A strategy for regularizing the inversion procedure for the two-dimensional D-bar reconstruction algorithm based on the global uniqueness proof of Nachman [Ann. Math. 143 (1996)] for the ill-posed inverse conductivity problem is presented. The strategy utilizes truncation of the boundary integral equation and the scattering transform. It is shown that this leads to a bound on the error in the scattering transform and a stable reconstruction of the conductivity; an explicit rate of convergence in appropriate Banach spaces is derived as well. Numerical results are also included, demonstrating the convergence of the reconstructed conductivity to the true conductivity as the noise level tends to zero. The results provide a link between two traditions of inverse problems research: theory of regularization and inversion methods based on complex geometrical optics. Also, the procedure is a novel regularized imaging method for electrical impedance tomography.

Electrical impedance tomography (EIT) is an imaging modality where a patient or object is probed using harmless electric currents. The currents are fed through electrodes placed on the surface of the target, and the data consists of voltages measured at the electrodes resulting from a linearly independent set of current injection patterns. EIT aims to recover the internal distribution of electrical conductivity inside the target. The inverse problem underlying the EIT image formation task is nonlinear and severely ill-posed, and hence sensitive to modeling errors and measurement noise. Therefore, the inversion process needs to be regularized. However, traditional variational regularization methods, based on optimization, often suffer from local minima because of nonlinearity. This is what makes regularized direct (non-iterative) methods attractive for EIT. The most developed direct EIT algorithm is the D-bar method, based on complex geometric optics solutions and a nonlinear Fourier transform. Variants and recent developments of D-bar methods are reviewed, and their practical numerical implementation is explained.

The pioneering work ''On an inverse boundary value problem'' by A. Calderón has inspired a multitude of research, both theoretical and numerical, on the inverse conductivity problem (ICP). The problem has an important application in a medical imaging technique known as electrical impedance tomography (EIT) in which currents are applied on electrodes on the surface of a body, the resulting voltages are measured, and the ICP is solved to determine the conductivity distribution in the interior of the body, which is then displayed to form an image. In this article, the reconstruction method proposed by Calderón is implemented in 2D for both simulated and experimental data including perfusion data collected on a human chest.

The design and performance of the active complex electrode (ACE1) electrical impedance tomography system for single-ended phasic voltage measurements are presented. The design of the hardware and calibration procedures allows for reconstruction of conductivity and permittivity images. Phase measurement is achieved with the ACE1 active electrode circuit which measures the amplitude and phase of the voltage and the applied current at the location at which current is injected into the body. An evaluation of the system performance under typical operating conditions includes details of demodulation and calibration and an in-depth look at insightful metrics, such as signal-to-noise ratio variations during a single current pattern. Static and dynamic images of conductivity and permittivity are presented from ACE1 data collected on tank phantoms and human subjects to illustrate the system's utility.

The aim of this paper is to show the feasibility of the D-bar method for real-time 2-D EIT reconstructions. A fast implementation of the D-bar method for reconstructing conductivity changes on a 2-D chest-shaped domain is described. Cross-sectional difference images from the chest of a healthy human subject are presented, demonstrating what can be achieved in real time. The images constitute the first D-bar images from EIT data on a human subject collected on a pairwise current injection system.

Objective: Medical electrical impedance tomography is a non-ionizing imaging modality in which low-amplitude, low-frequency currents are applied on electrodes on the body, the resulting voltages are measured, and an inverse problem is solved to determine the conductivity distribution in the region of interest. Due the ill-posedness of the inverse problem, the boundaries of internal organs are typically blurred in the reconstructed image. Methods: A deep learning approach is introduced in the D-bar method for reconstructing a 2-D slice of the thorax to recover the boundaries of organs. This is accomplished by training a deep neural network on labeled pairs of scattering transforms and the boundaries of the organs in the data from which the transforms were computed. This allows the network to “learn” the nonlinear mapping between them by minimizing the error between the output of the network and known actual boundaries. Further, a “sparse” reconstruction is computed by fusing the results of the standard D-bar reconstruction with reconstructed organ boundaries from the neural network. Results: Results are shown on simulated and experimental data collected on a saline-filled tank with agar targets simulating the conductivity of the heart and lungs. Conclusions and Significance: The results demonstrate that deep neural networks can successfully learn the mapping between scattering transforms and the internal boundaries of structures.