Maria Della Rocca; Michele Rinaldi; Gianluigi Franci; Teresio Avitabile; Marilena Galdiero; Giovanni Boccia. Antimicrobial Susceptibility Patterns and Resistance Trends of Staphylococcus aureus and Coagulase-Negative Staphylococci Strains Isolated from Ocular Infections. Antibiotics 2021, 10, 527 .
AMA StyleFrancesco Petrillo, Danilo Pignataro, Federica Di Lella, Michele Reibaldi, Matteo Fallico, Niccolò Castellino, Guglielmo Parisi, Maria Trotta, Michele D’Amico, Biagio Santella, Veronica Folliero, Maria Della Rocca, Michele Rinaldi, Gianluigi Franci, Teresio Avitabile, Marilena Galdiero, Giovanni Boccia. Antimicrobial Susceptibility Patterns and Resistance Trends of Staphylococcus aureus and Coagulase-Negative Staphylococci Strains Isolated from Ocular Infections. Antibiotics. 2021; 10 (5):527.
Chicago/Turabian StyleFrancesco Petrillo; Danilo Pignataro; Federica Di Lella; Michele Reibaldi; Matteo Fallico; Niccolò Castellino; Guglielmo Parisi; Maria Trotta; Michele D’Amico; Biagio Santella; Veronica Folliero; Maria Della Rocca; Michele Rinaldi; Gianluigi Franci; Teresio Avitabile; Marilena Galdiero; Giovanni Boccia. 2021. "Antimicrobial Susceptibility Patterns and Resistance Trends of Staphylococcus aureus and Coagulase-Negative Staphylococci Strains Isolated from Ocular Infections." Antibiotics 10, no. 5: 527.
The onset of the new SARS-CoV-2 coronavirus encouraged the development of new serologic tests that could be additional and complementary to real-time RT-PCR-based assays. In such a context, the study of performances of available tests is urgently needed, as their use has just been initiated for seroprevalence assessment. The aim of this study was to compare four chemiluminescence immunoassays and one immunochromatography test for SARS-Cov-2 antibodies for the evaluation of the degree of diffusion of SARS-CoV-2 infection in Salerno Province (Campania Region, Italy). A total of 3,185 specimens from citizens were tested for anti-SARS-CoV-2 antibodies as part of a screening program. Four automated immunoassays (Abbott and Liaison SARS-CoV-2 CLIA IgG and Roche and Siemens SARS-CoV-2 CLIA IgM/IgG/IgA assays) and one lateral flow immunoassay (LFIA Technogenetics IgG–IgM COVID-19) were used. Seroprevalence in the entire cohort was 2.41, 2.10, 1.82, and 1.85% according to the Liaison IgG, Abbott IgG, Siemens, and Roche total Ig tests, respectively. When we explored the agreement among the rapid tests and the serologic assays, we reported good agreement for Abbott, Siemens, and Roche (Cohen's Kappa coefficient 0.69, 0.67, and 0.67, respectively), whereas we found moderate agreement for Liaison (Cohen's kappa coefficient 0.58). Our study showed that Abbott and Liaison SARS-CoV-2 CLIA IgG, Roche and Siemens SARS-CoV-2 CLIA IgM/IgG/IgA assays, and LFIA Technogenetics IgG-IgM COVID-19 have good agreement in seroprevalence assessment. In addition, our findings indicate that the prevalence of IgG and total Ig antibodies against SARS-CoV-2 at the time of the study was as low as around 3%, likely explaining the amplitude of the current second wave.
Pellegrino Cerino; Alfonso Gallo; Biancamaria Pierri; Carlo Buonerba; Denise Di Concilio; Maria Concetta Cuomo; Lucia Vassallo; Gabriella Lo Conte; AnnaChiara Coppola; Antonio Pizzolante; Giovanni Boccia; Veronica Ferrucci; Luigi Atripaldi; Maria Triassi; Daniela Pacella; Michele Cennamo; Paolo Romano; Teresa Maria Sorbo; Alessandro Furno; Oriana Catapano; Aldo Contina; Giuseppe Perruolo; Maurizio D'Amora; Daniela Terracciano; Giuseppe Portella. Seroprevalence of SARS-CoV-2 Assessed by Four Chemiluminescence Immunoassays and One Immunocromatography Test for SARS-Cov-2. Frontiers in Public Health 2021, 9, 649781 .
AMA StylePellegrino Cerino, Alfonso Gallo, Biancamaria Pierri, Carlo Buonerba, Denise Di Concilio, Maria Concetta Cuomo, Lucia Vassallo, Gabriella Lo Conte, AnnaChiara Coppola, Antonio Pizzolante, Giovanni Boccia, Veronica Ferrucci, Luigi Atripaldi, Maria Triassi, Daniela Pacella, Michele Cennamo, Paolo Romano, Teresa Maria Sorbo, Alessandro Furno, Oriana Catapano, Aldo Contina, Giuseppe Perruolo, Maurizio D'Amora, Daniela Terracciano, Giuseppe Portella. Seroprevalence of SARS-CoV-2 Assessed by Four Chemiluminescence Immunoassays and One Immunocromatography Test for SARS-Cov-2. Frontiers in Public Health. 2021; 9 ():649781.
Chicago/Turabian StylePellegrino Cerino; Alfonso Gallo; Biancamaria Pierri; Carlo Buonerba; Denise Di Concilio; Maria Concetta Cuomo; Lucia Vassallo; Gabriella Lo Conte; AnnaChiara Coppola; Antonio Pizzolante; Giovanni Boccia; Veronica Ferrucci; Luigi Atripaldi; Maria Triassi; Daniela Pacella; Michele Cennamo; Paolo Romano; Teresa Maria Sorbo; Alessandro Furno; Oriana Catapano; Aldo Contina; Giuseppe Perruolo; Maurizio D'Amora; Daniela Terracciano; Giuseppe Portella. 2021. "Seroprevalence of SARS-CoV-2 Assessed by Four Chemiluminescence Immunoassays and One Immunocromatography Test for SARS-Cov-2." Frontiers in Public Health 9, no. : 649781.
Urinary tract infections (UTIs) are a very widespread infection that can occur in disparate age range, in both sexes and in pregnancy/menopause state. Treatment of UTIs is difficult due to the emergence of antibiotic-resistant bacterial strains. The present study shows five years of data collected on patients admitted at the University Hospital “San Giovann di Dio e Ruggi d’Aragona” in Salerno, Italy. The investigation exhibits the incidence of the infection, of the gender, and of the age group affected, identifying the most representative bacteria involved, drawing their profile of antimicrobial resistance. Bacterial identification and antibiotic susceptibility testing were performed using the VITEK 2 system. Among the 46382 studied patients, 9896 (21.34%) and 36486 (78.66%) were positive and negative for microorganism growth, respectively. Of 9896 positive patients, 6158 (62.23%) females and 3738 (37.77%) males were identified. The highest incidence of positive subjects (56.66%) was recorded in the elderly (>61 years). 8431 (85.20%) uropathogens were Gram-negative, 1367 (13.81%) were Gram-positive, and 98 (0.99%) were Candida species (Candida spp.). Escherichia coli (E. coli) and Enterococcus faecalis (E. faecalis) were the most representative Gram-negative and Gram-positive strains, respectively. The Gram-negative bacteria most representative were highly resistant to ampicillin, whereas among the Gram-positive bacteria, E. faecalis was highly resistant to gentamicin and streptomycin high level synergy, and Enterococcus faecium (E. faecium) to ampicillin, ampicillin/sulbactam, and imipenem. This retrospective work investigates the local epidemiological trend in our university hospital in order to induce an increasingly targeted empirical therapeutic approach for the treatment of UTIs.
Enrica Serretiello; Veronica Folliero; Biagio Santella; Giuseppina Giordano; E. Santoro; Francesco De Caro; Pasquale Pagliano; Matteo Ferro; Silvana M. Aliberti; Mario Capunzo; Massimiliano Galdiero; Gianluigi Franci; Giovanni Boccia. Trend of Bacterial Uropathogens and Their Susceptibility Pattern: Study of Single Academic High-Volume Center in Italy (2015–2019). International Journal of Microbiology 2021, 2021, 1 -10.
AMA StyleEnrica Serretiello, Veronica Folliero, Biagio Santella, Giuseppina Giordano, E. Santoro, Francesco De Caro, Pasquale Pagliano, Matteo Ferro, Silvana M. Aliberti, Mario Capunzo, Massimiliano Galdiero, Gianluigi Franci, Giovanni Boccia. Trend of Bacterial Uropathogens and Their Susceptibility Pattern: Study of Single Academic High-Volume Center in Italy (2015–2019). International Journal of Microbiology. 2021; 2021 ():1-10.
Chicago/Turabian StyleEnrica Serretiello; Veronica Folliero; Biagio Santella; Giuseppina Giordano; E. Santoro; Francesco De Caro; Pasquale Pagliano; Matteo Ferro; Silvana M. Aliberti; Mario Capunzo; Massimiliano Galdiero; Gianluigi Franci; Giovanni Boccia. 2021. "Trend of Bacterial Uropathogens and Their Susceptibility Pattern: Study of Single Academic High-Volume Center in Italy (2015–2019)." International Journal of Microbiology 2021, no. : 1-10.
Italy was the first western nation affected by the pandemic and was observed as a pilot case in the management of the new coronavirus epidemic. The outbreak of COVID-19 disease has been challenging in Italy. On June 25, 2020 there were 239,821 total cases, of which 33,592 were deaths nationwide. Three lessons emerged from this experience that can serve as a blueprint to improve future plans for the outbreak of viruses. First, early reports on the spread of COVID-19 can help inform public health officials and medical practitioners in effort to combat its progression; second, inadequate risk assessment related to the urgency of the situation and limited reporting to the virus has led the rapid spread of COVID-19; third, an effective response to the virus had to be undertaken with coherent system of actions simultaneously.
Silvana Mirella Aliberti; Francesco De Caro; Giovanni Boccia; Rosario Caruso; Mario Capunzo. Dealing with COVID-19: Lessons Learned from the Italian Experience. Coronaviruses 2021, 2, 27 -29.
AMA StyleSilvana Mirella Aliberti, Francesco De Caro, Giovanni Boccia, Rosario Caruso, Mario Capunzo. Dealing with COVID-19: Lessons Learned from the Italian Experience. Coronaviruses. 2021; 2 (1):27-29.
Chicago/Turabian StyleSilvana Mirella Aliberti; Francesco De Caro; Giovanni Boccia; Rosario Caruso; Mario Capunzo. 2021. "Dealing with COVID-19: Lessons Learned from the Italian Experience." Coronaviruses 2, no. 1: 27-29.
Bloodstream infections (BSIs) are among the leading causes of morbidity and mortality worldwide, among infectious diseases. Local knowledge of the main bacteria involved in BSIs and their associated antibiotic susceptibility patterns is essential to rationalize the empiric antimicrobial therapy. The aim of this study was to define the incidence of infection and evaluate the antimicrobial resistance profile of the main pathogens involved in BSIs. This study enrolled patients of all ages and both sexes admitted to the University Hospital “San Giovanni di Dio e Ruggi d’Aragona”, Salerno, Italy between January 2015 to December 2019. Bacterial identification and antibiotic susceptibility testing were performed with Vitek 2. A number of 3.949 positive blood cultures were included out of 24,694 total blood cultures from 2015 to 2019. Coagulase-negative staphylococci (CoNS) were identified as the main bacteria that caused BSI (17.4%), followed by Staphylococcus aureus (12.3%), Escherichia coli (10.9%), and Klebsiella pneumoniae (9.4%). Gram-positive bacteria were highly resistant to Penicillin G and Oxacillin, while Gram-negative strains to Ciprofloxacin, Cefotaxime, Ceftazidime, and Amoxicillin-clavulanate. High susceptibility to Vancomycin, Linezolid, and Daptomycin was observed among Gram-positive strains. Fosfomycin showed the best performance to treatment Gram-negative BSIs. Our study found an increase in resistance to the latest generation of antibiotics over the years. This suggests an urgent need to improve antimicrobial management programs to optimize empirical therapy in BSI.
Biagio Santella; Veronica Folliero; Gerarda Maria Pirofalo; Enrica Serretiello; Carla Zannella; Giuseppina Moccia; Emanuela Santoro; Giuseppina Sanna; Oriana Motta; Francesco De Caro; Pasquale Pagliano; Mario Capunzo; Massimiliano Galdiero; Giovanni Boccia; Gianluigi Franci. Sepsis—A Retrospective Cohort Study of Bloodstream Infections. Antibiotics 2020, 9, 851 .
AMA StyleBiagio Santella, Veronica Folliero, Gerarda Maria Pirofalo, Enrica Serretiello, Carla Zannella, Giuseppina Moccia, Emanuela Santoro, Giuseppina Sanna, Oriana Motta, Francesco De Caro, Pasquale Pagliano, Mario Capunzo, Massimiliano Galdiero, Giovanni Boccia, Gianluigi Franci. Sepsis—A Retrospective Cohort Study of Bloodstream Infections. Antibiotics. 2020; 9 (12):851.
Chicago/Turabian StyleBiagio Santella; Veronica Folliero; Gerarda Maria Pirofalo; Enrica Serretiello; Carla Zannella; Giuseppina Moccia; Emanuela Santoro; Giuseppina Sanna; Oriana Motta; Francesco De Caro; Pasquale Pagliano; Mario Capunzo; Massimiliano Galdiero; Giovanni Boccia; Gianluigi Franci. 2020. "Sepsis—A Retrospective Cohort Study of Bloodstream Infections." Antibiotics 9, no. 12: 851.
Zusammenfassung Italien war die erste westliche Nation, die von der Pandemie betroffen war, und wurde so zum Vorreiter im Kampf gegen die neue Corona-Epidemie. Der Ausbruch der COVID-19-Krankheit stellte das Land vor große, nicht immer gut bewältigte Aufgaben. Am 15. September 2020 waren landesweit insgesamt 288.723 Personen an COVID-19 erkrankt, von denen 35.641 verstarben. Der Diskussionsbeitrag fragt danach, ob und was wir aus den italienischen Erfahrungen und dem in vielen Ländern unterschiedlichen Umgang mit der Pandemie lernen können. Abstract Italy was the first Western nation to be affected by the pandemic, becoming a pioneer in the fight against the new corona epidemic. The outbreak of COVID-19 disease presented the country with major challenges, which were not always well managed. On September 15, 2020, there were a total of 288,723 cases in Italy, with 35,641 COVID-19 related deaths nationwide. The present paper asks whether there is anything to be learned from the Italian experience and the different ways in which the pandemic is being managed in many countries.
Silvana Mirella Aliberti; Francesco De Caro; Giovanni Boccia; Mario Capunzo. Ist die Corona-Krise eine Lehrmeisterin für die Zukunft? Italienische Erfahrungen im Rahmen weltweiter Diskurse. Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen 2020, 158-159, 16 -21.
AMA StyleSilvana Mirella Aliberti, Francesco De Caro, Giovanni Boccia, Mario Capunzo. Ist die Corona-Krise eine Lehrmeisterin für die Zukunft? Italienische Erfahrungen im Rahmen weltweiter Diskurse. Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen. 2020; 158-159 ():16-21.
Chicago/Turabian StyleSilvana Mirella Aliberti; Francesco De Caro; Giovanni Boccia; Mario Capunzo. 2020. "Ist die Corona-Krise eine Lehrmeisterin für die Zukunft? Italienische Erfahrungen im Rahmen weltweiter Diskurse." Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen 158-159, no. : 16-21.
Background and objectives: Ozone has been one of the most investigated and discussed sanitization methods. This paper reports a procedure to sanitize air hospital environments, in particular chirurgical surgery rooms that require high levels of disinfection. The purpose of this work was the development and implementation of a cleansing and sanitizing procedure for critical clinical settings with ozone, to prevent hospital infections by the elimination of all toxic and harmful microorganisms in the air, and ensure safe use for operators and patients. Materials and Methods: The protocol for the study involved a structured selection of a representative environment of healthcare structures such as high, medium, and low-risk settings in air and examples of hospital furniture. Results: The concentration of ozone was measured during sanitization treatment and the estimation of the total microbial count in the air and on different surfaces before and after the sanitization operations was performed. The results demonstrated a significant reduction in the microbial count that always fell below the threshold value. Conclusions: Currently, there are no air treatment strategies available for inactivating airborne organisms during hospital outbreaks, which is most probably due to the lack of approved protocols.
Giuseppina Moccia; Francesco De Caro; Concetta Pironti; Giovanni Boccia; Mario Capunzo; Anna Borrelli; Oriana Motta. Development and Improvement of an Effective Method for Air and Surfaces Disinfection with Ozone Gas as a Decontaminating Agent. Medicina 2020, 56, 578 .
AMA StyleGiuseppina Moccia, Francesco De Caro, Concetta Pironti, Giovanni Boccia, Mario Capunzo, Anna Borrelli, Oriana Motta. Development and Improvement of an Effective Method for Air and Surfaces Disinfection with Ozone Gas as a Decontaminating Agent. Medicina. 2020; 56 (11):578.
Chicago/Turabian StyleGiuseppina Moccia; Francesco De Caro; Concetta Pironti; Giovanni Boccia; Mario Capunzo; Anna Borrelli; Oriana Motta. 2020. "Development and Improvement of an Effective Method for Air and Surfaces Disinfection with Ozone Gas as a Decontaminating Agent." Medicina 56, no. 11: 578.
Objectives: The aim of this study was to assess the impact of COVID-19 pandemic and population lockdown on pediatric ED consultations. Methods: A cross-sectional study on pediatric emergency department consultations before and during the current COVID-19 pandemic (March -May 2019 vs March - May 2020) was performed in two hospitals in Campania region (Southern Italy), i.e. Salerno University Hospital (Salerno) and Pediatric Regional Referral Emergency Hub “AORN Santobono-Pausillipon” (Naples). Results: 29,368 consecutive ED pediatric patients (13,430 females; mean age ± SD= 5.4 + 4.7)years) were seen in March - May 2019 and 9,133 (4,494 females; mean age ± SD= 5.9 + 4.2 years) in March - May 2020. Resuscitation/emergency and urgent care pediatric ED consultations were 1,388 (4.7%, 95%CI 4.5-4.9) in 2019 trimester, while they were 648 (7.1%, 95% CI 6.6-7.6) in 2020 trimester (p<0.01). Mean pediatric ED daily consultations were 326.3 (95% CI 352.7-299.9) in the considered period of 2019 and 101.4 (95%CI 77.9-124.9) in the same period of 2020 (p<0.001). Covid-19 nasal swabs were performed for 385 children, of those 6 resulted positive and 4 of them were hospitalized. Conclusions: This work provides a unique snapshot of the pediatric EDs demands in the era of COVID-19. We witnessed a significant reduction of non-urgent health care demands during the pandemic but an increase of more severe urgent cases. COVID-19 pandemic and following lockdown unveiled the inappropriateness of the majority of pediatric ED consultations. Nevertheless, current scenario highlighted the need for appropriate and timely clinical evaluations in the pediatric primary care to tackle late and more severe diagnoses in EDs.
Francesco Valitutti; Letizia Zenzeri; Angela Mauro; Rosario Pacifico; Micaela Borrelli; Stefania Muzzica; Giovanni Boccia; Vincenzo Tipo; Pietro Vajro. Effect of Population Lockdown on Pediatric Emergency Room Demands in the Era of COVID-19. Frontiers in Pediatrics 2020, 8, 1 .
AMA StyleFrancesco Valitutti, Letizia Zenzeri, Angela Mauro, Rosario Pacifico, Micaela Borrelli, Stefania Muzzica, Giovanni Boccia, Vincenzo Tipo, Pietro Vajro. Effect of Population Lockdown on Pediatric Emergency Room Demands in the Era of COVID-19. Frontiers in Pediatrics. 2020; 8 ():1.
Chicago/Turabian StyleFrancesco Valitutti; Letizia Zenzeri; Angela Mauro; Rosario Pacifico; Micaela Borrelli; Stefania Muzzica; Giovanni Boccia; Vincenzo Tipo; Pietro Vajro. 2020. "Effect of Population Lockdown on Pediatric Emergency Room Demands in the Era of COVID-19." Frontiers in Pediatrics 8, no. : 1.
Aims: The aim of this study was to investigate the correct use of gloves and alcohol-based products for hand hygiene and identify opportunities for hand hygiene replacement with gloves among healthcare professionals working in the Department of Anesthesia and Intensive Care of a tertiary care University Hospital. Background: Two centuries have passed since the discovery of Semmelweis that the “puerperal fever” was due to an infection transmitted by the hands. Currently the hand hygiene is still not well performed, rather it is often replaced by the improper use of gloves. Microbial transmission is estimated to occur in one-fifth of all contact cases. Objective: To investigate the correct use of gloves and alcohol-based products for hand hygiene and identify opportunities for hand hygiene replacement with gloves among healthcare professionals. Furthermore, to correlate the consumption data of the hydroalcoholic solution and the amount of antibiotics used for the treatment of hospital-acquired infections. Method: The study was conducted over six months period (from January to June 2018); during this period, 20 monitoring sessions were performed. The following indicators were evaluated: a) Non-adherence to hand hygiene with concomitant use of gloves; b) Adhesion to alcoholic friction of hands; c) Hand-washing adhesion. Instead, the consumption data, provided by the hospital ward itself, were used for the evaluation of d) The antibiotics used in the treatment of hospital-acquired infections; e) The hydro-alcoholic solution used by the healthcare professionals for hand hygiene. Results: The frequency of non-adherence to hand hygiene was very high at the beginning of the study, subsequently it decreased to about a half percent to that at the initial stage. The adhesion to alcoholic friction of hands increased during the study period. Otherwise, the hand-washing adhesion slightly reduced, especially in March probably due to the recruitment of new inadequately trained nursing staff. The trend of antibiotic consumption was similar to handwashing. The consumption of hydro-alcoholic solution was very low, however over time, it increased considerably until the end of the study. Conclusion: In light of the findings from this work, it is necessary to make the hospital staff increasingly aware of the correct practice of hand hygiene and to organize training and informative sessions to promote the health of the individual and the community.
Emanuela Santoro; Marco Fiore; Sebastiano Leone; Armando Masucci; Roberta Manente; Marco Guida; Giovanni Libralato; Michela Russo; Valeria Di Onofrio; Mario Capunzo; Giovanni Boccia. Correlation between Antibiotic Consumption and Hand Hygiene Compliance Among Anesthesia and Intensive Care Healthcare Professionals. The Open Anesthesia Journal 2020, 14, 42 -48.
AMA StyleEmanuela Santoro, Marco Fiore, Sebastiano Leone, Armando Masucci, Roberta Manente, Marco Guida, Giovanni Libralato, Michela Russo, Valeria Di Onofrio, Mario Capunzo, Giovanni Boccia. Correlation between Antibiotic Consumption and Hand Hygiene Compliance Among Anesthesia and Intensive Care Healthcare Professionals. The Open Anesthesia Journal. 2020; 14 (1):42-48.
Chicago/Turabian StyleEmanuela Santoro; Marco Fiore; Sebastiano Leone; Armando Masucci; Roberta Manente; Marco Guida; Giovanni Libralato; Michela Russo; Valeria Di Onofrio; Mario Capunzo; Giovanni Boccia. 2020. "Correlation between Antibiotic Consumption and Hand Hygiene Compliance Among Anesthesia and Intensive Care Healthcare Professionals." The Open Anesthesia Journal 14, no. 1: 42-48.
Aim To develop an instrument to investigate knowledge and predictive factors of needlestick and sharps injuries (NSIs) in nursing students during clinical placements. Design Instrument development and cross‐sectional study for psychometric testing. Methods A self‐administered instrument including demographic data, injury epidemiology and predictive factors of NSIs was developed between October 2018–January 2019. Content validity was assessed by a panel of experts. The instrument's factor structure and discriminant validity were explored using principal components analysis. The STROBE guidelines were followed. Results Evidence of content validity was found (S‐CVI 0.75; I‐CVI 0.50–1.00). A three‐factor structure was shown by exploratory factor analysis. Of the 238 participants, 39% had been injured at least once, of which 67.3% in the second year. Higher perceptions of “personal exposure” (4.06, SD 3.78) were reported by third‐year students. Higher scores for “perceived benefits” of preventive behaviours (13.6, SD 1.46) were reported by second‐year students.
Annamaria Bagnasco; Milko Zanini; Gianluca Catania; Roger Watson; Mark Hayter; Nicoletta Dasso; Guglielmo Dini; Antonella Agodi; Cesira Pasquarella; Carla Maria Zotti; Paolo Durando; Loredana Sasso; Martina Barchitta; Andrea Maugeri; Giuliana Favara; Roberta Magnano San Lio; Angelo Rossini; Raffaele Squeri; Cristina Genovese; Smeralda D'Amato; Vincenza La Fauci; Stefano Tardivo; Francesca Moretti; Alberto Carli; Beatrice Casini; Angelo Baggiani; Marco Verani; Anna Rita Giuliani; Leila Fabiani; Silvia D’Eugenio; Giovanni Boccia; Emanuela Santoro; Giovanni Battista Orsi; Christian Napoli; Marzia Montesano; Stefania Berdini; Enrico Bertamino; Antonio Perre; Alessandro Zerbetto; Marcello D’Errico; Sandro Ortolani; Maurizio Mercuri; Tiziana Traini; Adoriano Santarelli; Rita Fiorentini; Tiziana Benedetti; Maria Teresa Montagna; Simona Mascipinto; Ida Torre; Francesca Pennino; Daniela Schiavone; Anna Maria Iannicelli; Edoardo Tartaglia; Licia Veronesi; Lucia Palandri; Mariana Sao Miguel Morgado; Leandra Giudice; Cristina Arrigoni; Leandro Gentile; Barbara Bascapè; Ida Mura; Giovanni Sotgiu; Ilaria Barberis; Francesca Maria Bersi; Alessia Manca; Emanuela Massa; Alfredo Montecucco; Alborz Rahmani; Sonia Zacconi; Matteo Riccò; Nicola Magnavita; Reparata Rosa Di Prinzio; Maria Valeria Torregrossa; Giuseppe Calamusa; Alberto Firenze; Annalisa Bargellini; Paola Ferri; Elena Righi; Elisabetta Carraro; Alberto Borraccino; Deborah Traversi; Maria Chiara Ottino; Tatjana Baldovin; Sara Dalla Torre; Arda Sulaj; Ada Bianco; Valeria Teti; Roberto Novati; Roberta Oriani. Predicting needlestick and sharps injuries in nursing students: Development of the SNNIP scale. Nursing Open 2020, 7, 1578 -1587.
AMA StyleAnnamaria Bagnasco, Milko Zanini, Gianluca Catania, Roger Watson, Mark Hayter, Nicoletta Dasso, Guglielmo Dini, Antonella Agodi, Cesira Pasquarella, Carla Maria Zotti, Paolo Durando, Loredana Sasso, Martina Barchitta, Andrea Maugeri, Giuliana Favara, Roberta Magnano San Lio, Angelo Rossini, Raffaele Squeri, Cristina Genovese, Smeralda D'Amato, Vincenza La Fauci, Stefano Tardivo, Francesca Moretti, Alberto Carli, Beatrice Casini, Angelo Baggiani, Marco Verani, Anna Rita Giuliani, Leila Fabiani, Silvia D’Eugenio, Giovanni Boccia, Emanuela Santoro, Giovanni Battista Orsi, Christian Napoli, Marzia Montesano, Stefania Berdini, Enrico Bertamino, Antonio Perre, Alessandro Zerbetto, Marcello D’Errico, Sandro Ortolani, Maurizio Mercuri, Tiziana Traini, Adoriano Santarelli, Rita Fiorentini, Tiziana Benedetti, Maria Teresa Montagna, Simona Mascipinto, Ida Torre, Francesca Pennino, Daniela Schiavone, Anna Maria Iannicelli, Edoardo Tartaglia, Licia Veronesi, Lucia Palandri, Mariana Sao Miguel Morgado, Leandra Giudice, Cristina Arrigoni, Leandro Gentile, Barbara Bascapè, Ida Mura, Giovanni Sotgiu, Ilaria Barberis, Francesca Maria Bersi, Alessia Manca, Emanuela Massa, Alfredo Montecucco, Alborz Rahmani, Sonia Zacconi, Matteo Riccò, Nicola Magnavita, Reparata Rosa Di Prinzio, Maria Valeria Torregrossa, Giuseppe Calamusa, Alberto Firenze, Annalisa Bargellini, Paola Ferri, Elena Righi, Elisabetta Carraro, Alberto Borraccino, Deborah Traversi, Maria Chiara Ottino, Tatjana Baldovin, Sara Dalla Torre, Arda Sulaj, Ada Bianco, Valeria Teti, Roberto Novati, Roberta Oriani. Predicting needlestick and sharps injuries in nursing students: Development of the SNNIP scale. Nursing Open. 2020; 7 (5):1578-1587.
Chicago/Turabian StyleAnnamaria Bagnasco; Milko Zanini; Gianluca Catania; Roger Watson; Mark Hayter; Nicoletta Dasso; Guglielmo Dini; Antonella Agodi; Cesira Pasquarella; Carla Maria Zotti; Paolo Durando; Loredana Sasso; Martina Barchitta; Andrea Maugeri; Giuliana Favara; Roberta Magnano San Lio; Angelo Rossini; Raffaele Squeri; Cristina Genovese; Smeralda D'Amato; Vincenza La Fauci; Stefano Tardivo; Francesca Moretti; Alberto Carli; Beatrice Casini; Angelo Baggiani; Marco Verani; Anna Rita Giuliani; Leila Fabiani; Silvia D’Eugenio; Giovanni Boccia; Emanuela Santoro; Giovanni Battista Orsi; Christian Napoli; Marzia Montesano; Stefania Berdini; Enrico Bertamino; Antonio Perre; Alessandro Zerbetto; Marcello D’Errico; Sandro Ortolani; Maurizio Mercuri; Tiziana Traini; Adoriano Santarelli; Rita Fiorentini; Tiziana Benedetti; Maria Teresa Montagna; Simona Mascipinto; Ida Torre; Francesca Pennino; Daniela Schiavone; Anna Maria Iannicelli; Edoardo Tartaglia; Licia Veronesi; Lucia Palandri; Mariana Sao Miguel Morgado; Leandra Giudice; Cristina Arrigoni; Leandro Gentile; Barbara Bascapè; Ida Mura; Giovanni Sotgiu; Ilaria Barberis; Francesca Maria Bersi; Alessia Manca; Emanuela Massa; Alfredo Montecucco; Alborz Rahmani; Sonia Zacconi; Matteo Riccò; Nicola Magnavita; Reparata Rosa Di Prinzio; Maria Valeria Torregrossa; Giuseppe Calamusa; Alberto Firenze; Annalisa Bargellini; Paola Ferri; Elena Righi; Elisabetta Carraro; Alberto Borraccino; Deborah Traversi; Maria Chiara Ottino; Tatjana Baldovin; Sara Dalla Torre; Arda Sulaj; Ada Bianco; Valeria Teti; Roberto Novati; Roberta Oriani. 2020. "Predicting needlestick and sharps injuries in nursing students: Development of the SNNIP scale." Nursing Open 7, no. 5: 1578-1587.
Gp36 is the virus envelope glycoproteins catalyzing the fusion of the feline immunodeficiency virus with the host cells. The peptide C8 is a tryptophan-rich peptide corresponding to the fragment 770W-I777 of gp36 exerting antiviral activity by binding the membrane cell and inhibiting the virus entry. Several factors, including the membrane surface charge, regulate the binding of C8 to the lipid membrane. Based on the evidence that imperceptible variation of membrane charge may induce a dramatic effect in several critical biological events, in the present work we investigate the effect induced by systematic variation of charge in phospholipid bilayers on the aptitude of C8 to interact with lipid membranes, the tendency of C8 to assume specific conformational states and the re-organization of the lipid bilayer upon the interaction with C8. Accordingly, employing a bottom-up multiscale protocol, including CD, NMR, ESR spectroscopy, atomistic molecular dynamics simulations, and confocal microscopy, we studied C8 in six membrane models composed of different ratios of zwitterionic/negatively charged phospholipids. Our data show that charge content modulates C8-membrane binding with significant effects on the peptide conformations. C8 in micelle solution or in SUV formed by DPC or DOPC zwitterionic phospholipids assumes regular β-turn structures that are progressively destabilized as the concentration of negatively charged SDS or DOPG phospholipids exceed 40%. Interaction of C8 with zwitterionic membrane surface is mediated by Trp1 and Trp4 that are deepened in the membrane, forming H-bonds and cation-π interactions with the DOPC polar heads. Additional stabilizing salt bridge interactions involve Glu2 and Asp3. MD and ESR data show that the C8-membrane affinity increases as the concentration of zwitterionic phospholipid increases. In the lipid membrane characterized by an excess of zwitterionic phospholipids, C8 is adsorbed at the membrane interface, inducing a stiffening of the outer region of the DOPC bilayer. However, the bound of C8 significantly perturbs the whole organization of lipid bilayer resulting in membrane remodeling. These events, measurable as a variation of the bilayer thickness, are the onset mechanism of the membrane fusion and vesicle tubulation observed in confocal microscopy by imaging zwitterionic MLVs in the presence of C8 peptide.
Daniele Di Marino; Agostino Bruno; Manuela Grimaldi; Mario Scrima; Ilaria Stillitano; Giuseppina Amodio; Grazia Della Sala; Alice Romagnoli; Augusta De Santis; Ornella Moltedo; Paolo Remondelli; Giovanni Boccia; Gerardino D'Errico; Anna Maria D'Ursi; Vittorio Limongelli. Binding of the Anti-FIV Peptide C8 to Differently Charged Membrane Models: From First Docking to Membrane Tubulation. Frontiers in Chemistry 2020, 8, 493 .
AMA StyleDaniele Di Marino, Agostino Bruno, Manuela Grimaldi, Mario Scrima, Ilaria Stillitano, Giuseppina Amodio, Grazia Della Sala, Alice Romagnoli, Augusta De Santis, Ornella Moltedo, Paolo Remondelli, Giovanni Boccia, Gerardino D'Errico, Anna Maria D'Ursi, Vittorio Limongelli. Binding of the Anti-FIV Peptide C8 to Differently Charged Membrane Models: From First Docking to Membrane Tubulation. Frontiers in Chemistry. 2020; 8 ():493.
Chicago/Turabian StyleDaniele Di Marino; Agostino Bruno; Manuela Grimaldi; Mario Scrima; Ilaria Stillitano; Giuseppina Amodio; Grazia Della Sala; Alice Romagnoli; Augusta De Santis; Ornella Moltedo; Paolo Remondelli; Giovanni Boccia; Gerardino D'Errico; Anna Maria D'Ursi; Vittorio Limongelli. 2020. "Binding of the Anti-FIV Peptide C8 to Differently Charged Membrane Models: From First Docking to Membrane Tubulation." Frontiers in Chemistry 8, no. : 493.
The following study aims to verify whether psychosocial risk conditions determine a variation in personality traits. The sample consisted of 301 teachers, comprising 84 men (27.1%) and 217 women (72.9%). The Big Five Questionnaire (BFQ) was used to measure personality traits, while the Organizational and Psychosocial Risk Assessment (OPRA) questionnaire was used to measure psychosocial risk. The ANOVA results notice the change of BFQ traits. These are significant (Extraversion = 0.000; Agreeableness = 0.001; Neuroticism = 0.000; Openness = 0.017), with the exception of the Conscientiousness trait (Conscientiousness = 0.213). The research supports the approach of seeing personality as the result of the interaction between the individual and the environment; this position is also recognized by work-related stress literature. Stress conditions can lead to a change in the state of health and possibly determine the onset of work-related stress diseases. In the future, it would be useful to start a series of longitudinal studies to understand in greater detail the variability of personality traits due to changes in the Risk Index.
Ruggero Andrisano Ruggieri; Anna Iervolino; Piergiorgio Mossi; Emanuela Santoro; Giovanni Boccia. Instability of Personality Traits of Teachers in Risk Conditions due to Work-Related Stress. Behavioral Sciences 2020, 10, 91 .
AMA StyleRuggero Andrisano Ruggieri, Anna Iervolino, Piergiorgio Mossi, Emanuela Santoro, Giovanni Boccia. Instability of Personality Traits of Teachers in Risk Conditions due to Work-Related Stress. Behavioral Sciences. 2020; 10 (5):91.
Chicago/Turabian StyleRuggero Andrisano Ruggieri; Anna Iervolino; Piergiorgio Mossi; Emanuela Santoro; Giovanni Boccia. 2020. "Instability of Personality Traits of Teachers in Risk Conditions due to Work-Related Stress." Behavioral Sciences 10, no. 5: 91.
M T Montagna; S Mascipinto; C Pousis; F P Bianchi; G Caggiano; L F Carpagnano; Osvalda De Giglio; G Barbuti; F Auxilia; A Destrebecq; S Castaldi; T Baldovin; Annalisa Bargellini; Elena Righi; Giovanni Boccia; E Santoro; B Casini; A Baggiani; R Novati; R Oriani; A Odone; A G Mezzoiuso; G B Orsi; Christian Napoli; C Pasquarella; Licia Veronesi; G Ripabelli; M L Sammarco; A Rossini; R Squeri; P Laganà; G M Antonuccio; Cristina Genovese; S Tardivo; I Torre; Rossella Alfano; F Pennino; M V Torregrossa; M Barchitta; A Agodi. Knowledge, experiences, and attitudes toward Mantoux test among medical and health professional students in Italy: a cross-sectional study. Annali di igiene : medicina preventiva e di comunita 2018, 30, 86 -98.
AMA StyleM T Montagna, S Mascipinto, C Pousis, F P Bianchi, G Caggiano, L F Carpagnano, Osvalda De Giglio, G Barbuti, F Auxilia, A Destrebecq, S Castaldi, T Baldovin, Annalisa Bargellini, Elena Righi, Giovanni Boccia, E Santoro, B Casini, A Baggiani, R Novati, R Oriani, A Odone, A G Mezzoiuso, G B Orsi, Christian Napoli, C Pasquarella, Licia Veronesi, G Ripabelli, M L Sammarco, A Rossini, R Squeri, P Laganà, G M Antonuccio, Cristina Genovese, S Tardivo, I Torre, Rossella Alfano, F Pennino, M V Torregrossa, M Barchitta, A Agodi. Knowledge, experiences, and attitudes toward Mantoux test among medical and health professional students in Italy: a cross-sectional study. Annali di igiene : medicina preventiva e di comunita. 2018; 30 ():86-98.
Chicago/Turabian StyleM T Montagna; S Mascipinto; C Pousis; F P Bianchi; G Caggiano; L F Carpagnano; Osvalda De Giglio; G Barbuti; F Auxilia; A Destrebecq; S Castaldi; T Baldovin; Annalisa Bargellini; Elena Righi; Giovanni Boccia; E Santoro; B Casini; A Baggiani; R Novati; R Oriani; A Odone; A G Mezzoiuso; G B Orsi; Christian Napoli; C Pasquarella; Licia Veronesi; G Ripabelli; M L Sammarco; A Rossini; R Squeri; P Laganà; G M Antonuccio; Cristina Genovese; S Tardivo; I Torre; Rossella Alfano; F Pennino; M V Torregrossa; M Barchitta; A Agodi. 2018. "Knowledge, experiences, and attitudes toward Mantoux test among medical and health professional students in Italy: a cross-sectional study." Annali di igiene : medicina preventiva e di comunita 30, no. : 86-98.
Silvano Esposito; Silvana Noviello; Francesco De Caro; Giovanni Boccia. New insights into classification, epidemiology and microbiology of SSTIs, including diabetic foot infections. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 2018, 26, 3 -14.
AMA StyleSilvano Esposito, Silvana Noviello, Francesco De Caro, Giovanni Boccia. New insights into classification, epidemiology and microbiology of SSTIs, including diabetic foot infections. Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive. 2018; 26 (1):3-14.
Chicago/Turabian StyleSilvano Esposito; Silvana Noviello; Francesco De Caro; Giovanni Boccia. 2018. "New insights into classification, epidemiology and microbiology of SSTIs, including diabetic foot infections." Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 26, no. 1: 3-14.
Ruggero Andrisano-Ruggieri; Pietro Crescenzo; Mario Capunzo; Francesco DE Caro; Riccardo Savastano; Manuela Pennisi; Giovanni Boccia. Understanding the relationship between Sentinel Events and Sources of Work Related Stress for prevention programmes. An Italian survey. Giornale italiano di medicina del lavoro ed ergonomia 2017, 39, 39 -41.
AMA StyleRuggero Andrisano-Ruggieri, Pietro Crescenzo, Mario Capunzo, Francesco DE Caro, Riccardo Savastano, Manuela Pennisi, Giovanni Boccia. Understanding the relationship between Sentinel Events and Sources of Work Related Stress for prevention programmes. An Italian survey. Giornale italiano di medicina del lavoro ed ergonomia. 2017; 39 (1):39-41.
Chicago/Turabian StyleRuggero Andrisano-Ruggieri; Pietro Crescenzo; Mario Capunzo; Francesco DE Caro; Riccardo Savastano; Manuela Pennisi; Giovanni Boccia. 2017. "Understanding the relationship between Sentinel Events and Sources of Work Related Stress for prevention programmes. An Italian survey." Giornale italiano di medicina del lavoro ed ergonomia 39, no. 1: 39-41.