Background: No systematic review or meta-analysis has yet been performed to examine the global prevalence of nomophobia by population, by instrument. Thus, this review was performed to estimate the prevalence of nomophobia by severity. Methods: American Psychological Association PsycINFO, Cochrane, Cumulative Index to Nursing and Allied Health Literature (CINAHL), EBSCOhost, EMBASE, MEDLINE, ProQuest Medical, ScienceDirect, Scopus, and Web of Science from inception of each respective database to second week of January 2021 were used. There was no language restriction. The random-effect meta-analysis model was used with the DerSimonian and Laird methodology was used for computation. Results: Twenty papers, involving 12,462 participants from ten countries, were evaluated for meta-analysis. The prevalence of moderate to severe nomophobia is 70.76% [95% CI 62.62%; 77.75%]. The prevalence of severe nomophobia is 20.81% [95% CI 15.45%; 27.43%]. University students appeared to be the highest group affected with a prevalence of severe nomophobia 25.46% [95% CI 18.49%; 33.98%]. Meta-regressions of severe nomophobia showed that age and sex were not a successful predictor of severe nomophobia β = −0.9732, p = 0.2672 and β = −0.9732, p = 0.4986. Conclusions: The prevalence of severe nomophobia is approximately 21% in the general adult population. University students appeared to be the most impacted by the disorder.

Lupus erythematosus profundus, also known as lupus panniculitis, is a rare subtype of cutaneous lupus erythematosus characterized by inflammatory involvement of the deep dermis and subcutaneous adipose tissue. It is predominantly reported in adults, whereas pediatric presentations remain uncommon. A five-year-old Middle Eastern girl presented with a two-month history of progressive localized alopecia involving the left parietal scalp, associated with perioral swelling predominantly affecting the upper lip. Examination showed an alopecic patch measuring approximately 4 × 2 cm with reduced follicular openings, suggestive of early scarring alopecia, and diffuse upper lip swelling with surrounding mild erythema. Trichoscopy demonstrated decreased follicular density and areas of absent follicles. Laboratory evaluation revealed elevated inflammatory markers with negative antinuclear antibody testing and normal complement levels. Histopathological examination of scalp and nasolabial fold biopsies demonstrated predominant lobular lymphocytic and histiocytic panniculitis extending into the subcutaneous fat, consistent with lupus erythematosus profundus. Treatment with oral hydroxychloroquine led to significant improvement in lip swelling and stabilization of the scalp lesion, with subsequent hair regrowth on follow-up. Lupus erythematosus profundus is an uncommon but important cause of localized alopecia and facial swelling in children. Early clinicopathologic recognition and timely treatment are essential to reduce the risk of permanent scarring and disfigurement.