Industrial spray coating processes are known to produce excellent coatings on large surfaces and are thus often used for in-line production. However, they could be one of the most critical sources of worker exposure to ultrafine particles (UFPs). A monitoring campaign at the Witek s.r.l. (Florence, Italy) was deployed to characterize the release of TiO₂ NPs doped with nitrogen (TiO₂-N) and Ag capped with hydroxyethyl cellulose (AgHEC) during automatic industrial spray-coating of polymethyl methacrylate (PMMA) and polyester. Aerosol particles were characterized inside the spray chamber at near field (NF) and far field (FF) locations using on-line and off-line instruments. Results showed that TiO₂-N suspension produced higher particle number concentrations than AgHEC in the size range 0.3–1 µm (on average 1.9 10² p/cm³ and 2.5 10¹ p/cm³, respectively) after background removing. At FF, especially at worst case scenario (4 nozzles, 800 mL/min flow rate) for TiO₂-N, the spray spikes were correlated with NF, with an observed time lag of 1 minute corresponding to a diffusion speed of 0.1 m/s. The averaged ratio between particles mass concentrations in the NF position and inside the spray chamber was 1.7% and 1.5% for TiO₂-N and for AgHEC suspensions, respectively. The released particles’ number concentration of TiO₂-N in the size particles range 0.3–1 µm was comparable for both PMMA and polyester substrates, about 1.5 and 1.6 10² p/cm³. In the size range 0.01–30 µm, the aerosol number concentration at NF for both suspensions was lower than the nano reference values (NRVs) of 16·10³ p/cm^-3.

An automatic lab-scaled spray-coating machine was used to deposit Ag nanoparticles (AgNPs) on textile to create antibacterial fabric. The spray process was monitored for the dual purpose of (1) optimizing the process by maximizing silver deposition and minimizing fluid waste, thereby reducing suspension consumption and (2) assessing AgNPs release. Monitoring measurements were carried out at two locations: inside and outside the spray chamber (far field). We calculated the deposition efficiency (E), finding it to be enhanced by increasing the spray pressure from 1 to 1.5 bar, but to be lowered when the number of operating sprays was increased, demonstrating the multiple spray system to be less efficient than a single spray. Far-field AgNPs emission showed a particle concentration increase of less than 10% as compared to the background level. This finding suggests that under our experimental conditions, our spray-coating process is not a critical source of worker exposure.

In this paper, we demonstrate the realization process of a pragmatic approach on developing a template for capturing field monitoring data in nanomanufacturing processes. The template serves the fundamental principles which make data scientifically Findable, Accessible, Interoperable and Reusable (FAIR principles), as well as encouraging individuals to reuse it. In our case, the data shepherds’ (the guider of data) template creation workflow consists of the following steps: (1) Identify relevant stakeholders, (2) Distribute questionnaires to capture a general description of the data to be generated, (3) Understand the needs and requirements of each stakeholder, (4) Interactive simple communication with the stakeholders for variables/descriptors selection, and (5) Design of the template and annotation of descriptors. We provide an annotated template for capturing exposure field campaign monitoring data, and increase their interoperability, while comparing it with existing templates. This paper enables the data creators of exposure field campaign data to store data in a FAIR way and helps the scientific community, such as data shepherds, by avoiding extensive steps for template creation and by utilizing the pragmatic structure and/or the template proposed herein, in the case of a nanotechnology project (Anticipating Safety Issues at the Design of Nano Product Development, ASINA).

Spray coatings’ emissions impact to the environmental and occupational exposure were studied in a pilot-plant. Concentrations were measured inside the spray chamber and at the work room in Near-Field (NF) and Far-Field (FF) and mass flows were analyzed using a mechanistic model. The coating was performed in a ventilated chamber by spraying titanium dioxide doped with nitrogen (TiO₂N) and silver capped by hydroxyethylcellulose (Ag-HEC) nanoparticles (NPs). Process emission rates to workplace, air, and outdoor air were characterized according to process parameters, which were used to assess emission factors. Full-scale production exposure potential was estimated under reasonable worst-case (RWC) conditions. The measured TiO₂-N and Ag-HEC concentrations were 40.9 TiO₂-μg/m³ and 0.4 Ag-μg/m³ at NF (total fraction). Under simulated RWC conditions with precautionary emission rate estimates, the worker’s 95th percentile 8-h exposure was ≤171 TiO₂ and ≤1.9 Ag-μg/m³ (total fraction). Environmental emissions via local ventilation (LEV) exhaust were ca. 35 and 140 mg-NP/g-NP, for TiO₂-N and Ag-HEC, respectively. Under current situation, the exposure was adequately controlled. However, under full scale production with continuous process workers exposure should be evaluated with personal sampling if recommended occupational exposure levels for nanosized TiO₂ and Ag are followed for risk management.

Anisotropic colloidal geometry is used to drive lipid sorting in multi-component membranes along the colloids, which are then exploited to create “shape-anisotropic patchy colloids” for directed self-assembly.