Internet of Things (IoT) and Network Softwarization are fast becoming core technologies of information systems and network management for the next-generation Internet. The deployment and applications of IoT range from smart cities to urban computing and from ubiquitous healthcare to tactile Internet. For this reason, the physical infrastructure of heterogeneous network systems has become more complicated and thus requires efficient and dynamic solutions for management, configuration, and flow scheduling. Network softwarization in the form of Software Defined Networks and Network Function Virtualization has been extensively researched for IoT in the recent past. In this article, we present a systematic and comprehensive review of virtualization techniques explicitly designed for IoT networks. We have classified the literature into software-defined networks designed for IoT, function virtualization for IoT networks, and software-defined IoT networks. These categories are further divided into works that present architectural, security, and management solutions. Besides, the article highlights several short-term and long-term research challenges and open issues related to the adoption of software-defined Internet of Things.

E-health systems have witnessed widespread usage in the last few years, mainly due to advancements in health monitoring hardware and the availability of remote diagnostic services. Given the numerous benefits, there are two main challenges: management of the e-health ecosystem and security and privacy of sensitive data. The former results from nonunified, redundant, and often replicated information across numerous independent e-health service providers. While the later stems from sensitive information stored in centralized systems that can be compromised. Blockchain has emerged as a promising technology, which can be used to secure access and privacy of data and provide an umbrella management solution to large-scale distributed and decentralized enterprise systems. In this article, we present a unified system for migrating independent conventional e-health systems to a single blockchain-based ecosystem. More specifically, we address the issues of difference in data structures for conventional relational databases and blockchain file databases. The solution describes the conversion process and synchronization of information in a unified system for large-scale e-health data. The implementation and analysis show that significant improvements in data storage, access control, and seamless migration can be achieved.

Contagious diseases are prevalent even in the current era of advanced technology. A uniformed initiative is required to build a reliable interactive information exchange service targeting vaccination data management and other medical services. The conventional data exchange mechanism is centralized, creating many vulnerable issues such as a single point failure, data leakage, access control, etc. This article introduces a Blockchain-based medical data-sharing framework (called GlobeChain) to overcome the technical challenges to handle the outbreak records. The challenges that might arise due to the proposed Blockchain-based framework are also presented as a future direction that grabs the proposal's effectiveness.