The extensive deployment of wireless infrastructure provides a low-cost way to track mobile users in indoor environment. This paper demonstrates a prototype model of an accurate and reliable room location awareness system in a real public environment in which three typical problems arise. Firstly, a massive number of access points (APs) can be sensed leading to a high-dimensional classification problem. Secondly, heterogeneous devices record different received signal strength (RSS) levels because of the variations in chip-set and antenna attenuation. Thirdly, APs are not necessarily visible in every scanning cycle leading to missing data issue. This paper presents a probabilistic Wi-Fi fingerprinting method in a hidden Markov model (HMM) framework for mobile user tracking. To account for spatial correlation of the signal strengths from multiple APs, a Multivariate Gaussian Mixture Model (MVGMM) was fitted to model the probability distribution of RSS measurements in each cell. Furthermore, the unseen property of invisible AP was investigated in this research, and demonstrated the efficiency as a beneficial information to differentiate between cells. The proposed system is able to achieve comparable localisation performance. Filed test results achieve a reliable 97% localisation room level accuracy of multiple mobile users in a real university campus Wi-Fi network.

The use of spatial maps to navigate through the world requires a complex ongoing transformation of egocentric views of the environment into position within the allocentric map. Recent research has discovered neurons in retrosplenial cortex and other structures that could mediate the transformation from egocentric views to allocentric views. These egocentric boundary cells respond to the egocentric direction and distance of barriers relative to an animal's point of view. This egocentric coding based on the visual features of barriers would seem to require complex dynamics of cortical interactions. However, computational models presented here show that egocentric boundary cells can be generated with a remarkably simple synaptic learning rule that forms a sparse representation of visual input as an animal explores the environment. Simulation of this simple sparse synaptic modification generates a population of egocentric boundary cells with distributions of direction and distance coding that strikingly resemble those observed within the retrosplenial cortex. Furthermore, some egocentric boundary cells learnt by the model can still function in new environments without retraining. This provides a framework for understanding the properties of neuronal populations in the retrosplenial cortex that may be essential for interfacing egocentric sensory information with allocentric spatial maps of the world formed by neurons in downstream areas, including the grid cells in entorhinal cortex and place cells in the hippocampus.SIGNIFICANCE STATEMENTThe computational model presented here demonstrates that the recently discovered egocentric boundary cells in retrosplenial cortex can be generated with a remarkably simple synaptic learning rule that forms a sparse representation of visual input as an animal explores the environment. Additionally, our model generates a population of egocentric boundary cells with distributions of direction and distance coding that strikingly resemble those observed within the retrosplenial cortex. This transformation between sensory input and egocentric representation in the navigational system could have implications for the way in which egocentric and allocentric representations interface in other brain areas.

In problems of parameter estimation from sensor data, the Fisher information provides a measure of the performance of the sensor; effectively, in an infinitesimal sense, how much information about the parameters can be obtained from the measurements. From the geometric viewpoint, it is a Riemannian metric on the manifold of parameters of the observed system. In this paper, we consider the case of parameterized sensors and answer the question, “How best to reconfigure a sensor (vary the parameters of the sensor) to optimize the information collected?” A change in the sensor parameters results in a corresponding change to the metric. We show that the change in information due to reconfiguration exactly corresponds to the natural metric on the infinite-dimensional space of Riemannian metrics on the parameter manifold, restricted to finite-dimensional sub-manifold determined by the sensor parameters. The distance measure on this configuration manifold is shown to provide optimal, dynamic sensor reconfiguration based on an information criterion. Geodesics on the configuration manifold are shown to optimize the information gain but only if the change is made at a certain rate. An example of configuring two bearings-only sensors to optimally locate a target is developed in detail to illustrate the mathematical machinery, with Fast Marching methods employed to efficiently calculate the geodesics and illustrate the practicality of using this approach.

The use of spatial maps to navigate through the world requires a complex ongoing transformation of egocentric views of the environment into position within the allocentric map. Recent research has discovered neurons in retrosplenial cortex and other structures that could mediate the transformation from egocentric views to allocentric views. These egocentric boundary cells respond to the egocentric direction and distance of barriers relative to an animals point of view. This egocentric coding based on the visual features of barriers would seem to require complex dynamics of cortical interactions. However, computational models presented here show that egocentric boundary cells can be generated with a remarkably simple synaptic learning rule that forms a sparse representation of visual input as an animal explores the environment. Simulation of this simple sparse synaptic modification generates a population of egocentric boundary cells with distributions of direction and distance coding that strikingly resemble those observed within the retrosplenial cortex. This provides a framework for understanding the properties of neuronal populations in the retrosplenial cortex that may be essential for interfacing egocentric sensory information with allocentric spatial maps of the world formed by neurons in downstream areas including the grid cells in entorhinal cortex and place cells in the hippocampus.

Introduction: Inhibitory G proteins are known to mediate vagal influences on the heart. However, their role in the central nervous mechanisms of cardiovascular control remains unclear. The relative contribution of central autonomic tone to arrhythmogenesis is also poorly understood. Previous data have shown mice with global deletion of GalphaO (GαO) exhibit tachycardia, loss of diurnal variation and a heart rate variability phenotype suggestive of increased sympathetic tone, likely to be of central origin (1). We hence hypothesised that in mice, conditional deletion of GαO in the rostral ventrolateral medulla oblongata (RVLM), which contains sympathoexcitatory (pre-sympathetic) neurones, will have a significant impact on autonomic cardiac reflexes and may predispose to cardiac arrhythmias.